Showing 341 - 360 results of 465 for search 'polymorphic focus', query time: 0.09s Refine Results
  1. 341

    Impact of CYP3A4 functional variability on ziprasidone metabolism by Qi Zhou, Qi Zhou, Yameng Wu, Zhize Ye, Zheyan Zhang, Kai Zheng, Jianchang Qian, Zhongxiang Xiao, Yang Lu

    Published 2025-04-01
    “…This study explored the functional variability of CYP3A4 in ziprasidone metabolism, focusing on drug interactions and genetic polymorphisms.MethodsThe metabolic inhibition and kinetic properties of ziprasidone were evaluated through in vitro experiments utilizing rat liver microsomes (RLM), human liver microsomes (HLM), and CYP3A4 baculosomes. …”
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  2. 342

    Epidemic Process Manifestations and Leading Factors of Transmission of The Pathogenes of the Enterovirus Infection Basic Clinical Forms by V. I. Sergevnin, M. A. Tryasolobova

    Published 2019-01-01
    “…In conditions of analytical «case-control»  method the epidemiological survey of 350 epidemiological focuses of SM and 142 focuses of HA and 61 focuses of GE were conducted.  …”
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    Article
  3. 343

    Using next-generation sequencing approach for discovery and characterization of plant molecular markers by Bahman Panahi, Hossein Mohammadzadeh Jalaly, Rasmieh Hamid

    Published 2024-12-01
    “…Next generation sequencing (NGS) has transformed genomics by providing low-cost, high-throughput technologies for the identification of markers in plants. This review focuses on the latest applications, advances and opportunities of NGS in the discovery and characterization of MM in plants. …”
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    Article
  4. 344

    Morphological Analysis of White Cement Clinker Minerals: Discussion on the Crystallization-Related Defects by Mohamed Benmohamed, Rabah Alouani, Amel Jmayai, Abdesslem Ben Haj Amara, Hafsia Ben Rhaiem

    Published 2016-01-01
    “…The results of a study which focused on the identification of white clinker minerals and defects detected in these noncomplying clinkers such as fluctuation of the amount of the main phases (alite (C3S) and belite (C2S)), excess of the free lime, occurrence of C3S polymorphs, and occurrence of moderately-crystallized structures are presented in this paper.…”
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  5. 345

    Micro RNA research in cattle, pig, sheep, and chicken by Neža POGOREVC, Minja ZORC, Tanja KUNEJ

    Published 2015-12-01
    “…Most miRNA research studies are focused on their functioning in muscle, adipose tissues, gonads, fetal development and immune system. …”
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    Article
  6. 346

    Mouse Nkrp1-Clr gene cluster sequence and expression analyses reveal conservation of tissue-specific MHC-independent immunosurveillance. by Qiang Zhang, Mir Munir A Rahim, David S J Allan, Megan M Tu, Simon Belanger, Elias Abou-Samra, Jaehun Ma, Harman S Sekhon, Todd Fairhead, Haggag S Zein, James R Carlyle, Stephen K Anderson, Andrew P Makrigiannis

    Published 2012-01-01
    “…Nkrp1 evolutionary rate. Focused allelic polymorphisms were found within the Nkrp1b/d (Klrb1b), Nkrp1c (Klrb1c), and Clr-c (Clec2f) genes, suggestive of possible immune selection. …”
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    Article
  7. 347

    The interictal transcriptomic map of migraine without aura by Peter Petschner, Sahel Kumar, Duc A. Nguyen, Dora Torok, Zsofia Gal, Daniel Baksa, Kinga Gecse, Gyongyi Kokonyei, Hiroshi Mamitsuka, Gabriella Juhasz

    Published 2025-05-01
    “…Logistic regression of leading genes’ and vitamin A pathway-related polymorphisms identified 11 significant polymorphisms in LRP1. …”
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    Article
  8. 348

    Association of the SNP in akirin 2 Gene With Growth and Carcass Traits in Zavot Cattle by Osman Tufan Ertan, Yunus Arzik, Fadime Daldaban, Korhan Arslan, Bilal Akyuz

    Published 2025-03-01
    “….*188G>A SNP in the 3′‐UTR region of the akirin 2 gene and growth traits in Zavot cattle, focusing on the gene's role in muscle development. …”
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    Article
  9. 349

    CD2AP at the junction of nephropathy and Alzheimer’s disease by Milene Vandal, Mohsen Janmaleki, Isabel Rea, Colin Gunn, Sotaro Hirai, Jeff Biernaskie, Justin Chun, Grant Gordon, Andrey Shaw, Amir Sanati-Nezhad, Gerald Pfeffer, Frederic Calon, Minh Dang Nguyen

    Published 2025-06-01
    “…Abstract Polymorphisms in the gene encoding CD2-associated protein (CD2AP) are associated with an increased risk for developing Alzheimer’s disease (AD). …”
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    Article
  10. 350

    Common Variant in Glycoprotein Ia Increases Long‐Term Adverse Events Risk After Coronary Artery Bypass Graft Surgery by Hanning Liu, Zhengxi Xu, Haiyong Gu, Wenke Li, Wen Chen, Cheng Sun, Kun Zhao, Xiao Teng, Heng Zhang, Lixin Jiang, Shengshou Hu, Zhou Zhou, Zhe Zheng

    Published 2016-12-01
    “…Methods and Results We genotyped GPIA rs1126643 polymorphism of 1592 patients who underwent CABG and followed up for a median period of 72.8 months. …”
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  11. 351
  12. 352

    Artificial intelligence in variant calling: a review by Omar Abdelwahab, Omar Abdelwahab, Omar Abdelwahab, Omar Abdelwahab, Davoud Torkamaneh, Davoud Torkamaneh, Davoud Torkamaneh, Davoud Torkamaneh

    Published 2025-04-01
    “…Variant calling involves the detection of genetic variants such as single nucleotide polymorphisms (SNPs), insertions/deletions (InDels), and structural variants from high-throughput sequencing data. …”
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  13. 353

    Molecular evolution of a pervasive natural amino-acid substitution in Drosophila cryptochrome. by Mirko Pegoraro, Shumaila Noreen, Supriya Bhutani, Avgi Tsolou, Ralf Schmid, Charalambos P Kyriacou, Eran Tauber

    Published 2014-01-01
    “…The SNP frequency spectra and the excessive linkage disequilibrium in this locus suggested that this variation is maintained by natural selection. We focused on a non-conservative SNP involving a leucine-histidine replacement (L232H) and found that this polymorphism is common, with both alleles at intermediate frequencies across 27 populations surveyed in Europe, irrespective of latitude. …”
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  14. 354

    Deoxyribonucleic Acid Extraction Using Iron Oxide Nanoparticle-based Method in Forensic Investigations by Imran Khan, Gaurav Kaushik

    Published 2025-04-01
    “…This review explores the integration of surface-modified iron oxide nanoparticles in forensic DNA extraction, focusing on their intrinsic properties that are critical to their role in DNA isolation. …”
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  15. 355

    Elucidating effects of environmental exposure using human‐induced pluripotent stem cell disease modeling by Mark Chandy, Detlef Obal, Joseph C Wu

    Published 2022-10-01
    “…To date, most studies have focused on the potential for iPSCs for regenerative medicine, drug discovery, and disease modeling. …”
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  16. 356

    Identification of Candida species Isolated From Vulvovaginal Candidiasis Patients by Chromgen agar and PCR-RFLP Method by Baghdad Science Journal

    Published 2016-06-01
    “…This study focuses on diagnosis of Candida species causing Vulvovaginal Candidiasis using phenotype and genotype analyzing methods, and frequencies of candida species also using Vulvovaginal Candidiasis patients. 130 samples (100 from patients and 30 from non infected women) were collected and cultured on biological media. …”
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  17. 357

    Impact Assessment of Mercury Accumulation and Biochemical and Molecular Response of Mentha arvensis: A Potential Hyperaccumulator Plant by R. Manikandan, S. V. Sahi, P. Venkatachalam

    Published 2015-01-01
    “…The present study was focused on examining the effect of Hg oxidative stress induced physiochemical and genetic changes in M. arvensis seedlings. …”
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  18. 358

    Historical and ongoing hybridisation in Southern South American grassland species by Giovanna C. Giudicelli, Pedro H. Pezzi, Sebastián Guzmán-Rodriguez, Caroline Turchetto, Aureliano Bombarely, Loreta B. Freitas

    Published 2024-11-01
    “…Throughout the search for new environments, previously allopatric lineages can come into secondary contact and eventually hybridise if reproductive isolation is incomplete. Here, we focused on two taxa representing the natural herbaceous component of southern South American lowland grasslands. …”
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  19. 359

    Borophene: A 2D wonder shaping the future of nanotechnology and materials science by Raghvendra Kumar Mishra, Jayati Sarkar, Kartikey Verma, Iva Chianella, Saurav Goel, Hamed Yazdani Nezhad

    Published 2025-04-01
    “…Since then, research efforts have focused on controlling the synthesis of semiconducting borophene polymorphs and exploring their novel physical characteristics. …”
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    Article
  20. 360

    Ankylosing Spondylitis: From Cells to Genes by José Francisco Zambrano-Zaragoza, Juan Manuel Agraz-Cibrian, Christian González-Reyes, Ma. de Jesús Durán-Avelar, Norberto Vibanco-Pérez

    Published 2013-01-01
    “…In this review, we analyze the features of HLA-B27 and the suggested mechanisms of its involvement in AS while also focusing on the characterization of the immune response and the identification of genes associated with AS.…”
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