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Branched-chain amino acids levels associated with risk of erectile dysfunction: A Mendelian randomization analysis
Published 2025-02-01“…The primary method used to assess causal associations was the inverse variance-weighted (IVW) method, supplemented by MR-Egger, weighted median, and simple median analyses. …”
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The gut microbiome and ovarian cysts: a mendelian randomization study
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Whole genome sequencing reveals the genetic diversity and structure of Leptosphaeria maculans populations from the Western Cape province of South Africa
Published 2025-04-01“…A total of 27 419 informative single nucleotide polymorphisms was used to investigate the genetic diversity and structure of the pathogen population. …”
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Thyroid function and hepatic fibrosis/cirrhosis: a two-sample Mendelian randomization study
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Lipid metabolism-associated metabolites on cardiovascular diseases: a two-sample Mendelian randomized study
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Lipid have a direct effect on multiple myeloma: a Mendelian randomization study
Published 2024-06-01“…These IVs underwent MR analysis, adhering to strict criteria for correlation, independence, and the exclusion of confounders. The inverse variance weighted (IVW) method, MR-Egger method, weighted median (WM) method, and simple median were utilized for MR analysis assessment, alongside Cochran’s Q test, MR-Egger intercept, MR-Pleiotropy Residual Sum and Outlier (MR-RESSO) method, and leave-one-out analysis for evaluating heterogeneity, multiplicity, and instrumental bias.ResultsThe study identified 88 significant, independent single nucleotide polymorphisms (SNPs) as IVs for MR analysis, each with an F-statistic value above 10, indicating robustness against weak instrument bias. …”
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Development and Application of SSR Markers for <i>Aquilaria sinensis</i> on the Basis of Whole-Genome Resequencing Data
Published 2025-04-01“…Ultimately, 20 primer pairs with stable amplification and high polymorphism were selected, of which 11 exhibited high polymorphism (polymorphic information content: 0.554–0.688). …”
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Renal function and risk of dementia: a Mendelian randomization study
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GENETIC ASPECTS OF PANNICULITIS IN A RUSSIAN POPULATION: A PILOT STUDY
Published 2016-12-01“…In the WCP group, analysis of variance showed an association of IL-1RA gene VNTR polymorphism with the intensity of pain, assessed by the visual analogue scale. …”
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Genetic Diversity and Population Structure of Wild Ancient <i>Camellia tetracocca</i> in Pu’an, Guizhou, China
Published 2025-06-01“…Analysis of molecular variance indicated that 91.59% of the genetic variation occurred within the subpopulations, suggesting limited differentiation. …”
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Causal effects of lipid-lowering drugs on skin diseases: a two-sample Mendelian randomization study
Published 2024-09-01“…The inverse-variance weighted (IVW) method was used to determine causal relationships. …”
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Association between autoimmune diseases and myelodysplastic syndrome:a Mendelian randomization study
Published 2024-12-01“…Therefore, we employed Mendelian randomization (MR) to examine whether genetically predicted susceptibility to ten autoimmune diseases is associated with the risk of MDS.Methods: Single nucleotide polymorphisms (SNPs) significantly associated with 10 autoimmune diseases were extracted from the summary statistics of European genome-wide association studies (GWAS). …”
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慢性肾病与卒中的因果关系:一项两样本双向孟德尔随机化研究Causality between Chronic Kidney Disease and Stroke: A Two-Sample Bidirectional Mendelian Randomization Study...
Published 2024-12-01“…方法 正向研究以CKD为暴露因素,卒中为结局变量,获取CKD和卒中的全基因组关联分析数据,筛选出与CKD显著相关的单核苷酸多态性(single nucleotide polymorphism,SNP)作为工具变量。反向研究则筛选与卒中密切相关的SNP作为工具变量,CKD作为结局变量。…”
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Analysis of genetic diversity in the natural population of Emmenopterys henryi using RAPD
Published 2007-01-01“…Among which, 100 bands were polymorphic and the percentage of polymorphic bands (PPB) was 54.95%. …”
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Genetic Diversity and Population Structure of Fusarium oxysporum f. sp. cepae, the Causal Agent of Fusarium Basal Plate Rot on Onion using RAPD Markers
Published 2010-09-01“…A total of 116 single spore isolates of Fusarium oxysporum f. sp. cepae representing seven populations from Turkey and one population from Colorado, USA were subjected to molecular marker analysis using Random amplified polymorphic DNA (RAPD) technique. Using eleven polymorphic primers, 110 RAPD fragments were obtained with an average of 10 polymorphic bands per primer. …”
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Genetic Diversity of Tef [Eragrostis tef (Zucc.)Trotter] as Revealed by Microsatellite Markers
Published 2021-01-01“…A total of 314 alleles were detected with an average of 14.5 alleles per locus and amplicon size ranged from 90 bp–320 bp. The mean value of polymorphic information content (PIC) was 0.87, appearing polymorphic for all loci. …”
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