Ulcerative colitis increases the risk of atrioventricular block: evidence from a Mendelian randomized analysis by Wanqiong Shu, Guanghong Huang

“…We identified single nucleotide polymorphisms (SNP) associated with IBD as instruments, including IBD, ulcerative colitis (UC), and Crohn’s disease (CD). …”
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Exploring the Causal Relationship between Ibuprofen Use and Osteoarthritis Risk: A Mendelian Randomization Study by Yongzhi Jian, Yanmin Lyu, Said Hashemolhosseini

“…We conducted a two-sample MR analysis using four distinct OA GWAS datasets as outcomes and single-nucleotide polymorphisms (SNPs) associated with IBU metabolism as exposures. …”
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The antiviral efficacy of HIV-specific CD8⁺ T-cells to a conserved epitope is heavily dependent on the infecting HIV-1 isolate. by Srinika R F Ranasinghe, Holger B Kramer, Cynthia Wright, Benedikt M Kessler, Katalin di Gleria, Yonghong Zhang, Geraldine M Gillespie, Marie-Eve Blais, Abigail Culshaw, Tica Pichulik, Alison Simmons, Sarah L Rowland-Jones, Andrew J McMichael, Tao Dong

“…Recognition of the HIV-1 isolates by CTL was independent of clade-grouping but correlated with virus-specific polymorphisms in the epitope flanking region, which altered immunoproteasomal cleavage resulting in enhanced or impaired epitope generation. …”
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Effects of Hyperthyroidism on Venous Thromboembolism: A Mendelian Randomization Study by Fushi Han, Chunyang Zhang, Miao Xuan, Zhuangli Xie, Kunming Zhang, Ying Li

“…With single nucleotide polymorphisms (SNPs) as instrumental variables, the casual effects of genetically predicted TSH and FT4 and hypo- and hyperthyroidism on venous thromboembolism outcome were estimated through Mendelian randomization analysis methods (inverse variance weighted (IVW), MR-Egger, weighted median, simple mode, and weighted mode). …”
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Mapping QTLs associated with Barley seed germination under normal and drought stress conditions by zeinab taghizadeh, hossein sabouri, Hossein Hosseini, Moghaddam, Fallahi Hossein Ali, Mahnaz Katouzi

“…In general, twenty seven QTLs were detected for all traits. Total phenotypic variance explained by these QTLs varied from 8.6 to 37.3 percent. …”
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Inbreeding and Genetic Differentiation Among Geographic Populations of <i>Lactarius hatsudake</i> in Southwest China by Kuan Zhao, Mingwei Mao, Xianghua Wang, Jianping Xu

“…Five simple sequence repeat markers that demonstrated high polymorphism were developed and used to analyze the patterns of genetic variations within and among the eight geographic populations. …”
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Causal relationship between atopic dermatitis and infectious gastroenteritis: a bidirectional mendelian randomization study by XING Ke, LIU Yi, HOU Nan, ZHANG Haiyang

“…MR analysis was performed using inverse variance weighted (IVW), MR Egger's method, weighted median, weighted mode, and simple mode. …”
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Influence of Immune Cells and Circulating Inflammatory Cytokines on Pathological Scars: A Mendelian Randomization Study by Xu Y, Zhan W, Zhao J

“…The inverse-variance weighted (IVW) method was used as the main analytical method. …”
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Causal relationship between blood lipids and diabetic kidney disease：a Mendelian randomization study by Wang Hao-hao, Liu Hao-fei, Miao Shao-bo, Jia Run-ke, Ma Ji-wei

“…Steiger test was used to test directionality， and leave-one-out analysis was used to determine whether there was potential single nucleotide polymorphism.ResultsThe IVW method was used as the main analysis method. …”
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Mendelian randomization analysis of immune cell populations, serum metabolites and hepatocellular carcinoma risk by Wei Shen, Yuanying Zeng

“…The inverse variance weighted (IVW). method was primarily used for effect size estimation, with robustness verified through multiple sensitivity analysis methods including MR-Egger regression and weighted median method. …”
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Best linear unbiased prediction of genomic breeding values using a trait-specific marker-derived relationship matrix. by Zhe Zhang, Jianfeng Liu, Xiangdong Ding, Piter Bijma, Dirk-Jan de Koning, Qin Zhang

“…<h4>Background</h4>With the availability of high density whole-genome single nucleotide polymorphism chips, genomic selection has become a promising method to estimate genetic merit with potentially high accuracy for animal, plant and aquaculture species of economic importance. …”
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A Multiparent Advanced Generation Inter-Cross to fine-map quantitative traits in Arabidopsis thaliana. by Paula X Kover, William Valdar, Joseph Trakalo, Nora Scarcelli, Ian M Ehrenreich, Michael D Purugganan, Caroline Durrant, Richard Mott

“…These lines and the 19 founders were genotyped with 1,260 single nucleotide polymorphisms and phenotyped for development-related traits. …”
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Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression. by Michael S Cunnington, Mauro Santibanez Koref, Bongani M Mayosi, John Burn, Bernard Keavney

“…Single nucleotide polymorphisms (SNPs) on chromosome 9p21 are associated with coronary artery disease, diabetes, and multiple cancers. …”
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Causal effects of retinol and vitamin D on tongue cancer risk: a mendelian randomization study by Jiawei Zhang, Yake Lou, Hong Chen, Xiaofeng Huang

“…Methods Single nucleotide polymorphisms (SNPs) related to retinol, vitamin D and tongue cancer were obtained from the up-to-date genome-wide association study (GWAS) catalogue, which was screened for instrumental variables (IVs). …”
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Causal relationship between atherosclerosis and inflammatory bowel disease risk: a two-sample Mendelian randomization study by Wenjuan Guo, Na Peng, Shiyu Du

“…The causal links between atherosclerosis and IBD were evaluated using inverse-variance weighted (IVW) as the primary method. Leave-one-out analysis was utilized to evaluate whether the outcomes were attributable to any individual SNP correlated to sex hormones. …”
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Women’s early reproductive behaviors and postpartum depression: a two-sample Mendelian randomization study by Zhenyong Gao, Siyu Deng, Hongliang Zhu, Yong Yang, Ping Yang, Jianbin Du

“…We selected Single Nucleotide Polymorphisms (SNPs) from genome-wide association study (GWAS) studies targeting age at first sexual intercourse (AFS), age at first live birth (AFB), and age at last live birth (ALB), and age at menarche (AAM) as genetic instruments. …”
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Causal Associations Between Nitrogen Dioxide Exposure and Thyroid Nodules: a Two-Sample Mendelian Randomization Analysis by Chengxiang Liu, Sainan Li, Chen Zhu, Shan Chen, Juan Zhou, Hong Chen

“…Seven single nucleotide polymorphisms (SNPs) associated with NO₂ levels were chosen as instrumental variables (IVs). …”
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Causality between insulin use and malignant tumors of the digestive system: a two-sample mendelian randomized study by DengZhuo Chen, YongLi Ma, JingHui Li, Liang Wen, GuoSheng Zhang, ChengZhi Huang, XueQing Yao

“…The primary method of analysis was inverse variance weighting (IVW), supplemented by weighted median, MR-Egger regression, weighted mode and simple mode methods. …”
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Gene prediction of the relationship between iron deficiency anemia and immune cells by Xuanxuan Xu, Zhixia Li, Huimin Liu, Zhiping Huang, Tao Xiong, Yuanyan Tang

“…The primary method was inverse variance weighting (IVW), and auxiliary analyses were MR-Egger, weighted median, simple mode and weighted mode. …”
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Carnitine is causally associated with susceptibility and severity of sepsis: a Mendelian randomization study by Qingju Zhang, Xilong Liu, Qi Shen, Xingfang Wang, Jiaojiao Pang, Yuguo Chen

“…The inverse-variance weighted (IVW), MR-Egger, and weighted median methods were used to evaluate the causal relationship between exposure and outcomes. …”
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