Influence of large-scale atmospheric circulation and Mediterranean sea surface temperature to extreme land precipitation: the case of storm Alex by Laurent Terray, Margot Bador

“…We first show that the mean effect of the observed atmospheric circulation pattern, an intense low-pressure system centered over the coasts of Western Europe associated with a cold pool and a secondary low-pressure system, can explain about 80% of the precipitation event magnitude. …”
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Investigating hydraulic anisotropy of fractured rock mass using three-dimensional numerical modelling and laser scanning: a case study at South Crofty mine in Cornwall, UK by Lingfeng He, Matthew Eyre, John Coggan, Steve Holley, Dave Watkins

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Establishing expert consensus on Chinese herbal medicine for rheumatoid arthritis management in Singapore by Ang Loh, Huijuan Li, Wai Ching Lam, Yan Yin Tjioe, Warren Fong, Linda L.D. Zhong

“…However, the findings are limited by the demographic composition of the experts and the representativeness of the patient pool.…”
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Experimental study on fire behavior in blind roadway fires at initial sealing time by FU Yuexuan, WU Bing, WANG Jingxin, CHANG Cheng, WEN Xinyi, MA Xinhang, WANG Guangyuan

“…The distinct structural characteristics of a blind roadway lead to differences in the fire behavior and smoke transport characteristics of oil pool fires in blind roadway and in other scenarios since one end of a blind roadway is a completely sealed heading face while the other end is connected to the main roadway.This study conducted small-scale experiments to investigate the smoke transport characteristics at different initial sealing times in blind roadways.Results show that delayed initial sealing time could cause increasing accumulation of smoke and higher temperature in the blind roadway.However, such pattern was not valid at a distance of 0 m from the fire source since temperature was affected by the flame inclination angle.After sealing, the oxygen volume fraction significantly decreased.As it dropped to a certain value, the fire source would self-extinguish or be in a state of imminent self-extinguishment.Combustion demanded less oxygen, and fresh air in the main roadway would enter the blind roadway through gaps, with the oxygen volume fraction showing an upward trend.Carbon monoxide concentration was generally higher in working conditions with an earlier initial sealing time than that with a delayed initial sealing time as fuel combustion became insufficient within a short time span.This is not explicit in working conditions with a larger oil pan size.…”
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Substantial shift in phase and amplitude of Indian rainfall beyond 2100 by Sahil Sharma, Kyung-Ja Ha, Keith B. Rodgers, Eui-Seok Chung, Sun-Seon Lee, Arjun Babu Nellikkattil

“…Meanwhile, the westward expansion is linked to uneven warming in the Indian Ocean as the warm pool shifts westwards. These circulation changes, combined with the asymmetric warming pattern, enhance northward moisture transport and contribute to the intensification of rainfall across northwestern and northern India post-2100. …”
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Public health implications of multidrug-resistant and methicillin-resistant Staphylococcus aureus in retail oysters by Rahma Mohammed, Sara M. Nader, Dalia A. Hamza, Maha A. Sabry

“…Interestingly, two MDR-MRSA isolates exhibited a clustered pattern. The study sheds light on the emergence of virulent MDR-MRSA isolates in Egyptian oysters. …”
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Inaccurate DNA synthesis in cell extracts of yeast producing active human DNA polymerase iota. by Alena V Makarova, Corinn Grabow, Leonid V Gening, Vyacheslav Z Tarantul, Tahir H Tahirov, Tadayoshi Bessho, Youri I Pavlov

“…The primer/template and composition of the exogenous DNA precursor pool can be adapted to monitor replication fidelity in cell extracts expressing various error-prone Pols or mutator variants of accurate Pols. …”
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Physical activity and screen time among children and adolescents in Kazakhstan by Kwok Ng, Shynar Abdrakhmanova, Assel Adayeva

“…  Despite some limitations in the methodologies between the COSI and HBSC surveys, and reporting of behaviours, there is a clear pattern that health promoting activities lowers as children transition into young adolescents.…”
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The formation of endoderm-derived taste sensory organs requires a Pax9-dependent expansion of embryonic taste bud progenitor cells. by Ralf Kist, Michelle Watson, Moira Crosier, Max Robinson, Jennifer Fuchs, Julia Reichelt, Heiko Peters

“…Unexpectedly, Pax9 is dispensable for patterning, morphogenesis and maintenance of taste buds that develop in ectoderm-derived fungiform papillae. …”
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Adolescence in flux: Unmasking 30 years of change in subnational parity-specific adolescent fertility in Mexico by Ann Garbett, Sara Neal, Angela Luna Hernandez, Nikos Tzavidis

“…The results unmask 30 years of flux and a surprising pattern of convergence in first births alongside little concordance for second births. …”
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Nuclear and Chloroplast Markers Provide New Insights Into the Syngameon Dynamics of Genus Micromeria (Lamiaceae) in the Canary Islands by Manuel Curto, Pamela Puppo, Harald Meimberg

“…Syngameons facilitate sharing the gene pool among species while maintaining morphological differentiation. …”
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DNMT3A regulates murine megakaryocyte-biased hematopoietic stem cell fate decisions by Sarah M. Waldvogel, Virginia Camacho, Dandan Fan, Anna G. Guzman, Alejandra Garcia-Martell, Elmira Khabusheva, Jacey Rodriguez Pridgen, Josephine De La Fuente, Rachel Rau, Ashlyn G. Laidman, Maria N. Barrachina, Estelle Carminita, Justin A. Courson, Michael R. Williamson, Joanne I. Hsu, Chun-Wei Chen, Jaime Reyes, Subhashree Pradhan, Rolando E. Rumbaut, Alan R. Burns, Benjamin Deneen, Jianzhong Su, Kellie R. Machlus, Margaret A. Goodell

“…Although transcriptional differences between WT and Dnmt3a+/– megakaryocyte-biased HSCs are subtle, the pattern of DNA methylation loss in this HSC subset is almost completely different from that in non–megakaryocyte-biased HSCs. …”
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Does the timing of parental divorce or separation impact adolescent and young adult mental health differently by gender? by Sam Hugh-Jones, Rose Atkins, Stephanie Gillibrand, Anna Wilding, Luke Munford, Matt Sutton

“…When using alcohol consumption as an alternative outcome, we found the same pattern of results for females, and also found that early parental divorce (before age 15) was associated with increased alcohol consumption at age 15 in males, but reduced consumption at age 25. …”
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Stress granules formation in HEI-OC1 auditory cells and in H4 human neuroglioma cells secondary to cisplatin exposure by Hebatallah Abdelrasol, Avika Chopra, Liana Shvachiy, Dirk Beutner, Tiago F Outeiro, Cristian Setz

“…Stress granules (SGs) are highly dynamic micromolecular membraneless condensates that generate in cells subjected to stress. Formed from pools of untranslating messenger ribonucleoproteins (RNP), SGs dynamics constitute vital processes essential for cell survival. …”
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Epstein Barr virus antibody and cancer risk in two prospective cohorts in Southern China by Ming-Fang Ji, Yong-Qiao He, Min-Zhong Tang, Wen-Qiong Xue, Xia Yu, Hua Diao, Da-Wei Yang, Zhi-Ming Mai, Io Hong Cheong, Zhi-Yang Zhao, Biao-Hua Wu, Fu-Gui Li, Ji-Yun Zhan, Chang-Ling Huang, Hao-Lin Ma, Jun Li, Yan-Cheng Li, Tong-Min Wang, Ying Liao, Xue-Yin Chen, Zhi-Heng Liang, Shi-Feng Lian, Yun Du, Xue-Jun Liang, Zisis Kozlakidis, Jun Ma, Wei-Hua Jia

“…The associations showed an increased dose-response pattern, and keep persistent even up to ten years prior to diagnosis. …”
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Heritability and Genetics of Type 2 Diabetes Mellitus in Sub-Saharan Africa: A Systematic Review and Meta-Analysis by Evans Adu Asamoah, Christian Obirikorang, Emmanuel Acheampong, Max Efui Annani-Akollor, Edwin Ferguson Laing, Eddie-Williams Owiredu, Enoch Odame Anto

“…Data extracted included the study design, records of family history, pattern and characteristics of inheritance, genetic determinants, and effects estimates. …”
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Digital Rectal Examination Is a Valuable Bedside Tool for Detecting Dyssynergic Defecation: A Diagnostic Study and a Meta-Analysis by Jie Liu, Chaolan Lv, Yizhou Huang, Ying Wang, Dandan Wu, Cong Zhang, Chenyu Sun, Wei Wang, Yue Yu

“…A total of 101 patients (46.33%) had a DD pattern using HRAM, while 117 patients (53.67%) were diagnosed without DD. …”
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Changes in the Adult GluN2B Associated Proteome following Adolescent Intermittent Ethanol Exposure. by H Scott Swartzwelder, Mary-Louise Risher, Kelsey M Miller, Roger J Colbran, Danny G Winder, Tiffany A Wills

“…Tissue extracts were fractionated into synaptic and non-synaptic pools, immuno-precipitated for GluN2B, and then analyzed using proteomic methods. …”
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In Vivo Validation of a Metacarpophalangeal Joint Orthotic Using Wearable Inertial Sensors in Horses by Eleonora Pagliara, Federica Cantatore, Livio Penazzi, Barbara Riccio, Andrea Bertuglia

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Immune checkpoint inhibitors as first line in advanced melanoma: Evaluating progression‐free survival based on reconstructed individual patient data by Andrea Ossato, Vera Damuzzo, Paolo Baldo, Daniele Mengato, Marco Chiumente, Andrea Messori

“…Information on PFS from these trials was pooled according to the following treatments: nivolumab or pembrolizumab as monotherapy, or in combination with ipilimumab, and relatlimab + nivolumab. …”
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