INSTITUTIONAL FACTORS OF THE IMPLEMENTATION OF INNOVATIVE RENEWABLE ENERGY PROJECTS IN EXTREME СONDITIONS by Леся Гнилянська, Нестор Шпак, Олексій Побурко

“…Based on a comparative analysis of international experience, in particular of countries that implemented renewable energy in post-conflict recovery or during crisis situations (for example, Denmark, Germany, Ukraine), key parameters of institutional capacity have been identified. …”
Get full text

Triglyceride-glucose index as a predictor of one-year mortality in non-diabetic acute ischemic stroke by Shengyuan Wang, Xianjia Ning, Xianjia Ning, Xianjia Ning, Xianjia Ning, Jun Tu, Jun Tu, Jun Tu, Jinghua Wang, Jinghua Wang, Jinghua Wang, Jinghua Wang, Yu Zhao

Get full text

Analytical Solution for the Time Fractional BBM-Burger Equation by Using Modified Residual Power Series Method by Jianke Zhang, Zhirou Wei, Longquan Yong, Yuelei Xiao

Get full text

On some conceptual sources of the wealth maximization theory by Richard Posner: Adam Smith and Jeremy Bentham by V. S. Dorokhin, A. V. Polyakov

“…Objective: to identify some aspects of the historical genesis of the ideas of wealth maximization theory by Richard AllenPosner - one of the main representatives of the Chicago school of economic analysis of law.Methods: post-classical approach to the cognition of social phenomena, which allows analyzing them in their historical development and functioning as the complex of objective and subjective factors; portrait method; comparative legal and formal logical analysis.Results: the wealth maximization theory by R. …”
Get full text

Predictive value of pan-immune-inflammation value in the prognosis of adults with status epilepticus: a retrospective study by Jie Fu, Yifei Chu, Chenxin Zhao, Lilei Peng

“…ObjectiveTo investigate the predictive capacity of the pan-immune-inflammation value (PIV) for functional outcomes in patients with status epilepticus (SE).MethodsIn this study, we investigated and confirmed the prognostic significance of PIV in adult patients with SE. …”
Get full text

Landscape of the Peripheral Immune Response Induced by Intraoperative Radiotherapy Combined with Surgery in Early Breast Cancer Patients by Danian Dai, Xuerui Li, Hongkai Zhuang, Yun Ling, Lezi Chen, Cheng Long, Jinhui Zhang, Yunjie Wang, Yuehua Li, Hailin Tang, Bo Chen

“…IORT+Surgery demonstrated the ability to partially suppress the anti‐tumor effects of neutrophils. Flow cytometry analysis and co‐culture experiments are utilized to delve deeper into the functional alterations in T cells. …”
Get full text

Application of the Fitness and Nutrition Program for Seniors (FANS) to improve Physical Activity and Kinanthropometric Measures among Community-Dwelling Older Adults living with Fr... by Pei-Shan Li, Chia-Jung Hsieh, Nae-Fang Miao, Chuan-Hsiu Tsai, Chieh-Yu Liu, Hung-Ru Lin, Shu-Fang Vivienne Wu, Jordan Koh

Get full text

Investigating the risks of late preterm and term neonatal morbidity across clinical subtypes of intrahepatic cholestasis of pregnancy by Wei-Zhen Tang, Wei-Zhen Tang, Yi-Fan Zhao, Lan Wang, Qin-Yu Cai, Qin-Yu Cai, Wei-Ze Xu, Li Wen, Xue-Bing Chen, Ting-He Sheng, Ting-He Sheng, Tian-Qi Fan, Tai-Hang Liu, Rong Li, Shang-Jing Liu

“…The study also highlighted that late preterm or post-term delivery in the ICP-M patients exacerbates NICU risk.ConclusionWomen with ICP-M experience elevated perinatal risks, including a higher risk of coexisting GDM, as well as increased risks of preterm birth and NICU admissions. …”
Get full text

The m6A modification regulates the composition of myofiber types in chicken skeletal muscle by Yanju Shan, Yifan Liu, Ming Zhang, Lichuan Pang, Gaige Ji, Xiaojun Ju, Yunjie Tu, Jingting Shu

“…As a widespread epigenetic RNA modification, N6-methyladenosine (m6A) plays essential regulatory roles in multiple biological processes. However, its function in maintaining and modulating myofiber-type properties remains largely unknown. …”
Get full text

Real-world outcomes of spinal muscular atrophy treatment with onasemnogene abeparvovec in Croatia: a comprehensive case series and literature review by Ivan Lehman, Ivan Lehman, Matija Matošević, Lovro Lamot, Lovro Lamot, Branka Bunoza, Branka Bunoza

“…Onasemnogene abeparvovec-xioi, an adeno-associated viral vector-based gene therapy delivering a functional copy of the SMN1 gene, has shown significant efficacy in improving motor function and survival rates. …”
Get full text

The de novo design and synthesis of yeast chromosome XIII facilitates investigations on aging by Chun Zhou, Yun Wang, Yikun Huang, Yongpan An, Xian Fu, Daqian Yang, Yilin Wang, Jintao Zhang, Leslie A. Mitchell, Joel S. Bader, Yizhi Cai, Junbiao Dai, Jef D. Boeke, Zhiming Cai, Zhengwei Xie, Yue Shen, Weiren Huang

“…Our findings underscore the potential of synthetic yeasts in unveiling the function of aging-related genes.…”
Get full text

Preventing the transition from acute to chronic low back pain using home-based neuromodulation: protocol for a randomised, controlled study by Luke C Jenkins, James McAuley, Aidan Cashin, Tasha R Stanton, Amitabh Gupta, Rocco Cavaleri, Simon Summers, Keeley R McNally, Ariane Y Suhood, Daniel Thomson, Ghufran Alhassani

“…Participants will attend five laboratory sessions (pre-intervention baseline; at intervention completion; 4 weeks, 8 weeks and 12 weeks post-completion of intervention) where measures of pain processing and disability will be collected. …”
Get full text

Effect of opioid-free anaesthesia on postoperative delirium in elderly patients undergoing gastrointestinal surgery: study protocol for a single-centre, prospective, randomized con... by Yuehan Du, Mengjie Liu, Xiaoling Yang, Jianbo Wu, Xiaojun Gao, Qiuyue Liu, Lina Chen, Xiaxuan Sun, Min Zhang, Yongtao Sun

“…This study aims to investigate the effects of OFA on the development of POD in elderly patients following gastrointestinal surgery. Methods and analysis This single-centre, prospective, randomized controlled trial will be conducted at the First Affiliated Hospital of Shandong First Medical University, China. …”
Get full text

Impact of short-term housing temperature alteration on metabolic parameters and adipose tissue in female mice by Henry A. Paz, Henry A. Paz, C. G. Shashank, C. G. Shashank, Lasya Buddha, Tian Lam, Taylor Zhang, Ying Zhong, James D. Sikes, Craig Porter, Reid D. Landes, Roy Morello, Umesh D. Wankhade, Umesh D. Wankhade

“…Adipose tissue showed smaller adipocytes in iWAT and increased vascularity in BAT, though no persistent changes in thermogenic gene expression or glucose homeostasis were observed. Proteomic analysis of iWAT identified 38 differentially expressed proteins, with enrichment of pathways related to mitochondrial function and mTOR signaling.DiscussionShort-term cold exposure induced lasting histological and proteomic changes in iWAT and BAT without sustained effects on energy metabolism, likely due to reversion to RT and limited sample size.ConclusionBrief temperature manipulation around pregnancy can durably alter maternal adipose tissue architecture and molecular signatures, underscoring ambient temperature as an important modulator of maternal metabolic adaptation.…”
Get full text

Metabolic stress and early cell death in photoreceptor precursor cells following retinal transplantation by Raghavi Sudharsan, Natalia Dolgova, Jennifer Kwok, Alexa Gray, Yu Sato, Agustin Luz Madrigal, Praveen Joseph Susaimanickam, Emil Kriukov, Petr Baranov, John H. Wolfe, Gustavo D. Aguirre, David M. Gamm, William A. Beltran

“…Results Despite systemic immunosuppression, extensive early loss of human PRPCs occurred within the first week following xenotransplantation into both normal and degenerated canine retinas, suggesting that factors beyond immune activation contribute to donor cell loss. Transcriptomic analysis identified metabolic stress as a key driver of early donor cell death, characterized by dysregulation of mitochondrial function and oxidative phosphorylation pathways. …”
Get full text

Sirtuin 1 expression in elderly patients with type 2 diabetes mellitus by Mohamed M. M. Hassaan, Imam M. Esmayel, Mayada M. Mousa, Samia Hussein, Ahmed K. Y. Alkolaly, Batoul A. Hegazy, Rodalia M. Makhlouf

“…SIRT3 is a mitochondrial enzyme that regulates mitochondrial functions, including ATP synthesis, reactive oxygen species production, fatty acid oxidation, ketone metabolism, and cellular death. …”
Get full text

Effect of diabetes mellitus on spinal cord high signal relief after anterior cervical spine surgery in patients with cervical spondylotic myelopathy by Zichuan Wu, Xuhong Zhang, Hanlin Song, Aochen Xu, Baifeng Sun, Chen Xu, Min Qi, Yang Liu

“…Results The findings from this investigation underscore the critical role of preoperative glycated hemoglobin (HbA1c) levels in determining the postoperative outcomes in patients with cervical spondylotic myelopathy (CSM) who also have diabetes mellitus. Our analysis reveals that although preoperative HbA1c levels did not significantly impact outcomes at six months post-surgery (Table2 and Table4), maintaining low HbA1c levels was associated with considerable improvements in both spinal cord high signal (HCS) and neurological function at two years postoperatively (Table3 and Table5). …”
Get full text

Comparison of the proteomic landscape in experimental ischemia reperfusion with versus without ischemic preconditioning by Yalda Kakaei, Shafaat Hussain, Ahmed Elmahdy, Evelin Berger, Aaron Shekka Espinosa, Valentyna Sevastianova, Zahra Sheybani, Amin Al-Awar, Mana Kalani, Sandeep Jha, Ermir Zulfaj, Amirali Nejat, Abhishek Jha, Tetiana Pylova, Maryna Krasnikova, Erik Axel Andersson, Vagner Ramon Rodrigues Silva, Elmir Omerovic, Björn Redfors

“…Myocardial samples were collected at early (T1) and 4-hour post-reperfusion (T2) time points for proteomic analysis. …”
Get full text

Verification of Lactobacillus brevis tolerance to simulated gastric juice and the potential effects of postbiotic gamma-aminobutyric acid in streptozotocin-induced diabetic mice by Amro Abdelazez, Heba Abdelmotaal, Smith Etareri Evivie, Maha Bikheet, Rokayya Sami, Hassan Mohamed, Xiangchen Meng

“…Based on the blood plasma analysis, L. brevis strains improved good cholesterol properties, liver and kidney functions, where most of these parameters fall within the average the reference range and prevent the development of symptoms of type 1 diabetes in vivo. …”
Get full text

Effects of High-Resolution Natural Sound with Inaudible High-Frequency Components on Healing, Symptoms, and Sleep Satisfaction in Terminally Ill Cancer Patients by Yasutaka Shimotsuura, Keisuke Ishizuka, Takashi Kawaguchi, Kazue Umetsu, Mariko Harada, Yujiro Inoue, Emi Kubo, Kazuhiro Kosugi, Takashi Igarashi, Seiya Enomoto, Hidehiko Taniyama, Tetsuo Iwata, Takuhiro Yamaguchi, Yoshihisa Matsumoto, Tomofumi Miura

“…Objectives: This study aimed to assess the effects of high-resolution natural sound with inaudible high-frequency components (HNIH) on healing, symptoms, sleep satisfaction, and autonomic nerve function among terminally ill cancer patients. Methods: We conducted a single-arm, open-label study of 4-hour HNIH for 20 terminally ill cancer patients. …”
Get full text