Genomic selection in forest trees comes to life: unraveling its potential in an advanced four-generation Eucalyptus grandis population by Damián Duarte, Esteban J. Jurcic, Esteban J. Jurcic, Joaquín Dutour, Pamela V. Villalba, Carmelo Centurión, Dario Grattapaglia, Eduardo P. Cappa, Eduardo P. Cappa

“…Traditional assessments of the potential of GS in forest trees have typically focused on model performance using cross-validation within the same generation but evaluating effectively realized predictive ability (RPA) across generations is crucial. …”
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Distribution patterns of HLA-A^*, B^*, DRB1^* allele groups among persons who underwent COVID-19 by L. N. Bubnova, I. E. Pavlova, A. S. Berkos, M. A. Terentyeva, T. V. Glazanova, L. V. Erokhina, E. V. Belyaeva, A. V. Chechetkin, N. S. Bashketova, I. G. Chkhindzheria, M. А. Kozhemyakina, D. V. Azarov, R. N. Kuznetsova, Areg A. Totolyan

“…Further evaluation of the HLA gene polymorphism will allow to understand the predetermined immunogenetic basis for susceptibility, as well as clinical severity of COVID-19.…”
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An In-Depth Characterization of SARS-CoV-2 Omicron Lineages and Clinical Presentation in Adult Population Distinguished by Immune Status by Greta Marchegiani, Luca Carioti, Luigi Coppola, Marco Iannetta, Leonardo Alborghetti, Vincenzo Malagnino, Livia Benedetti, Maria Mercedes Santoro, Massimo Andreoni, Loredana Sarmati, Claudia Alteri, Francesca Ceccherini-Silberstein, Maria Concetta Bellocchi

“…This retrospective study analyzed SARS-CoV-2 Omicron variability since its emergence, focusing on immunocompromised (IPs) and non-immunocompromised adult people (NIPs). …”
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Deep analysis of the major histocompatibility complex genetic associations using covariate analysis and haploblocks unravels new mechanisms for the molecular etiology of Elite Cont... by Myriam Rahmouni, Sigrid Le Clerc, Jean-Louis Spadoni, Taoufik Labib, Maxime Tison, Raissa Medina-Santos, Armand Bensussan, Ryad Tamouza, Jean-François Deleuze, Jean-François Zagury

“…Abstract Introduction We have reanalyzed the genomic data from the International Collaboration for the Genomics of HIV (ICGH), focusing on HIV-1 Elite Controllers (EC). Methods A genome-wide association study (GWAS) was performed, comparing 543 HIV-1 EC individuals with 3,272 uninfected controls (CTR) of European ancestry. 8 million single nucleotide polymorphisms (SNPs) and HLA class I and class II gene alleles were imputed to compare EC and CTR. …”
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Genomic insights into the population structure, antimicrobial resistance, and virulence of Brachyspira hyodysenteriae from diverse geographical regions by Maria Hakimi, Fangshu Ye, Anugrah Saxena, Xiao Hu, Huigang Shen, Paarthiphan Elankumaran, Chloe C. Stinman, Nubia Macedo, Orhan Sahin, Eric R. Burrough, Ganwu Li

“…Phylogenomic analysis based on core-genome single nucleotide polymorphisms (SNPs) revealed nine lineages, with L7 (72 isolates, 28.69%), L9 (67 isolates, 26.69%), and L2 (53 isolates, 21.12%) predominating. …”
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