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221
Genome-wide discovery of InDels and validation of PCR-Based InDel markers for earliness in a RIL population and genotypes of lentil (Lens culinaris Medik.).
Published 2024-01-01“…The systematic identification of insertion/deletion (InDel) length polymorphisms from the entire lentil genome can be used to map the quantitative trait loci (QTL) and also for the marker-assisted selection (MAS) for various linked traits. …”
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222
Causal relationship between mental disorders and hypercholesterolemia: a Mendelian randomization analysis
Published 2025-04-01“…Single nucleotide polymorphisms (SNPs) strongly associated with mental disorders were chosen as instrumental variables, and hypercholesterolemia was used as outcome variable. …”
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223
The impact of synapsin III gene on the neurometabolite level alterations after single-dose methylphenidate in attention-deficit hyperactivity disorder patients
Published 2016-05-01“…Both rs133945G>A and rs133946C>G polymorphisms were found to statistically significantly affect the alteration of NAA levels in response to Mph in dorsolateral prefrontal cortex with two-way repeated measure of analysis of variance. …”
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224
Genetic diversity and population structure of the indigenous goat population in Tunisia's northwest
Published 2025-06-01“…Analysis of molecular variance (AMOVA) revealed that genetic differences within the population explained 92.4 % of the variation. …”
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225
Genetic diversity and population structure of cowpea mutant collection using SSR and ISSR molecular markers
Published 2024-12-01“…Genetic variation, as assessed by analysis of molecular variance, mostly indicates higher genetic diversity within the population than among populations. …”
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226
Noise and the risk of tinnitus: A two‐sample Mendelian randomized study
Published 2025-06-01“…Methods We extracted single nucleotide polymorphisms (SNPs) associated with noise and tinnitus from a large genome‐wide association study (GWAS) of European individuals. …”
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227
Association of metformin with risk of digestive tract cancers from a drug target mendelian randomization and cell experiments
Published 2025-05-01“…The inverse variance-weighted method (IVW) was the most important method. …”
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228
Exploring the association between systemic lupus erythematosus and osteonecrosis by Mendelian randomization analysis
Published 2025-04-01“…In this study, a total of 45 single nucleotide polymorphisms (SNPS) data associated with SLE from publicly available genome-wide association study (GIS) datasets were selected for magnetic resonance estimation using inverse-variance weighting, MR-Eagle method and weighted median method. …”
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229
Causal associations between 17 common autoimmune diseases and aortic diseases: a Mendelian randomization study
Published 2025-09-01“…The inverse-variance weighted (IVW) approach was primarily employed to estimate causal links between autoimmune and aortic diseases. …”
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230
Causal relationship between blood lipids and diabetic kidney disease:a Mendelian randomization study
Published 2025-01-01“…Steiger test was used to test directionality, and leave-one-out analysis was used to determine whether there was potential single nucleotide polymorphism.ResultsThe IVW method was used as the main analysis method. …”
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231
Improvement in genomic prediction of maize with prior gene ontology information depends on traits and environmental conditions
Published 2025-03-01“…It allows likely causal markers to account for a certain portion of genetic variance independently from the remaining markers. …”
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232
Discovering leaf and stripe rust resistance in soft red winter wheat through genome‐wide association studies
Published 2025-06-01“…Nine major QTL included QLrYr‐2A.1 linked to single‐nucleotide polymorphism S2A_20855466, which had the highest overall PV (30.8%) for response to both rust pathogens in the field. …”
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233
Assessing genetic causal relationship between milk fat content and chronic kidney disease: a two-sample Mendelian randomization study
Published 2025-12-01“…Single nucleotide polymorphisms (SNPs) significantly associated with milk fat content were identified following rigorous quality control procedures. …”
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234
Assessing the causality between pulmonary arterial hypertension and cancer: insights from Mendelian randomization
Published 2024-12-01“…Inverse-variance weighted (IVW) was used as the primary method for MR analysis, with sensitivity analyses including tests for heterogeneity and horizontal pleiotropy. …”
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235
Association between hypothyroidism and nephrotic syndrome: a bidirectional two-sample Mendelian randomization analysis
Published 2024-12-01“…Background There is a close clinical association between hypothyroidism and nephrotic syndrome (NS) was close, but whether there is genetic causality between the two is not known.Objective Using pooled data from a genome-wide association study (GWAS), the association between hypothyroidism and NS was explored via Mendelian randomization (MR) analysis.Methods Single-nucleotide polymorphisms (SNPs) associated with hypothyroidism (or NS) were screened as genetic instrumental variables (IVs) from pooled GWAS data, and inverse-variance weighting (IVW) was used for the main analysis to estimate causal effects, with MR-Egger, weighted median, and weighted mode used as complementary methods. …”
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236
Exploring the role of EBV ZEBRA antibody levels in papillary thyroid cancer risk and drug resistance
Published 2025-04-01“…For instrumental variable selection, we identified single nucleotide polymorphisms (SNPs) strongly associated with EBV ZEBRA antibody levels (exposure traits) using a discovery GWAS of 8191 White British individuals. …”
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237
The causal relationships between gut microbiota and venous thromboembolism: a Mendelian randomization study
Published 2025-02-01“…Firstly, single nucleotide polymorphisms (SNPs) locus-wide significantly (P < 1.0 × 10− 5) related with gut microbiome abundance were extracted from large genome-wide analysis (GWAS) meta-analysis summary data. …”
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238
Correlation of air pollution and risk of sudden sensorineural hearing loss: a Mendelian randomization study
Published 2025-08-01“…The primary method used for MR analysis was the Inverse Variance Weighted (IVW) method, supplemented by various MR analyses method, including weighted median, simple mode, weighted mode, and MR-Egger, to ensure robustness. …”
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239
Causal Relationship Between Cerebrospinal Fluid Metabolites and Intervertebral Disc Disease: A Bidirectional Mendelian Randomization Study
Published 2025-06-01“…MR analysis employed single nucleotide polymorphisms (SNPs) closely associated with disease as instrumental variables (IVs). …”
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240
Systemic lupus erythematosus and epilepsy: A Mendelian randomization study
Published 2024-12-01“…Methods Single nucleotide polymorphisms (SNPs) linked to SLE were utilized as instrumental variables in MR analysis to assess their causal impact on epilepsy. …”
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