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Complex immunotoxic effects of T-2 Toxin on the murine spleen and thymus: Oxidative damage, inflammasomes, apoptosis, and immunosuppression
Published 2025-01-01“…T-2 toxin (T-2), a highly stable and toxic mycotoxin, poses a significant public health risk as an inevitable environmental pollutant. …”
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Structurally engineered monolithic catalyst for enhanced sunlight-driven degradation of ciprofloxacin in contaminated water systems
Published 2025-07-01“…The hexagonal ZnO nanorods, coupled with cubic silver nanoparticles embedded within graphene nanosheets, provided superior physicochemical and electrochemical properties. Morphological and functional analysis exhibited evidence of metallic silver formation. …”
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In Silico Evaluation of Terpene Interactions with Inflammatory Enzymes: A Blind Docking Study Targeting Arachidonic Acid Metabolism
Published 2025-07-01“…Blind rigid-body molecular docking is performed using AutoDock 4.2 and the Lamarckian Genetic Algorithm, with 100 runs per ligand–enzyme pair and the energy-based selection of optimal poses. The analysis includes binding energy (ΔG), inhibition constants (Ki), root-mean-square deviation (RMSD), and residue-level interactions. …”
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Oat and Forage Pea Mixed Sowing Improves Soil Chemical Fertility and Fresh and Dry Mass Yield in Light Saline–Alkali Land: Preliminary Results
Published 2025-01-01“…Saline–alkali land is widely distributed worldwide, and poses significant challenges to agricultural productivity and ecological restoration, particularly in the Qaidam Basin. …”
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Isolated iridium oxide sites on modified carbon nitride for photoreforming of plastic derivatives
Published 2025-03-01“…Abstract The rising concentration of plastics due to extensive disposal and inefficient recycling of plastic waste poses an imminent and critical threat to the environment and ecological systems. …”
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Brown alga Sargassum wightii derived bioactive compound as potential anti-cancerous agent and molecular docking insights on Hep-2, THP-1 and Cervical cancer cell lines
Published 2025-07-01“…Cervical cancer remains a major cause of mortality among women worldwide, with cisplatin resistance posing a critical therapeutic challenge. In this study, Naringenin, a flavonoid compound, was isolated and purified from the brown alga Sargassum wightii. …”
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Model systems for emulating human tissue and physiology in psychiatric research
Published 2025-04-01“…The modeling of psychiatric disorders poses significant challenges due to the complex nature of these conditions, which encompass a range of neuropsychiatric diseases such as autism spectrum disorder (ASD), schizophrenia (SCZ), bipolar disorder (BD), post-traumatic stress disorder (PTSD), anxiety disorder (AD) and depression. …”
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1369
Effects of Ammonia Stress on Liver Tissue Structure, Enzyme Activities, and Metabolome of Juvenile Largemouth Bass <i>Micropterus salmoides</i>
Published 2024-11-01“…An increase in ammonia concentration exacerbated liver tissue damage. Metabolome analysis further unveiled perturbations in liver metabolites of <i>Micropterus salmoides</i> exposed to ammonia, with Ala-His emerging as a potentially pivotal functional substance under chronic stress. …”
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Effective adsorptive removal of triclosan from water using bio-nanocomposite hydrogel beads
Published 2025-04-01“…The surface charge, morphology, thermal stability, crystallinity, and functional groups of NaAlg/MnS bio-nanocomposite hydrogel beads were characterised by SEM equipped with EDX, TEM, Thermogravimetric analysis, FTIR, XRD, and zeta sizer (mV).Results and discussionsThe experimental results demonstrated that incorporating 0.02–0.2 g of MnS NPs in the bio-nanocomposite hydrogels led to enhanced mechanical structure, porosity, and swelling ability for the adsorption of triclosan compared to pristine NaAlg hydrogel. …”
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1371
Formation control method for multiple flight vehicles based on adaptive dynamic programming
Published 2025-05-01“…However, controlling such systems poses considerable challenges because of their nonlinear dynamics, environmental interference, and uncertainties in system models. …”
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1372
Comparing acute versus AIDS ART initiation on HIV-1 integration sites and clonal expansion
Published 2025-01-01“…The early intervention helps slow the progress of clonal expansion of infected cells, reducing the formation of stable and persistent reservoirs, and ultimately posing fewer barriers to achieving a functional cure.…”
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1373
The reduction in genetic quality of seeds resulting from self-pollination acts as a pivotal factor limiting the regeneration of the endangered plant Tetracentron sinense Oliv
Published 2025-08-01“…They also showed lower survival rates and higher mortality rates than cross-pollinated seedlings. Analysis of the mortality density and hazard rate functions revealed a significant mortality peak and the highest failure risk at the two-month stage in T. sinense seedlings, indicating potential challenges during this period. …”
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Environmental impact of car wash services by performing life cycle perspective
Published 2025-01-01“…Chemical runoff, including detergents, surfactants, and heavy metals, poses a significant threat to aquatic ecosystems, especially in areas with inadequate wastewater treatment infrastructure. …”
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Network Pharmacology and Metabolomics Reveal Anti-Ferroptotic Effects of Curcumin in Acute Kidney Injury
Published 2024-12-01“…Xi Liu,1,2,* Yu Zhou,3,* Ziyi Lu,1 Fenglin Yang,1 Yizhi Wang,4 Sijin Zhang,5 Jinwen Zhang,1 Hong Zou,6 Min Lin1 1Research Center of Innovation, Entrepreneurship, Minjiang University, Fuzhou, 350100, People’s Republic of China; 2Key Laboratory for Chemical Biology of Fujian Province, MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, 361005, People’s Republic of China; 3Cancer Research Center & Jiangxi Engineering Research Center for Translational Cancer Technology, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, 330004, People’s Republic of China; 4School of Intelligent Science and Control Engineering, Jinling Institute of Technology, Nanjing, 211169, People’s Republic of China; 5Guangdong Cardiovascular Institute, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510000, People’s Republic of China; 6Physical Education Department, Xiamen University, Xiamen, 361005, People’s Republic of China*These authors contributed equally to this workCorrespondence: Min Lin; Hong Zou, Email minlin@mju.edu.cn; zou_hong0402@126.comIntroduction: Acute kidney injury (AKI) is linked to high rates of mortality and morbidity worldwide thereby posing a major public health problem. …”
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Biosynthesis of Two Types of Exogenous Antigenic Polysaccharides in a Single <i>Escherichia coli</i> Chassis Cell
Published 2025-05-01“…Whole-cell proteomic profiling followed by MFUZZ clustering and Gene Ontology analysis revealed that core biosynthetic genes were grouped into two functional clusters. …”
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A Novel Metallo‐β‐Lactamase AMM‐1 From Alteromonas mangrovi Reveals a Cryptic Environmental Reservoir of Carbapenem Resistance
Published 2025-07-01“…ABSTRACT Carbapenem resistance driven by metallo‐β‐lactamases (MBLs) poses a formidable global challenge as these enzymes can degrade a wide range of β‐lactam antibiotics, including last‐line carbapenems. …”
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Optimizing Energy and Spectral Efficiency in Mobile Networks: A Comprehensive Energy Sustainability Framework for Network Operators
Published 2025-01-01“…Notably, the implemented ML and XAI model achieved an F1-Score of 0.78 for 5G scenarios and 0.83 for 4G scenarios in predicting the Energy Sustainability Class, relying on a reduced set of indicators encompassing the most influential factors. An additional analysis, based on domain expertise, provided evidence of potential causal relationships between the class and observed variables involving channel quality, Multiple Input Multiple Output (MIMO) utilisation, network topology and energy-saving functionalities. …”
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