Network meta-analysis of erlotinib, gefitinib, afatinib and icotinib in patients with advanced non-small-cell lung cancer harboring EGFR mutations. by Wenhua Liang, Xuan Wu, Wenfeng Fang, Yuanyuan Zhao, Yunpeng Yang, Zhihuang Hu, Cong Xue, Jing Zhang, Jianwei Zhang, Yuxiang Ma, Ting Zhou, Yue Yan, Xue Hou, Tao Qin, Xiaoxiao Dinglin, Ying Tian, Peiyu Huang, Yan Huang, Hongyun Zhao, Li Zhang

“…<h4>Methods</h4>We searched electronic databases for eligible literatures. Pooled data on objective response rate (ORR), progression free survival (PFS), overall survival (OS) were calculated. …”
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Dual orexin receptor antagonists for the treatment of insomnia: systematic review and network meta-analysis by Rebeka Bustamante Rocha, Fernanda Ferreira Bomtempo, Gabriela Borges Nager, Giulia Isadora Cenci, João Paulo Mota Telles

“…Concerning TST, an apparent dose-dependent pattern was noticed, with higher doses relating to a longer TST. …”
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Changes in soil organic and inorganic carbon with elevation in a dry alpine rangeland of the northern Qinghai–Tibet Plateau by Q. Liu, A. Zhang, X. Li, J. Yin, Y. Zhang, O. J. Sun, O. J. Sun, Y. Jiang

“…<p>The spatial patterns of soil carbon (C) in water constrained alpine ecosystems have rarely been investigated. …”
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Mapping surface soil organic carbon in the coal–grain composite area: threshold and interaction effects of coal mining activities by Zhaoqi Wu, Xiangyang Feng, Yiyun Chen, Zihao Wu, Xinyu Bao, Xin Zou

“…However, underground coal mining causes surface subsidence, farmland degradation, and a decline in the SOC pool, severely threatening soil security and long-term crop productivity. …”
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Anthropogenic Drivers of Small-Island Effects in Urban Remnant Woody Plants by Di Kong, Kai Wang, Lin Dong, Jinming Yang, Zhiwen Gao, Hong Liang

“…The positive relationship between species richness and area is a fundamental principle in ecology. However, this pattern deviates on small islands, where species richness either changes independently of area or increases at a slower rate—a phenomenon known as the Small-Island Effect (SIE). …”
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PO25 | Baseline thrombin generation test does not predict thrombotic events in acute leukemia: a monocentric prospective study

“…Despite most of the cohort showing a pattern of hypercoagulability, only 8 patients (7.2%) developed thrombotic complications, all of which were associated with central venous catheter placement. …”
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Integrity of Narrow Epithelial Tubes in the C. elegans Excretory System Requires a Transient Luminal Matrix. by Hasreet K Gill, Jennifer D Cohen, Jesus Ayala-Figueroa, Rachel Forman-Rubinsky, Corey Poggioli, Kevin Bickard, Jean M Parry, Pu Pu, David H Hall, Meera V Sundaram

“…The PAN domains are both necessary and sufficient to confer a cyclic pattern of duct lumen localization that precedes each molt, while the ZP domain is required for lumen integrity. …”
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Does partial replacement of corn with glycerin in beef cattle diets affect in vitro ruminal fermentation, gas production kinetic, and enteric greenhouse gas emissions? by Pedro Del Bianco Benedeti, Mozart Alves Fonseca, Teshome Shenkoru, Marcos Inácio Marcondes, Eduardo Marostegan de Paula, Lorrayny Galoro da Silva, Antonio Pinheiro Faciola

“…Glycerin had greatest CH4 production, lag time, and maximum gas volume of the first pool (P < 0.05). However, the maximum gas volume of the second pool was greatest for corn (P < 0.05), and similar between glycerin and starch. …”
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Diversity of questing ticks and prevalence of tick-associated pathogens in Khao Kheow-Khao Chomphu Wildlife Sanctuary, Chon Buri, Thailand by Wittawat Wechtaisong, Chalida Sri-in, Kritsada Thongmeesee, Elizabeth Riana, Thuong Thi Huyen Bui, Lyric C. Bartholomay, Sonthaya Tiawsirisup

“…Seven tick species were molecularly identified: Haemaphysalis lagrangei, H. wellingtoni, H. shimoga, H. obesa, Dermacentor auratus, Rhipicephalus microplus, and Amblyomma integrum. Of 80 tick pools, Anaplasma, piroplasms (Babesia and Theileria), Bartonella, and Rickettsia were detected in 10% (8/80), 3.75% (3/80), 1.25% (1/80), and 3.75% (3/80) of tick pools, respectively. …”
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A highly diverse phytobenthic community along a short coastal reef gradient in northeastern Brazil by Sol de Maria César Ferreira, Lucas Assumpção Lolis, Pietro Martins Barbosa Noga, Helen Michelle de Jesus Affe, José Marcos de Castro Nunes

“…This study aimed to inventory the species of marine macroalgae and analyze the distribution and biomass patterns of their communities along a short coastal reef gradient in northeastern Brazil. …”
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Flea-borne Rickettsia species in fleas, Caldas department, Colombia by Carol B Colonia, Alejandro Ramírez-Hernández, Juliana Gil-Mora, Juan C Agudelo, Gabriel Jaime Castaño Villa, Camilo Pino, Paola Betancourt-Ruiz, Jorge E Pérez Cárdenas, Lucas S Blanton, Marylin Hidalgo

“…Restriction pattern was compatible with R. felis. R. typhi was not identified. …”
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Spatiotemporally weighted regression (STWR) for assessing Lyme disease and landscape fragmentation dynamics in Connecticut towns by Zhe Wang, Xiang Que, Meifang Li, Zhuoming Liu, Xun Shi, Xiaogang Ma, Chao Fan, Yan Lin

“…The integration of data-driven and model-driven approaches in this study delivers a robust framework that combines empirical pattern detection with theoretical insight, enhancing the robustness and predictive power of ecological studies.…”
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Exploring the Hemp Virome and Assessing Hemp Germplasm for Resistance to an Emerging Pathogen by Laine Hackenberg, Jinlong Han, Jacob MacWilliams, Marylee L. Kapuscinski, Mark Stenglein, Rich Fletcher, Punya Nachappa

“…High-throughput sequencing revealed a total of seven viruses across both years from 48 pooled samples: alfalfa mosaic virus, beet curly top virus (BCTV), cannabis cryptic virus, cannabis sativa mitovirus 1, grapevine line pattern virus, opuntia umbra-like virus, and tomato bushy stunt virus. …”
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Exploring the Relationship Between Adipocytokines and Endometrial Cancer: Identifying Correlations With Clinico‐Pathological Prognostic Factors by Irene Ray, Carla S. Möller‐Levet, Agnieszka Michael, Simon Butler‐Manuel, Jayanta Chatterjee, Anil Tailor, Ben Haagsma, Izhar Bagwan, Lisiane B. Meira, Patricia E. Ellis

“…Results Using qRT‐PCR analysis, endometrial cancer tissues (n = 39) exhibited higher expression levels of adiponectin, leptin, IL6, TNFα, and their receptors, IL6R and TNFRSF1A/B, compared to the calibrator sample, which consisted of five pooled benign endometrial control samples. Intriguingly, the adiponectin receptors, ADIPOR1 and ADIPOR2 demonstrated opposing correlations with cancer characteristics such as grade, histology, LVSI, and microcystic elongated and fragmented (MELF) pattern. …”
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Differential Effect of Sex on Mortality According to Age in Heart Failure by Yoonpyo Lee, Minjae Yoon, Dong‐Ju Choi, Jin Joo Park

“…Methods and Results We pooled data from the KorHF (Korea Heart Failure) and the KorAHF (Korean Acute Heart Failure) registries including 3200 patients between 2005 and 2009 and 5625 patients between 2011 and 2014, respectively, hospitalized for acute heart failure in Korea. …”
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Altered functional connectivity density in the brains of hemodialysis end-stage renal disease patients: An in vivo resting-state functional MRI study. by Yan Shi, Chaoyang Tong, Minghao Zhang, Xiaoling Gao

“…<h4>Conclusion</h4>Our findings revealed abnormal intrinsic dysconnectivity pattern of salience network-related regions in ESRD patients from the whole brain network perspective. …”
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Healthy days at home and prognosis of older adults with cancer and non-cancer serious life-limiting illnesses by Oluwaseun J. Adeyemi, Nina Siman, Allison M. Cuthel, Keith S. Goldfeld, Corita R. Grudzen

“…Each unit increase in Gagne index score was associated with a 6.0% decrease in the rate of HDaH (aRR: 0.94; 95% CI: 0.94 to 0.94), a pattern observed in both cancer and non-cancer groups. …”
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Time Series Data Provide Insights into the Evolution and Abundance of One of the Most Abundant Viruses in the Marine Virosphere: The Uncultured Pelagiphages vSAG 37-F6 by Marina Vila-Nistal, Ramiro Logares, Josep M. Gasol, Manuel Martinez-Garcia

“…We explored the temporal dynamics of vSAG 37-F6, assessing periodic fluctuations in abundance and evolutionary patterns using long- and short-term data series. In the long-term series (7 years), metagenomics showed negative selection acting on all viral genes, with a highly conserved overall diversity over time composed of a pool of yearly emergent, highly similar novel strains that exhibited a seasonal abundance pattern with two peaks during winter and fall and a decrease in months with higher UV radiation. …”
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Effects of Different Preparations Containing Selenium on Selenium Status and Reproductive Performance of Common Carp (Cyprinus carpio L.) Broodstock by Jovanović Ivan B., Valčić Olivera, Gvozdić Dragan, Milanović Svetlana

“…Plasmatic glutathione peroxidase activity in supplemented groups increased from 4.41±1.15 to 7.73±2.26 μkat/L and plateaued until day 30. A similar pattern was observed for erythrocyte glutathione peroxidase activity, ranging from 54.51±15.45 μkat/L (day 1) to 80.72± 6.82 μkat/L (day 30). …”
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Multiple sensors provide spatiotemporal oxygen regulation of gene expression in a Rhizobium-legume symbiosis. by Paul J Rutten, Harrison Steel, Graham A Hood, Vinoy K Ramachandran, Lucie McMurtry, Barney Geddes, Antonis Papachristodoulou, Philip S Poole

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