12,13-diHOME protects against the age-related decline in cardiovascular function via attenuation of CaMKII by Shinsuke Nirengi, Benjamin Buck, Devleena Das, Carmem Peres Valgas da Silva, Jazmin Calyeca, Lisa A. Baer, Hsiang-Ling Huang, Pablo Vidal, Revati S. Dewal, Kelsey M. Pinckard, Elisa Félix-Soriano, Diego Hernandez-Saavedra, Andrew Gerea, Kavya Dathathreya, Silvia Duarte-Sanmiguel, Ty A. Saldana, Harrison L. Hookfin, Matthew W. Gorr, Valerie Bussberg, Juan J. Aristizabal-Henao, Michael A. Kiebish, Roeland J. W. Middelbeek, Laurie J. Goodyear, Paul M. Coen, Krishna Chinthalapudi, Loren E. Wold, Ana L. Mora, Thomas J. Hund, Daniel Gallego-Perez, Kristin I. Stanford

“…This study investigates the potential of the brown adipose tissue (BAT) derived lipokine 12,13-diHOME to mitigate age-induced impairments in cardiovascular function. Analysis of human and rodent plasma signaling lipids reveals a decline in 12,13-diHOME levels with age. …”
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Lysozyme functionalized zinc-oxide nanoparticles: Synthesis, characterization, and antibacterial assessment against Staphylococcus aureus with futuristic application in wastewater... by Suneeti Singh, Pavni Rekhi, Jewel Mary Saju

“…Similarly, ZnO@LY NPs exhibited a 25 % stronger and statistically significant antibacterial impact than non-functionalized ZnO NPs in the bacterial growth inhibition assay, as confirmed by repeated measures (RM)-ANOVA analysis. …”
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A highly fluorinated functionalized magnetic covalent organic framework for high-efficient extraction of aflatoxins from diverse food matrices by Dan Wei, Jianliang Li, Yixuan Ni, Qiao Deng, Ming Guo, Zuxin Wang, Huizhen Wu, Xu Wang, Jingjing Xu

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Nonlinear Equation Solver with MATLAB Graphical User Interface by Nur Idalisa Norddin, Nurul Hafawati Fadhilah, Muhammad Azri Azman Shah, Nurul Hajar Mohd Yusoff, Nur Intan Syafinaz Ahmad

“… Nonlinear systems of equations, which is common in scientific and engineering fields, pose a significant difficulty because they may have numerous solutions and are complicated to be numerically solved. …”
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Prevalence of Chronic Obstructive Pulmonary Disease and Asthma in the Community of Pathumthani, Thailand by Narongkorn Saiphoklang, Pitchayapa Ruchiwit, Apichart Kanitsap, Pichaya Tantiyavarong, Pasitpon Vatcharavongvan, Srimuang Palungrit, Kanyada Leelasittikul, Apiwat Pugongchai, Orapan Poachanukoon

“…<b>Background</b>: Airway diseases, particularly asthma and chronic obstructive pulmonary disease (COPD), pose significant respiratory problems. The prevalence and risk factors of these diseases among community dwellers vary geographically and because of underdiagnosis. …”
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Screening of Aflatoxin B1-Degrading Strains and Functional Mining of Key Enzyme Genes in Pseudomonas promysalinigenes CT1-8 by Zhaofu CHEN, Zhilin WANG, Jing LIU, Shijuan YAN, Junjin DENG

“…【Objective】Aflatoxin B1 (AFB1), one of the most toxic natural carcinogens known, poses severe threats to human health and food safety. …”
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Relationship Between Internet Use and Cognitive Function Among Middle-Aged and Older Chinese Adults: 5-Year Longitudinal Study by Bowen Chen, Chun Yang, Shanshan Ren, Penggao Li, Jin Zhao

“…Moreover, we assessed the mediating role of internet use on cognitive function for characteristics significantly linked to cognition in stratified analysis. …”
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Innovative polypropylene-based adsorbent functionalized by oxygen plasma and L-Arginine for efficient removal of emerging contaminants from aqueous media by Mojtaba Azizi, Mahdi Akhgari, Maryam Esmkhani, Hossein Ghafuri, Shahrzad Javanshir

“…The existence of organic pollutants such as dyes and antibiotics in water poses serious health risks. The use of oxygen plasma to functionalize and apply oxygen containing functional groups onto surfaces can convert them to precious and useful adsorbents. …”
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Functional traits as indicators of maize (Zea mays L.) strategies to cope with Zn, Pb and Cr heavy metal-induced stress by Lina Fusaro, Francesca Lanni, Laura Varone, Giuseppina Falasca, Silvia Serranti, Riccardo Gasbarrone, Davide Gattabria, Vincenza Cozzolino, Alessandro Piccolo, Fausto Manes

“…Abstract Heavy metals (HMs) contamination poses a significant threat to environmental matrices, particularly soil, which is essential for food security, agricultural productivity, and key ecosystem services. …”
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Correlation between religiosity, family functioning, and factors associated with substance use among secondary school students in high-risk areas. by Noor Adnin Ab Aziz, Suzaily Wahab, Rosnah Sutan, Muhammad Adib Baharom, Amirul Danial Azmi, Siti Azirah Asmai

“…<h4>Introduction</h4>Substance use in adolescents poses a complex societal challenge, undermining nation-building and socioeconomic growth. …”
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A Kind of Robot Structure Design and Kinematics Analysis by Yankai Hu, Hui Fu

“…Humanoid robots are an important part of the field of robotics，and their characteristics analysis involves disciplines such as machinery，electronics，and materials. …”
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Flash flood disaster risk evaluation based on geographic detector and interval number ranking method by Xiao Liu, Ronghua Liu, Xiaolei Zhang, Qi Liu

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The impact of low dietary inflammatory index diet on clinical parameters in patients with chronic kidney disease: a retrospective comparative study by Weijuan Pan, Jian Feng

“…Abstract Background Chronic kidney disease (CKD) poses a significant global health challenge. Inflammation plays a central role in the pathogenesis and progression of CKD, which has been proved to be affected by dietary patterns. …”
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New threats in the cyberspace based on the analysis of The Onion Router by Anna Nastuła

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Targeting CD16A on NK cells and GPC3 in hepatocellular carcinoma: development and functional validation of a therapeutic bispecific antibody by Liu Chen, Yuankui Zhu, Mingqian Feng, Mingqian Feng, Dianbao Zuo, Guoping Chen, Kangkang Ji, Kangkang Ji

“…To address this unmet need, we developed a bispecific antibody (BsAb) platform targeting CD16A on natural killer (NK) cells and glypican-3 (GPC3), a tumor-specific antigen overexpressed in 70% of HCC cases.MethodsHigh-affinity anti-CD16A single-chain variable fragments (scFvs) were selected via phage display, followed by engineering of Fc-stabilized BsAbs (MA4-hFc(N297A)-CD16A series) to minimize FcγR-mediated toxicity. Functional validation included binding kinetics (ELISA, flow cytometry, and fluorescence co-localization analysis), in vitro cytotoxicity assays (luciferase-based killing), and in vivo efficacy studies in Huh7 xenograft models. …”
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Integrated assessment of left atrial function and C-reactive protein levels for severity of coronary artery ectasia: observational case–control study by Eman Samy EL Shehawy, Badria Atef Ebrahim Elhalawany, Bassem Abdelhady

“…We sought to investigate left atrial mechanical functions through 2D strain analysis in individuals with isolated CAE and compare them to controls with normal coronary angiography, examining its correlations with C-reactive protein (CRP) levels and CAE severity. …”
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Density Functional Theory Insight in Photocatalytic Degradation of Dichlorvos Using Covalent Triazine Frameworks Modified by Various Oxygen-Containing Acid Groups by Shouxi Yu, Zhongliao Wang

“…First, simulations of the structure and optical properties of modified CTFs reveal that oxygen-containing acid groups induce surface distortion and result in a redshift in the absorption edge. Subsequently, analysis of the density of states, frontier molecular orbitals, surface electrostatic potential, work function, and dipole moment demonstrates that oxygen-containing acid groups enhance CTF polarization, facilitate charge separation, and ameliorate their oxidative capability. …”
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Like-layers resolution deficiency in structure function-based thermal test for multilayer semiconductor device and its potential cure by interface design by Xintian Gao, Junjie Wu, Yulin Chen, Haotian Huang, Yuan Zhu

“…Structure function method (SFM) as an important commercialized measurement method for layered analysis of thermal resistance and thermal capacity, has been widely used and keeps attracting broad research interests from industry. …”
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Bibliometric and visualized analysis of the applications of exosomes for bone regeneration by Shuai Ai, Zhou Xie, Ningdao Li, Runhan Zhao, Xiao Qu, Haining Zhou, Dagang Tang, Jun Zhang, Xiaoji Luo, Xiaoji Luo

“…Additionally, most research hotspots focused on the function of exosomes and the mechanism of action. Furthermore, the importance of osteoblast differentiation and angiogenesis in bone regeneration has also garnered significant attention from scholars in this field.ConclusionThis study reviewed the research achievements on the application of exosomes for bone regeneration over the past 10 years, utilizing bibliometric analysis tools. …”
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New insights into the combined effects of aflatoxin B1 and Eimeria ovinoidalis on uterine function by disrupting the gut–blood–reproductive axis in sheep by Shu-cheng Huang, Kai-li Liu, Pan Chen, Bo-wen Xu, Wen-li Ding, Tao-jing Yue, Ya-nan Lu, Sen-yang Li, Jia-kui Li, Fu-chun Jian

“…Cereal grains and animal feeds are frequently contaminated with mycotoxins worldwide, with aflatoxin B1 (AFB1) being the most common form. AFB1 poses a serious threat to gastrointestinal health upon ingestion and affects the function of parenteral organs, thus endangering livestock health. …”
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