Authenticity in S, M, L, XL scale of Thessaloniki by Sotiria Alexiadou

“…The polykatoikia’s distinctive ownership model which divides the building into numerous individual ownerships [S scale], like flats and stores, enters a new era that affects significant aspects like the building’s uses and functions from a bottom-up view. The paper is based on the author's postdoctoral research (Alexiadou, 2024a); recent literature and case studies analysis of OEM buildings interventions support the objectives. …”
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The relationship between serum lipid levels and the risk of oral cancer by Jyoti G Chawda, Shikha S Jain, Hemali R Patel, Nandini Chaduvula, Kunal Patel

“…The values were then statistically analyzed using analysis of variance (ANOVA) and post hoc methods. …”
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Tracking teachers’ experience of adopting my English step to infuse differentiated instruction by Ilza Mayuni, Yinghui Chen, Ni Made Ratminingsih, Tara Mustikaning Palupi, Nurhasanah Halim

“…As a post-developmental study, this qualitative research is intended to evaluate teachers’ continued experience in adopting My English Step (MES) digital learning material and promoting inclusion in Differentiated Instruction (DI) at junior high school (JHS). …”
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Exploring the role of gut probiotic metabolites in the prevention and treatment of otitis media by Bo Zheng, Haiyong Jin

“…PPI interaction was used to identify the 10 hub targets. To understand the post-transcriptional regulation of these common genes, we identified miRNAs targeting them using the multiMiRR package.ResultsThe functional enrichment and disease association analyses of these genes and miRNAs revealed their significant involvement in inflammatory and immune regulatory pathways, many of which are shared with chronic otitis media pathogenesis.DiscussionOverall, this integrative approach established a strong link between gut microbial metabolites, their host gene targets, and miRNA-mediated regulatory mechanisms in otitis media. …”
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”Being ill was the easy part”: exploring cancer survivors’ reactions to perceived challenges in engaging with primary healthcare by Lars Garpenhag, Anders Halling, Susanna Calling, Linn Rosell, Anna-Maria Larsson

“…Data were analysed using a descriptive template analysis approach. Results In light of perceived challenges associated with access to adequate PHC, participants experienced that they had been forced to work hard to achieve functioning PHC contacts. …”
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Lactylation associated biomarkers and immune infiltration in aortic dissection by Jianfeng Ye, Yuntao Fu, Yuanjia Ke, Huanting Liu, Sini Fang, Yumeng Lei, Ying Mao, Liqiu Yan, Youcheng Wang

“…Transcriptomic data from public databases were analyzed to identify differentially expressed lactylation-related genes in AD. Functional enrichment analyses were performed, and Weighted Gene Co-expression Network Analysis (WGCNA) was utilized to identify gene modules associated with AD. …”
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Computational advances in the design and discovery of artemis inhibitors for radiosensitization in cancer therapy by Maryam Bashir, Usman Abdullah, Sadia Nazir, Farhan Siddique, Nasir Jalal

“…Compounds 42 and 51 were subjected to 100 ns molecular dynamics (MD) simulations with MMGBSA binding free energy calculations, PCA, and FEL analysis.ResultsCJ179 cells exhibited significantly higher micronuclei post-irradiation, confirming Artemis’s role in DNA repair. …”
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Impacts of Low-Order Stream Connectivity Restoration Projects on Aquatic Habitat and Fish Diversity by Xinfeng Li, Xuan Che, Xiaolong Chen, Changfeng Tian, Jiahua Zhang

“…Results indicate that (1) the post-restoration aquatic habitat significantly improved with marked increases in fish diversity metrics, where hydrochemical factors and species diversity exhibited the highest sensitivity to connectivity changes; (2) following restoration, the initially barrier-fragmented river segments (upstream, middle, downstream) exhibited significantly decreased differences in aquatic habitat and fish diversity, demonstrating progressive homogenization across reaches; (3) hydrological factors exerted stronger positive effects on fish diversity than hydrochemical factors did, particularly enhancing species diversity, with a significant positive synergistic effect observed between species diversity and functional diversity. …”
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MCM4 as Potential Metastatic Biomarker in Lung Adenocarcinoma by Hung-Chih Lai, Ju-Fang Liu, Tsung-Ming Chang, Thai-Yen Ling

“…<b>Methods:</b> We analyzed four GEO microarray datasets (GSE32863, GSE27262, GSE40275, and GSE33356) and TCGA data to identify differentially expressed genes (DEGs) in LUAD. Functional enrichment of DEGs was analyzed using Gene Ontology, Kyoto Encyclopedia of Genes and Genomes analysis, and a Cancer Hallmark Enrichment Plot. …”
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The Efficacy and Brain Network Mechanism of Acupuncture for Knee Osteoarthritis: A Study Protocol for Randomized Controlled Neuroimaging Trial by Sun YY, Wang ML, Zhao RH, Hao MY, Song S, Zhou Y, Zhang N

“…The primary efficacy indicator will be the change in NRS score after four weeks of treatment, with secondary outcomes including WOMAC, STAI, and safety assessments. fMRI observations will employ independent component analysis, brain network construction, and functional connectivity, complemented by Pearson correlation analysis to explore the relationship between brain responses and clinical improvements.Conclusion: This study will initially uncover how acupuncture intervention for chronic KOA pain centrally regulates and exerts therapeutic effects through the modulation of abnormal brain network functional connectivity patterns, with a demonstrated long-term effect.Ethics and Dissemination: This study has been approved by the ethics committee of Shandong University of Traditional Chinese Medicine Affiliated Hospital ((2024) Lunshen No. (028) - KY).Clinical Trial Registration: This study has been approved by registered in the Chinese Clinical Trial Registry (ChiCTR2400083695).Keywords: acupuncture, knee osteoarthritis, neuroimaging, RCT, protocol…”
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Transcriptome and Physio-Biochemical Profiling Reveals Differentially Expressed Genes in Seedlings from Aerial and Subterranean Seeds Subjected to Drought Stress in <i>Amphicarpaea... by Jiancheng Kou, Yue Su, Tianyu Lei, Siqi Hou, Jiali Tian, Minglong Li, Shuzhen Zhang, Xiaodong Ding, Qiang Li, Jialei Xiao

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High-intensity ethanol binge drinking accentuates bone damage in induced apical periodontitis in rats by José Mário Matos-Sousa, Deiweson Souza-Monteiro, Vinicius Ruan Neves dos Santos, Maria Karolina Martins Ferreira, Deborah Ribeiro Frazão, Victória Santos Chemelo, Leonardo de Oliveira Bittencourt, João Daniel Mendonça de Moura, Cristiane do Socorro Ferraz Maia, Fabrício Mezzomo Collares, Luanna de Melo Pereira Fernandes, Rafael Rodrigues Lima

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Bisoprolol for patients with chronic obstructive pulmonary disease at high risk of exacerbation: the BICS RCT by Graham Devereux, Seonaidh Cotton, Mintu Nath, Nicola McMeekin, Karen Campbell, Rekha Chaudhuri, Gourab Choudhury, Anthony De Soyza, Shona Fielding, Simon Gompertz, John Haughney, Amanda Lee, Graeme MacLennan, Alyn Morice, John Norrie, David Price, Philip Short, Jorgen Vestbo, Paul Walker, Jadwiga Wedzicha, Andrew Wilson, Olivia Wu, Brian Lipworth

“…Total number of major adverse cardiovascular events. Lung function (NB, during the COVID-19 pandemic, lung function could not be assessed in participants). …”
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Establishing a Collaborative Genomic Repository for Adult Burn Survivors: A Burn Model System Feasibility Study by Stephen Sibbett, Jamie Oh, Gretchen Carrougher, Lara Muffley, Nathaniel Ashford, Maiya Pacleb, Samuel Mandell, Jeffrey Schneider, Steven Wolf, Barclay Stewart, Nicole S. Gibran

“…We found no association between COMT variants and functional outcomes, likely due to the inadequate sample size. …”
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Perancangan dan Implementasi Sistem Informasi Deteksi Kesesuaian Pemanfaatan Ruang Berbasis Web dengan Fitur Geo-Intersection Pada POSTGIS by Issa Arwani, Widhy Hayuhardhika Nugraha Putra, Ghazian Hamdi, Tsania Dzulkarnain

“…Sedangkan analisis KKPR diproses secara otomatis langsung di database PostGIS dengan memanfaatkan fitur Geo-Intersection. …”
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Development and validation of a CT-based multi-omics nomogram for predicting hospital discharge outcomes following mechanical thrombectomy by Feifan Liu, Jiayi Hong, Yuhan Chen, Huan Liu, Yue Wang, Lijian Su, Sheng Hu, Jingjing Fu

“…A support vector machine (SVM)-based nomogram integrating clinical, radiomics, and DTL features was developed to predict functional outcomes at discharge. Its performance was evaluated based on accuracy, sensitivity, specificity, receiver operating characteristic (ROC) curve and area under the curve (AUC) analysis, decision curve analysis (DCA), and the DeLong test.ResultsThe nomogram achieved AUCs of 0.995 (95% CI: 0.989–1.000) in training, 0.959 (95% CI: 0.910–1.000) in validation, and 0.894 (95% CI: 0.807–0.981) in test cohorts. …”
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Value-legal and semantic characteristics of an officer's operational-search activities by Petr Y. Naumov, Sergey I. Zakhartsev

“…A systems approach in all its conceptual aspects (subject, functional and historical) was used as the research methodology. …”
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Temperature-driven metabolic shifts in duck egg components during early embryogenesis: from diapause to active developmental phase by Zekuan Zuo, Qian Chen, Chengxin Hu, Qian Tang, Chenling Song, Hehe Liu

“…Using 12 duck eggs divided equally into experimental and control groups, we conducted untargeted metabolomics to profile metabolic dynamics during the 48-h diapause-to-embryogenesis transition across pre- and post-incubation phases. Differential metabolite analysis in yolk and albumen was integrated with KEGG pathway enrichment to identify functional shifts linked to embryonic reactivation. …”
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Genome-wide exonic small interference RNA-mediated gene silencing regulates sexual reproduction in the homothallic fungus Fusarium graminearum. by Hokyoung Son, Ae Ran Park, Jae Yun Lim, Chanseok Shin, Yin-Won Lee

“…Various ascomycete fungi possess sex-specific molecular mechanisms, such as repeat-induced point mutations, meiotic silencing by unpaired DNA, and unusual adenosine-to-inosine RNA editing, for genome defense or gene regulation. Using a combined analysis of functional genetics and deep sequencing of small noncoding RNA (sRNA), mRNA, and the degradome, we found that the sex-specifically induced exonic small interference RNA (ex-siRNA)-mediated RNA interference (RNAi) mechanism has an important role in fine-tuning the transcriptome during ascospore formation in the head blight fungus Fusarium graminearum. …”
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The The Role of miRNA-150 in Newly Diagnosed and Treated Patients with Acute Myeloid Leukemia by Rasha D. Kalf, Yaseen I. Mamoori

“…The small non-coding RNA molecule known as microRNA-150 (miR-150) is involved in the control of gene expression in several biological functions, including hematopoiesis, the process that creates new blood cells. miR-150 has been studied in relation to acute AML for its possible functions in leukemogenesis and normal hematopoiesis. …”
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