Cardiometabolic Modulation by Semaglutide Contributes to Cardioprotection in Rats with Myocardial Infarction by Yan H, Yao W, Li Y, Li T, Song K, Yan P, Dang Y

“…Weight, blood glucose, and lipid profiles were analyzed. Cardiac function was evaluated via echocardiography. Histopathological assessment and immunohistochemical analysis were performed. …”
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Delayed atorvastatin delivery promotes recovery after experimental spinal cord injury by Samuel C. Buchl, Ha Neui Kim, Benjamin Hur, Whitney L. Simon, Monica R. Langley, Jaeyun Sung, Isobel A. Scarisbrick

“…Female C57BL/6J mice underwent moderate 0.25 ​mm lateral compression SCI and received daily atorvastatin (10 ​mg/kg) or vehicle-only injections from two weeks post-injury for four weeks. Sensorimotor functions were assessed using the Basso Mouse Scale (BMS), its subscore, and the inclined plane test. …”
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Environmental Consequences Of the Capital Relocation In the Republic Of Kazakhstan by Natalia A. Koldobskaya

“…The subject of this article is the ecological transformation in former and modern capitals of the Republic of Kazakhstan, which was affected not only by post-Soviet changes but also by the transfer of capital functions from Almaty to Nur-Sultan. …”
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Efficacy and safety of B/F/TAF in treatment-naïve and virologically suppressed people with HIV ≥ 50 years of age: integrated analysis from six phase 3 clinical trials by Cissy M. Kityo, Samir K. Gupta, Princy N. Kumar, Amy R. Weinberg, Bhumi Gandhi-Patel, Hui Liu, Jason T. Hindman, Jürgen K. Rockstroh

“…We assessed the efficacy and safety of bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) in people with HIV (PWH) ≥ 50 years of age across treatment-naïve and virologically suppressed cohorts over a long-term follow-up. Methods This post hoc analysis included participants ≥ 50 and < 50 years of age from six phase 3 trials of B/F/TAF, comprising 2 treatment-naïve studies and 4 virologically suppressed studies. …”
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Unraveling the mitochondrial genome of the medicinal Chinese motherwort (Leonurus japonicus, Lamiaceae): structural dynamics, organelle-to-nuclear gene transfer, and evolutionary i... by Xinyu Bai, Xinyu Bai, Tingting Zhu, Huiru Chen, Xiaoqun Wang, Jing Liu, Yuqing Feng, Yuqing Feng, Yanbo Huang, Joongku Lee, Goro Kokubugata, Zhechen Qi, Xiaoling Yan

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More Evidence that Surgical Intervention for Unstable Distal Radius Fracture in Elderly Does not Offer a Superior Patient Perceived Functional Advantage over Time Honored Conservat... by Raghavendra S Kulkarni, Sriram R Kulkarni

“…Despite wrist arthritis, the functional result is not different. A systematic review of the literature and meta-analysis comparing conservative treatment and surgical intervention found similar results. …”
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Clinical assessment and transcriptome analysis of host immune responses in a vaccination-challenge study using a glycoprotein G deletion mutant vaccine strain of infectious laryngo... by Gayathri Gopakumar, Mauricio J. C. Coppo, Mauricio J. C. Coppo, Andrés Diaz-Méndez, Carol A. Hartley, Joanne M. Devlin

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Enhanced Oligopeptide and Free Tryptophan Release from Chickpea and Lentil Proteins: A Comparative Study of Enzymatic Modification with Bromelain, Ficin, and Papain by Éva Domokos-Szabolcsy, Tarek Alshaal, Nevien Elhawat, Zoltán Kovács, László Kaszás, Áron Béni, Attila Kiss

“…Papain and bromelain treatments resulted in a significant release of oligopeptides and dipeptides. UHPLC analysis highlighted a marked post-hydrolysis increase in total free amino acids, with arginine, leucine, and lysine being the most abundant ones. …”
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The association of diabetes mellitus and routinely collected patient‐reported outcomes in patients with cancer. A real‐world cohort study by Dominik J. Ose, Emmanuel Adediran, Bayarmaa Mark, Krista Ocier, William A. Dunson JR, Cindy Turner, Belinda Taylor, Kim Svoboda, Andrew R. Post, Jennifer Leiser, Howard Colman, Cornelia M. Ulrich, Mia Hashibe

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Investigating shared risk variants and genetic etiology between Alzheimer’s disease and three stress-related psychiatric disorders: a large-scale genome-wide cross-trait analysis by Weijia Dang, Tianqi Hao, Ning Li, Hualin Zhang, Ziqi Li, Hongmei Yu, Yalu Wen, Deqiang Zheng, Long Liu

“…Association analysis based on subsets and cross-phenotype association revealed thirteen risk variants in six genes shared between AD and post-traumatic stress disorder; seven risk variants in four genes shared between AD and anxiety disorder; and 23 risk variants in four genes shared between AD and major depressive disorder. …”
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Parental BPA exposure disrupts offspring transcriptomic profiles and impairs embryonic lineage specification during zygotic genome activation by Yuequn Chen, Kusheng Wu, Wenlong Huang

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Case Report: A comprehensive digital workflow to enhance predictability and precision with fixed dental prostheses in the posterior region by Isabela Toser, Andrei-Bogdan Faur, Andrei-Bogdan Faur, Anca-Elena Anghel-Lorinți, Anca Jivănescu, Anca Jivănescu

“…While the design was sent to a dental laboratory for fabrication, the workflow demonstrated efficiency, minimal invasiveness, and a high degree of predictability in achieving both functional and aesthetic outcomes, mostly manageable in a chair-side manner. …”
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Gamma Knife stereotactic radiotherapy combined with tislelizumab as later-line therapy in pMMR/MSS/MSI-L metastatic colorectal cancer: a phase II trial analysis by Yiran Zhang, Hanyang Guan, Shijin Liu, Haoquan Li, Zili Bian, Jiashuai He, Zhan Zhao, Shenghui Qiu, Tianmu Mo, Xiangwei Zhang, Zuyang Chen, Hui Ding, Xiaoxu Zhao, Liang Wang, Yunlong Pan, Jinghua Pan

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Temporal profiling of host transcriptome highlights time- and tissue-dependent Interferon pathway activation in NNV-infected European sea bass by Luca Peruzza, Giulia Dalla Rovere, Serena Ferraresso, Rafaella Franch, Daniela Bertotto, Francesco Pascoli, Gaia Bacchin, Anna Toffan, Luca Bargelloni

“…Here, we report on a time-course transcriptome analysis of brain and head kidney in NNV-infected bass that integrated the statistical evidence of differential expression with the information on temporal profiles (i.e. 6, 12, 24, 48, and 72 h post-infection (hpi)) compared to mock-infected controls. …”
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Impact of spinal-hip types on gait patterns in patients with end-stage hip disease by Zhuyi Ma, Shengxing Fu, Xiangdong Wu, Kaiqi Cao, Hao Tang, Yixin Zhou

“…The study included 10 patients in each type (A, B, and C) and 10 healthy controls. Gait analysis was performed to evaluate the spatiotemporal and kinematic parameters, followed by the gait profile score (GPS) analysis. …”
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Teacher talk at three Colombian higher education institutions by Balcárcel Zambrano Gloria

“…The database comprises transcripts of over 16 hours of interaction recording during 15 lessons in 15 general EFL&#13; classrooms at the post-secondary level. The functions of teacher talk are analyzed by gathering data using the FLint system instrument adapted from Moskowitz (1971). …”
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Cisplatin-Induced Renal Failure Measured by Glomerular Filtration Rate (GFR) with ⁹⁹mTc-DTPA Scans in Cancer Patients: A Systematic Review and Meta-Analysis by Mansour M. Alqahtani

“…The findings underscore the nephrotoxic effects of cisplatin, a widely used chemotherapeutic agent, as demonstrated by the significant decline in GFR observed across multiple treatment cycles, and these findings were also supported by the findings of a meta-analysis that showed a significant (<i>p</i> < 0.01) difference between peri- and post-treatment GFR level with 37.06 (95% CI, 10.90–63.23) effect size and 96% heterogeneity. …”
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Research on Current Situation and Countermeasure of Chinese Primary Care Physicians&apos; Community Rehabilitation Service Ability by LIAN Lu, WANG Di, CHEN Jiaying, LIU Wu

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Analgesic efficacy and safety of erector spinae plane block versus serratus anterior plane block in breast surgery—a meta-analysis and systematic review of randomized controlled tr... by Samiullah Shaikh, Umm E Salma Shabbar Banatwala, Paranshi Desai, Muhammad Arham Khan, Rimsha Bint-e-Hina, Sidra Samad, Muhammad Hamza Sikandari, Ali Nawaz, Rana Ijaz, Shayan Asmat, Abeer Fatima, Harim Mirza, Noor Mahal Azam, Qurat Ul Ain Muhammad, Satesh Kumar, Mahima Khatri

“…Many undergoing breast surgery experience postoperative pain compromising their functionality and quality of life. While multiple pain management strategies are available, evidence comparing the erector spinae (ESPB) and serratus anterior plane blocks (SAPB) for improving post-surgical pain management in breast cancer surgery patients is limited. …”
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Phenotypic evaluation of worldwide germplasm of arugula (Eruca sativa Mill.) and identification of underlying latent factors contributing to phenotypic variation under indoor farmi... by Seam Choon Law, Ting Xiang Neik, Ethan Tze Cherng Lim, Adrian Ming Jern Lee, Yi Lin Lim, Wan Zu Tang, Shuang Song, Pei-Wen Ong, Sin Joe Ng, Fook Tim Chew

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