A differentiated approach to the surgical treatment of intraarticular fracture of the proximal tibia by A.V. Kalashnikov, Y.M. Litun, Ye.E. Chip, A.M. Syvak

“…A comprehensive assessment of knee function was performed using the Knee Society Score. …”
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Effectiveness of a brain exercise program using game-based cognitive enhancement to reduce mild cognitive impairment among older adults in Pathum Thani Province, Thailand: a quasi-... by Panida Kunrit, Phannathat Tanthanapanyakorn, Nonlapan Khantikulanon, Sootthikarn Mungkhunthod, Chaninan Praserttai, Sasipa Rungrungrueang, Wanwisa Phonmamuang

“…Face-to-face interviews assessed outcomes at baseline, post-intervention, and 3-month follow-up. Data were analyzed using descriptive statistics and repeated-measures analysis of variance. …”
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The impact of preoperative anxiety and depression on the prognosis of patients with painful accessory navicular by Jia-chen Liang, Qiang Zan, Shi-Hang Cao, Xiao-cong Liu, Jing Huang, Yi Li, Jun-kui Xu

“…Furthermore, it investigated the differences between patients’ pre- and post-operatively, analyzing the impact on post-operative pain and functional recovery. …”
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Acute Aronia Juice Consumption Prior to Half-Marathon Races Affects Proteinuria-Induced Changes of Serum Protein Profiles by Marija Takić, Tamara Uzelac, Nevena Vidovic, Vuk Stevanovic, Ana Pantovic, Marija Glibetic, Vesna Jovanovic

“…Physical activity could lead to dehydration and post-exercise proteinuria. In several animal studies, it has been noticed that aronia juice consumption shows favorable effects on the kidney function. …”
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Potential therapeutic effects of IL28RA inhibition on acute myocardial infarction through phosphorylated JAK1/STAT1 signaling pathways by Ge Gong, Xiangxuan Chen, Xinghu Zhang, Jian Yin, Wenhui Wan

“…In a mouse model, cardiac function deteriorated and ventricular structural changes were observed 14 days post-myocardial infarction relative to controls. …”
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Changes in heart rate variability induced by E-sports activities by Ti Wu, Po-Yao Lee, Jie-An Tu, Hsin-Huan Wang, Hsin-Huan Wang, Hsueh-Chin Chao, Chia-Hsiang Chen, Jui-Hung Tu

“…Furthermore, pre-game HRV indices [e.g., Standard Deviation of NN intervals (SDNN), Root Mean Square of Successive Differences (RMSSD), Number of NN intervals differing by more than 50 ms (NN50), Percentage of NN50 (pNN50)] and high-frequency (HF) power and LF/HF Ratio were significantly higher than those recorded during and after gaming (p < 0.05).ConclusionE-sports gaming imposes stress and fatigue on HRV-related parameters, heightening sympathetic activity and suppressing parasympathetic function. Although certain indicators exhibited a trend toward recovery during the post-gaming rest period, complete recovery appears to require a longer duration. …”
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Mobilization with movement plus exercise versus exercise alone for patients with central sensitization associated with chronic subacromial pain syndrome: a sham-controlled randomiz... by Volkan Deniz, Bayram Kelle

“…The CSI was used to assess emotional and somatic symptoms associated with central sensitization; PPTs evaluated local and widespread pain hypersensitivity; and the Q-DASH assessed upper extremity physical function and symptoms. A two-factor repeated-measures analysis of variance (group × time) with Bonferroni post-hoc correction was performed to analyze the main outcome variables. …”
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Outcome of Transjugular Intrahepatic Portosystemic Shunt in Budd-Chiari Syndrome: Long-Term Outcomes of 118 Patients; A Single-center Experience by Mohamed Shaker, Mohammad Sakr, Hany Dabbous, Sara M. Abdelhakam, Ahmed Samir, Hend Ebada, Amir M. Farid, Mohamed El-Gharib, Ahmed Eldorry

“…Paired t-test was used to compare pre and post-TIPS MELD and Child-Pugh scores. Chi-square test and Kaplan–Meier survival curve were used to examine the association between short- and long-term occlusion, liver function and survival outcomes. …”
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Revealing the Immune Response of <i>Sitona callosus</i> Gyllenhal to Entomopathogenic Fungi <i>Beauveria bassiana</i> Infection Through Integrative Analyses of Transcriptomics and... by Nan Li, Xin Gu, Ming Xin, Xinpu Wang

“…Transcriptomic and metabolomic analyses were conducted to explore alterations in gene expression and metabolic processes in <i>S. callosus</i> at 48, 96, and 144 h post infection with <i>B. bassiana</i>. The transcriptomic analysis unveiled that <i>B. bassiana</i> infection boosted immune responses in tubercula, affecting carbohydrate metabolism, cytochrome P450 activity, lysosome function, apoptosis regulation, phagosome formation, glutathione metabolism, amino acid metabolism, and pathogen response pathways. …”
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Evidence from a mouse model that epithelial cell migration and mesenchymal-epithelial transition contribute to rapid restoration of uterine tissue integrity during menstruation. by Fiona L Cousins, Alison Murray, Arantza Esnal, Douglas A Gibson, Hilary O D Critchley, Philippa T K Saunders

“…Menses, characterised by the shedding of the upper functional layer of the endometrium, is the culmination of a cascade of irreversible changes in tissue function including stromal decidualisation, inflammation and production of degradative enzymes. …”
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Investigating Antecedents to Older Adults’ Uptake of Health Information Systems: A Quantitative Case Study of Electronic Personal Health Records by Reza Torkman, Amir Hossein Ghapanchi, Reza Ghanbarzadeh

“…Findings: the data analysis of the participants’ responses uncovered that seniors’ usage intention toward PHRs is a function of the PHR’s perceived usefulness (<i>p</i> < 0.01, OR = 2.5, 95% CI 1.5–4.1), perceived barriers (<i>p</i> < 0.05, OR = 1.3, 95% CI 0.8–2.1), perceived confidence (<i>p</i> < 0.05, OR = 1.6, 95% CI 1.0–2.5), and cues to action (<i>p</i> < 0.05, OR = 1.8, 95% CI 1.1–2.9). …”
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Void spot assay visualization optimization for use of Void Whizzard in rats (Rattus norvegicus) by Hannah Ruetten, Jadyn Bothe, Shannon Lankford, Gopal Badlani, James Koudy Williams

“…This study optimizes VSA by comparing post‐assay paper visualization techniques: bright field light (BF), ultraviolet light (UV), and ninhydrin spray (N). …”
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Several colors of scientific consulting: Ukrainian cases by Artem Artyukhov

“…Type of the article: Reflexive Preface The proliferation of unethical scientific consulting practices, particularly in post-Soviet contexts, poses significant threats to academic integrity by transforming legitimate knowledge transfer services into commercialized systems that fabricate academic outputs to meet formal performance metrics rather than supporting genuine research efforts. …”
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Effects of Eight Weeks of Endurance and Resistance Training on Serum Level of Apoptotic Indicators in Elderly Women by Parvin Mortezaei, Sajad Arshadi, Abdolali Banaeifar, Mojtaba Izadi

“…SPSS V.21, Shapiro-Wilk test, two-way mixed analysis of variance, and Bonferroni post hoc test were employed for statistical analysis (p<0.05). …”
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Safety, efficacy and health impact of electronic nicotine delivery systems (ENDS): an umbrella review protocol by Sonu Goel, Jagdish Kaur, Anil Chauhan, Arvind Vashishta Rinkoo, Muhammed Shabil

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An integrated population pharmacokinetic model of febuxostat in pediatric patients with hyperuricemia including gout and adult population of healthy subjects and patients with rena... by Ryutaro Iwama, Kimie Nishida, Daisuke Ishii, Takeshi Iijima

“…The range of steady‐state exposures (Cmax,ss and AUCτ,ss) for 5, 10, 20, and 30 mg of febuxostat in fed pediatric patients weighing 20 to 40 kg was within that for 10, 20, 40, and 60 mg of febuxostat in fed pediatric patients and adults weighing 40 to 120 kg. Post hoc estimates of CL/F, adjusted by body weight, differed little between pediatric patients and the adult population in the renal function categories of normal, mild dysfunction, and moderate dysfunction. …”
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Very Early Rehabilitation After Treatment with Intravenous Thrombolysis for Mild Acute Ischemic Stroke by Rahul R. Karamchandani, Liang Wang, Dale Strong, Alexis A. Mulvaney, Jonathan D. Clemente, Jeremy B. Rhoten

“…In the propensity score analysis of 73 matched pairs, EM was comparable to usual care with respect to 90-day functional outcome (OR for higher mRS 0.891, <i>p</i> = 0.7). …”
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Co-Benefits of Largescale Organic farming On huMan health (BLOOM): Protocol for a cluster-randomised controlled evaluation of the Andhra Pradesh Community-managed Natural Farming p... by Lindsay M Jaacks, Lilia Bliznashka, Peter Craig, Michael Eddleston, Alfred Gathorne-Hardy, Ranjit Kumar, Sailesh Mohan, John Norrie, Sheril Rajan, Aditi Roy, Bharath Yandrapu, Nikhil Srinivasapura Venkateshmurthy, Poornima Prabhakaran

“…Analysis will be on an intention-to-treat basis with an a priori secondary analysis to estimate the per-protocol effect of APCNF on the outcomes. …”
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Gut Microbiota Alteration in Healthy Preterm Infants: An Observational Study from Tertiary Care Center in India by Prabavathi Devarajalu, Jogender Kumar, Sourabh Dutta, Savita Verma Attri, Jayakanthan Kabeerdoss

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Unveiling the Mechanisms of a Remission in Major Depressive Disorder (MDD)-like Syndrome: The Role of Hippocampal Palmitoyltransferase Expression and Stress Susceptibility by Careen A. Schroeter, Anna Gorlova, Michael Sicker, Aleksei Umriukhin, Alisa Burova, Boris Shulgin, Sergey Morozov, Joao P. Costa-Nunes, Tatyana Strekalova

“…Post-translational modifications of proteins via palmitoylation, a thioester linkage of a 16-carbon fatty acid to a cysteine residue, reversibly increases their affinity for cholesterol-rich lipid rafts in membranes, changing their function. …”
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