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341
Association between chronic obstructive pulmonary disease and osteoporosis: Mendelian randomization combined with bibliometric analysis
Published 2025-02-01“…Methods Single nucleotide polymorphisms (SNPs) that have been found to be strongly associated with COPD were used as instrumental variables (IVs) in MR Analysis. …”
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342
Causal associations between liver function biomarkers and prostate cancer risk in European and East Asian populations: a univariate, multivariable, and bidirectional Mendelian Rand...
Published 2025-03-01“…Methods Single nucleotide polymorphisms (SNPs) significantly associated with liver function markers and PCa were selected from large-scale genome-wide association studies (GWAS) as instrumental variables (IVs). …”
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343
The causal relationships between mitochondria and six types of cancer: a Mendelian randomization study
Published 2025-04-01“…Methods Two-sample MR analysis was performed using the inverse variance weighted (IVW) method, with MR-Egger regression and weighted median as complementary approaches. …”
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344
Evaluating the causal effects between Grave’s disease and diabetes mellitus: a bidirectional Mendelian randomization study
Published 2024-11-01“…Finally, MVMR analysis was conducted to investigate the probable relationship between DM and indicators for thyroid function like TPO, Tg, and TSH. The inverse variance weighting (IVW) was used as the main method. …”
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345
Associations between psoriasis and risk of 33 cancers: a Mendelian randomization study
Published 2025-05-01“…Method Forty-nine independent single-nucleotide polymorphisms (SNPs) significantly associated with psoriasis were extracted as instrumental variables from a large-scale meta-analysis study of genome-wide association study (GWAS) for psoriasis. …”
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346
Genetic Linkage Map Construction and QTL Mapping for Juvenile Leaf and Growth Traits in <i>Camellia oleifera</i>
Published 2024-12-01“…Identifying single nucleotide polymorphisms (SNPs) associated with target traits, and applying molecular marker-assisted selection (MAS) for these traits, can thereby shorten the breeding cycles and amplify the breeding efficiency. …”
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347
Association of nociceptive, neurocognitive, psychological and genetic profile on conditioned pain modulation in women with migraine: protocol for a case–control study
Published 2025-08-01“…Clinical variables (disability, pain), processing (sensitisation-associated, neuropathic-like symptoms), psychological/emotional (anxiety, depression, sleep quality, catastrophising), neurocognitive (attention), executive functions (memory, mental inhibition, speed processing) and genetics (Val158Met polymorphism rs4680 gene) will be assessed in all subjects by healthcare professionals. …”
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348
Genetic diversity analysis and DNA fingerprinting of different populations of largemouth bass (Micropterus salmoides) in China with fluorescence-labeled microsatellite markers
Published 2025-05-01“…The analysis of molecular variance (AMOVA) revealed that 83.77% of genetic variation was found within individuals, with only 16.23% attributed to differences among populations. …”
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349
A Two-Way Mendelian Randomization Analysis on the Link between Thyroid Activity Function and Coronary Atherosclerosis
Published 2024-12-01“…Following the application of strict criteria to eliminate linkage disequilibrium, palindromic sequences, and heterozygous alleles, a bidirectional Mendelian Randomization (MR) analysis was conducted between the thyroid gland and coronary atherosclerosis using inverse variance weighting (IVW), weighted median (WM), and MR-Egger techniques. …”
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350
Multiple anthropometric measures and proarrhythmic 12-lead ECG indices: A mendelian randomization study.
Published 2023-08-01“…Data source GWAS studies were performed between 2018 and 2022 in predominantly European ancestry individuals. Inverse-variance weighted MR was used for primary analysis; weighted median MR and MR-Egger were used as sensitivity analyses. …”
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351
How do immune cells shape type 1 diabetes? Insights from Mendelian randomization
Published 2024-12-01“…Inverse variance weighted was used as the main method for the MR analysis. …”
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352
The Causal Relationship between Angina Pectoris and Gout Based on Two Sample Mendelian Randomization
Published 2024-01-01“…Based on genome-wide association studies, single nucleotide polymorphisms (SNPs) that were closely associated with gout were selected from the UK Biobank–Neale Lab (ukb-a-107) as genetic instrumental variables. …”
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353
Associations between insomnia and pregnancy and perinatal outcomes: Evidence from mendelian randomization and multivariable regression analyses.
Published 2022-09-01“…Main MR analyses used inverse variance weighting (IVW), with weighted median and MR-Egger as sensitivity analyses. …”
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354
Sjögren’s syndrome is associated with a reduction in the surface area of the right caudal anterior cingulate gyrus
Published 2025-07-01“…Methods A two-sample Mendelian randomization (MR) analysis was conducted using four single-nucleotide polymorphisms (SNPs) associated with SS. Summary data from genome-wide association studies (GWAS) on SS and brain cortical structure were analyzed using inverse-variance weighted (IVW), MR-Egger, and weighted median (WM) methods. …”
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355
Assessing the causal effect of inflammation‐related genes on myocarditis: A Mendelian randomization study
Published 2025-02-01“…The GWAS data (finn‐b‐I9 MYOCARD) contained single nucleotide polymorphisms (SNPs) data from 117 755 myocarditis samples (16 379 455 SNPs, 829 cases vs. 116 926 controls). …”
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356
Mendelian randomization reveals probucol’s preventive role in Behçet’s disease via circulating metabolites
Published 2025-03-01“…To ensure the robustness and validity of our findings, we employed several MR methods, including the Inverse Variance Weighted (IVW) approach, heterogeneity tests, and pleiotropy analysis. …”
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357
Spleen volume in relation to ulcerative colitis and Crohn’s disease: a Mendelian randomization study
Published 2025-02-01“…Single nucleotide polymorphisms (SNPs) associated with SV were used as instrumental variables. …”
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358
Genome-Wide Identification of Wheat Gene Resources Conferring Resistance to Stripe Rust
Published 2025-06-01“…The genotyping applied a 55K wheat single-nucleotide polymorphism (SNP) array. A genome-wide association study (GWAS) identified 14 QTL using a significance threshold of <i>p</i> ≤ 0.001, which distributed on chromosomes 1B (4), 1D (2), 2B (4), 6B, 6D, 7B, and 7D (4 for CYR33, 7 for CYR34, 3 for mixed <i>Pst</i> races), explaining 6.04% to 18.32% of the phenotypic variance. …”
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359
Mapping of a Quantitative Trait Locus for Stay-Green Trait in Common Wheat
Published 2025-02-01“…To clarify the SG loci carried by CH7034 and obtain linked molecular markers, in this study, a recombinant inbred line (RIL) population derived from the cross between CH7034 and non-SG SY95-71 was genotyped using the Wheat17K single-nucleotide polymorphism (SNP) array, and a high-density genetic map covering 21 chromosomes and consisting of 2159 SNP markers was constructed. …”
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360
Genetically predicted gut bacteria, circulating bacteria-associated metabolites and pancreatic ductal adenocarcinoma: a Mendelian randomisation study
Published 2024-10-01“…Single Nucleotide Polymorphisms (SNPs) associated by Genome-Wide Association Studies (GWAS) with circulating levels of 109 of these metabolites were collated from Pubmed and the GWAS catalogue. …”
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