F-box/LRR-repeat protein 12 reorchestrated microglia to inhibit scarring and achieve adult spinal cord injury repair by Xu Xu, Feng Gao, Qixin Chen, Bairu Chen, Wenyu Liang, Runzhi Huang, Yuchen Liu, Zhibo Liu, Yanjing Zhu, Gufa Lin, Bei Ma, Letao Yang, Shaorong Gao, Rongrong Zhu, Liming Cheng

“…Importantly, axons grew through the epicenter and reached a length of more than 2.4 mm 56 days post-SCI, significantly improving motor function and reconstructing the neural circuit. …”
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LKB1 dictates sensitivity to immunotherapy through Skp2-mediated ubiquitination of PD-L1 protein in non-small cell lung cancer by Wei Liu, Dong Wang, Qing Miao, Peilin Chen, Hongbing Liu, Jiawen Lv, Jie Yin, Jian Feng, Yong Song, Tangfeng Lv, Mingxiang Ye, Wenjie Yan, Liting Lv, Sutong Zhan

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Dynamic regulation of Rgs16 and its correlation with Neuregulin1 expression in acute and chronic nerve injury by Marina García-Bejarano, Marina García-Bejarano, Marina García-Bejarano, Riccardo Aucello, Riccardo Aucello, Federica Zen, Federica Zen, Marwa El Soury, Marwa El Soury, Francesca Cordero, Jesús M. de la Fuente, Isabelle Perroteau, Giulia Ronchi, Giulia Ronchi, Giovanna Gambarotta, Giovanna Gambarotta

“…Further investigations are needed to clarify RGS16 function, which could pave the way for novel therapeutic strategies to enhance nerve regeneration and alleviate neuropathic pain.…”
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COVID-19 in discharged patients with diabetes and chronic kidney disease: one-year follow-up and evaluation by Enrong Ran, Enrong Ran, Yutong Zou, Chuanyi Zhao, Kai Liu, Jiamin Yuan, Wenjie Yang, Lijun Zhao, Qing Yang, Jia Yang, Xuegui Ju, Linli Cai, Yanlin Lang, Xingyuan Li, Ke Liu, Fang Liu, Fang Liu

“…Cox proportional hazards regression indicated that sepsis and mechanical ventilation were major risk factors for post-discharge all-cause mortality. Logistic regression identified baseline eGFR < 60 mL/min/1.73 m² as an independent risk factor for rapid CKD progression.ConclusionsDuring the one-year follow-up period, we observed that patients with diabetes and CKD exhibited higher all-cause mortality and experienced rapid deterioration of kidney function after acute infection with COVID-19. …”
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Effectiveness of different physical activity programs in improving older adults’ physical capacities: a randomized controlled trial by Carolina A. Cabo, Carolina A. Cabo, Carolina A. Cabo, Carolina A. Cabo, Víctor Hernández-Beltrán, Orlando Fernandes, Orlando Fernandes, Cláudia Mendes, Cláudia Mendes, Cláudia Mendes, José M. Gamonales, José M. Gamonales, José M. Gamonales, Mário C. Espada, Mário C. Espada, Mário C. Espada, Mário C. Espada, Mário C. Espada, José A. Parraca, José A. Parraca

“…In contrast, the Control and Pilates Groups did not exhibit significant improvements in any of the assessed variables. The analysis of the moment*group interaction effect revealed significant differences among the groups, except for the Timed Up and Go (TUG) test.ConclusionIn conclusion, sensorimotor and aquatic training significantly improved physical function, especially balance, strength, and mobility, in older people.…”
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Ashwagandha (Withania somnifera (L.) Dunal) for promoting recovery in long covid: protocol for a randomised placebo-controlled clinical trial (APRIL Trial) by Kamlesh Khunti, Shailen Sutaria, Poppy Alice Carson Mallinson, Sanjay Kinra, Rohini Mathur, Anoop SV Shah, Tim Clayton, Judith Lieber, Alexander Perkins, Shereen Allaham, Nick Birk, Lily Hopkins, Manisha Joshi, Mahesh Mathpathi, Arandeep Dhillon, Sidra S Beg, Archie Khan, Vanessa TW Kam, Galib R, S Rajagopala, Amarjeet Bhamra, Geetha Krishnan G Pillai, Tanuja Nesari

“…The primary outcome of the Post-COVID Functional Status Scale score at 3 months will be assessed by baseline-adjusted ordinal logistic regression, according to a pre-published statistical analysis plan. …”
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Early Epcoritamab Administration Revives CAR‐T Cells in Relapsed/Refractory B‐Cell Lymphomas by Kensuke Yanashima, Yoshiki Furukawa, Midori Ishii, Shintaro Kinoshita, Yasuharu Hamano, Naoki Watanabe, Yutaka Tsukune, Hajime Yasuda, Jun Ando, Miki Ando

“…Methods Peripheral blood CAR‐T kinetics and functional analysis in vivo were carried out pre‐ and post‐epcoritamab infusion in B‐cell lymphoma patients relapsing after CAR‐T therapy. …”
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Variable-Rate Incremental-Redundancy HARQ for Finite Blocklengths by Yu Fu, Angel Lozano, Hongwen Yang

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Effect of Surface Modification for Efficient Electroplating of 3D-Printed Components by Dagmar Klichová, Hana Krupová, Jakub Měsíček, František Botko, Světlana Radchenko

“…Plastic materials represent an affordable alternative, but their surface treatment, in the form of post-coating, achieves properties comparable to those of metal parts while saving expensive metal material. …”
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The lactylation modification of proteins plays a critical role in tumor progression by Dehao Yi, Ke Zhou, Yinlong Pan, Huazhong Cai, Pan Huang, Pan Huang

“…Lactylation modifications have been shown to be a novel type of protein post-translational modifications (PTMs), providing a new perspective for understanding the interaction between cellular metabolic reprogramming and epigenetic regulation. …”
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Sputum microbiota profiles of patients with rifampicin-resistant tuberculosis during the intensive-phase treatment by Xingshan Cai, Yuan Lin, Bitong Wu, Yang Luo, Kun Li

“…Functional analysis showed reduced microbial functions related to pyruvate fermentation and amino acid metabolism in RR-TB patients. …”
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SEC-MX: an approach to systematically study the interplay between protein assembly states and phosphorylation by Ella Doron-Mandel, Benjamin J. Bokor, Yanzhe Ma, Lena A. Street, Lauren C. Tang, Ahmed A. Abdou, Neel H. Shah, George Rosenberger, Marko Jovanovic

“…Abstract A protein’s molecular interactions and post-translational modifications (PTMs), such as phosphorylation, can be co-dependent and reciprocally co-regulate each other. …”
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Relationships Matter Most: A Mixed Methods Study into Meaning in Life in Personality Disorder, Before and After Treatment by Angelien Steen, Pauline Sam, Carmen Schuhmann, Arjan W. Braam

“…The sample included patients with PD (pre-treatment n = 125, post-treatment n = 85) and a control group (n = 69). …”
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Extracting Realistic Pedestrian, Cycling, and Driving Street Networks from OpenStreetMap by J. P. Duque, M. A. Brovelli

“…To address this, we propose a methodology which employs a set of filters and post-processing algorithms in a selective removal process to mitigate such inconsistencies and generate networks that are realistic and usable for various applications like routing and analysis. …”
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The Efficiency of Government Control and Civil Service in the Public Health Service by G.  A. Borshchevskiy

“…It was proved that during post-Soviet years the real development in healthcare did not occur. …”
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A comprehensive genome-wide study on tissue-specific and abiotic stress-specific miRNAs in Triticum aestivum. by Ritu Pandey, Gopal Joshi, Ankur R Bhardwaj, Manu Agarwal, Surekha Katiyar-Agarwal

“…Digital gene expression analysis revealed that 257 miRNAs exhibited tissue-specific expression and 74 were associated with abiotic stresses. …”
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EVALUATION OF THE PSYCHOSOCIAL IMPACT OF DENTAL AESTHETICS BY SOCIODEMOGRAPHICS AND MALOCCLUSIONS by Kalender Muhammed Emin, Ucan Yarkac Fatma, Emiroglu Yunus

“…These results align with previous studies but expand understanding by including a wider age range and malocclusion analysis.Conclusion: Dental aesthetics deeply influence self-confidence and social interactions, emphasizing the importance of addressing these concerns for both functional and psychological reasons. …”
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A Study on the Aesthetic Tendency of the YZ Generation in China Toward the Façade Design of Coffee Shop Buildings by Shaochen Wang, Yang Song

“…The results of the classification summary and post hoc multiple comparison analysis showed that façade design was considered an important factor affecting their choices, and if the façade design met their aesthetic preferences, they would visit the store again. …”
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Correlation of intensity of physical activity and subjective health status of adults working in selected institutions, Bangaluru, India by Dekey Yanzom et al.

“…Participants had the highest mean score in social functioning, followed by emotional well-being, and most subjects (92.7%) reported having mild health complaints. …”

TRANSFORMATION OF THE CONCEPT "SUBJECT" IN THE CLINICAL DISCOURSE OF PHILOSOPHICAL ANTHROPOLOGY by V. M. Skyrtach

“…The logic of the research coincides with the paradigmatic understanding of the subject’s transformations and suggests a transition from diagnostic strategies of the analysis of individual being as the basis of the pathological nature of the subject to the study of therapeutic models of communication as the determinants of pathology and, finally, to the analytics of the subject in the horizon of polysubject sociality.Originality of the work consists in disclosing the basic anthropological models of the subject, corresponding to the functions of diagnosis and therapy. …”
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