Preventing muscle loss through early mobilization in non-critically ill older adults admitted to surgical intensive care units by Onuma Chaiwat, Thanadol Wachiramatee, Benjaporn Sathitkarnmanee, Suchera Rattanamung, Piyapat Dajpratham, Napat Thikom, Chayanan Thanakiattiwibun

“…Functional status 1 week post-discharge was measured by telephone using the Barthel Index for activities of daily living (ADL). …”
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Long-Term Aerobic Exercise Enhances Hepatoprotection in MAFLD by Modulating Exosomal miR-324 via ROCK1 by Yang Zhang, Qiangman Wei, Xue Geng, Guoliang Fang

“…Functional assays demonstrated that miR-324 modulates insulin resistance by targeting ROCK1. …”
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MAFF mitigates oxidative stress and pyroptosis in cardiopulmonary bypass-induced myocardium injury by Lei Yuan, Duo Wang, Yale Su, Long Yuan, Mixia Li, Dongdong Zheng, Cuilin Zhu, Hulin Piao, Yong Wang, Zhicheng Zhu, Dan Li, Tiance Wang, Kexiang Liu

“…Through systematic validation, we identified the most representative hub gene. Subsequent functional studies, including gene knockdown and overexpression experiments, were conducted to elucidate its role and underlying mechanisms in oxidative stress-induced cardiomyocyte injury.ResultsIntegrated bioinformatics analysis and experimental validation identified MAFF as the most differentially expressed hub gene between pre- and post-CPB conditions. …”
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Noninvasive anatomical assessment for ruling out hemodynamically relevant coronary artery anomalies in adults – A comparison of coronary-CT to invasive coronary angiography: The NA... by Marius R. Bigler, Anselm W. Stark, Isaac Shiri, Joel Illi, Matthias Siepe, Federico Caobelli, Andreas A. Giannopoulos, Ronny R. Buechel, Andreas Haeberlin, Dominik Obrist, Lorenz Räber, Christoph Gräni

“…As the sole presence of AAOCA does not always imply a revascularization, a detailed anatomical and functional analysis is crucial for clinical decision-making. …”
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Regulation of α-Ketoglutarate levels by Myc affects metabolism and demethylation in porcine early embryos by Ran Ding, Yongfeng Zhou, Qi Zhang, Xiangjie Kong, Qi Li, Sheng Zhang, Yibing Chen, Xinglan An, Ziyi Li

“…Mechanistically, these effects were dependent on α-KG, a TCA cycle intermediate and cofactor for TET demethylation enzymes. Sequencing analysis of four-cell embryos post-Myc inhibition revealed downregulation of key metabolic enzymes related to α-KG, such as CS, IDH2, leading to reduced α-KG levels. …”
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Uncommon but intriguing: A pediatric primary histiocytic sarcoma case—Clinical insights and literature review by Sofia Elouaouch, MD, Soufiane Berhili, MD, Hanane Mansouri, MD, Zahira El Youssi, MD, Ahmed Bensghier, MD, Mohammed Moukhlissi, MD, Karim Bahhous, PhD, Loubna Mezouar, MD

“…Following R1 surgical resection, the patient received adjuvant radiotherapy (43 Gy to the tumor bed and 36.9 Gy to the inguinal region) and OEPAbased chemotherapy. At 20 months post-treatment, the patient remains in remission with excellent functional outcomes. …”
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Nutrition and Antioxidant Potential of Three Cauliflower (Brassica oleracea L. Var. Botrytis) Cultivars Cultivated in Southern Part of Bangladesh by Mousumi Jahan Sumi, Sharmin Akter Serity, Tusar Kanti Roy, Keya Akter, Shishir Rasul, Mostofa Jaman Depro, Md. Masum Abdullah, Md. Nesar Uddin

“…Uniform curds were harvested at 60 days post-sowing from Baratia, Dumuria, Khulna, and analyzed at Khulna Agricultural University. …”
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SAFETY OF CANNED MILK AS AN INTEGRATED CRITERION OF THEIR TECHNOLOGY EFFECTIVENESS. RUSSIAN EXPERIENCE by S. N. Turovskaya, A. G. Galstyan, A. N. Petrov, I. A. Radaeva, E. E. Illarionovа, V. K. Semipyatniy, S. A. Khurshudyan

“…The system of ensuring the stabilization of canned milk in storage is represented by two main blocks: technologically formed potential and post-technological requirements for its maintenance. …”
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Structure-Based Design of Small-Molecule Inhibitors of Human Interleukin-6 by Ankit Joshi, Zhousheng Xiao, Shreya Suman, Connor Cooper, Khanh Ha, James A. Carson, Leigh Darryl Quarles, Jeremy C. Smith, Madhulika Gupta

“…The top 20 scoring ligands from the in silico studies after post analysis were subjected to in vitro functional assays. …”
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Vaccine-induced T cell responses correlate with reduced risk of severe COVID-19 in a placebo-controlled efficacy trialResearch in context by Nina Hertoghs, Sanne Roels, Matthias Brückner, Jerald Sadoff, Barbara L. Banbury, Nicholas K. Akers, Bryan Howie, Harlan S. Robins, Griet A. van Roey, Jeroen T.B.M. Tolboom, Veronica V. Rezelj, Jenny Hendriks, Hanneke Schuitemaker, Daniel J. Stieh, Mathieu Le Gars

“…Methods: T cell receptor (TCR) sequencing was conducted using pre-vaccination and 29 days post-vaccination PAXgene samples from 396 participants in the phase 3 efficacy trial, ENSEMBLE. …”
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Cognitive behavioral therapy for depression in Japanese Parkinson's disease patients: a pilot study by Shinmei I, Kobayashi K, Oe Y, Takagishi Y, Kanie A, Ito M, Takebayashi Y, Murata M, Horikoshi M, Dobbin RD

“…Most of the secondary outcome measurements showed a small-to-moderate but nonsignificant effect size from baseline to post-intervention.Conclusion: This study provides preliminary evidence that CBT is feasible among Japanese PD patients with depression. …”
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Effects of foliar selenium spraying on the growth and selenium content and morphology of rice by Wenxia Pei, Mengya Dai, Sheng Shi, Yuan Zhang, Daxia Wu, Cece Qiao, Yafei Sun, Jianfei Wang

“…Foliar Se application also increased the total organic Se and different organic Se forms contents in grains and altered its composition by reducing the proportion of RNA-bound Se. Temporal analysis revealed that total Se concentrations in rice tissues rose sharply within the first 14 days post-application, followed by a decline in vegetative tissues but a continued increase in grains after 31 days. …”
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Integrating multi-omics and experimental techniques to decode ubiquitinated protein modifications in hepatocellular carcinoma by Haikun Yang, Yuan Chen, Yuan Chen, Zheng Zhou, Yanjing Wang, Peng Li, Yang Li

“…BackgroundUbiquitination, a critical post-translational modification, plays a pivotal role in regulating protein stability and activity, influencing various aspects of cancer development, including metabolic reprogramming, immune evasion, and tumor progression. …”
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Influencing mechanisms of microwave radiation duration on the efficiency of methane adsorption in coals by Yiliang HU, Yuan BAO, Jiahao MENG, Xueru CHEN, Tuo SHAN

“…Furthermore, it examined the correlation between the structural parameters and methane adsorption parameters of coals post-radiation using multivariate statistical analysis. …”
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The Employment of Orthodontic Bracket System as Method of Intermaxillary Fixation in Cases of Traumatic Mandibular Fractures: Retrospective Literary Review and Own Experience by Vares Ya., Chegrynec N.

“…Control inspection of patients was carried out on 1, 3, 7, 14, 21, 30, 60 and 90 days post-operatively. Results. The obtained results of employment of non-removable orthodontic elements (brackets) for bone fragments fixation in 22 patients with traumatic mandibular fractures were evaluated by us as satisfactory. …”
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GNNs and ensemble models enhance the prediction of new sRNA-mRNA interactions in unseen conditions by Shani Cohen, Lior Rokach, Isana Veksler-Lublinsky

“…Abstract Bacterial small RNAs (sRNAs) are pivotal in post-transcriptional regulation, affecting functions like virulence, metabolism, and gene expression by binding specific mRNA targets. …”
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From isolation to detection, advancing insights into endothelial matrix-bound vesicles by Sahimy Ayus-Martinez, William Meza-Morales, Jesus Jimenez-Osorio, Maria Buendia-Otero, Luis López, Lisandro Cunci, Donald O. Freytes, Camilo Mora

“…Moreover, we developed a prototype of an immuno-functionalized screen-printed electrode designed for the immunoadsorption of CD144+ MBVs. …”
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Nanoparticle-mediated SIRT1 inhibition suppresses M2 macrophage polarization and hepatocarcinogenesis in chronic hepatitis B by He Zhang, Feng Yuan, Nan Zhao, Wenqiang Tang, Pengwei Zhao, Chunfa Liu, Shan Chen, Xiaolin Hou, Changyou Xia, Jun Chu

“…Functional enrichment analysis highlighted key pathways, including PI3K-Akt and NF-κB, that contribute to CHB-driven immune alterations. …”
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Association of Vitamin E with Rapid Thawing on Goat Semen by Jurandy Mauro Penitente-Filho, Fabrício Albani Oliveira, Carolina Rodriguez Jimenez, Erly Carrascal, Júlio César Oliveira Dias, Gisele Dias Oliveira, Renata Gomes Silveira, Camila Oliveira Silveira, Ciro Alexandre Alves Torres

“…Nevertheless, defrosting rate of 60°C/7 seconds improved sperm membrane functional integrity (P<0.05). Current knowledge about goat semen cryopreservation is not sufficient to ensure high post-thawing recovery rates; thus, this study brings important data about using antioxidants and different thawing rates on cryopreservation process.…”
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A social media listening study of patients’ experiences relating to metabolic dysfunction-associated steatotic liver disease: The LISTEN-MASLD study by Jeffrey V. Lazarus, William Alazawi, Ron Basuroy, Laurent Castera, Dmitry Estulin, Yiannoula Koulla, Preethy Prasad, Manuel Romero-Gomez, Hirokazu Takahashi, Vincent Wai-Sun Wong, Jörn M. Schattenberg

“…Nearly 38 % of the posts mentioned that patients were emotionally affected by negative feelings, especially those with multiple comorbidities. …”
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