Realizing high-speed target tracking by using multi-rate feedforward predictive control for the acquisition, tracking, and pointing system by Hang Li, Gaoliang Peng, Xiaobiao Shan, Mingyuan Zhao, Wei Zhang, Jinghan Wang, Feng Cheng

“…The acquisition, tracking, and pointing (ATP) system is widely used in target tracking, counter-UAV operations, and other related fields. …”
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Recent loss of the Dim2 DNA methyltransferase decreases mutation rate in repeats and changes evolutionary trajectory in a fungal pathogen. by Mareike Möller, Michael Habig, Cécile Lorrain, Alice Feurtey, Janine Haueisen, Wagner C Fagundes, Alireza Alizadeh, Michael Freitag, Eva H Stukenbrock

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Functional analysis of CYP4B1 enzymes from apes and humans uncovers evolutionary hot spots for adaptations of the catalytical function. by Saskia Hüsken, Annika Röder, Johannes Ptok, Anne E Meyer, Mats Georg, Yannick Schwarz, Christian Roos, Kerstin Mätz-Rensing, Michael C Hutter, Doreen M Floss, Allan E Rettie, Marco Girhard, Helmut Hanenberg, Constanze Wiek

“…However, due to a single amino acid change (p.P427S) within the evolutionary conserved meander region no catalytic activity of the native human CYP4B1 has been identified so far. To identify at which point in human evolution the loss of CYP4B1 activity had occurred, we evaluated the activities of CYP4B1 orthologs from 14 primate genera against 4-ipomeanol and perilla ketone in human liver cells. …”
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Thermal tipping points in mediterranean mussel adhesion: molecular mechanisms and mechanical consequences of heatwave on byssus production in Mytilus galloprovincialis by Antonina De Marco, Vito Antonio Baldassarro, Corinne Quadalti, Valentina Burato, Laura Calzà, Luciana Giardino, Devis Montroni, Giuseppe Falini, Gabriela Graziani, Nicolas Greggio, Francesco Dondi, Maria Giulia Ferrari, Pier Paolo Gatta, Luca Parma, Alessio Bonaldo

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Can we profit from a loss and still expect substantial gains? Grammatical metaphors as discourse builders and translational choices by Goran Milić, Dubravka Vidaković Erdeljić

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Preventing muscle loss through early mobilization in non-critically ill older adults admitted to surgical intensive care units by Onuma Chaiwat, Thanadol Wachiramatee, Benjaporn Sathitkarnmanee, Suchera Rattanamung, Piyapat Dajpratham, Napat Thikom, Chayanan Thanakiattiwibun

“…We evaluated whether an early mobilization protocol reduces loss of muscle strength and mass compared with usual care in postoperative surgical intensive care unit (SICU) patients. …”
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Cochlear and Bone Conduction Implants in Asymmetric Hearing Loss and Single-Sided Deafness: Effects on Localization, Speech in Noise, and Quality of Life by Oana Astefanei, Cristian Martu, Sebastian Cozma, Luminita Radulescu

“…Background: Single-sided deafness (SSD) and asymmetric hearing loss (AHL) impair spatial hearing and speech perception, often reducing quality of life. …”
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Loss of the Aspergillus fumigatus spindle assembly checkpoint components, SldA or SldB, generates triazole heteroresistant conidial populations by Ashley V. Nywening, Harrison I. Thorn, Jinhong Xie, Adela Martin-Vicente, Xabier Guruceaga, Wenbo Ge, John G. Gibbons, Jarrod R. Fortwendel

“…In this study, we show that loss of the previously uncharacterized A. fumigatus spindle assembly checkpoint (SAC) components, SldA or SldB, resulted in a heteroresistance phenotype to multiple mold active medical triazoles and to compounds inhibiting ergosterol biosynthesis at points upstream of the triazole target, Cyp51A. …”
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Functional literacy of students as a benchmark of modern education by N. A. Aksenova, N. L. Moskovskaya

“…A parallel is drawn between the concept of literacy in the context of the generally accepted concept of acquired human skills, such as reading, writing, arithmetic, as well as from the point of view of successful functioning of society as a whole and the individual's personal achievements by increasing the level of knowledge and potential in particular. …”
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EDT-Net: A Lightweight Tunnel Water Leakage Detection Network Based on LiDAR Point Clouds Intensity Images by Zhenyu Liu, Xianjun Gao, Yuanwei Yang, Lei Xu, Shaoning Wang, Ningsheng Chen, Zhiwei Wang, Yuan Kou

“…Moreover, we developed a dynamic threshold adaptive loss function that automatically adjusts the loss function based on leakage detection performance to enhance the model's ability to detect challenging targets. …”
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Optimization of a multi-environmental detection model for tomato growth point buds based on multi-strategy improved YOLOv8 by Jiang Liu, Jingxin Yu, Changfu Zhang, Huankang Cui, Jinpeng Zhao, Wengang Zheng, Fan Xu, Xiaoming Wei

“…Three key innovations address YOLOv8’s limitations: (1) an SE attention module boosts feature representation in cluttered environments, (2) GhostConv replaces standard convolution to reduce computational load by 19% while preserving feature discrimination, and (3) a scale-adaptive WIoU_v2 loss function optimizes gradient allocation for variable-quality data. …”
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TRANSFORM-HF Trial: Choice of loop diuretic in acute heart failure does not matter! by Akshyaya Pradhan, Arvind Jaiswal, Monika Bhandari

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Titanium dioxide-grafted polyacrylamide nanocomposites ameliorate the rheology and high-pressure high-temperature fluid loss of water-based drilling fluids by Fardin Talebi Sarokolai, Yousef Shiri

“…Under low-pressure low-temperature (LPLT) conditions, the modified fluids presented a 3-fold increase in yield point and a 30 % reduction in fluid loss volume, whereas the filter-cake thickness decreased by two-thirds. …”
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Disrupted care during the COVID-19 state of emergency and productivity loss attributed to presenteeism in workers: a nationwide cross-sectional study by Yoshihisa Fujino, Kanami Tsuno, Ai Hori, Tomohiro Ishimaru, Makoto Okawara, Yoshino Yasuda

“…We performed multiple logistic regression analysis on data from 14 545 participants to investigate the associations among variables related to disrupted care, health status and the Work Functioning Impairment Scale, with a cut-off of 21 points.Results Participants who experienced exacerbation of underlying disease (adjusted OR (aOR) 2.84; 95% CI 2.28 to 3.53) or any type of disrupted care were more likely to show low productivity at work. …”
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Analysis of the Integrated Signal Design for Near-Space Communication, Navigation, and TT&C Based on K/Ka Frequency Bands by Lvyang Ye, Shaojun Cao, Zhifei Gu, Deng Pan, Binhu Chen, Xuqian Wu, Kun Shen, Yangdong Yan

“…In terms of modulation technology, the constant envelope signal shows an advantage in spectral efficiency; the new integrated signal obtained by integrating communication, navigation, and TT&C signals into a single K/Ka frequency point has excellent characteristics in the simulation of power spectral density (PSD) and autocorrelation function (ACF), verifying the feasibility of the scheme. …”
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A Dynamic Reactive Power Optimization Algorithm for Regional Power Grid Based on Decoupling Interior Point Method and Mixed Integer Programming Method by Jie ZHANG, Yunyao ZHENG, Shengchun LIU, Yongfei MA, Wei YAN, Hengfeng WANG

“…Therefore, this paper proposes a two-stage dynamic reactive power optimization algorithm based on decoupling interior point method and mixed integer programming. Firstly, the sigmoid function is used to deal with the absolute value constraint to realize the continuity of the original model, and the idea of decoupling interior point method is used to construct the diagonal band edge structure of the KKT modified equation, so as to realize the time block decoupling and efficient solution of the model. …”
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Onset of End-Stage Atrophic Age-Related Macular Degeneration as an End Point—A Delphi Study: Classification of Atrophy Meetings Report 7 by Zhichao Wu, BAppSc(Optom), PhD, Srinivas R. Sadda, MD, Thomas Ach, MD, Barbara A. Blodi, MD, Ferdinando Bottoni, MD, Usha Chakravarthy, MD, PhD, Emily Y. Chew, MD, Christine A. Curcio, PhD, Frederick L. Ferris, III, MD, Monika Fleckenstein, MD, K. Bailey Freund, MD, Juan E. Grunwald, MD, Frank G. Holz, MD, Glenn J. Jaffe, MD, Sandra Liakopoulos, MD, Tock Han Lim, FRCSEd, Jordi M. Monés, MD, PhD, Sergio Pagliarini, MD, FRCOphth, Daniel Pauleikhoff, MD, Maximilian Pfau, MD, Philip J. Rosenfeld, MD, PhD, David Sarraf, MD, Steffen Schmitz-Valckenberg, MD, Richard F. Spaide, MD, Janet R. Sparrow, PhD, Giovanni Staurenghi, MD, Adnan Tufail, MD, Francesco Viola, MD, Robyn H. Guymer, MBBS, PhD

“…Conclusions: There was expert group consensus that the onset of end-stage atrophy is an appropriate clinical end point to evaluate early interventions in AMD, and that such an end point should show evidence of marked functional loss in prior clinical studies. …”
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Intracerebral Transplants and Memory Dysfunction: Circuitry Repair or Functional Level Setting? by Bruno Will, Christian Kelche, Jean-Christophe Cassel

“…Conversely, with the second paradigm, the grafts are supposed to compensate for a local loss of neurons and must be placed homotopically to induce functional effects that are based on the reconstruction of a point-to-point circuitry. …”
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Peptides actively transported across the tympanic membrane: Functional and structural properties. by Arwa Kurabi, Kerry A Beasley, Lisa Chang, James McCann, Kwang Pak, Allen F Ryan

“…This suggests a preferred peptide motif for TM active transport. Functional and structural comparisons revealed unique features of this peptide: These include a central lysine residue, isoelectric point of 0.0 at physiological pH and a hydrophobic C-terminus. …”
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A Three-Parameter S-Shaped Function of Flood Return Period and Damage by Chaochao Li, Xiaotao Cheng, Na Li, Zhongmin Liang, Yanyan Wang, Song Han

“…The function contains three parameters, which are defined as the maximum flood damage A, critical return period Rc, and integrated loss coefficient k. …”
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