Experimental evaluation of timing and preference of surgical ıntervention for crush syndrome in disaster scenarios: fasciotomy or amputation? A rat model study by Şehmuz Kaya, Yunus Can Ünal, Necip Güven, Abdulrahim Dündar, Ömer Faruk Keleş, Yıldıray Başbuğan

“…Common in disasters like earthquakes, it poses life-threatening risks, including acute renal failure, hyperkalemia, and metabolic acidosis. …”
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Relationship Between Body Mass Index and Low Skeletal Muscle Mass in Adults Based on NHANES 2011–2018 by Rong-Zhen Xie, Xu-Song Li, Fang-Di Zha, Guo-Qing Li, Wei-Qiang Zhao, Yu-Feng Liang, Jie-Feng Huang

“…Abstract Sarcopenia, a syndrome characterized by declining muscle mass and function, is associated with various adverse health outcomes. …”
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Fucoidan Alleviates Porcine Epidemic Diarrhea Virus-Induced Intestinal Damage in Piglets by Enhancing Antioxidant Capacity and Modulating Arginine Metabolism by Qian Zhang, Maojing Wang, Zhonghua Li, Di Zhao, Yongqing Hou, Tao Wu

“…Porcine epidemic diarrhea virus (PEDV) causes severe intestinal damage, posing significant threats to the swine industry. …”
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Hepatic basidiobolomycosis in a 2-year-old child: A case report by Ahmed Ateik, Saif Ghabisha, Ali Almutamaiz, Amar Almutawakel, Azza Mohamed, Faisal Ahmed

“…Hepatic basidiobolomycosis can mimic hepatic malignancies, posing a diagnostic and therapeutic challenge. Case presentation: A 2-year-old male was referred to us with a two-month history of abdominal pain and a right upper quadrant abdominal mass. …”
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IndoHerb: Indonesia medicinal plants recognition using transfer learning and deep learning by Muhammad Salman Ikrar Musyaffa, Novanto Yudistira, Muhammad Arif Rahman, Ahmad Hoirul Basori, Andi Besse Firdausiah Mansur, Jati Batoro

“…However, the dwindling recog-nition of herbal plants due to modernization poses a significant challenge in preserving this valuable heritage. …”
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Impact of multimorbidity on household expenditure in China: evidence from the China health and retirement longitudinal study by Mengqian Ouyang, Bowen Liu, Zhining Qiu, Wang Liao, Tao Chen

“…Abstract Background Multimorbidity poses a significant global economic burden, profoundly affecting individuals’ standard of living and leading to substantial increases in healthcare expenditures. …”
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Staphylococcus aureus-specific TIGIT+ Treg are present in the blood of healthy subjects – a hurdle for vaccination? by Jonah Clegg, Jonah Clegg, Malgorzata E. Mnich, Malgorzata E. Mnich, Alberto Carignano, Giovanni Cova, Simona Tavarini, Chiara Sammicheli, Bruna Clemente, Megan Smith, Megan Smith, Emilio Siena, Monia Bardelli, Michela Brazzoli, Fabio Bagnoli, Rachel M. McLoughlin, Elisabetta Soldaini

“…Using an activation induced marker assay to sort for S. aureus-specific CD4+ T cells in an effector function-independent manner, single cell transcriptomic analysis was conducted. …”
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Identification of Host–Protein Interaction Network of Canine Parvovirus Capsid Protein VP2 in F81 Cells by Hongzhuan Zhou, Huanhuan Zhang, Xia Su, Fuzhou Xu, Bing Xiao, Jin Zhang, Qi Qi, Lulu Lin, Kaidi Cui, Qinqin Li, Songping Li, Bing Yang

“…Canine Parvovirus (CPV) is a highly contagious virus that causes severe hemorrhagic enteritis and myocarditis, posing a major threat to the life and health of dogs. …”
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Management of recurrent aggressive vertebral hemangiomas: a comparative study of piecemeal intralesional spondylectomy and modified total en bloc spondylectomy by Dongjie Jiang, Zihuan Zhou, Qi Zhang, Shaohui He, Haitao Sun, Xiaopan Cai, Tielong Liu, Xinghai Yang, Haifeng Wei, Jianru Xiao

“…Abstract Background The management of recurrent aggressive vertebral hemangiomas (AVHs) with neurological deficits poses a challenge due to their profuse vascularization and propensity for recurrence. …”
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Lanthanum oxide nanoparticles induce AHR-mediated hepatotoxicity in zebrafish via oxidative stress and metabolic dysregulation by Jin-Xia Wang, Yiyun Liu, Yuan Ding, Bao-Fu Zhang, Yan-Ling Liao, Si-Jia Zuo, Qin-Hong Zhou, Yan Li, De-Sheng Pei

“…Exposure to La2O3 NPs triggered reactive oxygen species (ROS) overload in the liver of larvae, provoking oxidative damage and hepatocyte apoptosis. Transcriptomic analysis revealed altered expression of genes critical for liver function, including cytochrome P450 enzymes, implicating activation of the aryl hydrocarbon receptor (ahr) signaling pathway as a key mechanistic driver. …”
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Dasatinib demonstrates efficacy in organoid derived paclitaxel-resistant Trp53/Cdh1-deficient mouse gastric adenocarcinoma with peritoneal metastasis by Wenshuai Liu, Lingmeng Li, Leilei Guo, Haojie Li, Zhaoqing Tang, Xuefei Wang, Liyu Huang, Yihong Sun

“…Abstract Gastric cancer peritoneal metastasis (GCPM) typically indicates a poor clinical prognosis and is frequently observed in diffuse gastric cancer (GC) patients with CDH1 loss of function. GCPM characterized for its aggressiveness and resistance to chemotherapy, most notably paclitaxel (PTX), poses significant treatment challenges. …”
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Whole exon screening of SLC2A4 gene and the association of rs5435 with type 2 diabetes in a Bangladeshi case-control study by Mohammad Mamunur Rashid, Mohammad Sayem, Maisha Adiba, Abdullah Al Saba, A.H.M. Nurun Nabi, Tahirah Yasmin

“…Additionally, in silico analysis revealed that the rs5435 variant introduces an additional loop in the mRNA secondary structure, which is energetically less stable and therefore may interfere with the protein’s biological function and play a role in the pathogenesis of T2D. …”
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Deciphering the causal landscape: genetic insights into sporadic vestibular schwannoma risk factors through Mendelian Randomization by Yuyang Liu, Hui Feng, Hengchao Ma, Jing Li, Yang Yu, Hua Zhao, Xiaoguang Wang, Yun Li, Jun Zhang, Qi Liu

“…Abstract Background Sporadic vestibular schwannoma, a benign tumor affecting the vestibulocochlear nerve, poses significant health challenges due to its impact on hearing, balance, and facial nerve function. …”
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Coat Proteins of the Novel Victoriviruses FaVV1 and FaVV2 Suppress Sexual Reproduction and Virulence in the Pathogen of Fusarium Head Blight by Shulin Cao, Xiaoyue Yang, Lele Xia, Xing Zhang, Haiyan Sun, Yuanyu Deng, Yan Shu, Aixiang Zhang, Huaigu Chen, Wei Li

“…Fusarium head blight (FHB), a disease inflicted by <i>Fusarium graminearum</i> and <i>F. asiaticum</i>, poses a growing threat to wheat in China, particularly in the face of climate change and evolving agricultural practices. …”
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GATA1-mediated macrophage polarization via TrkB/cGMP–PKG signaling pathway to promote the development of preeclampsia by Wushan Li, Fei Hou, Di Cheng, Fengchun Gao, Jin Wang, Baoxia Cui

“…Abstract Background Preeclampsia (PE) is a severe pregnancy complication characterized by hypertension and proteinuria. PE poses a substantial threat to the health of both mothers and fetuses, and currently, there is no definitive treatment available. …”
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Exploration of plasma exosomal miR-122-5p and its related targets KNG1 and C3 in the diagnosis of drug-resistant tuberculosis by Xinyi Yao, Lahong Zhang

“…Abstract Drug-resistant tuberculosis (DR-TB) poses significant challenges not only to public health but also imposes substantial psychological and economic burdens on individuals and their families. …”
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Echocardiographic diagnosis of interarterial AAOCA in children: a framework integrating anatomical landmarks and systolic dysfunction for risk assessment by Rui Hu, Xuming Mo, Shanliang Zhu, Jun Chen, Ying Tang, Yumei Xu

“…Abstract Background Anomalous aortic origin of coronary arteries (AAOCA) with interarterial course poses life-threatening risks in pediatric patients, yet standardized preoperative imaging protocols remain limited. …”
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Postgraduate training in cardiology in Sudan during wartime: a story of perseverance and resilience by Nawal Elkurdufani, Salah Mohamed, Abdelbagi Ali, Mohamed Elmakki Ahmed

“…Free accommodation was offered to trainees, notwithstanding the challenges posed by inflation and the mass influx of internally displaced people.Despite the war conditions, the Cardiology Council Committee continued to function and meet remotely, addressing emerging challenges and resolving issues. …”
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Thyroid storm during the recovery phase after non-thyroid surgery in a hyperthyroid patient: a case report and literature review by Jiyu Zeng, Ting Yang, Li Wu

“…Although the risk is well-documented in thyroid surgeries, perioperative thyroid storm following non-thyroid procedures is exceedingly rare, posing diagnostic and therapeutic challenges. This case report and literature review aim to highlight the clinical features and management strategies for perioperative thyroid storm in non-thyroid surgical patients through a case analysis and literature review.Case presentationA 53-year-old Chinese male with a 20-year history of poorly controlled hyperthyroidism (irregular medication adherence) underwent closed reduction and intramedullary nailing for a right femoral fracture. …”
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Spatio-temporal changes in atmospheric aridity over the arid region of Central Asia during 1979–2019 by Moyan Li, Junqiang Yao, Jianghua Zheng

“…The first four leading modes revealed by empirical orthogonal function (EOF) analysis represented the patterns by explaining 81.4 % of the total variance. …”
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