Abstract 185: Visual Recovery after Pituitary Apoplexy: Role of Intervention Timing and Treatment Modality by Nolan Brown

“…Conclusion In the present study, timing of surgical intervention for pituitary apoplexy was only found to be predictive of visual function recovery at the 7‐day timepoint, as has been reported by previous studies. …”
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GAN-based image prediction of maize growth across varieties and developmental stages by Xinyi Wang, Shilong Liu, Zhihao Wang, Zedong Geng, Weikun Li, Chengxiu Wu, Yingjie Xiao, Wanneng Yang, Lingfeng Duan

“…Results This article proposed a visualized growth prediction method based on an improved Pix2PixHD network, incorporating spatial attention mechanisms, an improved loss function, and a modified dropout strategy to enhance prediction accuracy and visual fidelity. …”
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Effect of intravenous versus inhaled anesthetics on blood-brain barrier dysfunction and neuroinflammation in elderly patients undergoing major surgery: study protocol of a randomiz... by Wongook Wi, Hyo-Jin Kim, Sira Bang, Oh Joo Kweon, Doyeon Kim, Eun Jung Oh

“…In the inhaled anesthetics group (group G), bolus injection of propofol will be administered for loss of consciousness, and simultaneously sevoflurane will be initiated for the maintenance of anesthesia. …”
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Inflammasome-Mediated Neuroinflammation: A Key Driver in Alzheimer’s Disease Pathogenesis by Julie McGroarty, Shelbi Salinas, Hayden Evans, Bryan Jimenez, Vincent Tran, Samuel Kadavakollu, Arti Vashist, Venkata Atluri

“…Alzheimer’s disease (AD) is a progressive neurodegenerative disorder predominantly affecting the elderly, characterized by memory loss, cognitive decline, and functional impairment. …”
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Structural and dynamic impacts of single-atom disruptions to guide RNA interactions within the recognition lobe of Geobacillus stearothermophilus Cas9 by Helen B Belato, Alexa L Knight, Alexandra M D'Ordine, Chinmai Pindi, Zhiqiang Fan, Jinping Luo, Giulia Palermo, Gerwald Jogl, George P Lisi

“…These data suggest that guide RNA interactions can be tuned at the biophysical level in the absence of major functional losses but also raise questions about the underlying mechanism of GeoCas9, since analogous single-point mutations have significantly impacted on- and off-target DNA editing in mesophilic Streptococcus pyogenes Cas9. …”
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NPT100-18A rescues mitochondrial oxidative stress and neuronal degeneration in human iPSC-based Parkinson’s model by Julian E. Alecu, Veronika Sigutova, Razvan-Marius Brazdis, Sandra Lörentz, Marios Evangelos Bogiongko, Anara Nursaitova, Martin Regensburger, Laurent Roybon, Kerstin M. Galler, Wolfgang Wrasidlo, Beate Winner, Iryna Prots

“…NPT100-18A and structurally similar compounds (such as NPT200-11/UCB0599, currently being assessed in clinical studies) point towards a promising new approach for disease-modification. …”
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Application of a Hybrid Model Based on CEEMDAN and IMSA in Water Quality Prediction by GUO Li-jin, WU Hao-tian

“…For outlier treatment, the study considered that outliers in the data might be caused by sudden pollution events and discontinuous non-point source pollution. Directly removing them could lead to information loss, so outliers were retained. …”
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The Influence of Green Infrastructure on the Acoustic Environment: A Conceptual and Methodological Basis for Quiet Area Assessment in Urban Regions by Bryce T. Lawrence, Damian Heying, Dietwald Gruehn

“…Recent noise action planning in the German Ruhr region indicates that urban expansion is fueling encroachment upon GI and subsequently the loss of quiet areas. A systematic exploration of this loss in Germany is needed. …”
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YOLO-LSM: A Lightweight UAV Target Detection Algorithm Based on Shallow and Multiscale Information Learning by Chenxing Wu, Changlong Cai, Feng Xiao, Jiahao Wang, Yulin Guo, Longhui Ma

“…Different from previous work on medical detection, this study tailors YOLO-LSM for UAV-based small object detection by introducing targeted improvements in feature extraction, detection heads, and loss functions, achieving better adaptation to aerial scenarios.…”
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Designing a Business Model in the Tourism Industry of Iran by Amirhossein Samadian, Saeid Ehdaie, kamyar Raissifar

“…The key resources component describes the most important assets required for the business model to function properly. Key activities describe the most important tasks required for the business model to function properly. …”
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Diagnostics and Treatment of Esophageal Achalasia (Clinical Guidelines of the Russian Gastroenterological Association, Russian Scientific Medical Society of Internal Medicine, Russ... by V. T. Ivashkin, A. S. Trukhmanov, I. V. Maev, O. M. Drapkina, A. I. Martynov, O. A. Storonova, E. A. Godgello, M. P. Korolev, T. L. Lapina, P. V. Pavlov, A. V. Paraskevova, I. A. Tarasova, E. D. Fedorov, A. T. Tskhovrebov, M. P. Shapka, A. L. Shestakov, A. V. Yurasov

“…Aim: to familiarize gastroenterologists, therapists, functional diagnostics and general practitioners (family doctors), radiologists, and endoscopists with modern methods of diagnosis and treatment of achalasia of the cardia.Key points. …”
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LINC01088 prevents ferroptosis in glioblastoma by enhancing SLC7A11 via HLTF/USP7 axis by Yujie Zhou, Zhen Zhao, Cheng Jiang, Chuansheng Nie, Dongdong Xiao, Zhipeng Wu, Hao Yu, Jianglin Zheng, Xuan Wang, Xiaobing Jiang

“…Methods We conducted gain‐ and loss‐of‐function studies to assess the impact of LINC01088 on GBM tumourigenesis and ferroptosis both in vitro and in vivo. …”
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Liposomal ellagic acid enhances the regenerative potential of ADMSC-laden nanofibrous PCL scaffolds in a rat model of spinal cord injury by Arman Abroumand Gholami, Shokoufeh Rahmani, Payam Moharreri, Esmael Amirazodi, Amir Mahdi Molavi, Tahere Mokhtari, Fatemeh Tahmasebi, Amirhossein Rabiei Rad, Hamideh Babaloo

“…Abstract Spinal cord injury (SCI) leads to myelin breakdown and extensive neuronal loss around the injury site due to increased oxidative stress. …”
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Phosphorylated neurofilament heavy chain (pNfH) concentration in cerebrospinal fluid predicts overall disease aggressiveness (D50) in amyotrophic lateral sclerosis by Julia Meyer, Nayana Gaur, Janina von der Gablentz, Bernd Friedrich, Annekathrin Roediger, Annekathrin Roediger, Julian Grosskreutz, Julian Grosskreutz, Julian Grosskreutz, Robert Steinbach

“…These were (a) the D50, depicting a patient’s overall disease aggressiveness, (b) cFL, the calculated functional loss-rate as locally derived parameter of progression speed, and (c) DPR, the disease progression-rate as more commonly used linear approximation of points lost per month in the ALS functional rating scale since symptom onset.ResultsAll analyses of covariance showed a significant main impact of the respective disease progression-speed parameter on pNfH, independent of disease phase, presence of frontotemporal dementia, analyzing laboratory, sex or clinical onset type, while only age revealed borderline additional influence. …”
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Abstract 203: Predicting Outcomes After Mechanical Thrombectomy: Early vs Delayed Neurological Improvement in the SELECT Database by K. Rose Duncan, Deep Pujara, Amrou Sarraj

“…Possible predictors of early vs late neurological improvement were segregated into pre‐procedure (age, NIHSS at baseline, IV thrombolytic therapy, transfer status, occlusion location, ischemic core, ischemic penumbra, hypoperfusion intensity ratio, successful reperfusion, type of anesthesia, time from last known well to puncture, time from puncture to reperfusion) and post‐procedure (NIHSS at 24‐hour follow‐up, ASPECTS on follow‐up imaging, ASPECTS point loss from baseline, infarct volume on follow‐up imaging, infarct growth from baseline ischemic core, neurological worsening, midline shift, hemorrhagic transformation and type). …”
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Abrasion Resistance and Mechanism Analysis of Polyethylene Fiber-reinforced Cementitious Composite by ZI Jinjia, LI Weibin, WANG Jihong, WANG Zhiwen, LIU Yunjun, NONG Qingshun, LI Bixiong

“…In terms of abrasion resistance, the inclusion of PE fibers effectively reduced the mass loss, wear rate, and average abrasion depth of the specimens. …”
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Apple leaf disease severity grading based on deep learning and the DRL-Watershed algorithm by Zhifang Bi, Fumin Ma, Jiaxiong Guan, Jie Wu, Juxia Li, Fuzhong Li, Yanwen Li, Zhanli Liu

“…Then, we combined the Dice Loss and Focal Loss functions to construct an enhanced HRNet based semantic segmentation model for pixel-level segmentation of both apple leaf and diseased regions. …”
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Enhancing Unmanned Aerial Vehicle Object Detection via Tensor Decompositions and Positive–Negative Momentum Optimizers by Ruslan Abdulkadirov, Pavel Lyakhov, Denis Butusov, Nikolay Nagornov, Dmitry Reznikov, Anatoly Bobrov, Diana Kalita

“…The advanced optimization algorithms achieve the global minimum of loss functions, which makes the precision and recall metrics superior to the ones for their known counterparts. …”
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Characteristic analysis and surgical exploration for acetabular roof fractures: Multicenter retrospective cohort study. by Ruipeng Zhang, Yingchao Yin, Wei Chen, Yan Zhuang, Shicai Fan, Chengla Yi, Gang Lyu, Longpo Zheng, Xiaodong Guo, Ming Li, Guangyao Liu, Zhiyong Hou, Yingze Zhang

“…Satisfactory outcomes were obtained in 46 cases (76.67%), and mean Merle d'Aubigné score was 15.53±1.33 points at the final follow-up. Reduction quality and functional outcome showed no statistical difference in three subtypes (P<0.05). …”
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IGSF10 mutations dysregulate gonadotropin‐releasing hormone neuronal migration resulting in delayed puberty by Sasha R Howard, Leonardo Guasti, Gerard Ruiz‐Babot, Alessandra Mancini, Alessia David, Helen L Storr, Lousie A Metherell, Michael JE Sternberg, Claudia P Cabrera, Helen R Warren, Michael R Barnes, Richard Quinton, Nicolas de Roux, Jacques Young, Anne Guiochon‐Mantel, Karoliina Wehkalampi, Valentina André, Yoav Gothilf, Anna Cariboni, Leo Dunkel

“…Our evidence strongly suggests that mutations in IGSF10 cause DP in humans, and points to a common genetic basis for conditions of functional hypogonadotropic hypogonadism (HH). …”
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