A review on polycyclic aromatic hydrocarbons: Source, environmental impact, effect on human health and by Hussein I. Abdel-Shafy, Mona S.M. Mansour

Get full text

Development characteristics and potential of fault-fracture reservoir in southwest margin of Ordos Basin by HE Faqi, LI Junlu, GAO Yilong, WU Jinwei, BAI Xingying, GAO Dun

“…However, this also complicates the reservoir's homogeneity and the variability of its capacity, posing challenges for fine characterization of the reservoir's internal structure and for researching capacity control factors. …”
Get full text

Design of Experiment Approach for Enhancing the Dissolution Profile and Robustness of Loratadine Tablet Using D-α-Tocopheryl Polyethylene Glycol 1000 Succinate by Alhasan A. Jabbar, Israa Al-Ani, Ramadan I. Al-Shdefat, Nadia Ghazal, Anwar Jaffal, Mohamed H. Fayed

“…<b>Background:</b> Formulating poorly water-soluble drugs poses significant challenges due to their limited solubility and bioavailability. …”
Get full text

Phasic and periodic change of drought under greenhouse effect by Yang Li, Zhicheng Zheng, Yaochen Qin, Haifeng Tian, Zhixiang Xie, Peijun Rong

“…It can lead to crop reduction and even pose a threat to human survival in environmentally sensitive areas of China (ESAC). …”
Get full text

Impact of digital health management on clinical outcomes during post-PCI outpatient care in patients with acute coronary syndrome: study protocol for a multicentre, randomized cont... by Hang Yu, Wei Zhang, Wei Zhang, Guoliang Li, Tao Chen, Shaonong Dang, Xiaofeng Ma, XiaoWei Zhang, Xiaofeng Ma, Zhibin Hong, Pengyi He, Xiaohui Xu, Xiuying Chen, Yanyan Geng, Xinjun Lei, Xinjun Lei

“…Additionally, most of the previous studies have evaluated cardiac function indicators, with limited assessments of patients' clinical endpoint indicators, quality of life, and psychological aspects.Method and analysisThe purpose of this study is to explore the development of a smartphone-based systematic and extensible digital management model for post-percutaneous coronary intervention (PCI) outpatient care among ACS patients. …”
Get full text

Integrated neural network framework for multi-object detection and recognition using UAV imagery by Mohammed Alshehri, Tingting Xue, Tingting Xue, Ghulam Mujtaba, Yahya AlQahtani, Nouf Abdullah Almujally, Ahmad Jalal, Ahmad Jalal, Hui Liu, Hui Liu, Hui Liu

“…In the end, using an attention function, Vision Transformer-based models classify vehicles seen from above. …”
Get full text

Discovery of anti-Ebola virus multi-target inhibitors from traditional Chinese medicine database using molecular screening, biophysical investigation, and binding free energy calcu... by Abbas Khan, Abrar Mohammad Sayaf, Anwar Mohammad, Fahad M. Alshabrmi, Tarek Benameur, Dong-Qing Wei, Kar Kheng Yeoh, Abdelali Agouni

“…The lack of effective treatment or vaccine for this pathogen poses a serious threat to a global pandemic. Therefore, it is imperative to explore new drugs and therapies to combat this life-threatening infection. …”
Get full text

Climate and anthropogenic activities control the concentrations of copper, zinc, cadmium and chromium in global inland waters by Xia Jin, Qiqian Wu, Josep Peñuelas, Jordi Sardan, Yan Peng, Zimin Li, Xin Peng, Petr Heděnec, Qiao Yang, Chaoxiang Yuan, Ji Yuan, Zihao Chen, Zemin Zhao, Fuzhong Wu, Kai Yue

“…Abstract Pollution by heavy metals (Cu, Zn, Cd, Cr) in global inland waters poses significant threats to freshwater biodiversity and ecosystem function, yet the global patterns and drivers of heavy metals remain poorly explored. …”
Get full text

Unveiling the evolution of antimicrobial peptides in gut microbes via foundation-model-powered framework by Wenhui Li, Baicheng Huang, Menghao Guo, Zihan Zeng, Tao Cai, Linqing Feng, Xinpeng Zhang, Ling Guo, Xianyue Jiang, Yanbin Yin, Ercheng Wang, Xingxu Huang, Jinfang Zheng

“…Protein language models (PLMs) have advanced protein structure and function predictions, facilitating AMP discovery. We developed antimicrobial peptide structural evolution miner (AMP-SEMiner), an AI-driven framework that integrates PLMs, structural clustering, and evolutionary analysis to systematically identify AMPs encoded by small open reading frames and AMP-containing proteins in metagenome-assembled genomes. …”
Get full text

SFD-YOLO: A novel framework for subsidence funnels detection in China based on large-scale SAR interferograms by Jing Guo, Zhengjia Zhang, Peifeng Ma, Mengmeng Wang, Xuefei Zhang, Dongdong Li, Bing Sui

“…However, recognizing subsidence funnels of varying sizes in large-scale interferograms poses significant challenges, particularly for small-sized funnels. …”
Get full text

Voriconazole-Loaded Nanohydrogels Towards Optimized Antifungal Therapy for Cystic Fibrosis Patients by Shaul D. Cemal, María F. Ladetto, Katherine Hermida Alava, Gila Kazimirsky, Marcela Cucher, Romina J. Glisoni, María L. Cuestas, Gerardo Byk

“…Chronic colonization is linked to hypersensitivity reactions and persistent infections leading to a significant long-term decline in lung function. Azole antifungal therapy such as voriconazole (VRC) slows disease progression, particularly in patients with advanced CF; however, excessive mucus production in CF lungs poses a diffusional barrier to effective treatment. …”
Get full text

Hepatocellular carcinoma and AIM2: Therapeutic potential through regulation of autophagy and macrophage polarization by Shuangshuang Xie, Cuiyun Wang, Xiaoyan Liu, Cheng Li, Jinhong Yu, Shumin Ma, Qiang Li, Wenjun Du

“…Abstract Objective Hepatocellular carcinoma (HCC) poses a significant challenge to global health. Its pathophysiology involves interconnected processes, including cell proliferation, autophagy, and macrophage polarization. …”
Get full text

SOS3 from <i>Avicennia marina</i> Enhances Salt Stress Tolerance of <i>Arabidopsis thaliana</i> by Mariam Alzaabi, John Orpilla, Khaled Michel Hazzouri, Ling Li, Khaled Amiri

“…Abiotic stress poses a serious challenge in agriculture. Salinity inhibits crop growth and yields by disrupting ionic homeostasis and osmotic balance. …”
Get full text

Harnessing nuclear energy for India's energy security: Current status, challenges, and future opportunities by Christopher Selvam D, Yuvarajan D, Sunil Kumar M, KrishnaKumar Shukla, Chintan Patel, Bhanu Juneja, SarojKumar Acharya

“…India's escalating energy requirements, anticipated to surpass 2500 TWh by the year 2030, are primarily fulfilled through coal, which consequently leads to substantial carbon emissions and poses risks to energy security. This research endeavors to explore the function of nuclear energy as a viable, low-carbon substitute within the framework of India's energy transition. …”
Get full text

The Influence of Gold Wire Quantity on the Encapsulation of Light-Emitting Diodes by M.S. Abdul Azis, M.S. Rusdi, M.S. Zubir, Z. Embong, M. Nabiałek

“…Leveraging ANSYS Fluent, our study employs the Volume of Fluid (VOF) technique along with a user-defined function (UDF) to model the deposition of epoxy materials onto the LED. …”
Get full text

Physiological and biochemical indicators in blood of captive yellow-cheeked gibbons and northern white-cheeked gibbons by Wanrong Song, Yujuan Hu, Minghao Cheng, Tianchun Pu, Wenhui Niu, Yizhuo Zhang, Xuefeng Liu, Yunsheng Wang, Yuguang Zhang, Jinpeng Liu, Yipeng Jin

“…However, the lack of established physiological and biochemical reference ranges currently poses substantial challenges to effective clinical assessment and disease identification in these primates. …”
Get full text

Transformation of the legal regulation of tax relations in the digital economy context by E. Yu. Gracheva, N. M. Artemov, K. A. Ponomareva

“…The research was carried out with the application of the formally legal interpretation of legal acts as well as the comparative analysis of Russian and European legal literature. …”
Get full text

On the Question of the Semantic Understanding of the Cartoon by Preschoolers by Vladimir S. Sobkin, Irina A. Ryabkova, Nadezhda E. Antufueva, Mariya S. Sokolova

“…In this regard, the need for a deeper study of this issue and the analysis of the semantic perception of cartoons at preschool age becomes particularly relevant. …”
Get full text

Modeling of Battery Storage of Photovoltaic Power Plants Using Machine Learning Methods by Rad Stanev, Tanyo Tanev, Venizelos Efthymiou, Chrysanthos Charalambous

“…Also, as part of the deep learning FNN analysis study, a customized early stopping function is introduced. …”
Get full text

Exploration of effective pharmacological inhibitors for NS5 protein through computational approach: A strategy to combat the neglected Kyasanur forest disease virus. by Sharanappa Achappa, Nayef Abdulaziz Aldabaan, Mohammed Alasmary, Ibrahim Ahmed Shaikh, Mater H Mahnashi, Shivalingsarj V Desai, Uday M Muddapur, Aejaz Abdullatif Khan, Basheerahmed Abdulaziz Mannasaheb

“…Kyasanur Forest Disease Virus (KFDV) poses a significant public health threat due to the limited efficacy of existing vaccines, necessitating the development of effective antiviral therapeutics. …”
Get full text