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Strategies for the Viral Exploitation of Nuclear Pore Transport Pathways
Published 2025-01-01“…Viruses frequently exploit the host’s nucleocytoplasmic trafficking machinery to facilitate their replication and evade immune defenses. …”
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Shale-pore Semantic Segmentation Network Based on Pseudo-labeling
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A Unified Model for the Soil Freezing Characteristic Curve Based on Pore Size Distribution and Principles of Thermodynamics
Published 2025-03-01“…The model eliminates the need for iterative calculations by deriving a freezing point depression equation that links the effects of confinement and solute concentration to pore size. …”
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Gasdermin-D pores induce an inactivating caspase-4 cleavage that limits IL-18 production in the intestinal epithelium
Published 2025-05-01“…In human intestinal epithelial cell lines and in primary human epithelial intestinal organoids, but not in immune cells, GSDMD plasma membrane pore formation by LPS electroporation and by gram-negative bacterial infection induced a non-conventional p37 caspase-4 fragment that was associated with reduced levels of mature IL-18. …”
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Controlling pore size during the synthesis of hydroxyapatite nanoparticles using CTAB by the sol–gel hydrothermal method and their biological activities
Published 2024-12-01“…These findings indicate that the pore size and shape of HAP play significant roles in their biological activities.…”
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SLO co-opts host cell glycosphingolipids to access cholesterol-rich lipid rafts for enhanced pore formation and cytotoxicity
Published 2025-03-01“…SLO is a member of a family of bacterial pore-forming toxins known as cholesterol-dependent cytolysins, which require cell membrane cholesterol for pore formation. …”
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Evaluating water injection compatibility and scale-formation reduction in a middle east reservoir using direct pore-scale visualization and NaOH treatment
Published 2025-04-01“…When water combines with the formation water, it can form sediments that cause incompatibility, leading to the precipitation of inorganic scale deposits in surface facilities, flow lines, wells, and even the reservoir itself. Therefore, it is crucial to design the injected water to minimize incompatibility. …”
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Macro–Micro Correlation Mechanism Between Structural Potential and Mechanical Strength in Collapsible Loess
Published 2025-06-01“…This framework quantitatively links grain size, pore potential, and connection potential to the collapsibility of loess. …”
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Freshwater Seepage Into Sediments of the Shelf, Shelf Edge, and Continental Slope of the Canadian Beaufort Sea
Published 2018-09-01“…Extrapolations to zero Cl− of pore water Cl− versus δ180 regression lines indicate that freshwaters in these environments carry different isotope signatures and thus are sourced from different reservoirs. …”
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A bacterial membrane-disrupting protein stimulates animal metamorphosis
Published 2025-02-01“…MACs can also deliver Mif1 to human cell lines and cause parallel phenotypes, including cell surface binding, membrane disruption, calcium flux, and mitogen-activated protein kinase activation. …”
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Inclusion Modeling of Bucket Elevator Conveyor Chain Links
Published 2020-01-01“…Inclusions, pores, and cracks which are defects in materials are important in determining the structural integrity and durability of components. …”
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Classification evaluation and distribution characteristics of sandstone interlayer reservoirs: A case study of the first member of Qingshankou Formation in Daqingzijing area, Chang...
Published 2024-10-01“…From Class Ⅰ to invalid reservoirs, there is a sequential decrease in the content of large and medium pores, with reservoir space transitioning from intergranular pores and intergranular solution pores to intragranular solution pores and intergranular pores. …”
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Asporin increases the extracellular matrix cross-links and inhibits the cancer cell migration
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RESIDUAL OPERATIONAL RESOURCE ASSESSMENT OF HIGH TEMPERATURE ELEMENTS OF POWER ENGINEERING EQUIPMENT
Published 2014-04-01Get full text
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Gasdermin E links tumor cell-intrinsic nucleic acid signaling to proinflammatory cell death for successful checkpoint inhibitor cancer immunotherapy
Published 2025-12-01“…We here show that intratumoral activity of the pore-forming protein gasdermin E (GSDME) links active RIG-I signaling and apoptotic cell death in tumor cells to inflammatory pyroptosis. …”
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