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  1. 2361

    The potential biomarker value of soluble CD36 in the treatment of diabetic kidney disease: evidence from GLP-1 and insulin interventions by Wenxuan Li, Yangang Wang

    Published 2025-05-01
    “…Clinical parameters including sCD36, urinary albumin-to-creatinine ratio (UACR), lipid profile, glycemic markers, and islet function indices were assessed at baseline and post-treatment. …”
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  2. 2362

    Significance of additional pulmonary blood flow between second and third stage in Fontan pathway by Katarzyna Januszewska, Pawel Nawrocki, Andreas Bruenen, Alexander Schnabel, Edward Malec

    Published 2024-11-01
    “…Results Preoperative echocardiography showed no differences in ventricular function (good – 105[95%] vs. 65[98.5%]; reduced – 9[5%] vs 1[1.5%]; p = 0.07) or AV valve function (p = 0.78). …”
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  3. 2363

    Research and application of image recognition-based identification for flesh browning of loquat fruits by CHEN Yujia, DENG Chaojun, ZHANG Tingting, WANG Xiuping, CHEN Xiuping, ZHAO Jianing, MA Cuilan, JIANG Jimou

    Published 2025-02-01
    “…According to the membership function ranking by principal component analysis, the browning resistance of the 10 loquat resources from strong to weak was: Yanhong, Ruisui, Huangjinkuai, Zhongshudaxiang, Muluo Loquat, Zhongbai, Guifei, Sanyuebai, Baixuezao, Guofenben. …”
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  4. 2364
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  6. 2366

    Effective implementation of ESG principles under technological sovereignty by Dovbiy Irina, Egorova Alexandra, Danilov Ilia

    Published 2024-01-01
    “…In the meantime, the sanctions pressure which began in 2014, compounded by pandemic restrictions and post-pandemic exacerbation, brought about a new way of revitalization for the development of the principles of “Environment”, “Society”, “Governance” - different from the previously accepted one in the global economy. …”
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  7. 2367

    Low-complexity signal detection algorithm for the power splitting receiver scheme by WANG Yanyan, LI Qidi, TANG Xiaohu

    Published 2024-04-01
    “…Firstly, considering the influence of antenna noise, post-processing noises, and power splitting factor, a splitting receiver architecture was designed, and a simplified two-dimensional received signal model was further established. …”
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  8. 2368

    Image-Building of Chinese Motorcycle Enthusiasts on Chinese Social Media Douyin by Zhang Ziliang

    Published 2024-01-01
    “…In the post-COVID era, the rise of domestic motorcycle culture and platforms like Douyin have given motorcycles stronger social communication attributes, reducing their function as mere tools. …”
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  9. 2369
  10. 2370

    Urinary disorders in patients diagnosed with organic brain pathology by P. P. Palatkin, N. G. Konovalova, O. V. Zhatko

    Published 2024-09-01
    “…To analyse the impaired function of lower urinary tracts in patients with organic brain pathology.Materials & methods. …”
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  11. 2371

    Examining the Intersection of Educational Administration, Power, and Religion in Iran's Historical Social Context: A Bourdieusian Perspective by Mohammad Akhondi, Rezvan Hosseingholizadeh, Mohsen Noghani Dokht Bahmani, Shahram Yousefifar

    Published 2024-03-01
    “…Therefore, utilizing the method of document research and employing the thematic analysis technique aligned with the Bourne and Clark approach, as well as the Atrayd Sterling model, the social history of Iran was studied in two periods: pre-Islamic (Ancient Iran) and post-Islamic (up to the mid-Qajar period and modern educational developments). …”
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  12. 2372

    Mathematical model for prediction of Tuberculosis in Nigeria using hybrid fractional differential equations and artificial neural network methods by Samson Linus Manu, Shikaa Samuel, Taparki Richard, Eshi Priebe Dovi

    Published 2025-06-01
    “…The data used for the analysis were obtained from the TB report by the World Health Organisation (WHO) TB Data Base, Nigeria Dash Board, from the years 2010–-2020. …”
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  13. 2373
  14. 2374

    Integrated omics revealed the altered colonic microenvironment after inhibition of peripheral serotonin synthesis by LP533401 by Yidan Ling, Ziyu Liu, Shuibing Han, Haiqin Wu, Chunlong Mu, Weiyun Zhu

    Published 2024-12-01
    “…Abstract Gut‐derived 5‐hydroxytryptamine (5‐HT), known as serotonin, plays a crucial role in regulating gastrointestinal functions. However, the impact of disruptions in gut‐derived 5‐HT synthesis on the early gut microbiome and intestinal microenvironment remains unclear. …”
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  15. 2375

    LncRNA XIST promoted the stability of TLR9 mRNA in a FUS-dependent manner to facilitate aerobic glycolysis and proliferation in Th17/CD4+T cells by Wu Yan-ping, Ma Xiao, Han Si-ping, Wang Xiao-qin

    Published 2022-05-01
    “…ObjectiveTo explore the expression and function of lncRNA XIST in Th17 cells in IgA nephropathy (IgAN) and examine the regulation of lncRNA XIST on TLR9 mRNA expression.MethodsCD4+T cells were isolated from peripheral blood mononuclear cells (PBMCs) and induced to differentiate into Th17 cells.XIST was over-expressed and silenced by plasmid transfection.Proliferation and apoptosis of Th17 cells with different levels of XIST expression were detected by flow cytometry and CCK-8 assay.Levels of XIST,TLR9 mRNA and protein were detected by quantitative reverse transcription-polymerase chain reaction (qRT-PCR) and Western blot.The effect of XIST on TLR9 expression was predicted by luciferase report analysis and TLR9 mRNA half-life detection.Potential RNA-binding proteins interacting with XIST were searched through Starbase database and detected by RNA immunoprecipitation and Western blot.GraphPad8.0 was utilized for statistical analysis and variables were expressed as average±SD.Student T test or one-way ANOVA was employed.ResultsXIST was distributed predominantly in cytoplasm.It hinted that XIST might be involved in post-transcriptional regulation.A down-regulation of lncRNA XIST expression promoted apoptosis and DNA damage and arrested cell proliferation by regulating TLR9.With an over-expression of lncRNA XIST,TLR9 expression spiked and XIST up-regulated the expression of TLR9 by promoting the stability of TLR9 mRNA.As an RNA-binding protein (RBP),FUS interacted with XIST and FUS antibodies could significantly enrich XIST transcripts.A down-regulation of lncRNA XIST expression had no effect on FUS protein expression.It suggested that XIST might affect FUS function rather than expression.It was further confirmed that a down-regulation of XIST significantly reduced FUS-TLR9 mRNA binding and FUS over-expression rescued a down-regulation and degradation of TLR9 mediated by si-XIST.ConclusionlncRNA XIST and TLR9 play a critical role in Th17 cell proliferation in IgAN through a FUS-mediated signaling pathway.This finding provides new therapeutic ideas for IgAN..…”
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  16. 2376
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    The advantages of artificial intelligence-assisted total hip arthroplasty: A randomized controlled trial followed by 12 months by Gang Zhang, Zixuan Liu, Diaodiao Wang, Zhuang Tian, Qi Yao

    Published 2024-11-01
    “…The operation time for AI-assisted total hip arthroplasty was 104.32 ± 18.10 min, which was shorter than that of the traditional two-dimensional X-ray planning group (P < 0.05). At 3 months post-operation, the grade of Harris score for hip function in the AI planning group was significantly better than that in the traditional two-dimensional X-ray planning group (P < 0.05). …”
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  18. 2378

    Exploration of phosphoproteomic association during epimorphic regeneration by Sarena Banu, P V Anusha, Komal Mandal, Mohammed M Idris

    Published 2025-02-01
    “…Understanding these precise modifications and their impact on protein function could shed light on the remarkable regenerative capacity of tissues, with potential implications for therapeutic interventions. …”
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  19. 2379

    Influences of social support following hip-fracture surgery for older adults with cognitive impairment and their family caregivers by Ming-Yueh Tseng, Jersey Liang, Ying-Jen Chen, Chi-Chuan Wu, Yea-Ing L. Shyu

    Published 2025-07-01
    “…Perceived social support was assessed one month post-discharge using the Medical Outcomes Study Social Support Survey (MOS-SSS) and categorized as good (score = 95) or poor (< 95). …”
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  20. 2380

    Brain stimulation enhances dispositional mindfulness in PTSD: an exploratory sham-controlled rTMS trial by Kaveh Rayani, Andrea Grabovac, Peter Chan, Peter Chan, Stefanie Montgomery, Mohammad-Reza Ghovanloo, Matthew D. Sacchet

    Published 2025-04-01
    “…Non-invasive repeated transcranial magnetic stimulation (rTMS) of the dorsolateral prefrontal cortex (DLPFC) has been shown to regulate mood and improve PTSD symptoms.MethodsThis is a retrospective chart analysis of data collected pre-treatment, post-treatment, and at three-month follow-up in a single-site, double-blind, sham-controlled trial of right DLPFC rTMS. 31 participants diagnosed with PTSD were recruited for this pilot study. …”
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