Contextual Regularization-Based Energy Optimization for Segmenting Breast Tumor in DCE-MRI by Priyadharshini Babu, Mythili Asaithambi, Sudhakar Mogappair Suriyakumar

“…An iterative gradient descent algorithm is engaged to minimize the energy-based cost function, obtaining stable convergence towards the optimal solution. …”
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FMEA Risk Assessment Method for Aircraft Power Supply System Based on Probabilistic Language-TOPSIS by Zicheng Xiao, Zhibo Shi, Jie Bai

“…These include the risk of inaccurate risk level judgment and the potential for misjudgments due to human factors, both of which pose significant threats to the safe operation of aircraft. …”
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Prevalence and determinants of restrictive lung disorder among quarry workers at the Umuoghara quarry site, Ebonyi State, Nigeria: a cross-sectional study by Ngozika Substance Ike-Samuel, Osaeloka C. Ekwueme, Susan Chioma Udeh

“…Abstract Introduction Respiratory disorders pose a serious health risk for quarry workers exposed to dust, as they are a leading source of morbidity and mortality globally, often resulting in irreversible lung conditions. …”
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Age-dependent mechanisms of exercise in the treatment of depression: a comprehensive review of physiological and psychological pathways by Peng Xue, Xingbin Du, Xingbin Du, Jianda Kong

“…The rising incidence rate and disability rate pose a serious challenge to public health and socio-economic development. …”
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ConvNeXt embedded U-Net for semantic segmentation in urban scenes of multi-scale targets by Yanyan Wu, Qian Li

“…Abstract Semantic segmentation of urban scenes is essential in urban traffic analysis and road condition information acquisition. …”
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Revisiting polychlorinated biphenyls enriching in human and disrupting of thyroid hormone receptor β1 by Qiao Wang, Junsong Bao, Yuhao Fan, Junjie Jiang, Ying Wang, Limei Chen, Jun Jin

“…Although PCBs production and use were banned worldwide decades ago, PCBs still pose a health risk due to their environmental persistence and unintentional production. …”
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Synergistic effect and mechanism of meropenem with ciprofloxacin against carbapenem-resistant Acinetobacter baumannii by Ying Feng, Xu Chen, Yu Sun, Tingting Guo, Feng Wu, Feng Jin, Jun Zhou

“…Checkerboard and Growth Curve assays demonstrated that the combination of ciprofloxacin and meropenem had significant bactericidal effects on CRAB, outer membrane permeability, membrane potential, and reactive oxygen species generation. Transcriptomic analysis revealed that the combination inhibited efflux pump function, reduced iron uptake, and impacted metabolic pathways, membrane protein synthesis, and stress responses, thereby enhancing bacterial killing.DiscussionThe findings from this study underscore the synergistic effect of ciprofloxacin and meropenem not only offers a potential alternative treatment strategy but also highlights the importance of combination therapy in overcoming antibiotic resistance, which pose a significant threat to public health.…”
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The PHD transcription factor Cti6 is involved in the fungal colonization and aflatoxin B1 biological synthesis of Aspergillus flavus by Zhang Mengjuan, Lin Guanglan, Pan Xiaohua, Song Weitao, Tan Can, Chen Xuan, Yang Yanling, Zhuang Zhenhong

“…Bioinformatics analysis showed Cti6 is conservative in Aspergillus spp., and mCherry mediated subcellular localization showed that most Cti6 accumulated in the nuclei, which reflected that Cti6 performed its important biological function in the nuclei in Aspergillus spp.. …”
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Application of deep learning for diagnosis of shoulder diseases in older adults: a narrative review by Sung Min Rhee

“…Shoulder diseases pose a significant health challenge for older adults, often causing pain, functional decline, and decreased independence. …”
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Case Report: Custom made 3D implants for glenoid tumor reconstruction should be designed as reverse total shoulder arthroplasty by Robin Evrard, Robin Evrard, Antoine Ledoux, Pierre-Louis Docquier, Pierre-Louis Docquier, Florine Geenens, Thomas Schubert, Thomas Schubert

“…Patients files were reviewed for radiographic analysis, pain and function scores.ResultsMean follow-up was 36.44 ± 16.27 months. …”
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PhotoNeuro: A compact photodetector for synchronization of visual stimulus presentation during behavioural experiments in neuroscience by Xavier Cano-Ferrer, Marcelo J. Moglie, George Konstantinou, Antonin Blot, Gaia Bianchini, Albane Imbert, Petr Znamenskiy, M. Florencia Iacaruso

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Safety–Efficiency Balanced Navigation for Unmanned Tracked Vehicles in Uneven Terrain Using Prior-Based Ensemble Deep Reinforcement Learning by Yiming Xu, Songhai Zhu, Dianhao Zhang, Yinda Fang, Mien Van

“…First, by integrating kinematic analysis, we introduce a novel state and an action space that account for rugged terrain features and track–ground interactions. …”
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Recurrent Infections in Allergic Pediatric Patients: An Immune System Problem? A Narrative Review by César Galván, Rafael Durán, Cristian Matos, Cristiana Indolfi, Angela Klain

“…<b>Background/Objectives:</b> Recurring infections in children with allergies pose significant clinical challenges, with these conditions often exacerbating each other through complex immunological interactions. …”
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Kernel-based response extraction approach for efficient configurable ring oscillator PUF by Enas Abulibdeh, Hani Saleh, Baker Mohammad, Mahmoud Al-Qutayri, Asif Hussain

“…Abstract The Physically Unclonable Function (PUF) is an emerging hardware security primitive that provides a promising solution for lightweight security. …”
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GazeMap: Dual-Pathway CNN Approach for Diagnosing Alzheimer’s Disease from Gaze and Head Movements by Hyuntaek Jung, Shinwoo Ham, Hyunyoung Kil, Jung Eun Shin, Eun Yi Kim

“…Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that impairs cognitive function, making early detection crucial for timely intervention. …”
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Single-cell sequencing reveals dysregulated cell type perturbations and critical mediator communication remodelling in colorectal cancer by Chengyuan Xu, Chengyuan Xu, Siqi Zhang, Zhouyu Zhang, Luoqiu Zhang, Bin Sun, Zicheng Yu, Hailong Liu

“…BackgroundThe heterogeneity of colorectal cancer (CRC) and its complex immune microenvironment pose significant challenges for treatment. Understanding the cellular composition and dynamic changes is essential for uncovering mechanisms of tumour progression.MethodsTo investigate the cellular heterogeneity and immune microenvironment of CRC, identifying critical subpopulations, functional pathways, and prognostic biomarkers, single-cell transcriptomic data from 41 CRC samples across four datasets were integrated. …”
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Precision medicine in premature ovarian insufficiency: a focus on the precision therapeutic strategies for mesenchymal stem cells by Rou Wang, Fengyuan Liu, Qiuyue Liao, Jiachen Wu, Lingjuan Wang, Kezhen Li

“…And mesenchymal stem cells (MSCs) have gradually been regarded as a promising therapeutic approach for POI for their potential in remodeling impaired ovarian function. However, specific details regarding the application of MSCs in POI treatment remain unclear. …”
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Reconstruction of reservoir rock using attention-based convolutional recurrent neural network by Indrajeet Kumar, Anugrah Singh

“…The reservoir rocks (such as sandstone and carbonate) contain both spatial and temporal characteristics, which pose a big challenge in their characterization through routine core analysis or x-ray microcomputer tomography. …”
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A Convolutional Neural Network for Early Supraventricular Arrhythmia Identification by Emilio J. Ochoa, Luis C. Revilla

“…Supraventricular arrhythmias (SVAs), including the often-asymptomatic supraventricular extrasystole (SVE), pose significant challenges in early detection and precise diagnosis. …”
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O systemach sztucznej inteligencji w kontekście praw człowieka w orzecznictwie Europejskiego Trybunału Praw Człowieka by Martyna Kaczmarczyk

“…The research problems addressed by this analysis indicate ECHR judgments related to new technologies and to assessing their significance for the functioning of artificial intelligence and discussing its relevance for the future. …”
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