Spider Cage Therapy's Impact on GMFM-88 in Iraqi Infants with Cerebral Palsy in Two Rehabilitation Centers by Nizar Jassim, Amenah Mohammed, Hayder Abbood, Naeem Almashhadani

“…The intervention consisted of structured sessions within the spider cage aimed at improving motor function. Data analysis was conducted using SPSS (Version 26.0). …”
Get full text

Belatacept-based immunosuppression in heart transplant recipients: A single center experience by Wairimu Magua, PhD, MS, Maggie Wang, MD, MSc, Darlington Pobee, MD, Anna Morris, PhD, Alexis K. Okoh, MD, Emily M. Eichenberger, MD, MHS, Geeta M. Karadkhele, MS, Divya Gupta, MD, J. David Vega, MD, Christian P. Larsen, MD, PhD, Anne Van Beuningen, MD, Alanna A. Morris, MD MSc

“…Renal function and cytomegalovirus viremia were examined as secondary outcomes. …”
Get full text

Determinants of carotid intima-media thickness in patients with asymptomatic unstable plaques: a population-based cross-sectional study in rural China by Ping Tang, Yuting Lu, Huihui Xue, Juan Hao, Haotian Wen, Jun Tu, Jun Tu, Jun Tu, Jun Tu, Ran Chen, Juan Li, Jinghua Wang, Jinghua Wang, Jinghua Wang, Jinghua Wang, Xianjia Ning, Xianjia Ning, Xianjia Ning, Xianjia Ning, Chunsheng Yang, Yan Li, Lifeng Wang

Get full text

Mental well‐being in prostate cancer: A multi‐institutional prospective cohort study by Oliver Brunckhorst, Jaroslaw Liszka, Callum James, Jack B. Fanshawe, Mohamed Hammadeh, Robert Thomas, Shahid Khan, Matin Sheriff, Gordon Muir, Hashim U. Ahmed, Mieke Van Hemelrijck, Robert Stewart, Prokar Dasgupta, Kamran Ahmed

“…Patient factors for poorer mental well‐being included younger age, a previous psychiatric history, social deprivation, poorer baseline mental health symptoms and poorer baseline sexual and urinary function. Symptom trajectory analysis demonstrated the increasing symptom load in body image and masculine self‐esteem experienced post any active treatment modality, with more stable scores for other mental well‐being measures. …”
Get full text

Identification of potential pathogenic genes associated with the comorbidity of rheumatoid arthritis and renal fibrosis using bioinformatics and machine learning by Jiao Qiu, Yalin Xu, Luyuan Tong, Xingchun Yang, Xiao Wu

“…Subsequently, functional enrichment analysis was performed to clarify the biological functions of these genes. …”
Get full text

Peak Tricuspid Regurgitation Jet Velocity and Kidney Outcomes in Patients With Heart Failure With Preserved Ejection Fraction by Tatsufumi Oka, Hocine Tighiouart, Wendy McCallum, Marcelle Tuttle, Jeffrey M. Testani, Mark J. Sarnak

“…Methods: This post hoc analysis of the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) trial analyzed participants with a left ventricular ejection fraction (LVEF) of ≥45% who had pTRV measured by echocardiography at baseline. …”
Get full text

Advanced 4-chamber echocardiography techniques enable clinically matched precise characterization of heart disease progression in mice by Ege Kacira, Mariam F. Oueis, Nawal H. Tamimi, Sarah L. Sturgill, Xianyao Xu, Thomas J. Hund, Mark T. Ziolo, Yuchi Han, Isabelle Deschênes, Ji-dong Fu

“…Methods: To overcome this limitation, we developed an A4CLAX imaging approach for mice and performed a comparative analysis with established echocardiographic methods to assess cardiac function in healthy mouse hearts. …”
Get full text

Association of Comprehensive Geriatric Assessment’s Component and Sarcopenia in Elderly by Diar Meitha Wardhana, Novira Widajanti, Jusri Ichwani

“…Variables included in multivariate analysis were age, sex, nutritional status, comorbidities, cognitive status, and functional status. …”
Get full text

Cerebellar Information Processing in Relapsing-Remitting Multiple Sclerosis (RRMS) by E. Lesage, M. A. J. Apps, A. L. Hayter, C. F. Beckmann, D. Barnes, D. W. Langdon, N. Ramnani

“…Hemodynamic activity in some patient populations with CNS pathology are not well understood and may be atypical, so we avoided analysis strategies that rely exclusively on models of hemodynamic activity derived from the healthy brain, using instead an approach that combined a ‘model-free’ analysis technique (Tensor Independent Component Analysis, TICA) that was relatively free of such assumptions, with a post-hoc ‘model-based’ approach (General Linear Model, GLM). …”
Get full text

Exosomal circ_0093708 as a potential ferroptosis biomarker in cerebral ischemia–reperfusion injury by Shuyin Ma, Xiaodong Zhang, Jiaxin Fan, Mengying Chen, Qingling Yao, Nan Zhang, Kaili Shi, Shuang Du, Yuxuan Cheng, Huiyang Qu, Minyu Duan, Han Yang, Tiantian Gao, Shuqin Zhan

“…By further establishing a ferroptosis model and inhibiting DUSP1 with drugs, we further explored the potential function of DUSP1 in ferroptosis. The role of miR-101-3p was assessed in CI/RI models, while the diagnostic value of exosomal circular RNA was evaluated using receiver operating characteristic curve analysis.ResultsCombined differential analysis revealed PTGS2 and DUSP1 as ferroptosis-associated genes potentially regulated by exosomal circRNAs. …”
Get full text

Restriction of work in retail on weekends and holidays (Polish experience) by Jakub Stelina

“…After transition period a total ban on working on Sundays and holidays in shops and other retail (except some special sales places, such as post offices, ticket offices etc.) will be established. …”
Get full text

Peripheral blood transcriptomic differences predict depression status in individuals undergoing bariatric surgery by Rebecca Milton, Anna P. McLaughlin, Nicole Mariani, Melisa Kose, Zuzanna Zajkowska, Giulia Lombardo, Naghmeh Nikkheslat, Esperanza Perucha, Valeria Mondelli

“…Data were analysed for differential expression and gene set enrichment across the 3 groups of interest. Analysis of the differential gene expression showed seven genes differentially expressed across the three groups, with genes mainly involved in immune activation or synaptic function. …”
Get full text

Observation on the efficacy of TPO receptor agonists and platelet transfusion in chemotherapy-induced thrombocytopenia in malignant tumors by Huan Hu, Dongmei Lei, Yan Liang

“…Regarding coagulation indices, post-treatment levels of APTT and PT decreased, while FIB levels increased in all three groups (P < 0.05). …”
Get full text

Comparison of liver injury and inflammatory response following conventional and drug-eluting bead transcatheter chemoembolization in hepatocellular carcinoma by Ran You, Bin Leng, Chendong Wang, Zeyu Yu, Lingfeng Diao, Ya Lu, Qingyu Xu, Guowen Yin

“…Serum levels of hepatic function indicators and inflammatory cytokines were evaluated before treatment and five days post-treatment. …”
Get full text

Practical Anemia Bundle for Sustained Blood Recovery (PABST-BR) in critical illness: a protocol for a randomised controlled trial by Laurie Meade, Andrea Cheville, Matthew A Warner, Phillip J Schulte, Daryl J Kor, Ognjen Gajic, Ronald S Go, William B Beam, Jonathan E Charnin, Kim A Droege, Brenda K Anderson, Matthew L Johnson, Brad Karon

“…However, the impact of interventions designed to attenuate or treat anaemia during critical illness on post-hospitalisation haemoglobin recovery and functional outcomes is unclear.Methods and analysis The Practical Anemia Bundle for Sustained Blood Recovery (PABST-BR) clinical trial is a pragmatic, open-label, parallel group, single-centre, randomised clinical trial assessing the impact of a multifaceted anaemia prevention and treatment strategy versus standard care for improvement of haemoglobin concentrations and functional outcomes after critical illness. …”
Get full text

Comprehensive biomarker assessment for predicting severe acute kidney injury and need of kidney replacement therapy in liver transplantation patients by Camila Lima, Gillene Santos Ferreira, Maria de Fátima Fernandes Vattimo, Luciana Bertocco de Paiva Haddad, Luiz Marcelo Malbouisson, Luiz Augusto Carneiro D’Albuquerque, Alexandre Toledo Maciel, Etienne Macedo

“…This study aimed to determine whether a comprehensive assessment of kidney function using nineteen serum and urinary biomarkers (BMs) within the first 48 h post-LT could enhance the prediction of severe acute kidney injury (AKI) and the need of kidney replacement therapy (KRT) during the first postoperative week.Methods Blood and urine (U) samples were collected during the pre- and postoperative periods. …”
Get full text

Plasma proteomics in children with new-onset type 1 diabetes identifies new potential biomarkers of partial remission by Olivier G. Pollé, Sébastien Pyr dit Ruys, Julie Lemmer, Camille Hubinon, Manon Martin, Gaetan Herinckx, Laurent Gatto, Didier Vertommen, Philippe A. Lysy

“…We analyzed the plasma of children with new-onset T1D to identify biomarkers present at diagnosis that predicted PR at 3 months post-diagnosis. We first performed an extensive shotgun proteomic analysis using Liquid Chromatography-Tandem-Mass-Spectrometry (LCMS/MS) on the plasma of 16 children with new-onset T1D and quantified 98 proteins significantly correlating with Insulin-Dose Adjusted glycated hemoglobin A1c score (IDAA1C). …”
Get full text

Reconstruction options in pediatric population with hemi or total mandibulectomy defects: A systematic review by Adity Bansal, Shakil Ahmed Nagori, Ashi Chug, Ashutosh Dixit, Rebecca Chowdhry, Srinivas Gosla Reddy

“…Though minor complications were observed, success was observed in all cases post reconstruction with either fibula or CCG graft, defined either by function, or growth. …”
Get full text

An intact S-layer is advantageous to Clostridioides difficile within the host. by Michael J Ormsby, Filipa Vaz, Joseph A Kirk, Anna Barwinska-Sendra, Jennifer C Hallam, Paola Lanzoni-Mangutchi, John Cole, Roy R Chaudhuri, Paula S Salgado, Robert P Fagan, Gillian R Douce

“…Comparative RNA sequencing (RNA-Seq) analysis of in vitro grown isolates revealed large changes in gene expression between R20291 and FM2.5. …”
Get full text

Study of the Repair Action and Mechanisms of a Moisturizing Cream on an SLS-Damaged Skin Model Using Two-Photon Microscopy by Yixin Shen, Ying Ye, Lina Wang, Huiping Hu, Caixia Wang, Yuxuan Wu, Dingqiao Lin, Jiaqi Shen, Hong Zhang, Yanan Li, Peiwen Sun

“…This study highlights the utility of TPM as a groundbreaking tool in cosmetic dermatology, offering real-time analysis of the effects of skincare products on skin structure and function.…”
Get full text