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141
Genetic Diversity of Marrubium Species from Zagros Region (Iran), Using Inter Simple Sequence Repeat Molecular Marker
Published 2018-01-01“…Analysis of molecular variance detected low quantities of gene variation among species (18%) from which high proportion of variation presented among populations within species (82%). …”
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142
First genome-wide association study on anxiety-related behaviours in childhood.
Published 2013-01-01“…Affymetrix GeneChip 6.0 DNA arrays were used to genotype nearly 700,000 single-nucleotide polymorphisms (SNPs), and IMPUTE v2 was used to impute more than 1 million SNPs. …”
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143
A causal inference study exploring the impact of iron status on the risk of thyroid cancer based on two-sample mendelian randomization
Published 2025-04-01“…Method Utilizing iron status-related Single Nucleotide Polymorphisms as instrumental variables, the research analyzed summary data on iron status and thyroid cancer from Genome-Wide Association Studies following the Two-sample Mendelian randomization guidelines, primarily using the Inverse-variance weighted method, with Mendelian randomization-Egger method, weighted median method, simple mode, and weighted mode as supplementary analyses. …”
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144
Genomic prediction in Persian walnut: Optimization levers according to genetic architecture of complex traits
Published 2025-06-01“…Selecting the top 1% of 364,275 SNPs based on their variance (∼3600 SNPs) was sufficient to achieve accurate predictions. …”
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145
Complex variation in measures of general intelligence and cognitive change.
Published 2013-01-01“…Measures of crystallised (gc) and fluid intelligence (gf) in late adulthood (64-79 years) were available for 1806 individuals genotyped for 549,692 autosomal single nucleotide polymorphisms (SNPs). The same individuals were tested at age 11, enabling us the rare opportunity to measure cognitive change across most of their lifespan. 547,750 SNPs ranked by position are divided into 10, 908 overlapping regions of 101 SNPs to estimate the genetic variance each region explains, an approach that resembles classical linkage methods. …”
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146
The causal relationship between biological function of mitochondria and chronic kidney disease: a Mendelian randomization study
Published 2025-05-01“…Regression analysis demonstrated that the included single-nucleotide polymorphisms (SNPs) did not exhibit pleiotropy (<italic>P</italic>>0.05). …”
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147
Influence of puberty timing on adiposity and cardiometabolic traits: A Mendelian randomisation study.
Published 2018-08-01“…In 2-sample MR analyses using 234 polymorphisms and inverse variance weighted (IVW) regression, each year later age at menarche was associated with -0.81 kg/m2 of adult BMI (or -0.17 SD units, 95% CI -0.21, -0.12; P = 4.00 × 10-15). …”
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148
Association between Helicobacter pylori antibodies and otolaryngological diseases
Published 2024-11-01“…Methods: Single-nucleotide polymorphisms associated with 7 H. pylori antibodies (IgG, CagA, Catalase, GroEL, OMP, UREA and Vac A) served as instrumental variables. …”
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149
Exploring the causal association between rheumatoid arthritis and the risk of cervical cancer: a two-sample Mendelian randomization study
Published 2024-01-01“…Genetic tool variables, specifically single-nucleotide polymorphisms closely linked to rheumatoid arthritis, were chosen for analysis. …”
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150
Genetic Causality of Hypothyroidism and Adverse Pregnancy Outcomes: A Combined Mendelian Randomisation Study and Bioinformatics Analysis
Published 2024-12-01“…The inverse variance weighting method was primarily used in the analysis. …”
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151
A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose.
Published 2009-03-01“…Prior work established that approximately 30% of the dose variance is explained by single nucleotide polymorphisms (SNPs) in the warfarin drug target VKORC1 and another approximately 12% by two non-synonymous SNPs (*2, *3) in the cytochrome P450 warfarin-metabolizing gene CYP2C9. …”
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152
Assessing the utility of genomic selection to breed for durable Ascochyta blight resistance in chickpea
Published 2025-06-01“…Bayesian modeling identified six major QTL explaining 33% of the genetic variance for AB resistance, with the remaining variance explained by minor effect genes. …”
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153
Causal relationship between type I diabetes mellitus and atrial fibrillation: A Mendelian randomization study
Published 2025-04-01“…Methods: Using publicly available genome-wide association studies data, we selected single nucleotide polymorphisms significantly associated with type 1 diabetes mellitus as instrumental variables. …”
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154
Causal relationship between citrate and gestational diabetes mellitus: a two-sample Mendelian randomization analysis
Published 2025-12-01“…The research data is derived from the OpenGWAS and FinnGen databases, with single nucleotide polymorphisms (SNPs) related to citrate levels and the incidence of GDM selected as analytical tools. …”
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155
What is the contribution of two genetic variants regulating VEGF levels to type 2 diabetes risk and to microvascular complications?
Published 2013-01-01“…Recently, a genome-wide association study identified two common single nucleotide polymorphisms (SNPs; rs6921438 and rs10738760) explaining nearly half of the variance in circulating VEGF levels. …”
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156
A Study of Maize Genotype–Environment Interaction Based on Deep K-Means Clustering Neural Network
Published 2025-02-01“…Based on this delineation result, the interactions between genotypes and the environment on maize were investigated and clarified using genome-wide association analysis (GWAS) and analysis of variance (ANOVA). Ultimately, through the analysis of maize field trial data from 2020 to 2021, we identified up to 108 single-nucleotide polymorphisms (SNPs) in 2020 and 153 SNPs in 2021 that exerted significant effects on maize yield and exhibited strong correlations with environmental factors, including temperature, cumulative precipitation, and cumulative sunshine duration.…”
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157
Genome-wide association study and haplotype analyses reveal the genetic architecture of agronomic traits and sugars in sweet sorghum
Published 2025-07-01“…This study identified 21 significant quantitative trait nucleotides (QTNs) for the studied traits using the three (compressed)-variance component multi-locus random- SNP-effect mixed linear model (3VmrMLM), which were colocalized with previously reported quantitative trait loci (QTLs). …”
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158
Association between Chronic Hepatitis B and Osteoporosis: a two-sample mendelian randomization study
Published 2025-03-01“…The single-nucleotide polymorphisms (SNPs) associated with CHB were selected as instrumental variables (IVs). …”
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159
Assessment of Microsatellite Genetic Diversity of Cultured Eriocheir sinensis Populations from Jiangsu and Anhui
Published 2024-12-01“…PIC_CALC 0.6 software calculates polymorphism information content (PIC). Analysis of molecular variance (AMOVA) and the coefficient of genetic differentiation (Fst) were performed using Arlequin 3.5 software. …”
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160
Assessing Causality Between Endocrine, Nutritional, and Metabolic Disease and Pulmonary Tuberculosis: A Mendelian Randomization Study
Published 2025-06-01“…Methods We obtained single nucleotide polymorphisms linked to ENMD, ENMD‐related diseases, and clinical features, as well as PTB, from the IEU OpenGWAS project. …”
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