Improving antibiotic utilization in West Africa: enhancing interventions through systematic review and evidence synthesis by Eric S. Donkor, Abdul-Halim Osman, Bill Clinton Aglomasa, Aaron Awere-Duodu, Alex Odoom, Bismark Opoku-Asare, Gilbert Lazarus

“…Antibiotic consumption for inpatients has a pooled estimate of 620.03 defined daily dose (DDD) per 100 bed-days (confidence interval [CI] 0.00–1286.67; I2 = 100%) after accounting for outliers while prescribing appropriateness ranged from 2.5% to 93.0% with a pooled estimate of 50.09 ([CI: 22.21–77.92%], I2 = 99.4%). …”
Get full text

Changes in Microbial Necromass Carbon in Soil Profiles of Grasslands with Different Stages of Restoration in a Karst Region by Xuefeng Wu, Heng Liu, Xiaolong Bai, Dongpeng Lv, Mingzhi Lv, Yurong Yang, Wangjun Li

“…However, its distribution patterns across soil profiles and grassland restoration stages in karst areas remain unclear. …”
Get full text

VERBAL, SOCIAL AND BIOGENETIC CODES OF EMOTION EXTERNALIZATION: AN AFFECTIVE-DISCURSIVE ACCOUNT by Iryna P. Pinich

“…Current emotion theories in linguistics, philosophy, and psychology exhibit a general tendency towards the integration of embodied emotional and sensual experience in epistemic and sense-making practices of social interaction. An emotional pool proves indispensable from the pool of knowledge and involves shared experience of affective and emotional responses, their conventionalized and sedimented externalization, the library of verbal and nonverbal means of their manifestation, regulation, negotiation, and channeling. …”
Get full text

Spatiotemporal Trends in the Prevalence of Obstructive Sleep Apnoea Across China: A Multilevel Meta-Analysis Incorporating Geographic and Demographic Stratification (2000-2024) by Niu Y, Sun S, Wang Y, Chen L, Shao Y, Zhang X

“…Random-effects models pooled prevalence estimates; meta-regression identified heterogeneity contributors. …”
Get full text

Emergence of a Novel Dengue Virus Serotype-2 Genotype IV Lineage III Strain and Displacement of Dengue Virus Serotype-1 in Central India (2019–2023) by Ashish Kumar Yadav, Rashmi Chowdhary, Arshi Siddiqui, Anvita Gupta Malhotra, Jagat R. Kanwar, Ashok Kumar, Debasis Biswas, Sagar Khadanga, Rajnish Joshi, Abhijit Pakhare, Sudhir Kumar Goel

“…This study investigated the dynamics of dengue virus transmission and evolution in Central India from 2019 to 2023, focusing on the emergence of new strains and their impact on outbreak patterns. For this, 40 mosquito pools and 300 patient samples were recruited for the study. …”
Get full text

Prevalence of Bacterial Pathogens Isolated from Canines with Pyoderma and Otitis Externa in Korea: A Systematic Review and Meta-Analysis by Maryum Tanveer, Eurade Ntakiyisumba, Fabrice Hirwa, Hakyoung Yoon, Sang-Ik Oh, Chongchan Kim, Mi Hye Kim, Ji-Seon Yoon, Gayeon Won

“…Of the 944 articles, 29 met the eligibility criteria. The pooled bacterial prevalence among infected dogs was 99.95% (95%CI: 99.85–100). …”
Get full text

Biodiversity and Abundance of Angiosperms and Environmental Resilience in the Tidal Range of Yuanjiang Dry–Hot Valley, Southwestern China by Fengchun Yang, Qiong He, Huaping Huang, Yanmei Cui, Jianyong Gou, Chaya Sarathchandra, Kritana Prueksakorn, Kiyota Hashimoto, Li Liu

“…This study explored the relationship between diversity patterns of plant species and their environments in the lowland of this dry–hot valley. …”
Get full text

Classification of Wetlands in the Liaohe Estuary Based on MRMR-RF-CV Feature Preference of Multisource Remote Sensing Images by Lina Ke, Shilin Zhang, Yao Lu, Nan Lei, Changkun Yin, Qin Tan, Lei Wang, Daqi Liu, Quanming Wang

“…Understanding the distribution and evolutionary patterns of complex wetland types is essential for advancing wetland conservation, exploring blue carbon potentials, and supporting national carbon neutrality goals. …”
Get full text

Phylogenomic relationships and species delimitation of Cotoneaster ser. Pannosi, ser. Buxifolii, and related taxa by Jiaxuan Huang, Sufang Chen, Kaikai Meng, Mingwan Li, Wanyi Zhao, Na Wang, Qiang Fan, Wenbo Liao

“…Fourteen species satisfied all criteria, corresponding to nine distinct gene pools, while the remaining 13 species displayed admixed genomic compositions and cytonuclear discordances, indicative of hybrid origins. …”
Get full text

Heat Waves and Early Birth: Exploring Vulnerability by Individual‐ and Area‐Level Factors by A. Fitch, M. Huang, M. J. Strickland, A. J. Newman, C. Kalb, J. L. Warren, S. Kelley, X. Zheng, H. H. Chang, L. A. Darrow

“…Heat‐related early term birth risk is enhanced among subgroups associated with socioeconomic disadvantage, but patterns of vulnerability were less consistent for preterm birth.…”
Get full text

Machine Learning-Based Intrusion Detection Systems for the Internet of Drones: A Systematic Literature Review by Mostafa Ogab, Sofiane Zaidi, Abdelhabib Bourouis, Carlos T. Calafate

“…Existing Intrusion Detection Systems (IDS) for IoD face several limitations, including high false positive rates, resource constraints of drones, limited adaptability to evolving attack patterns, and a lack of standardized datasets for benchmarking, despite ongoing research efforts. …”
Get full text

The correlation between airborne pollen and asthma in children: a systematic review and meta-analysis by Xiaoya Wang, Bo Liu, Yujie Yang, Jimin Li, Ziyan Tian, Jinwei He, Yuanxia Li

“…EndNote X8 and Excel 2021 were used for data management and screening, while Stata 15 was used for statistical analysis.ResultsA total of 9 articles were included in this meta-analysis, from 2007 to 2024, with a total sample size of 87,270 children. The pooled analysis showed that airborne pollen exposure was significantly associated with the risk of childhood asthma (OR = 1.23, 95% CI: 1.13–1.33, P < 0.001). …”
Get full text

Identification of long noncoding RNAs (lncRNAs) and co-transcriptional analysis of mRNAs and lncRNAs in transcriptomes of Anopheles gambiae by Jiannong Xu, Kai Hu, Michelle M. Riehle, Vedbar S. Khadka

“…., sugar-feeding, blood-feeding, bacterial challenges, and Plasmodium infections).MethodsA Transcript Discovery module implemented in the CLC genomics workbench was used to identify lncRNAs from selected published RNA-seq datasets.ResultsAcross this pool of transcriptomes, 2684 unique lncRNA genes, comprising 4082 transcripts, were identified. …”
Get full text

Efficacy of sacituzumab govitecan versus treatment of physician’s choice in previously treated HR+ and HER2− mBC: a meta-analysis of TROPiCS-02 and EVER-132-002 trials by Oleg Gluz, Binghe Xu, Rita Nanda, Anandaroop Dasgupta, Ankita Kaushik, Wendy Verret, Akanksha Sharma, Barinder Singh, Hope S. Rugo

“…In the overall meta-analytic model, SG showed a significant improvement over TPC in PFS (hazard ratio (HR), 0.62 (95% confidence interval (CI): 0.50–0.77); p  < 0.001) and OS (HR, 0.66 (95% CI: 0.55–0.80); p  < 0.001). Similar patterns in efficacy were observed in both fast-progressors as well as patients previously treated with CDK4/6i. …”
Get full text

Wealth-based inequality in underweight among Scheduled Tribe women in India: a regional analysis by Anshika Singh, Aditya Singh, Mahashweta Chakrabarty, Shivani Singh, Pooja Tripathi

“…This study aims to explore trends and patterns of wealth-based inequalities in underweight prevalence among Scheduled Tribe (ST) women across various regions of India. …”
Get full text

Distribution of macrozoobenthic taxa - potential indicators of vulnerable marine ecosystems in the western part of Bering Sea. 1. Anadyr Bay area by Victor A. Nadtochy, Nickolay V. Kolpakov, Ilya A. Korneichuk

“…On the contrary, barnacles, sponges and sea squirts have similar distribution of the biomass, being complementary species. Distribution patterns of all species-indicators are stable for many decades. …”
Get full text

The Possible Influence of Atmospheric Circulation and North Atlantic Sea Surface Temperature Anomaly on the Winter Cold Wave Frequency in the Southern China by Feng JIANG, Liping LI

“…Based on the daily minimum temperature station data provided by the National Meteorological Information Centre from 1980 to 2022， the month-by-month reanalysis data of the NCEP/NCAR， and the monthly Sea Surface Temperature （SST） data from the NOAA， by using EOF， simple linear regression and T-N wave flux methods， the main anomalous spatial and temporal characteristics of winter cold wave frequency in the southern China are studied， and the influence mechanisms of atmospheric circulation and winter Atlantic Sea Surface Temperature Anomaly （SSTA） on it are also analyzed.The results show that： （1） The large value areas of winter cold wave frequency are mainly located in the eastern and central of the southern China， with an approximately "inverse C" distribution.There are three main frequency anomalous modes， namely， regionally consistent anomaly， north-south antiphase anomaly and tripole anomaly patterns according to the EOF analysis， among which the regionally consistent anomaly reflects the overall anomalous spatial and temporal characteristics of the winter cold wave frequency in the southern China.（2） The negative phase of the North Atlantic Oscillation （NAO）， the strong Caspian Sea - Tibetan Plateau ridge and the East Asian Trough located to the north and to the east， the weak in the north and strong in the south of the Siberian High， the strong temperate jet and the weak subtropical jet are the key circulation systems affect the winter cold wave frequency in the southern China.The cold air pool is located in the Western Siberia.The high and low level circulation systems cooperate together to make the cold air from Western Siberia move southward to the vicinity of the Caspian Sea， and then transport eastward along the northern side of the Tibetan Plateau， then move southward into the southern China along the eastern side of the Tibetan Plateau， resulting in the increase of the winter cold wave frequency in the whole southern China.（3）In winter， the “+”“-”“+” tripolar SSTA in the North Atlantic can stimulate the -NAO atmospheric circulation anomalies through the exchange of heat fluxes between air and sea and the Rossby wave energy anomalies.The Rossby wave energy propagates from the North Atlantic to East Asia along the south and north two paths， and stimulates the corresponding anomalous waves， which enhance the key circulation systems in the north and south affecting the cold wave frequency in the southern China.When the North Atlantic SSTA exhibits an inverse "C" anomaly in spring， and there is a trend of developing into a “+”“-”“+” tripolar pattern in summer and autumn， the winter cold wave frequency in the southern China can be predicted to more.…”
Get full text

Macrophage Infiltration Correlated with IFI16, EGR1 and MX1 Expression in Renal Tubular Epithelial Cells Within Lupus Nephritis-Associated Tubulointerstitial Injury via Bioinformat... by Tian M, Tang M, Chen C, Lin Y, Chen H, Xu Y

“…Ming Tian,1,2,&ast; Min Tang,1,2,&ast; Caiming Chen,1– 3,&ast; Yufang Lin,1,2 Hong Chen,4 Yanfang Xu1– 3 1Department of Nephrology, Blood Purification Research Center, the First Affiliated Hospital, Fujian Medical University, Fuzhou, People’s Republic of China; 2Fujian Clinical Research Center for Metabolic Chronic Kidney Disease, the First Affiliated Hospital, Fujian Medical University, Fuzhou, People’s Republic of China; 3Department of Nephrology, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350212, People’s Republic of China; 4Department of Pathology, the First Affiliated Hospital, Fujian Medical University, Fuzhou, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Hong Chen; Yanfang Xu, Email fychenhong@126.com; xuyanfang99@hotmail.comObjective: A comprehensive bioinformatics analysis was conducted to investigate potential new diagnostic biomarkers and immune infiltration characteristics associated with tubulointerstitial injury in lupus nephritis (LN), and to examine possible correlations between key genes and infiltrating immune cells.Methods: The GSE32591, GSE113342, and GSE200306 datasets were downloaded from the Gene Expression Omnibus database and differentially expressed genes (DEGs) were identified in the pooled dataset. Support vector machine-recursive feature elimination analysis and the least absolute shrinkage and selection operator regression model were used to screen for possible markers, and the compositional patterns of the 22 types of immune cell fractions in LN were determined using CIBERSORT. …”
Get full text

The Role of Reproductive Modes in Shaping Genetic Diversity in Polyploids: A Comparative Study of Selfing, Outcrossing, and Apomictic <i>Paspalum</i> Species by A. Verena Reutemann, Mara Schedler, Diego H. Hojsgaard, Elsa A. Brugnoli, Alex L. Zilli, Carlos A. Acuña, Ana I. Honfi, Eric J. Martínez

“…Contrary to previous findings, selfing (<i>Paspalum regnellii</i> and <i>P. urvillei</i>) and outcrossing (<i>P. durifolium</i> and <i>P. ionanthum</i>) species exhibited similar phenotypic diversity patterns, with low intrapopulation variability and no morphological differentiation among populations. …”
Get full text

Intervention to Increase Condom Use Among Users of Sexually Transmitted Infection (STI) Self-Sampling Websites (Wrapped): Feasibility Randomized Controlled Trial by Katie Newby, Kayleigh Kwah, Lauren Schumacher, Rik Crutzen, Louise L Jackson, Stephen Bremner, Julia V Bailey, Katherine E Brown

“…There was some evidence that attrition was patterned by ethnicity and age in ways that compounded initial recruitment patterns. …”
Get full text