ER-PM membrane contact site regulation by yeast ORPs and membrane stress pathways. by Evan Quon, Aleksa Nenadic, Mohammad F Zaman, Jesper Johansen, Christopher T Beh

“…Yeast OSBP homologue (Osh) proteins are also implicated in membrane contact site (MCS) assembly, perhaps as subunits for multicomponent tethers, though their function at MCSs involves intermembrane lipid transfer. …”
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Automated Artery Detection and Stenosis Classification in CTA Using Deep Learning for Peripheral Arterial Disease by Ali M. O. A. Anwer, Hacer Karacan, Muhammed Rabee, Levent Enver, Gonca Cabuk

“…Experts manually annotated a subset of 13,439 slices for use in training and evaluating the model. Post-processed with HU-based vessel analysis and intersection-over-union (IoU) filtering, stenosis classification was more refined. …”
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The efficacy of controlled stepped intracranial decompression surgery in patients with craniocerebral injury by Xiaobin Huang, Cheng Yu, Xiaoyue Liao, Baizhuo Dong, Jun Zheng, Shanchi Zhang

“…Surgical parameters, treatment efficacy, complications, neurological function, and serum biomarkers (IL-6, CRP, NSE) were compared. …”
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Mixed Reality–Based Physical Therapy in Older Adults With Sarcopenia: Preliminary Randomized Controlled Trial by Yeongsang An, Seunghwa Min, Chanhee Park

“…Outcome measures included ultrasound imaging of quadricep muscle thickness, the Korean version of the Activities of Daily Living scale (Katz Index of Independence in Activities of Daily Living), the Activities-Specific Balance Confidence (ABC) scale, and the 12-Item Short-Form Health Survey. Statistical analysis was performed using repeated-measures ANOVA and Tukey post hoc tests. …”
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Application of intraoperative neurophysiological monitoring in unilateral biportal endoscopic lumbar spine surgery by Tian-Yu Bai, Hai Meng, Ji-Sheng Lin, Zi-Han Fan, Qi Fei

“…Methods A retrospective analysis was performed on 127 patients who underwent UBE lumbar spine surgery at Xicheng Branch of Beijing Friendship Hospital from January 2024 to September 2024. …”
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Ferroptosis and mitochondrial ROS are central to SARS-CoV-2-induced hepatocyte death by Cintia Cevallos, Patricio Jarmoluk, Franco Sviercz, Rosa Nicole Freiberger, Cynthia Alicia Marcela López, M. Victoria Delpino, Jorge Quarleri

“…Viral replication was quantified via RT-qPCR, nucleocapsid protein detection, and infectious particle titration. Mitochondrial function was assessed through mitochondrial membrane potential (ΔΨm), mROS production, and mitophagy analysis. …”
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Effect of probiotic-fermented milk containing Lactiplantibacillus pentoses strain HBUAS 53657 on serum glutathione peroxidase activity and pancreatic histopathology in hyperglycemi... by Rita Yaswir, Eti Yerizel, Netti Suharti, Cimi Ilmiawati

“… Background: Hyperglycemia is characterized by elevated blood glucose levels caused by impaired insulin production or function, leading to oxidative stress. Probiotic-fermented milk containing Lactiplantibacillus pentosus strain HBUAS 53657 (PFM) has antioxidant and antimicrobial properties that may reduce oxidative stress. …”
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Novel Heterozygous Sequence Variant in the HOXD13 Gene Underlie Non-syndromic Syndactyly by Safdar Abbas, Farooq Ahmad, Misbah Kanwal, Annum Sultan, Gulab Said, Muhammad Umair

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Effect of treatment modality on long-term outcomes in attention-deficit/hyperactivity disorder: a systematic review. by L Eugene Arnold, Paul Hodgkins, Hervé Caci, Jennifer Kahle, Susan Young

“…Studies with follow-up times <3 years reported benefit with treatment for 93% of outcomes, whereas those with follow-up times ≥3 years reported treatment benefit for 57% of outcomes. Post-hoc analysis indicated that this result was related to the measurement of outcomes at longer periods (3.2 versus 0.4 years) after treatment cessation in studies with longer total study length.…”
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Impact of Cochlear Trauma Degree and Localization on Intracochlear Electrocochleographic Recordings by David Bächinger, Merlin Schär, Ahmet Kunut, Rahel Bertschinger, Ivo Dobrev, Leanne Sijgers, Andreas H. Eckhard, Adrian Dalbert

“…Results: In case of grade 1 and 2 cochlear trauma, as determined by post-mortem histological analysis, we found that a reduction in intracochlear cochlear microphonic (CM) amplitude correlates more significantly with the location of the trauma than with its severity. …”
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The effect of kinesiophobia on gastrointestinal disorders in patients with lower extremity orthopedic surgery by Huseyin Gunes, Semra Bulbuloglu, Serdar Saritas, Ahmet Ozdemir

“…A personal information form, the Tampa Scale of Kinesiophobia (TSK), and the Gastrointestinal Symptom Rating Scale (GSRS) were used to collect data, and the obtained data were analyzed using descriptive statistics, one-way analysis of variance (ANOVA), paired-samples t-test, and post hoc tests when necessary.ResultsWhile 24.4% of the patients were aged 65–74 years, 51.5% were male. …”
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Effects of electroacupuncture on cognitive symptoms in major depressive disorder: a pilot study and randomized controlled trial [version 3; peer review: 1 approved, 2 approved with... by Chommakorn Thanetnit, Yindee Boontra, Muthita Phanasathit

“…Objectives To investigate the impact of electroacupuncture on cognitive function, quality of life (QoL), and depression severity in patients with major depressive disorder (MDD). …”
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Unraveling salivary microbiota diversity following kidney transplantation: insights from baseline peripheral blood lymphocyte subsets by Xuyu Xiang, Tianyin Wang, Peng Ding, Yi Zhu, Ke Cheng, Yingzi Ming

“…Our study provides novel insights into immune monitoring post-KT.…”
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The role of Tei index as an early predictor for evaluating experimental uremic cardiomyopathy model by Shi Cheng, Wei Lu, Jiarui Xu, Yong Yu, Yi Fang, Xiao Tan, Ruizhen Chen, Bo Shen, Xiaoqiang Ding, Yeqing Xie

“…Results The Tei index was significantly elevated in Nx mice despite preserved cardiac function and structural integrity at 8 weeks post-nephrectomy. …”
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The clinical application of mitoxantrone hydrochloride tracing in endoscopic radical resection of thyroid carcinoma by Xiaozhou Cheng, Lijun Chen, Honggang Zang, Yaping Li

“…Abstract To evaluate the effectiveness of tracer mitoxantrone hydrochloride injection (MHI) in mapping central lymph nodes and its role in preserving parathyroid function during endoscopic radical resection of thyroid carcinoma. …”
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Impact of Diagnosis of Urologic Cancer on Male Sexuality and Patients’ Perceptions of Health Professional's Approach by Rodrigo Barros, Angelo Maurílio Fosse Jr, Alex Schul, Gabriel Mangas, Caio Henrique da Silva Teixeira, Tiago Ninis, João Paulo Martins Carvalho, Luciano A. Favorito

“…Sexual activity was considered important by 90.5%, with 75.8% reporting decreased frequency post-diagnosis (99.5% were heterosexual and 72.5% were married). …”
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INFLUENCE OF MONETARY POLICY INSTRUMENTS AND INDICATORS ON DYNAMICS OF FINANCING INNOVATION: EMPIRICAL EVIDENCE by Anargul Belgibayeva, Anastasiia Samoilikova, Tetiana Vasylieva, Serhiy Lieonov

“…This one confirms that monetary instruments in Ukraine are not fully performing their regulatory function, in the context of stimulating innovation development. …”
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Positive Collaboration in Rehabilitation Nursing Enhances Fall Efficacy and Confidence in Elderly Patients with Cerebral Infarction by Luo F, Xu W, Xu Y, Lou L, Xu C

“…Patients were divided into a control group (n=53, receiving routine care) and an observation group (n=53, receiving positive collaboration rehabilitation nursing). Neurological function (NIHSS), negative emotions (SAS, SDS), fall efficacy (MFES), activities of daily living (ADL), quality of life (SS-QOL), rehabilitation confidence (CaSM), and nursing satisfaction (NSNS) were compared between the two groups.Results: The observation group showed significantly lower NIHSS scores at 2 weeks and 1 month post-intervention (P&lt; 0.05). …”
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Chemical constitutes and anti-hypertension potential of Gaocha (Acer ginnala Maxim) in spontaneously hypertensive rat by Wenzhao Wang, Jing Ma, Yafeng Ma, Yumeng Bao, Zijiang Long, Shengping Lei, Yan Xu, Qianying Dai, Liping Gao, Haiyan Wang

“…Gaocha is a kind of succedaneous tea beverage made by the tender shoots of Acer ginnala Maxim, widely distributed in China and Korea, which is used as a functional tea beverage with a long history dating back to 2000 BC. …”
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LncRNA NEAT1 participates in diminished ovarian reserve by affecting granulosa cell apoptosis and estradiol synthesis via the miR-204-5p/ESR1 axis by Li Dong, Haicui Wu, Fanghua Qi, Wen Chen, Yuan Xu, Min Li, Yuqi Wang, Rugen Yan, Pingping Cai

“…Abstract Long non-coding RNAs (lncRNAs) affect the biological functions of granulosa cells (GCs) through multiple mechanisms, including epigenetic regulation, transcriptional regulation, post-translational modification, and cell signaling. …”
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