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2361
The potential biomarker value of soluble CD36 in the treatment of diabetic kidney disease: evidence from GLP-1 and insulin interventions
Published 2025-05-01“…Clinical parameters including sCD36, urinary albumin-to-creatinine ratio (UACR), lipid profile, glycemic markers, and islet function indices were assessed at baseline and post-treatment. …”
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2362
Significance of additional pulmonary blood flow between second and third stage in Fontan pathway
Published 2024-11-01“…Results Preoperative echocardiography showed no differences in ventricular function (good – 105[95%] vs. 65[98.5%]; reduced – 9[5%] vs 1[1.5%]; p = 0.07) or AV valve function (p = 0.78). …”
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2363
Research and application of image recognition-based identification for flesh browning of loquat fruits
Published 2025-02-01“…According to the membership function ranking by principal component analysis, the browning resistance of the 10 loquat resources from strong to weak was: Yanhong, Ruisui, Huangjinkuai, Zhongshudaxiang, Muluo Loquat, Zhongbai, Guifei, Sanyuebai, Baixuezao, Guofenben. …”
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2364
Maternal Outcomes Following Emergency Cesarean Delivery: Evaluating the Enhanced Recovery After Surgery Protocol in a Randomized Controlled Trial
Published 2025-06-01“…The ERAS group also had faster bowel function recovery and earlier breastfeeding initiation. …”
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2365
Research on Intelligent Networking Architecture for the Integrated Space-Terrestrial Networks
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2366
Effective implementation of ESG principles under technological sovereignty
Published 2024-01-01“…In the meantime, the sanctions pressure which began in 2014, compounded by pandemic restrictions and post-pandemic exacerbation, brought about a new way of revitalization for the development of the principles of “Environment”, “Society”, “Governance” - different from the previously accepted one in the global economy. …”
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2367
Low-complexity signal detection algorithm for the power splitting receiver scheme
Published 2024-04-01“…Firstly, considering the influence of antenna noise, post-processing noises, and power splitting factor, a splitting receiver architecture was designed, and a simplified two-dimensional received signal model was further established. …”
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2368
Image-Building of Chinese Motorcycle Enthusiasts on Chinese Social Media Douyin
Published 2024-01-01“…In the post-COVID era, the rise of domestic motorcycle culture and platforms like Douyin have given motorcycles stronger social communication attributes, reducing their function as mere tools. …”
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2369
Cardiac power output ratio: Novel survival predictor after percutaneous ventricular assist device in cardiogenic shock
Published 2024-12-01“…Such a proportional change of CPO over time, likely reflecting native heart function recovery, may help to guide management of CS patients post‐PVAD.…”
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2370
Urinary disorders in patients diagnosed with organic brain pathology
Published 2024-09-01“…To analyse the impaired function of lower urinary tracts in patients with organic brain pathology.Materials & methods. …”
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2371
Examining the Intersection of Educational Administration, Power, and Religion in Iran's Historical Social Context: A Bourdieusian Perspective
Published 2024-03-01“…Therefore, utilizing the method of document research and employing the thematic analysis technique aligned with the Bourne and Clark approach, as well as the Atrayd Sterling model, the social history of Iran was studied in two periods: pre-Islamic (Ancient Iran) and post-Islamic (up to the mid-Qajar period and modern educational developments). …”
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2372
Mathematical model for prediction of Tuberculosis in Nigeria using hybrid fractional differential equations and artificial neural network methods
Published 2025-06-01“…The data used for the analysis were obtained from the TB report by the World Health Organisation (WHO) TB Data Base, Nigeria Dash Board, from the years 2010–-2020. …”
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2373
Effects of a Kundalini Yoga programme on cardiorespiratory fitness and health-related quality of life in university students
Published 2024-12-01“…A repeated measures analysis assessed the time×group interaction effect with post-hoc analysis (alpha= .05). …”
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2374
Integrated omics revealed the altered colonic microenvironment after inhibition of peripheral serotonin synthesis by LP533401
Published 2024-12-01“…Abstract Gut‐derived 5‐hydroxytryptamine (5‐HT), known as serotonin, plays a crucial role in regulating gastrointestinal functions. However, the impact of disruptions in gut‐derived 5‐HT synthesis on the early gut microbiome and intestinal microenvironment remains unclear. …”
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2375
LncRNA XIST promoted the stability of TLR9 mRNA in a FUS-dependent manner to facilitate aerobic glycolysis and proliferation in Th17/CD4+T cells
Published 2022-05-01“…ObjectiveTo explore the expression and function of lncRNA XIST in Th17 cells in IgA nephropathy (IgAN) and examine the regulation of lncRNA XIST on TLR9 mRNA expression.MethodsCD4+T cells were isolated from peripheral blood mononuclear cells (PBMCs) and induced to differentiate into Th17 cells.XIST was over-expressed and silenced by plasmid transfection.Proliferation and apoptosis of Th17 cells with different levels of XIST expression were detected by flow cytometry and CCK-8 assay.Levels of XIST,TLR9 mRNA and protein were detected by quantitative reverse transcription-polymerase chain reaction (qRT-PCR) and Western blot.The effect of XIST on TLR9 expression was predicted by luciferase report analysis and TLR9 mRNA half-life detection.Potential RNA-binding proteins interacting with XIST were searched through Starbase database and detected by RNA immunoprecipitation and Western blot.GraphPad8.0 was utilized for statistical analysis and variables were expressed as average±SD.Student T test or one-way ANOVA was employed.ResultsXIST was distributed predominantly in cytoplasm.It hinted that XIST might be involved in post-transcriptional regulation.A down-regulation of lncRNA XIST expression promoted apoptosis and DNA damage and arrested cell proliferation by regulating TLR9.With an over-expression of lncRNA XIST,TLR9 expression spiked and XIST up-regulated the expression of TLR9 by promoting the stability of TLR9 mRNA.As an RNA-binding protein (RBP),FUS interacted with XIST and FUS antibodies could significantly enrich XIST transcripts.A down-regulation of lncRNA XIST expression had no effect on FUS protein expression.It suggested that XIST might affect FUS function rather than expression.It was further confirmed that a down-regulation of XIST significantly reduced FUS-TLR9 mRNA binding and FUS over-expression rescued a down-regulation and degradation of TLR9 mediated by si-XIST.ConclusionlncRNA XIST and TLR9 play a critical role in Th17 cell proliferation in IgAN through a FUS-mediated signaling pathway.This finding provides new therapeutic ideas for IgAN..…”
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2376
Effectiveness of Manual Myofascial Release versus Instrument assisted soft tissue Mobilization (IASTM) in patients with chronic neck pain - RCT
Published 2025-03-01“…Participants were assessed at the baseline and post assessment was done lastly after the 6th session. …”
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2377
The advantages of artificial intelligence-assisted total hip arthroplasty: A randomized controlled trial followed by 12 months
Published 2024-11-01“…The operation time for AI-assisted total hip arthroplasty was 104.32 ± 18.10 min, which was shorter than that of the traditional two-dimensional X-ray planning group (P < 0.05). At 3 months post-operation, the grade of Harris score for hip function in the AI planning group was significantly better than that in the traditional two-dimensional X-ray planning group (P < 0.05). …”
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2378
Exploration of phosphoproteomic association during epimorphic regeneration
Published 2025-02-01“…Understanding these precise modifications and their impact on protein function could shed light on the remarkable regenerative capacity of tissues, with potential implications for therapeutic interventions. …”
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2379
Influences of social support following hip-fracture surgery for older adults with cognitive impairment and their family caregivers
Published 2025-07-01“…Perceived social support was assessed one month post-discharge using the Medical Outcomes Study Social Support Survey (MOS-SSS) and categorized as good (score = 95) or poor (< 95). …”
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2380
Brain stimulation enhances dispositional mindfulness in PTSD: an exploratory sham-controlled rTMS trial
Published 2025-04-01“…Non-invasive repeated transcranial magnetic stimulation (rTMS) of the dorsolateral prefrontal cortex (DLPFC) has been shown to regulate mood and improve PTSD symptoms.MethodsThis is a retrospective chart analysis of data collected pre-treatment, post-treatment, and at three-month follow-up in a single-site, double-blind, sham-controlled trial of right DLPFC rTMS. 31 participants diagnosed with PTSD were recruited for this pilot study. …”
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