Further characterization and engineering of an 11-amino acid motif for enhancing recombinant soluble protein expression by Jiawu Bi, Elaine Tiong, Ying Sin Koo, Weibiao Zhou, Fong Tian Wong

“…Results A comprehensive analysis was performed to improve the characteristics of the 11-amino acid tag. …”
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Uji Kadar Albumin dan Pertumbuhan Ikan Gabus (Channa striata) dengan Kadar Protein Pakan Komersial yang Berbeda <Br><I>[Albumin Level Test and Snakehead Fish (Channa striata) Growt... by Moch. Amin Alamsjah, Galuh Ajeng Kusumaningrum, Endang Dwi Masithah

“…This fish as albumin source for hypoalbumin (lower albumin) patients and wound, both post operation wound and burn. Albumin have many sulfhydrile compound (SH) have a function as radikal bind. …”
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Development of a core outcome set for studies on prevention and management of pregnancy-associated venous thromboembolism (COSPVenTE): a study protocol by Rohan D’Souza, Alexandria King, Lizabeth Teshler, Nadine Shehata, Ann K Malinowski

“…A suggested solution is the development of a core outcome set (COS) that defines the minimum criteria for outcome reporting in clinical trials and prospective studies. COSs function to facilitate data harmonisation and increase homogeneity in outcome reporting while incorporating the voice of women in this population in the planning of research to inform their ongoing care.Methods and analysis The development of a COS for studies on pregnancy-associated VTE will comprise five steps. …”
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To Evaluate The Efficacy Of Intravenous Selenium Administration In Critically Ill Patients by Sudha puhal, Anju Ghai, Anju Rani, Rachana Verma, Sudhir Kumar Bisherwal

“…Clinical parameters including SOFA score, ICU and hospital stays, and duration of mechanical ventilation and biochemical parameters such as C-reactive protein (CRP), Interleukin-6 (IL 6), Se levels, and total leukocyte count (TLC) were assessed before Se administration and on the fifth day post-administration for analysis. Results: After administering Se injections, there was a significant increase in serum Se concentrations from 195.45±64.03 to 295.45±87.81 “p <0.001”. …”
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Polyamine-Mediated Growth Regulation in Microalgae: Integrating Redox Balance and Amino Acids Pathway into Metabolic Engineering by Leandro Luis Lavandosque, Flavia Vischi Winck

“…Polyamines (putrescine, spermidine, and spermine) biology in microalgae, particularly <i>Chlamydomonas reinhardtii</i>, is reviewed, exploring their critical function in modulating cell cycle progression, enzymatic activity, and stress responses through nucleic acid stabilization, protein synthesis regulation, and post-translational modifications. …”
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METTL3-YTHDF1 axis drives BCL-3 m6A methylation to promote the ferroptosis of brain microvascular endothelial cells during intracerebral hemorrhage by Hao Yin, Zhongying Ran, Tao Luo, Zexin Jin, Ying Tan, Jun Ma

“…Intracerebral hemorrhage (ICH) significantly impacts human health, with emerging evidence indicating that N6-methyladenosine (m6A) modifications serve a critical regulatory function in ischemic stroke. However, the underlying mechanisms remain largely unexplored. …”
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Dupilumab Efficacy in Patients with Type 2 Asthma with and without Elevated Blood Neutrophils by Eugene R. Bleecker, Reynold A. Panettieri, Njira L. Lugogo, Jonathan Corren, Nadia Daizadeh, Juby A. Jacob-Nara, Yamo Deniz, Paul J. Rowe, Angela Khodzhayev, Xavier Soler, Thomas J. Ferro, Christopher N. Hansen

“…In the phase 3 LIBERTY ASTHMA QUEST (NCT02414854), add-on dupilumab 200 and 300 mg every 2 weeks compared with matched placebo significantly reduced severe asthma exacerbations and improved forced expiratory volume in 1 s (FEV1) in patients with uncontrolled, moderate-to-severe asthma. This post hoc analysis explored the efficacy of dupilumab in patients with type 2 asthma enrolled in QUEST with or without elevated blood neutrophil counts. …”
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Physiological characteristics of reproductive-age patients with female sexual dysfunction and endometriosis (a comparison of clinical and laboratory parameters in different study g... by O. I. Kryzhanovska, L. M. Semeniuk

“…Post-hoc analysis (Mann–Whitney test) has shown that the mean scores for all categories of the Female Sexual Function Index (FSFI) questionnaire were statistically significantly higher in Group IA patients compared to those in Group II patients (p < 0.001). …”
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The Ellipsoid Zone Is a Structural Biomarker for Visual Outcomes in Diabetic Macular Edema and Macular Hole Management by Shivani Chaturvedi, Amisha Paul, Samya Singh, Levent Akduman, Sandeep Saxena

“…Measurements of EZ defects documented at the time of presentation and 12 weeks after intervention were analyzed using the caliper function of the machine. EZ restoration was graded, and a Pearson correlation analysis was performed. …”
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Resistance Training May Improve Rectus Femoris Muscle Parameters in Elderly Women by Zeinab Hooshmandi, Farhad Daryanoosh, Pegah Jahani

“…Introduction: One of the important issues in aging is sarcopenia characterized by muscle mass and function reduction. The present study investigated the effect of high intensity interval resistance training (HIIRT) on muscular parameters in sarcopenic elderly women. …”
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Comparison of clinical and economic outcomes between the direct anterior approach and the posterolateral approach for primary total hip arthroplasty by Paweł Skowronek, Michał Dębiński, Agnieszka Maksymiuk-Kłos, Andrzej Zalewski, Robert Jopowicz, Tomasz Sasinowski, Arkadiusz Madej

“…The aim of the study was to compare the two approaches DAA and PLA in terms of length of stay, economic outcomes, quality of life, hip joint function and hip joint awareness. Material and methods The study was performed as a retrospective analysis of 52 cementless total hip arthroplasty procedures performed by MIS DAA and 56 cementless THA performed by classic standard PLA. …”
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Re-evaluating the evidence of aflatoxin B1 intercalation into smectite interlayer: a review based on basal spacing data by Widyawanto Prastistho, Cintya Nurul Apsari, Niar Gusnaniar, Wawan Budianta, Michael Angelo B. Promentilla, Setyowati Triastuti Utami

“…Thus, further research of adsorption test to investigate the relationship between AfB1 uptake as a function of the hydration state on smectite minerals is strongly suggested.…”
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Institutional Media Freedom in the EU: Implications for Democratic Governance and Social Innovation

“…It highlights the role of free media in exposing corruption, educating citizens, and enabling accountability. The analysis points out that limitations on press freedom can function similarly to trade barriers by restricting access to credible information, thus affecting international trade flows. …”
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Efficacy of high-volume injections with and without corticosteroid compared with sham for Achilles tendinopathy: a protocol for a randomised controlled trial by Martin Underwood, Hylton B Menz, Dylan Morrissey, Anders Ploug Boesen, Shannon E Munteanu, Terry P Haines, David Connell, Rebecca S Kearney, Karin G Silbernagel

“…The primary outcome measure will be the Victorian Institute of Sport Assessment – Achilles (VISA-A) at 12 months post-randomisation, a validated, reliable and disease-specific measure of pain and function. …”
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Features of women’s reproductive dysfunctions associated with prolonged stressful situations by O. H. Horbatiuk, A. S. Shatkovska, A. P. Hryhorenko, O. V. Vaskiv, I. O. Bets, I. M. Kustovska, A. I. Petrash

“…The aim of the work was a comprehensive study of the hormonal function of pituitary gland, ovaries, thyroid gland and adrenal glands in women of reproductive age with various types of menstrual cycle disorders caused by a prolonged stressful situation. …”
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Trends in Clinico-radiological and Laboratory Characteristics of All-Cause Meningoencephalitis in Western Rajasthan by Ravi Krishna Kanth, Samhita Panda, Sarbesh Tiwari, Taruna Yadav, Gopal Krishana Bohra, Ravi Shekar Gadepalli

“…Fever, altered sensorium, speech disturbances, neck stiffness, albumin, total leukocyte count, erythrocyte sedimentation rate, C-reactive protein, kidney and liver function tests showed significant association with mortality. …”
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Strength characteristics in saturation process and rainfall-induced landslide failure mechanism of granite residual soil by Bing Lan, Bangzhong Jia, Yiying Wu, Yiying Wu, Xiaoyu Yi, Wenkai Feng, Yihe Li

“…Results reveal that shear strength declines nonlinearly with increasing moisture content and saturation duration: cohesion follows a quadratic function, while the internal friction angle adheres to a logarithmic relationship. …”
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Compositionally-driven surface nanostructuring on refractory compositionally complex alloys under low energy helium bombardment by Shane Evans, Justin Hamil, Matthew J. Baldwin, Daisuke Nishijima, Marlene I. Patino, Megan J. McCarthy, Andrew B. Kustas, Mary Alice Cusentino, Eric Lang

“…Molecular Dynamics simulations complement the experimental results, showing comparable helium bubble growth and migration as a function of compositional complexity. This work demonstrates the compositional dependence of surface nanostructure formation of compositionally complex alloys, important for future design of complex plasma facing materials in fusion reactors.…”
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Regulation of plant immunity through histone H3 β-hydroxybutyrylation-mediated transcriptional control by Qiutao Xu, Zhengting Chen, Rui Wang, Xuan Ma, Yuhang Duan, Du Hai, Jing Chen, Zhongyi Cheng, Lu Zheng, Junbin Huang, Jisen Zhang, Yu Zhao, Xiaoyang Chen

“…We demonstrated functional differences between H3K9bhb and the well-studied H3K9ac histone modification, particularly in regulating genes involved in the rice immune response. …”
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The “Great Meme War:” the Alt-Right and its Multifarious Enemies by Maxime Dafaure

“…This paper consequently leads to an analysis of real-life repercussions of such adversarial rhetoric, notably through examples of recent far-right domestic terrorism in the US, and to a reflection on their place in an age of post-truth, fake news, and alternative facts. …”
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