DCP1A, a MEK substrate, regulates the self-renewal and differentiation of mouse embryonic stem cells by Jiayu Yu, Nannan Zhao, Yuying Wang, Nan Ding, Zhenchang Guo, Zichan He, Qingye Zhang, Jingai Zhang, Xiaoqiong Yang, Ming Zhang, Xiaoling Du, Kai Zhang, Lingyi Chen

“…To understand the mechanism of MEK in pluripotency maintenance, we first demonstrated that MEK regulates gene expression at post-transcriptional steps. Consistently, many of the 66 MEK substrates identified by quantitative phosphoproteomics analysis are involved in RNA processing. …”
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Effectiveness of unilateral lower-limb exoskeleton robot on balance and gait recovery and neuroplasticity in patients with subacute stroke: a randomized controlled trial by Congcong Huo, Guangjian Shao, Tiandi Chen, Wenhao Li, Jue Wang, Hui Xie, Yan Wang, Zengyong Li, Pengyuan Zheng, Liguo Li, Luya Li

“…The increased cortical response related to the ipsilesional motor areas and their related functional network is crucial in the rehabilitation of lower limb gait in post-stroke patients.…”
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The effect of dexmedetomidine on acute kidney injury after elective major abdominal surgery : a retrospective single-center propensity score matched study by Haibei Liu, Rong Luo, Liu Qian, Yujun Zhang, Wensheng Zhang, Juan Tan, Ling Ye

“…Furthermore, a subgroup analysis was conducted based on the infusion rate and the use of a loading dose to explore the effects of different methods of dexmedetomidine administration on AKI. …”
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Alginate–Poly[2-(methacryloyloxy)ethyl]trimethylammonium Chloride (PMETAC) Immunoisolating Capsules Prolong the Viability of Pancreatic Islets In Vivo by Polina Ermakova, Ekaterina Vasilchikova, Arseniy Potapov, Maxim Baten’kin, Liya Lugovaya, Alexandra Bogomolova, Julia Tselousova, Alexey Konev, Natalia Anisimova, Alena Egoshina, Mariya Zakharina, Nasipbek Naraliev, Denis Kuchin, Vladimir Zagainov, Sergey Chesnokov, Aleksandra Kashina, Elena Zagaynova

“…This study further probes the capsules in vivo, focusing on the functional activity of the encapsulated islets post-transplantation, their viability extension, and the assessment of the immunoprotective, antifibrotic properties, and biostability of the capsules. …”
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Genetic Parameters, Linear Associations, and Genome-Wide Association Study for Endotoxin-Induced Cortisol Response in <i>Holstein heifers</i> by Bruno A. Galindo, Umesh K. Shandilya, Ankita Sharma, Flavio S. Schenkel, Angela Canovas, Bonnie A. Mallard, Niel A. Karrow

“…In heifers, an LPS challenge induces a dynamic stress response, marked by elevated cortisol levels, increased body temperature, and altered immune function. Research indicates that LPS administration leads to a significant rise in cortisol post-challenge. …”
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Web-based early intervention for children with motor difficulties aged 3–8 years old using multimodal rehabilitation (WECARE): protocol of a patient-centred pragmatic randomised tr... by Thomas G Poder, Desiree B Maltais, Tibor Schuster, Marie-Claude Battista, Michelle Phoenix, Jean-Patrice Baillargeon, Chantal Camden, Jill G Zwicker, Melanie Morin, Melanie Couture, Mathieu Goyette, Gabrielle Pratte, Karen Hurtubise, Tram Nguyen, Jade Berbari, Michel Tousignant

“…Participants will be asked to re-evaluate the child’s COPM performance goals every 3 months up to 1 year post allocation. The COPM results will be analysed using a mixed Poisson regression model. …”
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Baseline serum EV-miR-1-3p as a protective factor and biomarker for hepatocellular carcinoma development after HCV eradication by Wei Teng, Wei-Ting Ku, Po-Ting Lin, Guan-Ting Chen, LiChieh Julie Chu, Hsuan Liu, Yung-Chang Lin, Chun-Yen Lin

“…Reliable biomarkers for predicting the post-SVR HCC risk are lacking. This study aimed to identify baseline serum extracellular vesicle microRNAs (EV-miRNAs) associated with HCC development following SVR. …”
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FTO controls CD8+ T cell survival and effector response by modulating m6A methylation of Fas by Lina Sun, Tianzhe Zhang, Yao Ge, Zhihong Yao, Yanhong Su, Qianhao Wang, Yang Chen, Boxiao He, Renyi Ding, Cangang Zhang, Linbo Lan, Ruonan Liu, Huanxin Ping, Dan Zhang, Lin Shi, Xiaobo Zhou, Xiaoxuan Jia, Chenming Sun, Lingli Liang, Lianjun Zhang, Baojun Zhang

“…Our findings delineate a novel epigenetic regulatory mechanism of FTO-mediated m6A modification in supporting CD8+ T cell survival and effector responses, providing new insights into understanding the post-transcriptional regulation in CD8+ T cell immunological functions and the potential therapeutic intervention.…”
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Efficacy of corticosteroids addition to multimodal cocktail periarticular injection in total knee arthroplasty with hemophilic arthropathy by Hai Su, Shenxu Yu, Lei Chen, Haojing Zhou, Yichen Gong, Hua Huang, Shuaijie Lv, Peijian Tong, Xun Liu, Jun Ying

“…Both groups improved knee joint function and reduced post-operative pain at the last follow-up. …”
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TRANSLATION STRATEGIES IN ENGLISH-UKRAINIAN RENDERING OF DUAL-NUMBER QUANTIFI by Oleksandr O. Lytvynov

“…As a result, based on dictionary entries’ analysis, the main functional-semantic classes of the quantifiers have been found to be the determiner, pronoun, conjunction and pronominal adverb. …”
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Measuring the impact of community-based interventions on type 2 diabetes control during the COVID-19 pandemic in Cape Town – A mixed methods study by Neal J. David, Graham Bresick, Natasha Moodaley, Klaus B. von Pressentin

“…The mean glycaemic control was suboptimal both at baseline and post-lockdown in both groups. Interviews with 83 study patients confirmed the acceptability of the home delivery intervention. …”
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Enhancing the Energy Content of Melawan Coal through H₂SO₄ and NaOH Demineralization by Aliyu Buba Ngulde, Wan Azlina Wan Ab Karim Ghani, Nazmi Mat Nawi, Umer Rashid, Kiman Silas

“…According to FTIR analysis, the presence of carbonyl groups can affect the performance of coal in processes such as gasification, pyrolysis, or combustion, making it a key functional group of interest for evaluating post-treatment coal properties. …”
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Teaching Modeling in Introductory Statistics: A Comparison of Formula and Tidyverse Syntaxes by Amelia McNamara

“…The tidyverse labs exposed students to more distinct R functions, but reused functions more frequently. Both labs relied on a relatively small vocabulary of functions, which can provide a starting point for instructors interested in teaching introductory statistics in R. …”
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Probiotic treatment induces sex-dependent neuroprotection and gut microbiome shifts after traumatic brain injury by Morgan Holcomb, Austin G. Marshall, Hannah Flinn, Mariana Lozano-Cavazos, Sirena Soriano, Fernando Gomez-Pinilla, Todd J. Treangen, Sonia Villapol

“…Immunohistochemical, in situ hybridization, and histological analyses were performed to assess neuroinflammation post-TBI, while behavioral assessments were conducted to evaluate sensorimotor and cognitive functions. …”
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UltraTape and sutures combination versus conventional sutures in arthroscopic rotator cuff repair: a 6-month retrospective matched cohort study by Ala’ Hawa, James Bilbrough, Christyon Hayek, Mina Shenouda, George A. C. Murrell

“…The aim of this study was to determine if the biomechanical advantage of UltraTape would translate into a better repair integrity and higher functional outcome in the clinical setting. Methods Retrospective analysis of 81 matched consecutive patients (suture group, n = 53; tape group, n = 28) with a cuff tear size greater than 1.5*1 cm² (antero-posterior * medio-lateral diameters) repaired by a single senior surgeon. …”
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Early rehabilitation and improved outcomes in patients with status epilepticus: Evidence from cases presenting to the emergency department by Hidetaka Onda, Shoji Yokobori

“…Intensive care unit‐acquired weakness and post‐intensive care syndrome are significant issues in survivors of SE. …”
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Heart Rate Variability and Autonomic Dysfunction After Stroke: Prognostic Markers for Recovery by Sara Lago, Toon T. de Beukelaar, Ilaria Casetta, Giorgio Arcara, Dante Mantini

“…Evidence shows that reduced HRV is associated with poorer functional outcomes, higher mortality, and increased risk of complications post-stroke. …”
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Exploring molecular and modular insights into space ionizing radiation effects through heterogeneous gene regulatory networks by Mengqin Yuan, Tao Zhang, Haizhou Liu, Min Long, Quan Wang, Wei Jiang

“…Functional enrichment analysis revealed associations with processes such as cell cycle regulation, cytidine deamination, cell differentiation, viral carcinogenesis, and apoptosis. …”
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Sarcopenia in Patients with Chronic Thromboembolic Pulmonary Hypertension by Steven Hopkins, Jillian Hall, Hollie Saunders, Riyaz Bashir, Vladimir Lakhter, Anjali Vaidya, Ahmed Sadek, Paul Forfia, Estefania Oliveros

“…Background: Sarcopenia, or loss of skeletal muscle mass, has been associated with poor outcomes (e.g., functional decline, increased mortality, and low quality of life), but its role in CTEPH remains unclear. …”
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Consumption of only wild foods induces large scale, partially persistent alterations to the gut microbiome by Simone Rampelli, Diederik Pomstra, Monica Barone, Marco Fabbrini, Silvia Turroni, Marco Candela, Amanda G. Henry

“…There is a clear successional shift from the pre-, during- and post-wild-food-only diet. This analysis highlighted structural and functional shifts in microbial interactions, underscoring diet’s role in shaping the gut ecosystem.…”
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