Collagenase injection versus limited fasciectomy surgery to treat Dupuytren’s contracture in adult patients in the UK: DISC, a non-inferiority RCT and economic evaluation by Joseph Dias, Puvan Tharmanathan, Catherine Arundel, Charlie Welch, Qi Wu, Paul Leighton, Maria Armaou, Belen Corbacho, Nick Johnson, Sophie James, John Cooke, Christopher Bainbridge, Michael Craigen, David Warwick, Samantha Brady, Lydia Flett, Judy Jones, Catherine Knowlson, Michelle Watson, Ada Keding, Catherine Hewitt, David Torgerson

“…There were no material changes in these results for any of the sensitivity or additional analyses undertaken. The primary analysis therefore shows that there is little evidence to support rejection of the hypothesis that collagenase is inferior to LF at 1 and 2 years post treatment. …”
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Glucocorticoid Insensitivity: Is It a Question of Time and Place? by Christopher Lambers, Michael Roth

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THE JUSTIFICATION OF THE EFFICIENCY OF FINANCIAL SUPPORT OF EDUCATION IN THE CONTEXT OF THE NATIONAL ECONOMY DEVELOPMENT by A. Vorontsova, T. A. Vasylieva, T. Mayboroda

“…In the conditions of formation of post-industrial social relations, there is a qualitative transformation of basic principles of functioning of both leading national economies and the world economy as a whole. …”
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FORMATION AND DEVELOPMENT OF THE SCIENTIFIC COMPONENT PROGRAM FOR THE TRAINING OF DOCTORS OF PHILOSOPHY IN THE FIELD OF POLITICAL SCIENCE AT V. N. KARAZIN KHARKIV NATIONAL UNIVER... by Victor Rubanov

“…So the tradition  of systemic and systemic-structural approaches to the study of political problems, was not only been formed and continued by leading professors and their students of the Soviet and post-Soviet periods of development of the Kharkiv School of Political Analysis, but also embedded in the logic, content and structure of the educational and scientific preparation programme of modern PhD in political science at the V. …”
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Early detection to improve outcome in people with undiagnosed psoriatic arthritis: the PROMPT research programme including RCT by Neil McHugh, Laura Bojke, Mel Brooke Turfrey, Rachel Charlton, Myka Ransom, Laura C Coates, Howard Collier, Claire Davies, Emma Dures, Philip Helliwell, Jana James, Anya Lissina, Vishnu B Madhok, Alison L Nightingale, Jonathan Packham, Catherine Smith, Eldon Spackman, Cerys Tassinari, William Tillett, Sarah T Brown

“…The primary objective of TUDOR was to determine whether the early detection of undiagnosed PsA in people with psoriasis by ES compared to SC improves outcome in physical function at 24 months post registration. Secondary objectives were to compare disease and impact of disease between people diagnosed with PsA in the ES and SC arms at 24 months post registration. …”
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Multi-Domain Environmental Quality of Indoor Mixed-Use Open Spaces and Insights into Healthy Living—A Quarantine Hotel Case Study by Han Wang, Wenjian Pan

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Decoding Mental States in Social Cognition: Insights from Explainable Artificial Intelligence on HCP fMRI Data by José Diogo Marques dos Santos, Luís Paulo Reis, José Paulo Marques dos Santos

“…Artificial neural networks (ANNs) have been used for classification tasks involving functional magnetic resonance imaging (fMRI), though typically focusing only on fractions of the brain in the analysis. …”
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Integrative GWAS and transcriptomics reveal GhAMT2 as a key regulator of cotton resistance to Verticillium wilt by Long Wang, Long Wang, Long Wang, Yonglin Yang, Jianghong Qin, Qifeng Ma, Kaikai Qiao, Shuli Fan, Yanying Qu

“…Functional validation through virus-induced gene silencing (VIGS) confirmed that silencing GhAMT2 compromised disease resistance. …”
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Brain connectomics markers for response prediction to transcranial magnetic stimulation in cocaine use disorder by Nayereh Ghazi, Eduardo A. Garza-Villarreal, Hamid Soltanian-Zadeh

“…Subsequently, 19 and 14 patients continued to an open-label maintenance phase of two weekly rTMS sessions for 3 and 6 months, respectively. Pre and post treatment resting-state brain functional connectivity as well as two clinical scores of craving were measured to predict the subsequent response to rTMS therapy. …”
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A first-in-human, prospective pilot trial of umbilical cord-derived mesenchymal stem cell eye drops therapy for patients with refractory non-Sjögren's and Sjögren's syndrome dry ey... by Di Zhang, Taige Chen, Qi Liang, Xuebing Feng, Jiaxuan Jiang, Zeying Chen, Yun Tang, Yiran Chu, Bin Wang, Kai Hu

“…Secondary assessments focused on the evaluation of lipid layer, meibomian gland function, and bulbar conjunctival redness. Safety was monitored by recording adverse events (AEs) throughout the study. …”
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A long-term nutritional assessment of maxillary cancer patients undergoing prosthodontic rehabilitation after surgery: A longitudinal study by Elangbam Merina Devi, Chanchal Gupta, K.P. Kochhar, Dheeraj Kumar Koli, Aditi Nanda, Veena Jain

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Power User Load Response Potential Assessment under Fuzzy-Rough Environment by Chaobo GUO, Yibo ZHANG, Hongjiong ZHANG, Kai MA, Lu CHEN

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Steroid dynamics in myalgic encephalomyelitis / chronic fatigue syndrome: a case-control study using ultra performance supercritical fluid chromatography tandem mass spectrometry by Natalie Thomas, S. J. Kumari A. Ubhayasekera, Christopher W. Armstrong, Katherine Huang, Jonas Bergquist

“…Abstract Background Myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS) is a multisystem disorder characterised by unrelenting fatigue, post-exertional malaise, and dysfunction across immune, nervous, metabolism, and endocrine systems. …”
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Severe interstitial lung disease risk prediction in anti-melanoma differentiation-associated protein 5 positive dermatomyositis: the STRAD-Ro52 model by Fei Xiao, Feilong Chen, DongSheng Li, Songyuan Zheng, Xiao Liang, Juan Wu, JunYuan Zhong, Xiangliang Tan, Rui Chen, Junqing Zhu, Shixian Chen, Juan Li

“…The STRAD parameters were significantly correlated with demographic, inflammatory, organ function and immunological indicators. Lasso logistic regression analysis identified the −699 to −650 HU lung tissue proportion (%V7) as the optimal parameter for predicting severe ILD and S6·%V7, and the distribution of %V7 in the mid lungs was the optimal space parameter. …”
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Birmingham Hip Resurfacing: a retrospective cohort study of clinical, biochemical, and radiological outcomes in a non-designer centre at minimum 15 years’ follow-up by Martin S. Davey, Conor Farrell, Conor Kilkenny, Conor Medlar, Niall P. McGoldrick, John F. Quinlan

“…The overall survivorship was 94.3% at 15 years post BHR, with an all-cause revision rate of 5.7%. …”
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Physical culture and sport in the context of social and cultural institutionality by Aminet Magametovna Siyukhova, Irina Anzaurovna Udzhukhu, Yuri Vladimirovich Manchenko, Inna Nikolaevna Guchetl

“…The novelty of the research consists in reconsidering the importance of physical education and sports in modern society as a result of increased commercialization and separation of their organizational forms into elite and mass types. The purpose of the analysis is aimed at the structural and functional determination of the institutionalism of physical culture and sports, identifying their commonality and differences, allowing to correlate them within the framework of a single type of physical culture as a non-institutional form of universal culture. …”
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Artistic features of neural networks: Image and video generation in the context of museum practice by Ivan V. Filippskiy

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Features of myocardial characteristics of patients with acute ST-segment elevation myocardial infarction with diabetes mellitus as assessed by contrast-enhanced cardiac magnetic re... by O. V. Stukalova, Yu. O. Shalaginova, R. M. Shakhnovich, A. G. Komarova, N. L. Lyakhova, S. K. Ternovoy, I. I. Staroverov

“…All patients underwent cardiac MRI with contrast, including myocardial T1 mapping, tissue analysis of left ventricular myocardium with determination of infarct zone, heterogeneous zone, edema zone, pre- and post-contrast T1 values, extracellular volume values of healthy myocardium and infarct zone.Results. …”
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Proteomics of left ventricular structure in the Multi‐Ethnic Study of Atherosclerosis by Tess E. Peterson, Joao A.C. Lima, Sanjiv J. Shah, David A. Bluemke, Alain G. Bertoni, Yongmei Liu, Debby Ngo, Vinithra Varadarajan, Josyf C. Mychaleckyj, Craig W. Johnson, Bruce M. Psaty, Clary B. Clish, Kent D. Taylor, Peter Durda, Russell P. Tracy, Robert E. Gerszten, Stephen S. Rich, Jerome I. Rotter, Wendy S. Post, James S. Pankow

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Pre-transplant residual diuresis and oxalic acid concentration influence kidney graft survival. by Gideon Post Hospers, Mirjam Laging, Wesley J Visser, Pedro Miranda Afonso, Jeroen Ghp Verhoeven, Ingrid Ram Mertens Zur Borg, Dennis A Hesselink, Anneke M E de Mik-van Egmond, Michiel G H Betjes, Madelon van Agteren, David Severs, Jacqueline van de Wetering, Robert Zietse, Michel J Vos, Ido P Kema, Marcia M L Kho, Marlies E J Reinders, Joke I Roodnat

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