Polygenic risk score for acute rejection based on donor-recipient non-HLA genotype mismatch. by Rui Cao, David P Schladt, Casey Dorr, Arthur J Matas, William S Oetting, Pamala A Jacobson, Ajay Israni, Jinbo Chen, Weihua Guan

“…To reduce the risk of post-transplant AR, determination of kidney transplant donor-recipient mismatching focuses on blood type and human leukocyte antigens (HLA), while it remains unclear whether non-HLA genetic mismatching is related to post-transplant complications.…”
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Effect of hyperbaric oxygen therapy on ataxia: A case report by Vicktoria Elkarif, Amir Hadanny, Ruth Tuck Harpaz, Efrat Sasson, Shai Efrati

“…Two patients, aged 73 and 57, were presented with ataxia characterized by impaired static and dynamic balance, uncoordinated gait, and reliance on walking aids following stroke and brain injury, respectively. Pre and post-treatment evaluation included neuroimaging, gait analysis, and physical/functional assessment. …”
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Acute changes in left ventricle end-diastolic pressure in patients undergoing nonprimary percutaneous coronary intervention by Arjun Tandon, Salini Mukhopadhyay, Soumik Ghosh, A. Lavakumar, Kumar Amit, Vikas Agrawal

“…Statistical analysis included Mann–Whitney and Kruskal–Wallis tests, with P < 0.05 considered statistically significant. …”
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Risk assessment of heavy metal toxicity induced by platinum accumulation in tumor patients by Yuling Zhang, Pi Guo, Xiaoting Huang, Yi-Wei Xu, Zhiwei Zheng, Ling Fang

“…Discussion and Conclusions Platinum accumulation, by disrupting the red blood cell system and liver and kidney function, influences fatigue severity and common adverse reactions in patients during the post-chemotherapy recovery period.…”
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The influence of identity-oriented psychotrauma therapy on Hashimoto disease activity: a randomised controlled trial by Maria-Magdalena Macarenco, Cristian Opariuc-Dan, Teodora Georgescu

“…Outcomes included thyroid peroxidase (TPO-ab) and thyroglobulin (TG-ab) antibodies, along with depression, anxiety, stress, dissociation, alexithymia, and anger, assessed at baseline, post-treatment, and 3-month follow-up. A series of 2-way mixed-model ANOVAs and Bonferroni-corrected post-hoc tests were used. …”
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Conical Chitosan Conduits Combined With Methylcobalamin for Sciatic Nerve Transposition Repair by Qicheng Li, Fengshi Zhang, Shiyan Liu, Yusong Yuan, Yuhui Kou

“…Additionally, we administered MeCbl at various concentrations to evaluate post-surgical adjuvant treatment effect. At 16 weeks post-surgery, gait analysis, electrophysiology testing, transmission electron microscopy (TEM) observation, toluidine blue staining, immunofluorescence staining, muscle wet weight determination and Masson’s trichrome staining were performed to assess nerve regeneration and reinnervation of gastrocnemius. …”
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Importance of benzoyltransferase GcnE and lysine benzoylation of alcohol dehydrogenase AdhB in pathogenesis and aflatoxin production in Aspergillus flavus by Xuan Chen, Lihan Wu, Yuqi Zhang, Sen Wang, Shihua Wang

“…However, whether Kbz exists in pathogenic fungi and its function remains unknown. Here, we demonstrated for the first time that Kbz is present in Aspergillus flavus and identified 60 benzoylated sites on 46 benzoylated proteins by global benzoylome analysis. …”
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Comparison of continuous Serratus Anterior Plane Block (cSAPB) with bupivacaine versus single liposomal bupivacaine block in postoperative analgesia after Video-Assisted Thoracosco... by Mingyue Zhang, Zhuo Zheng, Xianfeng Xie, Yuee Dai, Maosen Zhao, Ke Gao, Shaoxing Liu

“…The primary outcome measure was the Quality of Recovery (QoR-15) scores at 24 and 48 h post-surgery. Secondary outcomes included: pain intensity assessed using the Visual Analog Scale (VAS) pain scale at rest and during deep breathing at 24 and 48 h postoperatively, postoperative pulmonary function, total opioid consumption during and after surgery, and adverse events. …”
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An Epigenetic Locus Associated with Loss of Smell in COVID-19 by Elif Sibel Aslan, Kenneth White, Gulsen Meral, Zeyneb Nur Akcay, Aytug Altundag, Savas Gur, Mehmet Dokur, Mehmet Akif Baktir, Lutfiye Karcioglu Batur

“…While many patients regain olfactory function within weeks, a significant portion experience persistent anosmia lasting over a year post-infection. …”
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Effect of Sensory Integration Therapy on Attention Span and Gross Motor Skills in Children with Down Syndrome: A Quasi-experimental Study by Manshi Baberwal, Dimple Choudhry, Anjali, Anshu Kumari, Mallika Jhandai, Pankaj Bhardwaj, Ekta

“…Attention span was measured using Stroop colour and Word Test and gross motor skills were measures with the help of {Gross Motor Function Measure 88 (GMFM-88)}. The data was analysed with the help of independent t-test (for between-group analysis) and repeated measures Analysis of Variance (ANOVA) (for within-group analysis). …”
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Protocol for a Field Trial of a Hearing and Vision Support Intervention for People Living in Long‐Term Care in Australia by Carly Meyer, Najwan El‐Saifi, Naomi Rose, Kasia Bail, Colette Browning, Dayna Cenin, Antonio Ahumada‐Canale, Megan Campbell, Tim England, Melanie Ferguson, Yuanyuan Gu, Reema Harrison, Chyrisse Heine, Lisa Keay, Sheela Kumaran, Iracema Leroi, Gerald Liew, Angelita Martini, Ralph Martins, John Newall, Smriti Raichand, Emma Scanlan, Hamid R. Sohrabi, Melinda Toomey, Johanna Westbrook, Piers Dawes

“…Methods and Analysis A prospective pre−post‐intervention trial within long‐term care will be conducted, including three groups: residents (n = 87), informal caregivers (n = 87) and long‐term care workers (n = 40). …”
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Evaluation of transcriptomic changes after photobiomodulation in spinal cord injury by Andrew R. Stevens, Mohammed Hadis, Hannah Alldrit, Michael R. Milward, Valentina Di Pietro, Deena M. A. Gendoo, Antonio Belli, William Palin, David J. Davies, Zubair Ahmed

“…Further findings from pathway analysis suggest that downregulation of metabolism-associated pathways is a mechanism by which acute post-injury mitochondrial dysfunction may be averted by PBM therapy.…”
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Therapeutic doses of efzofitimod demonstrate efficacy in pulmonary sarcoidosis by Ogugua Ndili Obi, Robert P. Baughman, Elliott D. Crouser, Mark W. Julian, Landon W. Locke, Abhijeeth Chandrasekaran, Pavithra Ramesh, Nelson Kinnersley, Vis Niranjan, Daniel A. Culver, Peter H.S. Sporn

“…Methods Peripheral blood mononuclear cells incubated with tuberculin-coated beads were exposed to varying concentrations of efzofitimod in an in vitro assay to determine concentrations that inhibited granuloma formation. In the post hoc analysis, we compared time-to-first-relapse and changes in pulmonary function after a protocolised corticosteroid taper in the Therapeutic and Subtherapeutic groups. …”
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Classification of left and right-hand motor imagery in acute stroke patients using EEG microstate by Shiyang Lv, Xiangying Ran, Mengsheng Xia, Yehong Zhang, Ting Pang, Xuezhi Zhou, Zongya Zhao, Yi Yu, Zhixian Gao

“…Microstate features hold significant potential for both post-stroke brain function assessment and the optimization of BCI systems. …”
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β2 integrin regulates neutrophil trans endothelial migration following traumatic brain injury by Lei Li, Ruilong Peng, Cong Wang, Xin Chen, Dilmurat Gheyret, Siyu Guan, Bo Chen, Yafan Liu, Xilei Liu, Yiyao Cao, Cha Han, Jianhua Xiong, Fanjian Li, Taoyuan Lu, Haoran Jia, Kaiji Li, Jinchao Wang, Xu Zhang, Jianye Xu, Yajuan Wang, Xin Xu, Tuo Li, Jianning Zhang, Shu Zhang

“…The precise molecular controls that dictate the inflammatory behavior of neutrophils post-TBI, however, remain largely elusive. Our comprehensive analysis of the molecular landscape surrounding the trauma in TBI mice has revealed a significant alteration in the abundance of β2 integrin (ITGB2), predominantly expressed by neutrophils and closely associated with immune responses. …”
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Efficacy of Nirmatrelvir tablet/Ritonavir tablet in patients infected with COVID-19 aged 90 years and older by WEI Xueman, ZHANG Jingxiang, LIU Tan

“…A retrospective research method was employed to gather and compare patitents’ clinical laboratory data before and after antiviral treatment, such as blood routine tests, inflammatory markers, coagulation function tests, liver and renal function tests, electrolyte levels, and blood gas analysis, between the drug group and the control group. …”
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Microcirculatory dysfunction in patients with acute anterior myocardial infarction combined with new complete right bundle branch block by Hong Liu, Yu Yuan, Yu Dong, Ying Yang, Xitong Yang, Biao Sun, Lilan Ma, Tao Li, Xin-Hua Wu

“…Data on demographics and hospitalization were collected, and clinical features and prognoses were compared. Post-PCI microcirculatory function was further characterized using coronary angiography-derived index of microcirculatory resistance (caIMR), thrombolysis in myocardial infarction (TIMI) grade flow, corrected TIMI flow frame count (CTFC) of the infarct-related artery, and ST segment regression in electrocardiograph (STR). …”
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The Modified Canine Groove Model of Osteoarthritis by Goran S. van der Weiden, Björn P. Meij, Amy van de Belt, Roel J. H. Custers, Sanne K. Both, Marcel Karperien, Simon C. Mastbergen

“…Both groups were monitored up to 45 weeks post-surgery. Pain/function was assessed by force plate analysis, and cartilage integrity, chondrocyte activity, and synovial inflammation were evaluated on the surgically untouched tibial plateaus by macroscopic, histologic, and biochemical analyses. …”
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Efficacy of tezepelumab in patients with severe asthma and persistent airflow obstruction by Elliot Israel, Mario Castro, Christopher S. Ambrose, Jean-Pierre Llanos, Nestor A. Molfino, Nicole L. Martin, Sandhia S. Ponnarambil, Neil Martin

“…Methods PATHWAY (phase 2b) and NAVIGATOR (phase 3) were multicentre, randomised, double-blind, placebo-controlled studies. This post hoc analysis included PATHWAY and NAVIGATOR patients who received tezepelumab 210 mg or placebo every 4 weeks for 52 weeks. …”
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Electrophysiological Evidence on Mirror Therapy for Promoting Perceptuo-Motor Processes in Stroke Patients by Li Ding, Dan Wang, Chengcheng Wu, Xu Wang, Jinyang Zhuang, Xiaoli Guo, Jie Jia

“…Before and after 4-week intervention, the HMR task was performed, and its behavioral performance and EEG characteristics were measured and correlated with clinical outcomes. Behavioral analysis showed that enhanced accuracy of the HMR task, correlating with greater improvement in upper extremity motor function, was only observed in the MG. …”
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