Combined Utility of Speckle Tracking Echocardiography and Cardiac Biomarkers for Early Detection of Anthracycline-Induced Cardiotoxicity in Pediatric Oncology Patients by Cristiana Stolojanu, Ruxandra Steflea, Andrada Mara Micsescu-Olah, Ioana Alexandra, Anca Popoiu, Gabriela Doros

“…Assessments were performed at baseline and at 3, 6, and 12 months post-therapy initiation. Results: A total of 28.3% of patients developed cardiotoxicity based on the LVEF decrease. …”
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Evaluation of Immune Responses to Tdap Booster During Pregnancy in Women Who Received Whole Cell or Acellular Pertussis Vaccines During Childhood by Jesse M. Hall, Kyle J. Caution, Kia J.A. Holt, Yash A. Gupta, Myra Guo, Umul Q. Mir, Tami H. Skoff, Susan Hariri, Xueliang Pan, Brett Worly, Purnima Dubey

“…All pertussis and non-pertussis specific serum antibody levels increased post-Tdap booster in aPV- and wPV-primed groups. …”
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Urinary NephroCheck® test, as a marker of subclinical postoperative AKI, correlates with long-term GFR decline in patients undergoing partial nephrectomy: a prospective bicentric o... by Marco Allinovi, Margarete Teresa Walach, Micaela Anna Casiraghi, Marc Weidenbusch, Samantha Innocenti, Lorenzo Tofani, Laura Paparella, Alessandra Fanelli, Gianluca Villa, Philipp Nuhn

“…Samples were collected pre- and post-operatively; renal function was re-assessed up to 24 months. …”
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Lower expression of miR-218 in human breast cancer is associated with lymph node metastases, higher grades, and poorer prognosis by Fereshteh Ahmadinejad, Seyed Javad Mowla, Mohammad-Amin Honardoost, Mostafa Gholami Arjenaki, Mohammad Moazeni-Bistgani, Soleyman Kheiri, Hossein Teimori

“…Finally, to better understand biological function of miR-218 in breast cancer, we performed in silico Gene Ontology and signaling pathway enrichment analysis on miR-218 targetome. …”
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Study of Patients with Polycythemia Vera in JAK2V617F and Mutated and Unmutated Status along with their Anxiety and Worried Thoughts: A Single-center Experience from Eastern India by Rishu Vidhatri, Sandeep Saha, Abhishek Sharma, Shuvra Neel Baul, Tuphan Kanti Dolai

“…Background: Polycythemia vera (PV) is associated with the gain of a function point mutation in Janus 2 tyrosine kinase (JAK-2), leading to an increase in the activity of JAK2V617F. …”
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AERIFY-1/2: two phase 3, randomised, controlled trials of itepekimab in former smokers with moderate-to-severe COPD by Klaus F. Rabe, Fernando J. Martinez, Surya P. Bhatt, Tomotaka Kawayama, Borja G. Cosio, Robert M. Mroz, Maarten M. Boomsma, Helene Goulaouic, Michael C. Nivens, Michel Djandji, Xavier Soler, Ying Liu, Matthew P. Kosloski, Christine R. Xu, Nikhil Amin, Heribert Staudinger, David J. Lederer, Raolat M. Abdulai

“…In a phase 2 study, itepekimab, a human monoclonal antibody against IL-33, reduced exacerbations and improved lung function in a subgroup analysis of former smokers with COPD with an acceptable safety profile. …”
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Genome-wide identification of NHX gene family and effects of salicylic acid in regulating antioxidant activity as well as nutrients deposition under salt stress in three Brassica s... by Rana Muhammad Amir Gulzar, Raheel Munir, Zhang Ren Yi, Nazia Jan, Abdul Rauf, Zohaib Kaleem, Muhammad Haseeb Javaid, Mumtaz Ali Saand, Ali El-Keblawy, Mohamed S. Sheteiwy, Zaid Ulhassan

“…These antiporters play crucial function in various biological processes by regulating Na+ and H+ balance within plant cells. …”
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Outcomes of Early Weightbearing Following Open Reduction and Internal Fixation of Unstable Ankle Fractures in a Geriatric Population by Valerie Carbajal MD, Daniel Choi MD, Brent Kokobun MD, Arash Aminian MD, David Lee MD, Thomas Harris MD

“…There has been a growing trend towards early weightbearing due to its advantages in rehabilitation and return to function. Even so, a survey study revealed that physicians tend to increase the non-weightbearing period for their geriatric population. …”
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Perivascular Lymphocyte Clusters Induced by Gastric Subserous Layer Vaccination Mediate Optimal Immunity against Helicobacter through Facilitating Immune Cell Infiltration and Loca... by Chupeng Hu, Wei Liu, Ningyin Xu, An Huang, Zhiqin Zeng, Shuanghui Luo, Zhenxing Zhang, Menghui Fan, Feng Ye, Tao Xi, Yingying Xing

“…We performed the laparotomy to access the stomach and injected alum-based vaccine into the gastric subserous layer (GSL). At 28 days post vaccination, a parabiosis mouse model along with depletion of anti-CD90.2 antibody was employed to explore the function of perivascular lymphocyte clusters in recall responses. …”
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Exploration of Some Nutrient Absorption–Related Genes and Intestinal Histology in Japanese Quails (Coturnix japonica) Throughout Their Productive Lifespan by Hamid Reza Rafieian‐Naeini, Mahdi Zhandi, Maryam Taghipour‐Shahbandi, Amir Reza Sabzian, Ali Reza Yousefi, Mahboubeh Khajehnabi, Woo Kyun Kim

“…ABSTRACT Background Quail is an efficient poultry species known for many years, and its productivity is highly affected by gastrointestinal function, health, digestion and commensal bacteria. …”
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Bilateral Rectus Sheath Block with Continuous Bupivacaine Infusions After Elective Open Gastrectomy: A Randomized Controlled Trial by Janis Opincans, Igors Ivanovs, Aleksejs Miscuks, Janis Pavulans, Katrina Deja Martinsone, Agris Rudzats, Zurabs Kecbaja, Olegs Gutnikovs, Aleksejs Kaminskis

“…<i>Background and Objectives:</i> Multimodal analgesia has been shown to be effective in facilitating early postoperative gastrointestinal function and rehabilitation in patients undergoing open gastrectomy. …”
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Prediction of 12-month exacerbation-related readmission in hospitalized patients with COPD: a single-center study in China by Cong Zhang, Wenhao Ling, He Pan, Hongxia Tan, Li He

“…Abstract Background Patients with chronic obstructive pulmonary disease (COPD) who are hospitalized multiple times for exacerbations face substantially worse clinical outcomes, including higher mortality, faster lung function decline, and reduced quality of life. Identifying these high-risk individuals is essential for early intervention and improved disease management. …”
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Comparison of the efficacy of laparoscopic primary closure of the common bile duct and T-tube drainage in the treatment of choledocholithiasis in elderly patients by Xiaofan Hua, Gang Wang, Bin Li, Genhai Shen, Wei Liu

“…Results The PC group had shorter operative time, common bile duct suture time, bowel function recovery time, 6-day postoperative VAS, total hospital stay, and postoperative hospital stay compared to the TD group. …”
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Enhancing Predictive Tools for Skeletal Growth and Craniofacial Morphology in Syndromic Craniosynostosis: A Focus on Cranial Base Variables by Lantian Zheng, Norli Anida Abdullah, Norlisah Mohd Ramli, Nur Anisah Mohamed, Mohamad Norikmal Fazli Hisam, Firdaus Hariri

“…<b>Background/Objectives</b>: Patients with syndromic craniosynostosis (SC) pose a significant challenge for post-operational outcomes due to the variability in craniofacial deformities and gain-of-function characteristics. …”
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RISK FACTORS OF MAJOR CARDIOVASCULAR EVENTS IN LONG-TERM PERIOD OF CORONARY BYPASS IN PATIENTS WITH ISCHEMIC HEART DISEASE AND 2ND TYPE DIABETES MELLITUS by A. N. Sumin, N. A. Bezdenezhnykh, A. V. Bezdenezhnykh, S. V. Ivanov, O. L. Barbarash

“…By the results of multifactor analysis as the predictors for MCVE were DM2 (OR 3,30795% CI 1,372-7,968, р=0,007), female gender (OR 2,75295% CI 1,074-7,049, р=0,034), not related to age or renal function. …”
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Influence of puberty stage in immune-inflammatory parameters in well-trained adolescent soccer-players, following 8-weeks of pre-seasonal preparation training by Marios Hadjicharalambous, Eleanna Chalari, Nikolaos Zaras

“…A key limitation of this study is the lack analysis of lymphocyte subpopulations, which could provide a deeper understanding of the cellular effects of training on immune function.…”
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Patient Reported Outcomes from an Open Label, Multi-Center, Retrospective Study of a Biodegradable Graft for Soft Tissue Reconstruction in Patients Suffering from Chronic Lateral A... by Bryan G. Vopat MD, Ryan Scott DPM

“…Surgical repair of the ATFL has relatively high success rates, however post-procedure chronic instability and pain remain a clinical challenge, with re-operation rates reported up to 14% (3). …”
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Diagnosis and Treatment of Manifestations of Endothelial Dysfunction in ICU Patients with Severe Acute Pancreatitis by V. V. Kiselev, M. S. Zhigalova, S. S. Petrikov, E. V. Klychnikova, P. A. Yartsev

“…Traumatic tissue injury, followed by hypoperfusion, hemodilution, hypothermia, and acidosis cause acute post-traumatic coagulopathy. The inflammatory process activates the coagulation system, reduces the activity of natural anticoagulants and disrupts the functioning of the fibrinolytic system, thereby leading to thrombosis.   …”
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Biochemical and histological assessment of the hepatoprotective effects of Bryophyllum pinnatum leaf extract in Ketamine-induced liver toxicity in male Wistar rats by Precious Uahomo, Joshua Isirima

“…This study investigated the effects of B. pinnatum leaf extract on liver function biomarkers and histopathology in ketamine-induced hepatotoxicity in Wistar rats. …”
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Is Stretching exercises Superior to Steroids for Sustained Relief in Plantar Fasciitis? Evidence from a Prospective Study by Divya Nand Pandey, Harsh Pratap Singh, Chetan Singh, Shrikant Raj, Harshit Tripathi, Ayush Prakash

“…This study compares the short-term and long-term effectiveness of plantar fascia stretching exercises versus corticosteroid injections in improving pain and function. Materials and Methods: This prospective clinical trial included 100 patients randomly assigned to two treatment groups: One undergoing plantar fascia-specific stretching exercises with anti-inflammatory medications, contrast bath and shoe insole and the other receiving a single corticosteroid injection (Triamcinolone acetonide 1 mL i.e., 40 mg with 1 mL 2% lignocaine with 20 gauze needle) on medial to the heel pad on most tender point after local sensitivity followed by anti-inflammatory medications, contrast bath and shoe insole .Outcome measures included the Visual Analog Scale (VAS) and the foot and ankle ability measure (FAAM), recorded at baseline, and at 2, 6, 12, and 16 weeks post-treatment. …”
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