The T3SS structural and effector genes of Chlamydia trachomatis are expressed in distinct phenotypic cell forms by Nicole A. Grieshaber, Cody Appa, Megan Ward, Alorah Grossman, Sean McCormik, Brendan S. Grieshaber, Travis Chiarelli, Hong Yang, Anders Omsland, Scott S. Grieshaber

“…Moreover, we show that the genes for the type III secretion system (T3SS) were cell type restricted, suggesting defined functional roles for the T3SS in specific cell forms.ImportanceChlamydia trachomatis, a sexually transmitted bacterial infection, poses a significant global health threat, causing over 100 million infections annually and leading to complications like ectopic pregnancy and infertility. …”
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Predicting Social Frailty in Older Adults Using Fitbit-Derived Circadian and Heart Rate Biomarkers: Cross-Sectional Study by Hiroki Maekawa, Yu Kume

“… BackgroundSocial frailty poses a potential risk even for relatively healthy older adults, necessitating development of early detection and prevention strategies. …”
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Direct RNA sequencing reveals chicken post-transcriptional modifications in response to Campylobacter jejuni inoculation by Yanan Zhao, Yuanmei Wang, Yanru Ren, Long Liu, Tianyi Wang, Liying Liu, Xianyao Li

“…The transcripts containing m6A/m5C modifications displayed higher expression levels and shorter poly(A) tails than those without modifications. Functional analysis of these modules including differentially expressed transcripts (DETs), transcripts with differentially significant poly(A) tail length, m5C modified DETs, and m6A modified DETs showed that the negative regulation of interferon-beta production was enriched (P < 0.05). …”
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Integral approach to organelle profiling in human iPSC-derived cardiomyocytes enhances in vitro cardiac safety classification of known cardiotoxic compounds by Brigitta R. Szabo, Brigitta R. Szabo, Jeroen Stein, Anna Savchenko, Thomas Hutschalik, Thomas Hutschalik, Filip Van Nieuwerburgh, Tim Meese, Georgios Kosmidis, Paul G. A. Volders, Elena Matsa, Elena Matsa, Elena Matsa, Elena Matsa

“…IntroductionEfficient preclinical prediction of cardiovascular side effects poses a pivotal challenge for the pharmaceutical industry. …”
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Geography, Antimicrobial Resistance, and Genomics of <i>Salmonella enterica</i> (Serotypes Newport and Anatum) from Meat in Mexico (2021–2023) by Eduardo Canek Reynoso, Enrique Jesús Delgado-Suárez, Cindy Fabiola Hernández-Pérez, Yaselda Chavarin-Pineda, Elizabeth Ernestina Godoy-Lozano, Geny Fierros-Zárate, Omar Alejandro Aguilar-Vera, Santiago Castillo-Ramírez, Luz del Carmen Sierra Gómez-Pedroso, Luisa María Sánchez-Zamorano

“…Considering unique genes, <i>Salmonella</i> Anatum and Newport showed a notorious abundance of genes with functions related to replication, recombination, and repair. …”
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The impact of playing tennis on the organ of vision - threats, benefits and prevention of the organ of vision by Dominik Rabstein, Piotr Gościniewicz, Hanna Porwolik, Agata Porwolik, Patrycja Pabis, Agnieszka Porwolik, Magdalena Bodera, Radosław Szydłowski

“…On the other hand, the sport also poses risks such as eye strain and mechanical injuries, including corneal and retinal damage. …”
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Information-Reduction Ability Assessment in the Context of Complex Problem-Solving by Xiaoxuan Bu, Huijia Zheng, Xuetao Tian, Fang Luo

“…., “information reduction”, is becoming more crucial to daily functioning. However, the fact that information reduction is most prominent in complex situations poses challenges for measuring and quantifying this ability. …”
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Demonstration of Smart Railway Level Crossing Design and Validation Using Data from Metro Rail, South Africa by D.C. Tshaai, A.K. Mishra, Jan. Pidanic

“…Long waiting time at railway level crossings poses a risk on the safety and affects capacity of rail and road traffic. …”
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Deconstruction as a Research Strategy for Discourse Studies: An Aporetic and Iterable Model for Opening Discourses by Elizabeth Deborah Martínez Aguilar, Sjors Witjes, René ten Bos

“…Nevertheless, deconstruction must be applied to exist, posing an inherent paradox. Although existing scholarships have proposed various ways to apply deconstruction, many either fail to align with it or are too vague in outlining practical applications. …”
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Pérou : le rêve de l’Etat-nation des intellectuels de la génération de 1900 by Patricia Salinas Desmond

“…Some of them, besides, have taken part in a partial modernization of the civil service and the functioning of the state. Although they did not realize their dream, the questions they posed a century ago are still relevant.…”
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A DFT insight into the potential of cycloparaphenylenes as efficient sensors for detecting Paracetamol by Wael A. Mahdi, Adel Alhowyan, Ahmad J. Obaidullah

“…Abstract Paracetamol (PCT) frequently contaminates natural water sources, posing potential risks to both human health and ecosystems. …”
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Efficient discovery of frequently co-occurring mutations in a sequence database with matrix factorization. by Michael Robert Kolar, Valerie Kobzarenko, Debasis Mitra

“…This analysis underscores the significant role of identified CMPs in understanding the evolutionary trajectory. …”
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Enhancing Privacy While Preserving Context in Text Transformations by Large Language Models by Tymon Lesław Żarski, Artur Janicki

“…We developed a conceptual solution that enhances user privacy by identifying and anonymizing named entity classes representing sensitive data while maintaining the original context by swapping source entities for functional data. Our approach utilizes natural language processing methods, combining machine learning tools such as MITIE and spaCy with rule-based text analysis. …”
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Not Everyone Will Be Taken into the Future? The Role of Forecasting in International Relations Theory by I. А. Istomin

“…In this sense, reluctance to test their logical inferences with predictions exemplified by scholars poses a barrier to the development of IR studies.…”
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Optimization of Risk and Return Using Fuzzy Multiobjective Linear Programming by Darsha Panwar, Manoj Jha, Namita Srivastava

“…Stock selection poses a challenge for both the investor and the finance researcher. …”
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Digital Transformation of Business Analytical Processes by O. E. Mikhnenko

“…Current development and management of economic activity is largely associated with the implementation of the concept of the digital economy, which poses new challenges for business intelligence. The set of tasks is formed in order to develop business intelligence so that it matches the improved management of economic subjects, and to ensure the quality of business processes when digital technologies are introduced. …”
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Prediction of potential drug targets and key inhibitors (ZINC67974679, ZINC67982856, and ZINC05668040) against Rickettsia felis using integrated computational approaches by Sudais Rahman, Hsien Liu, Mohibuallah Shah, Mashal M. Almutairi, Iram Liaqat, Tetsuya Tanaka, Chien-Chin Chen, Chien-Chin Chen, Chien-Chin Chen, Chien-Chin Chen, Abdulaziz Alouffi, Abid Ali

“…Rickettsia felis, responsible for flea-borne spotted fever, is a rising zoonotic pathogen posing an increasing global threat due to its expanding geographical distribution. …”
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Mutualism Disruption Threatens Global Plant Biodiversity: A Systematic Review. by Clare E Aslan, Erika S Zavaleta, Bernie Tershy, Donald Croll

“…Conservation measures with explicit focus on mutualistic functions could be necessary to bolster populations of widowed species and maintain ecosystem functions.…”
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Integrating AlphaFold2 models and clinical data to improve the assessment of Short Linear Motifs (SLiMs) and their variants' pathogenicity. by Franco Gino Brunello, Lorenzo Erra, Juan Nicola, Marcelo Adrián Martí

“…In our previous work, we demonstrated that integrating sequence variant information with structural analysis can enhance the prediction of true functional SLiMs while simultaneously generating tolerance matrices that indicate whether each of the 19 possible single amino acid substitutions (SASs) is tolerated. …”
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Design and Application of GISC Beijing Global Cache by Gu Wenjing, Guo Ping, Zhang Laien, Xue Lei, Han Xinqiang, Gao Feng, He Wenchun, Wang Huaile, Wang Peng, Wang Bo

“…The global data cache's overall architecture is introduced, including its core functionalities and the underlying technical implementation. …”
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