A Bioinformatic Approach for Molecular Characterization and Functional Annotation of an Uncharacterized Protein from <i>Vibrio cholerae</i> by Md. Yousuf, Abu Saim Mohammad Saikat, Md. Ekhlas Uddin

“…With inadequate water purification and sewage disposal systems, cholera poses a significant health threat in developing nations. …”
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SUMOylation substrate encoding genes as prognostic biomarkers in pancreatic ductal adenocarcinoma with functional assessment of SAF-B2 by Xiangjun Wang, Chuanxin Yang, Yangming Liu, Jian Wang

“…BackgroundPancreatic ductal adenocarcinoma (PDAC) is highly malignant with a poor prognosis, posing significant clinical challenges. SUMOylation, a reversible post-translational modification, plays a critical role in tumor progression, yet its prognostic significance in PDAC remains unclear.MethodsWe assessed SUMOylation expression patterns and function in PDAC using Western blot and the SUMOylation inhibitor TAK-981. …”
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Underground guardians: how collagen and chitin amendments shape soil microbiome structure and function for Meloidogyne enterolobii control by Josephine M. Pasche, Roshni Sawlani, Victor Hugo Buttrós, Johan Desaeger, Karen A. Garrett, Samuel J. Martins

“…Abstract Background The emergence of the guava root-knot nematode (Meloidogyne enterolobii) poses a significant threat to tomato yields globally. …”
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Effect of Serum Lipid Profile and Renal Functions during Pregnancy and its associated diseases in Sulaimanyah / Kurdistan Region by Azad Mohammed Aziz Ahmed, Amjad Mahmood Qadir, Jamal Kareem Shakor, Musa M. Zorab

“… Background and Objective: The physiological function of the kidneys poses significant challenges during pregnancy, impacting maternal and fetal health. …”
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A Priestia megaterium MF3 with high-efficiency zearalenone degradation: functional genomic insights and mechanistic exploration by Di Meng, Kai-Zhong Xu, Kai-Zhong Xu, Hong-Jian Hou, Jin-Bin Liu, Dan-Dan Deng, Jun-Min Li, Ya-Kun Fang, Xiao-Qin Zhu, Dong-Li Pei

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GC vitamin D-binding protein gene functional genetic variants and gestational diabetes mellitus risk and prediction by Ruiqi Li, Zhihua Wang, Mengyan Xiang, Qiulian Liang, Shiya Qin, Lijie Nie, Guangying Qi, Xiangyuan Yu

“…Abstract Gestational diabetes mellitus (GDM) is a pregnancy-complicated disease that poses risks to maternal and infant health. However, its etiology has not yet been elucidated. …”
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Optimized Design and Deep Vision-Based Operation Control of a Multi-Functional Robotic Gripper for an Automatic Loading System by Yaohui Wang, Sheng Guo, Jinliang Zhang, Hongbo Ding, Bo Zhang, Ao Cao, Xiaohu Sun, Guangxin Zhang, Shihe Tian, Yongxu Chen, Jixuan Ma, Guangrong Chen

“…Methodologically, we first developed three gripper prototypes, selecting the optimal design (30° angle between the gripper and container side) through workspace and interference analysis. A deep vision-based recognition system, enhanced by an improved YOLOv5 algorithm and multi-feature fusion, was employed for real-time object detection and pose estimation. …”
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Rapid enrichment and SERS detection of fenitrothion and methyl parathion in vegetable and fruit juices using a dual-functionalized microneedle by Mengping Zhang, Hui Pan, Yafen Zeng, Xiao Meng, Wenwen Chen, Meng Jin, Hua Shao, Haiyan Wei, Cuijuan Wang

“…This study presents an ultrafast enrichment and SERS detection approach, achieving rapid analysis of fenitrothion and methyl parathion in vegetable and fruit juices using a dual-functionalized microneedle. …”
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Identification of key genes associated with cellular aging and mitochondria in acute myocardial infarction by Dehong Chen, Lingling Yao, Ke Mo, Linan Li, Zhiheng Liu, Zhengyuan Xia, Hanlin Ding

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Possibilities of Using Artificial Intelligence in Security Analysis by Maciej Norbert Ciesielski

“…In total, out of twelve features/variables that make up analytical imagination, artificial intelligence already functions efficiently (or will function efficiently soon) in practically all of them.…”
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Association between wooden toy engagement and cognitive function among Chinese older adults: a cross-sectional study by Hanqian Wang, Qiuping Cheng, Ping Mei, Mengni Cui, Qunlong Wang, Lu Li, Lu Li

“…BackgroundThe rising prevalence of cognitive impairment among older adults poses a significant public health challenge. While wooden toys are traditionally regarded as tools for cognitive stimulation, research on their potential relationship with cognitive function in older adults remains limited. …”
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Dioctylsulfosuccinate Functionalized NiAl-Layered Double Hydroxide for Sensitive Fenuron Electroanalysis Using a Carbon Paste Electrode by Aude Peggy Kameni Wendji, Herve Leclerc Tcheumi, Ignas Kenfack Tonle, Emmanuel Ngameni

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Dual functions of silibinin in attenuating aortic dissection via regulating iron homeostasis and endoplasmic reticulum stress against ferroptosis by Zhen Qi, Qiu-Guo Wang, Meng-Xi Huang, Yi-Fan Zeng, Jing-Yu Li, Zhi-Cheng Duan, Ling Tan, Hao Tang

“…Abstract Aortic dissection (AD) poses a significant threat to cardiovascular health globally, yet its underlying mechanisms remain elusive. …”
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Merging π-molecular functions achieved through homogeneous liquid-liquid blending of solvent-free alkyl-π liquids by Zhenfeng Guo, Chengjun Pan, Akira Shinohara, Takashi Nakanishi

“…In this study, we propose a liquid-liquid blending strategy that enables the precise and homogeneous merge of π-functions of alkyl π-liquids. Rheological analysis was used to evaluate miscibility between alkyl π-liquids. …”
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Multi-frequency EEG and multi-functional connectivity graph convolutional network based detection method of patients with Alzheimer’s disease by Yujian Liu, Libing An, Haiqiang Yang, Shuzhi Sam Ge

“…The method conducts multi-frequency analysis of power spectral density (PSD) features across five EEG frequency bands (Delta, Theta, Alpha, Beta, Gamma) and constructs two functional connectivity networks based on mutual information and Pearson correlation coefficients. …”
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Transposon mediated functional genomic screening for BRAF inhibitor resistance reveals convergent Hippo and MAPK pathway activation events by Li Chen, Iulian Pruteanu-Malinici, Anahita Dastur, Xunqin Yin, Dennie Frederick, Ruslan I. Sadreyev, Cyril H. Benes

“…Although several forward genetic screens performed in the same context have identified a broad range of resistance genes that poorly overlap, an integrative analysis revealed a much smaller functional diversity of resistance mechanisms, including reactivation of the MAPK pathway, PI3K-AKT pathway, and Hippo pathway, suggesting that a relatively small number of therapeutic strategies might overcome resistance manifested by a large gene set. …”
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Optimizing Edible Sorghum Bowls: Effects of Roasting and Edible Flower Powder Enhancement on Technological, Nutritional, Antioxidant, and Functional Properties by Devatha Manivel, Raajeswari Paramasivam, Swarup Roy

“…The widespread reliance on single-use plastics (SUPs) has fostered a global throwaway culture, especially in the food packaging industry, where convenience and low cost have driven their adoption, posing serious environmental threats, particularly to marine ecosystems and biodiversity. …”
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Emergence of blaKPC-2-carrying megaplasmid in carbapenem-resistant Pseudomonas aeruginosa ST1076: Genomic and functional insights by Jing Chen, Weidong Zhu, Chen Lin, Zhen Li, Haowei Ye, Danfeng Lou

“…Objective: Carbapenem-resistant Pseudomonas aeruginosa (CRPA) poses a critical challenge to clinical treatment due to its multidrug resistance and genomic plasticity. …”
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Predicting Functional Decline in Geriatric Abdominal Surgery Patients: Unveiling Incidence, Risk Factors, and Innovative Predictive Models in Thailand by Poungkaew Thitisakulchai, Arunotai Siriussawakul, Sunit Jarungjitaree, Nipaporn Sangarunakul, Piyapat Dajpratham

“… Objective: Surgery poses significant challenges for older adults, potentially leading to functional decline. …”
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Functional characterization of cutinase genes NsCut1-NsCut4 in Neostagonosporella sichuanensis and their effects on fishscale bamboo by Mengyao Lu, Mengyao Lu, Fang Liang, Fang Liang, Lijuan Liu, Lijuan Liu, Yanji Yin, Yanji Yin, Dongxin Xu, Dongxin Xu, Huan Zou, Huan Zou, Yinggao Liu, Yinggao Liu, Chunlin Yang, Chunlin Yang

“…Based on genomic analysis, four cutinase genes, NsCut1–NsCut4, were identified, cloned, and functionally validated. …”
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