Persistence of SARS-CoV-2-IgG antibody durability in convalescent COVID-19 patients 6 months after the natural infection by Qiaoli Hua, Peng Zhang, Shengle Qin, Bing Feng, Bin Xiao, Guangjuan Zheng, Taoyu Ye, Danwen Zheng, Danwen Zheng, Jiayi Mo, Yuntao Liu, Yuntao Liu, Yun Cai, Xiaohua Xu, Xiaohua Xu, Ji Hu, Banghan Ding, Banghan Ding, Yingrui Li, Yingrui Li, Yingrui Li, Yingrui Li, Jianwen Guo, Jun Wang, Jun Wang, Jun Wang, Hongzhi Cao, Hongzhi Cao, Hongzhi Cao, Zhongde Zhang, Zhongde Zhang, Zhongde Zhang

“…The cohort, comprising 572 COVID-19 patients from Wuhan, China, had no exposure to COVID-19 vaccines, variants, or antiviral treatments, enabling a focused analysis of the virus’s direct impact.ResultsWe found that the rate of RBD-IgG seropositivity 6 months after infection remained high (94.58%). …”
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Uncovering Genetic Variation in Systemic Lupus Erythematosus Risk Variants in Indigenous Peruvians by Cristina M. Lanata, Richard F. Oppong, Mary K. Horton, Victor Borda, Manuel F. Ugarte‐Gil, Joanne Nititham, Eduardo Tarazona‐Santos, Timothy D. O'Connor, Heinner Guio, Lindsey A. Criswell

“…The genetic basis for this is uncertain, and there is a significant lack of genetic research focused on Amerindian ancestry populations. This study aims to compare the frequencies of SLE risk variants and polygenic risk scores between Indigenous Peruvians and global populations with diverse ancestral backgrounds. …”
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<i>In Silico</i> Analysis and Transcriptional Profiling of A Putative Metalloprotease ADAMTSL as A Potential Tick Antigen against <i>Rhipicephalus microplus</i> by Cesar Onoshi Sedano-Juarez, Ninnet Gómez-Romero, Miguel Ángel Alonso-Díaz, América Ivette Barrera-Molina, David Emanuel Reyes-Guerrero, Rodolfo Lagunes-Quintanilla

“…Nevertheless, the efficacy of existing vaccines has been limited by polymorphisms in target antigens among strains from different geographical regions. …”
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Evaluation of common type 2 diabetes risk variants in a South Asian population of Sri Lankan descent. by Neelam Hassanali, N Maneka G De Silva, Neil Robertson, N William Rayner, Amy Barrett, Amanda J Bennett, Christopher J Groves, David R Matthews, Prasad Katulanda, Timothy M Frayling, Mark I McCarthy

“…<h4>Introduction</h4>Most studies seeking common variant associations with type 2 diabetes (T2D) have focused on individuals of European ancestry. These discoveries need to be evaluated in other major ancestral groups, to understand ethnic differences in predisposition, and establish whether these contribute to variation in T2D prevalence and presentation. …”
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Monitoring of chronic wasting disease (CWD) (IV) by EFSA Panel on Biological Hazards (BIOHAZ), Konstantinos Koutsoumanis, Ana Allende, Avelino Alvarez‐Ordoñez, Declan Bolton, Sara Bover‐Cid, Marianne Chemaly, Robert Davies, Alessandra De Cesare, Lieve Herman, Friederike Hilbert, Roland Lindqvist, Maarten Nauta, Luisa Peixe, Panagiotis Skandamis, Elisabetta Suffredini, Michael W Miller, Atle Mysterud, Maria Nöremark, Marion Simmons, Michael A Tranulis, Gabriele Vaccari, Hildegunn Viljugrein, Angel Ortiz‐Pelaez, Giuseppe Ru

“…Additional surveillance may include ad hoc surveys for four different objectives, specific to countries with/without cases, focusing on parallel testing of obex and lymph nodes from adult cervids in high‐risk target groups, sustained over time, using sampling units and a data‐driven design prevalence. …”
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Genetic and non-genetic influences during pregnancy on infant global and site specific DNA methylation: role for folate gene variants and vitamin B12. by Jill A McKay, Alexandra Groom, Catherine Potter, Lisa J Coneyworth, Dianne Ford, John C Mathers, Caroline L Relton

“…Given its central role in provision of methyl groups for DNA methylation, this study focuses on aspects of folate metabolism. Global (LUMA) and gene specific (IGF2, ZNT5, IGFBP3) DNA methylation were quantified in 430 infants by Pyrosequencing®. …”
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Indigenous Knowledge on Edible Wild Yams (Kumbu) in the Mount Cameroon Region: Towards Domestication for Enhanced Food Security by Frederick Tilili Moleye, Mercy Dione Abwe Ngone, Solange Dzekewong Ndzeshala Takwi, Jean-Pierre Mvodo, Christopher Ngosong

“…Growing food insecurity can in part be attributed to a lack of diversity in arable crops, with most African countries now focused on the production of a few “green revolution crops”. …”
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Evaluating award-winning doctoral theses to reveal PhD research landscape: A case study of the Faculty of Medicine, University of Belgrade by Petar Milovanovic, Ranka Stankovic, Vukan Ivanovic, Ana Petrovic, Vladimir Nikolic, Katarina Milutinovic, Marija Jeremic, Lazar Davidovic, Nebojsa Lalic, Tatjana Pekmezovic

“…Background: Doctoral programmes are an important pillar of medical education, and although many universities award the best theses, the criteria for selection of awardees and the topics of their doctoral theses are seldom analysed.Objectives: To analyse the landscape of doctoral research through assessing the temporal trends in the criteria related to recognising the best theses.Methods: A total of 55 award-winning doctoral theses, from those submitted to the Faculty of Medicine, University of Belgrade, over 7 years (2016&amp;ndash;2022), were examined, focusing on the number of awardees, publications based on the theses, research subfields, and keywords.Results: The awardees comprised 36 women (65%) and 19 men (35%). …”
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Maternal exacerbating and protective factors that shape the prevalence and severity of child attention-deficit hyperactivity disorder: a narrative review by Corinne Thorsheim, Sana Khan, Ye Lu, Robert P. Kauffman

“…This narrative review examines the interplay between genetic and epigenetic factors, focusing on specific single nucleotide polymorphisms, polygenic risk scores for ADHD and comorbidities, mitochondrial DNA haplotypes, and X-linked inheritance. …”
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Paternal genetic variants and risk of obstructive heart defects: A parent-of-origin approach. by Jenil Patel, Emine Bircan, Xinyu Tang, Mohammed Orloff, Charlotte A Hobbs, Marilyn L Browne, Lorenzo D Botto, Richard H Finnell, Mary M Jenkins, Andrew Olshan, Paul A Romitti, Gary M Shaw, Martha M Werler, Jingyun Li, Wendy N Nembhard, National Birth Defects Prevention Study

“…Previous research on risk factors for obstructive heart defects (OHDs) focused on maternal and infant genetic variants, prenatal environmental exposures, and their potential interaction effects. …”
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Searching for genes determining the APR phenotype in rye by Joanna Szewińska, Mateusz Matuszkiewicz, Monika Rakoczy-Trojanowska, Magdalena Święcicka, Marianna Krysińska, Wojciech Wakuliński

“…However, our findings are a good starting point for further research, and, as in the case of the ScLr_ABC25 gene - they can be the basis for creating a molecular resistance breeding program focused on selecting forms characterized by APR to LR.…”
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Bioinformatics pipeline to guide late‐onset Alzheimer's disease (LOAD) post‐GWAS studies: Prioritizing transcription regulatory variants within LOAD‐associated regions by Michael W. Lutz, Ornit Chiba‐Falek

“…The current study extends this work by focusing on single nucleotide polymorphisms (SNPs) within these LOAD enhancers and their impact on altering transcription factor (TF) binding. …”
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Breeding for Heat Tolerant Aromatic Rice Varieties and Identification of Novel QTL Regions Associated with Heat Tolerance During Reproductive Phase by QTL-Seq by Surangkana Chimthai, Sulaiman Cheabu, Wanchana Aesomnuk, Siriphat Ruengphayak, Siwaret Arikit, Apichart Vanavichit, Chanate Malumpong

“…Therefore, our objective was to develop heat-tolerant aromatic rice varieties using the pedigree method, focusing on selecting for seed-setting ability under extremely high temperatures along with the use of single nucleotide polymorphism/insertion and deletion (SNP/InDel) markers to improve aromatic properties and grain quality. …”
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Effect of probiotics on mother-to-neonate vertical transmission of group B streptococci: A prospective open-label randomized study by Yuriha Kasai, Mitsutaka Komatsu, Yudai Toyama, Saki Nakano, Ken Hisata, Mie Yamada, Toshiaki Shimizu

“…Recently, attention has been focused on the efficacy of probiotics during the perinatal period. …”
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Comprehensive structural and functional analyses of RAD50 nsSNPs: from prediction to impact assessment by Samina Malik, Mirza Jawad Ul Hasnain, Mirza Jawad Ul Hasnain, Gul Zaib, Haleema Saadia, Arif Malik, Ayesha Zahid

“…This study aims to investigate the functional impact of non-synonymous single-nucleotide polymorphisms (nsSNPs) in RAD50 (a breast cancer-associated gene) and focuses on their consequences on protein structure and interaction within the MRN complex.MethodsA total of 1,806 nsSNPs were retrieved and subjected to variant analysis using a set of computational tools and ConSurf. …”
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Contribution of genetics to hematopoietic stem cell mobilization: a genome-wide association study of 564 healthy donors mobilized with granulocyte colony-stimulating factor by Miriam Stenzinger, Susanne Beck, Iordanis Ourailidis, Anna-Lena Volckmar, Nagarajan Paramasivam, Aysel Ahadova, Aitzkoa Lopez de Lapuente Portilla, Phuong La Yen, Bjorn Nilsson, Justo Lorenzo Bermejo, Halvard Bonig, Jan Budczies

“…None of the association between about 5 million variants and the primary outcome investigated (CD34+ cell frequency in peripheral blood) reached genome-wide significance. Focused analysis of 11 variants previously shown to be associated with basal CD34+ cell levels confirmed an association of CXCR4-rs11688530 (A>G) and ARHGAP45-rs36084354 (A>G) with higher CD34+ frequency in G-CSF mobilized healthy donors showing an explained variance of 1.07% (p=0.004) and 0.86% (p=0.01), respectively. …”
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M. caprae in northern Italy: a comprehensive analysis through whole-genome sequencing on the genetic variability in bovine herds by Cristina Bertasio, Valentina Carta, Giovanni Parisio, Mariagrazia Zanoni, Marco Tamba, Laura Mazzera, Erika Scaltriti, Maria Lodovica Pacciarini, Giovanni Loris Alborali, Daniel Polzer, Annette Nigsch, Romana Steinparzer, Maria Beatrice Boniotti

“…Genomes of 34 Italian strains, with a known and traditionally typed genotype, isolated between 2001 and 2022 from 21 bovine farms, with 12 isolates from Austria, were analyzed focusing on single nucleotide polymorphisms (SNP) to derive evolutionary relationships, pairing with the tracing of infections, suggested by the epidemiological contacts. …”
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Estimation of newborn risk for child or adolescent obesity: lessons from longitudinal birth cohorts. by Anita Morandi, David Meyre, Stéphane Lobbens, Ken Kleinman, Marika Kaakinen, Sheryl L Rifas-Shiman, Vincent Vatin, Stefan Gaget, Anneli Pouta, Anna-Liisa Hartikainen, Jaana Laitinen, Aimo Ruokonen, Shikta Das, Anokhi Ali Khan, Paul Elliott, Claudio Maffeis, Matthew W Gillman, Marjo-Riitta Järvelin, Philippe Froguel

“…We aimed to build clinically useful equations estimating the risk of later obesity in newborns, as a first step towards focused early prevention against the global obesity epidemic.…”
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Independent introductions and nosocomial transmission of Candida auris in Saudi Arabia ─ a genomic epidemiological study of an outbreak from a hospital in Riyadh by Qingtian Guan, Faisal Alasmari, Chang Li, Sara Mfarrej, Mahmoud Mukahal, Stefan T. Arold, Talal S. AlMutairi, Arnab Pain

“…Our study analyzed 23 C. auris isolates from these patients, utilizing whole genome sequencing, single-nucleotide polymorphism (SNP) analysis, phylogenetic analysis, and transmission network construction. …”
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Pathogenic variants identification in primary congenital glaucoma patients using whole exome sequencing by Shahzad Ahmad, Muhammad Saleem Gandapur, Musharraf Jelani, Anees Muhammad, Ihtisham Ul Haq, Yousaf Jamal Mahsood, Sajjad Ahmad, Wadi B. Alonazi, Nousheen Bibi, Muhammad Tahir Sarwar, Taj Ali Khan

“…A prioritization strategy was employed to identify variants in known PCG-related genes, primarily focusing on CYP1B1. Sanger sequencing was carried out to validate candidate variants and perform segregation studies in affected individuals, siblings, parents, and controls. …”
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