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341
Impact of CYP3A4 functional variability on ziprasidone metabolism
Published 2025-04-01“…This study explored the functional variability of CYP3A4 in ziprasidone metabolism, focusing on drug interactions and genetic polymorphisms.MethodsThe metabolic inhibition and kinetic properties of ziprasidone were evaluated through in vitro experiments utilizing rat liver microsomes (RLM), human liver microsomes (HLM), and CYP3A4 baculosomes. …”
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342
Epidemic Process Manifestations and Leading Factors of Transmission of The Pathogenes of the Enterovirus Infection Basic Clinical Forms
Published 2019-01-01“…In conditions of analytical «case-control» method the epidemiological survey of 350 epidemiological focuses of SM and 142 focuses of HA and 61 focuses of GE were conducted. …”
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343
Using next-generation sequencing approach for discovery and characterization of plant molecular markers
Published 2024-12-01“…Next generation sequencing (NGS) has transformed genomics by providing low-cost, high-throughput technologies for the identification of markers in plants. This review focuses on the latest applications, advances and opportunities of NGS in the discovery and characterization of MM in plants. …”
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344
Morphological Analysis of White Cement Clinker Minerals: Discussion on the Crystallization-Related Defects
Published 2016-01-01“…The results of a study which focused on the identification of white clinker minerals and defects detected in these noncomplying clinkers such as fluctuation of the amount of the main phases (alite (C3S) and belite (C2S)), excess of the free lime, occurrence of C3S polymorphs, and occurrence of moderately-crystallized structures are presented in this paper.…”
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345
Micro RNA research in cattle, pig, sheep, and chicken
Published 2015-12-01“…Most miRNA research studies are focused on their functioning in muscle, adipose tissues, gonads, fetal development and immune system. …”
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346
Mouse Nkrp1-Clr gene cluster sequence and expression analyses reveal conservation of tissue-specific MHC-independent immunosurveillance.
Published 2012-01-01“…Nkrp1 evolutionary rate. Focused allelic polymorphisms were found within the Nkrp1b/d (Klrb1b), Nkrp1c (Klrb1c), and Clr-c (Clec2f) genes, suggestive of possible immune selection. …”
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347
The interictal transcriptomic map of migraine without aura
Published 2025-05-01“…Logistic regression of leading genes’ and vitamin A pathway-related polymorphisms identified 11 significant polymorphisms in LRP1. …”
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348
Association of the SNP in akirin 2 Gene With Growth and Carcass Traits in Zavot Cattle
Published 2025-03-01“….*188G>A SNP in the 3′‐UTR region of the akirin 2 gene and growth traits in Zavot cattle, focusing on the gene's role in muscle development. …”
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349
CD2AP at the junction of nephropathy and Alzheimer’s disease
Published 2025-06-01“…Abstract Polymorphisms in the gene encoding CD2-associated protein (CD2AP) are associated with an increased risk for developing Alzheimer’s disease (AD). …”
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350
Common Variant in Glycoprotein Ia Increases Long‐Term Adverse Events Risk After Coronary Artery Bypass Graft Surgery
Published 2016-12-01“…Methods and Results We genotyped GPIA rs1126643 polymorphism of 1592 patients who underwent CABG and followed up for a median period of 72.8 months. …”
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351
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352
Artificial intelligence in variant calling: a review
Published 2025-04-01“…Variant calling involves the detection of genetic variants such as single nucleotide polymorphisms (SNPs), insertions/deletions (InDels), and structural variants from high-throughput sequencing data. …”
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353
Molecular evolution of a pervasive natural amino-acid substitution in Drosophila cryptochrome.
Published 2014-01-01“…The SNP frequency spectra and the excessive linkage disequilibrium in this locus suggested that this variation is maintained by natural selection. We focused on a non-conservative SNP involving a leucine-histidine replacement (L232H) and found that this polymorphism is common, with both alleles at intermediate frequencies across 27 populations surveyed in Europe, irrespective of latitude. …”
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354
Deoxyribonucleic Acid Extraction Using Iron Oxide Nanoparticle-based Method in Forensic Investigations
Published 2025-04-01“…This review explores the integration of surface-modified iron oxide nanoparticles in forensic DNA extraction, focusing on their intrinsic properties that are critical to their role in DNA isolation. …”
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355
Elucidating effects of environmental exposure using human‐induced pluripotent stem cell disease modeling
Published 2022-10-01“…To date, most studies have focused on the potential for iPSCs for regenerative medicine, drug discovery, and disease modeling. …”
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356
Identification of Candida species Isolated From Vulvovaginal Candidiasis Patients by Chromgen agar and PCR-RFLP Method
Published 2016-06-01“…This study focuses on diagnosis of Candida species causing Vulvovaginal Candidiasis using phenotype and genotype analyzing methods, and frequencies of candida species also using Vulvovaginal Candidiasis patients. 130 samples (100 from patients and 30 from non infected women) were collected and cultured on biological media. …”
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357
Impact Assessment of Mercury Accumulation and Biochemical and Molecular Response of Mentha arvensis: A Potential Hyperaccumulator Plant
Published 2015-01-01“…The present study was focused on examining the effect of Hg oxidative stress induced physiochemical and genetic changes in M. arvensis seedlings. …”
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358
Historical and ongoing hybridisation in Southern South American grassland species
Published 2024-11-01“…Throughout the search for new environments, previously allopatric lineages can come into secondary contact and eventually hybridise if reproductive isolation is incomplete. Here, we focused on two taxa representing the natural herbaceous component of southern South American lowland grasslands. …”
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359
Borophene: A 2D wonder shaping the future of nanotechnology and materials science
Published 2025-04-01“…Since then, research efforts have focused on controlling the synthesis of semiconducting borophene polymorphs and exploring their novel physical characteristics. …”
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360
Ankylosing Spondylitis: From Cells to Genes
Published 2013-01-01“…In this review, we analyze the features of HLA-B27 and the suggested mechanisms of its involvement in AS while also focusing on the characterization of the immune response and the identification of genes associated with AS.…”
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