Cowpea genetic diversity, population structure and genome-wide association studies in Malawi: insights for breeding programs by Michael M. Chipeta, John Kafwambira, Esnart Yohane

“…IntroductionThis study focuses on cowpea, a vital crop for smallholder farmers in sub-Saharan Africa, particularly in Malawi. …”
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Genome-Wide Dissection of Novel QTLs and Genes Associated with Weed Competitiveness in Early-Backcross Selective Introgression-Breeding Populations of Rice (<i>Oryza sativa</i> L.) by Kim Diane Nocito, Varunseelan Murugaiyan, Jauhar Ali, Ambika Pandey, Carlos Casal, Erik Jon De Asis, Niña Gracel Dimaano

“…This study aimed to develop rice cultivars competitive against jungle rice through selective breeding, focusing on early seed germination (ESG) and seedling vigor (ESV). …”
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Lipoprotein(a) molar concentrations rather than genetic variants better predict coronary artery disease risk and severity in Han Chinese population by Jie Li, Ben Ma, Qin Fang, Jing Wang, Yang Sun, Hu Ding, Yan Wang

“…However, most studies on Lp(a) associated genetic variants have focused on the Caucasian population currently. Our study aimed to test the associations among LPA genetic variants, Lp(a) concentrations, and CAD in a Han Chinese cohort. …”
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Integrative analysis of m6A-SNPs and single-cell RNA sequencing reveals key drivers of endocrine combined with CDK4/6 inhibitor therapy resistance in ER+ breast cancer by Ruijie Ming, Ruijie Ming, Han Zhang, Huan Wu, Fangbiao Zhan, Fangbiao Zhan, Xiaoping Huang, Xiaoping Huang, Huawen Liu, Huawen Liu

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Pharmacogenetics and Inflammatory Bowel Diseases in Adults and Children: Diagnosis and Treatment Prospects by S. Yu. Serebrova, A. B. Prokofiev, M. V. Zhuravleva, R. E. Kazakov, I. V. Suchinava, G. I. Gorodetskaya, N. N. Eremenko, N. B. Lazareva, L. R. Galstyan, E. A. Smolyarchuk, D. O. Kurguzova, A. O. Barkov

“…It names the main candidate genes, which, in the presence of their specific polymorphisms, indicate the occurrence of a high risk of inflammatory bowel disease. …”
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Role of Pharmacogenetic Testing in the Risk and Safety Assessment of Valproates: The Ethnic Aspect (Review) by N. A. Shnayder, V. V. Grechkina, V. V. Arkhipov, R. F. Nasyrova

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Genome-wide association studies for identifying genetic architecture of SGRQ in smoking population by Hao Xinying, Zhu Jun

“…The primary focus of the study is to identify genetic risk factors that determine susceptibility for COPD and COPD-related phenotypes with the goal of providing insight into clinically relevant COPD subtypes. …”
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Modern neurogenetic representations of MELAS syndrome. Clinical cases (the lecture) by A. V. Shatalin, E. V. Mukhina, A. S. Kotov, M. G. Amirkhanyan

“…Clinical cases, given in this lecture, supplement the piggy bank of genetically verified mitochondrial diseases leading to the development of polymorphic neurological disorders and characteristic neuroimaging picture, namely the appearance of polymorphic ischemic changes in the temporal, parietal or occipital regions of the brain, that do not correspond to the zones of the main vascular blood supply, as the basis for the formation of such focus is the phenomenon of mitochondrial angiopathy, and not thrombosis. …”
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Rational design of lipid nanoparticles for enabling gene therapies by Cedric A. Brimacombe, Jayesh A. Kulkarni, Miffy H.Y. Cheng, Kevin An, Dominik Witzigmann, Pieter R. Cullis

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A meta-analysis of MHC diversity in Pan troglodytes verus by Christelle Vangenot, Alicia Sanchez‑Mazas

“…The DR locus of catarrhines may display allelic polymorphism, configuration polymorphism and gene-related transcription levels (Doxiadis et al., DR haplotype diversity of the cynomolgus macaque as defined by its transcriptome, Immunogenetics, 2012, 64: 31-37). …”
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Mechanisms, Risk Factors, and Management of Acquired Long QT Syndrome: A Comprehensive Review by Eleftherios M. Kallergis, Christos A. Goudis, Emmanuel N. Simantirakis, George E. Kochiadakis, Panos E. Vardas

“…Long QT syndrome is characterized by prolongation of the corrected QT (QTc) interval on the surface electrocardiogram and is associated with precipitation of torsade de pointes (TdP), a polymorphic ventricular tachycardia that may cause sudden death. …”
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Research progress and prospects on resource utilization of coal gangue for soil remediation in China by Chengyong LIU, Wenzhe GU, Feng CUI, Yun ZHANG, Yanbin YANG, Fengqi QIU, Chaofeng YUAN, Haixing CHENG, Ming LI

“…Looking ahead, efforts should focus on addressing these technological barriers, with particular emphasis on integrated applications, low-cost modifications, cross-regional collaboration, and dynamic monitoring of restoration outcomes. …”
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Minimally invasive differential diagnosis of melanocytic intraocular neoplasms by A. Yu. Tsygankov, S. V. Saakyan, E. B. Myakoshina, A. M. Burdennyi, V. I. Loginov

“…Purpose: to analyze the mutation frequency of the GNAQ/GNA11 gene in circulating tumor DNA and genotypes of the polymorphic marker C3435T of the ABCB1 gene in a large sample of patients with intraocular melanocytic neoplasms (IMN).Material and methods. …”
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Evaluation and genome-wide association study of saline–alkali tolerance in high-latitude rice resource populations by Rongsheng Wang, Rongsheng Wang, Tan Lv, Jingpeng Li, Juntao Ma, Juntao Ma, Yongli Wang, Yongli Wang, Lingwei Deng, Lingwei Deng, Wan Li, Jun Zhang, Jun Zhang, Kun Li, Kun Li, Wei Zhang, Wei Zhang, Fengchen Mu, Fengchen Mu, Guomin Zhang, Guomin Zhang

“…Gene annotation was used to further screen the polymorphic sites in the associated regions, identifying 17 and 48 genes with 593 variants, including 56 polymorphic sites located in exons.DiscussionThis study provided candidate gene loci for the fine mapping of saline–alkali tolerance genes and offered excellent resistant rice resources for the molecular improvement of varieties.…”
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Purifying selection in deeply conserved human enhancers is more consistent than in coding sequences. by Dilrini R De Silva, Richard Nichols, Greg Elgar

“…Comparison of polymorphism at synonymous and non-synonymous sites in protein-coding DNA can provide evidence for selective constraint. …”
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Calorimetric Monitoring of the Sub-T_g Crystal Growth in Molecular Glasses: The Case of Amorphous Nifedipine by Roman Svoboda

“…In particular, the study was focused on the diffusionless glass-crystal (GC) growth mode occurring below the glass transition temperature (T_g). …”
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Genetic diversity and verification of plant material compliance of Cocoa (Theobroma cacao L.) in the Barombi-Kang Regional variety trial. by Nto Marie Claire Eyango, Olivier Sounigo, Olivier Fouet, Honoré Tekeu, François Pierre Djocgoué, Mousseni Ives Bruno Efombagn, Claire Lanaud

“…Cocoa (Theobroma cacao L.) is a pivotal agricultural commodity in Cameroon, which ranks as one of the top five global cocoa producers. This study focused on evaluating the genetic diversity and verifying the plant material compliance of cocoa genotypes in the Barombi-Kang Regional variety trial, employing 12 highly polymorphic SSR markers. …”
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Enhanced Iteroparity Is a Correlated Response to Direct Selection on Blood Feeding in a Mosquito by Rudyard J. Borowczak, Mary A. Wood, William E. Bradshaw, Peter A. Armbruster, Christina M. Holzapfel

“…ABSTRACT Herein, we determine life‐history consequences of selection on blood feeding in a polymorphic population of the pitcher‐plant mosquito, Wyeomyia smithii Coq. …”
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Addressing Conservation Needs: Genetic Diversity and Population Ecology of the Endemic Tree Spondias tuberosa Arruda by Raiane Pereira de Sales, Luan Cavalcanti da Silva, Abidã Gênesis da Silva Neves, Cristiane Gouvêa Fajardo, Luciana Gomes Pinheiro, Fábio de Almeida Vieira

“…Ten molecular markers were selected, generating 103 highly polymorphic loci (99.03%) with an average informative content of 0.45. …”
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GRHPR gene variations in Iraqi patients infected with calcium oxalate kidney stones by Duha Abed Almuhssen Muzahim Alzubaidy, Luma Hassan Alwan Al Obaidy

“…       The alterations in glyoxylate reductase and hydroxy-pyruvate reductase concentrations in the sera and the genetic alterations associated with calcium oxalate kidney stones in Iraqi patients were not studied previously so this study aimed to focus on these points. This study included 80 subjects; they were 50 patients with calcium oxalate stones compared to 30 apparently healthy controls. …”
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