Balancing accuracy and convergence rate: a hybrid optimisation algorithm for parameter identification of unmanned marine vehicles by Zheng Li, Caoyang Yu, Yiming Zhong, Yuanju Cao, Xianbo Xiang, Lian Lian

“…In this structure, the loss function incorporates residuals from all degrees of freedom, thus enabling a comprehensive optimisation of the parameters. …”
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Ursolic Acid Regulates Intestinal Microbiota and Inflammatory Cell Infiltration to Prevent Ulcerative Colitis by Qinsong Sheng, Fei Li, Guanping Chen, Jiacheng Li, Jing Li, YiFan Wang, Yingyan Lu, Qun Li, Mingqian Li, Kequn Chai

“…The early prevention effect of UA could effectively delay mouse weight loss and colon length shorten. UA alleviated UC inflammation and lowered serum and colon IL-6 levels. …”
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THE SEQUANCE OF THE DIAGNOSTIC PROCESS DURING THE INVESTIGATION OF THE MASSETER AND TEMPORALIS MUSCLES IN PATIENTS WITH INTACT DENTAL ROWS by Y. I. Semenenko, I. P. Semenenko, V. M. Dvornik, T. V. Polyschuk

“…Therefore, in the department of prosthodontics and implantology we have developed a proprietary guideline and a map of the orthopedic patient examination, which will be held EMG to standardize the approach to the investigation and establishment of a functional state of dentition. Survey map is based on the comprehensive study of the general state of patients, methodology of dental examination status by WHO for Eastern Europe as ORAL status was used partly - EAST for different age groups of the population (average DMF of dentition, CPI, loss of attachment of ligaments tooth, orthopedic status, the need for prosthetics under objective examination of the patient). …”
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Application of indocyanine green–human serum albumin complex in fluorescence image-guided laparoscopic anatomical liver resection: study protocol for a randomized controlled trial... by Qingyun Xie, Fengwei Gao, Xiaoyun Ran, Xin Zhao, Manyu Yang, Kangyi Jiang, Tianyang Mao, Jiayin Yang, Kun Li, Hong Wu

“…The participants will undergo evaluations at specified time points, and data will be collected using an internet-based electronic data capture system. …”
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Evaluation of an implementation package to deliver the COPD CARE service by Michelle A Chui, Jen Birstler, David Goodrich, Edward Portillo, Molly Lehmann, Timothy Hagen, Martha Maurer, Jordyn Kettner, Sonia Bhardwaj, M Shawn McFarland, Natasha Virrueta, Blake Henderson

“…Patients with COPD suffer from persistent chronic cough, sputum production and exacerbations leading to deteriorating lung function, worsening quality of life and loss of independence. …”
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Dynamin-1 is a potential mediator in cancer-related cognitive impairment by Ding Quan Ng, Casey Hudson, Tracy Nguyen, Sukesh Kumar Gupta, Yong Qin Koh, Munjal M. Acharya, Alexandre Chan

“…Dynamin-1 (DNM1) is crucial for synaptic activity, neurotransmission, and associative memory, positioning it as a potential biomarker of cancer-related cognitive impairment (CRCI), a neurological consequence of cancer treatment characterized by memory loss, poor concentration, and impaired executive function. …”
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Exploration of Pathogenesis and Cutting-Edge Treatment Strategies of Sarcopenia: A Narrative Review by Gao Y, Liu D, Xiao Q, Huang S, Li L, Xie B, Zhou L, Qi Y, Liu Y

“…Yin Gao,1,2,* Di Liu,1,2,* Qixian Xiao,1,* Shan Huang,1,2 Li Li,2 Baocheng Xie,3 Limin Zhou,3 Yi Qi,2 Yanzhi Liu1 1Key Laboratory of Traditional Chinese Medicine for the Prevention and Treatment of Infectious Diseases, Institute of Clinical Medicine, Zhanjiang Central Hospital, Guangdong Medical University, Zhanjiang, 524037, People’s Republic of China; 2Marine Medical Research Institute of Zhanjiang, School of Ocean and Tropical Medicine, Guangdong Medical University, Zhanjiang, 524023, People’s Republic of China; 3Department of Pharmacy, The Tenth Affiliated Hospital of Southern Medical University (Dongguan People’s Hospital), Dongguan, 52305, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yanzhi Liu, Email liuyanzhi@gdmu.edu.cn Yi Qi, Email qiyi7272@gdmu.edu.cnAbstract: Sarcopenia a progressive and multifactorial musculoskeletal syndrome characterized by loss of muscle mass and function, poses a significant global health challenge, particularly in aging populations. …”
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YOLO-MECD: Citrus Detection Algorithm Based on YOLOv11 by Yue Liao, Lerong Li, Huiqiang Xiao, Feijian Xu, Bochen Shan, Hua Yin

“…Secondly, we implemented a CSPPC module based on partial convolution to replace the original C3K2 module, effectively reducing both parameter count and computational complexity while maintaining mAP values. At last, the MPDIoU loss function was employed, resulting in improved bounding box detection accuracy and accelerated model convergence. …”
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Perineal stapled prolapse resection in combination with Thiersch operation for relapsed rectal prolapse: a case report by Teppei Kamada, Hironori Ohdaira, Junji Takahashi, Yoshinobu Fuse, Wataru Kai, Keigo Nakashima, Yuichi Nakaseko, Norihiko Suzuki, Masashi Yoshida, Takeo Usui, Yutaka Suzuki

“…The operative time was 24 min, and intraoperative blood loss was 1 mL. The postoperative course was uneventful. …”
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Penerapan Metode Prototyping Pada Aplikasi Sentra Pelayanan Kepolisian Terpadu Berbasis Web by Mardhiah Fadhli, Annisa Marion

“…The purpose of this research is to assist the public in providing clear information and getting lost more easily and to facilitate the management of lost data from the community in order to determine the points where the loss of goods occurred. This system was built using the Protoyping Method, which is a method to get an overview of the system obtained from the user first, then it will be visited by the user so that it can be a reference for system development. …”
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Sodium pump subunit NKAα1 protects against diabetic endothelial dysfunction by inhibiting ferroptosis through the autophagy‐lysosome degradation of ACSL4 by Xue‐Xue Zhu, Jia‐Bao Su, Fang‐Ming Wang, Xiao‐Ying Chai, Guo Chen, An‐Jing Xu, Xin‐Yu Meng, Hong‐Bo Qiu, Qing‐Yi Sun, Yao Wang, Zhuo‐Lin Lv, Yuan Zhang, Yao Liu, Zhi‐Jun Han, Na Li, Hai‐Jian Sun, Qing‐Bo Lu

“…NKAα1 may serve as an attractive candidate for the management of vascular disorders associated with diabetes. Key points NKAα1 downregulation impairs endothelial function in diabetes by promoting oxidative/nitrative stress and ferroptosis. …”
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KRAS signaling in malignant pleural mesothelioma by Antonia Marazioti, Anthi C Krontira, Sabine J Behrend, Georgia A Giotopoulou, Giannoula Ntaliarda, Christophe Blanquart, Hasan Bayram, Marianthi Iliopoulou, Malamati Vreka, Lilith Trassl, Mario A A Pepe, Caroline M Hackl, Laura V Klotz, Stefanie A I Weiss, Ina Koch, Michael Lindner, Rudolph A Hatz, Juergen Behr, Darcy E Wagner, Helen Papadaki, Sophia G Antimisiaris, Didier Jean, Sophie Deshayes, Marc Grégoire, Özgecan Kayalar, Deniz Mortazavi, Şükrü Dilege, Serhan Tanju, Suat Erus, Ömer Yavuz, Pınar Bulutay, Pınar Fırat, Ioannis Psallidas, Magda Spella, Ioanna Giopanou, Ioannis Lilis, Anne‐Sophie Lamort, Georgios T Stathopoulos

“…Abstract Malignant pleural mesothelioma (MPM) arises from mesothelial cells lining the pleural cavity of asbestos‐exposed individuals and rapidly leads to death. MPM harbors loss‐of‐function mutations in BAP1, NF2, CDKN2A, and TP53, but isolated deletion of these genes alone in mice does not cause MPM and mouse models of the disease are sparse. …”
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Diffusion imaging changes in the treated tract following focused ultrasound thalamotomy for tremor by Erin L. Mazerolle, Robyn Warwaruk-Rogers, Paul Romo, Tejas Sankar, Sarah Scott, Conrad P. Rockel, Samuel Pichardo, Davide Martino, Zelma H.T. Kiss, G. Bruce Pike

“…Diffusion changes at one day post-treatment may reflect local, acute effects such as inflammation and edema, as opposed to chronic degenerative processes such as axonal degeneration and myelin loss that would be expected at later time points. …”
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Approach to shoulder instability: a randomized, controlled trial by Julien Caron, MD FRCSC, Kellen Walsh, MD FRCSC, Tinghua Zhang, MSc, Rashed AlAhmed, MBChB MSc FRCSC, Peter B. MacDonald, MD FRCSC, Cristina Bassi, MD, J Whitcomb Pollock, MD FRCSC MSc, Katie McIlquham, BSc, Peter Lapner, MD FRCSC

“…Background: The significant rate of recurrent instability following arthroscopic stabilization surgery points to a need for an evidence-based treatment approach. …”
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Numerical solution of KdV-mKdV equation based on PINN and its improved method(基于PINN及其改进算法求解KdV-mKdV方程) by 栗雪娟(LI Xuejuan), 刘瑜欣(LIU Yuxin)

“…Although it has a high solution accuracy compared with the traditional methods, PINN's accuracy was overly dependent on the number of configuration points and weakness of large gradients. To overcome these defects, an improved PINN algorithm is proposed based on the idea of gradient enhancement, namely gradient-enhanced physics-informed neural network (gPINN) for solving the problem. gPINN algorithm makes up the defect of gradient attenuation by embedding the gradient information of partial differential equation residuals into the loss function. …”
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The Study of Roadside Visual Perception in Internet of Vehicles Based on Improved YOLOv5 and CombineSORT by LI Xiaohui, YANG Jie, XIA Qin

“…To improve the convergence and reduce the complexity of the model, an advanced loss function of super-efficient IOU (SEIOU) and network pruning are applied. …”
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snRNA-seq reveals subcutaneous white adipose tissue remodeling upon return to thermoneutrality after cold stimulation by Yusha Yang, Yusha Yang, Guanyu Zhang, Ting Yi, Ting Yi, Shuran Yang, Shuran Yang, Shuai Wu, Yongqiang Zhang, Li Zhang, Xi Li, Xiuxuan Wu, Xiuxuan Wu, Jun Li, Danfeng Yang

“…However, this remodeling is reversible: upon return to thermoneutrality (rewarming), sWAT whitens and loses its enhanced metabolic functions. Given the limited understanding of the microscopic dynamic changes and underlying mechanisms during this process, we established a temporally dynamic mouse model spanning the entire period from cold stimulation to the return to thermoneutrality, with inguinal sWAT (iWAT) selected as the study subject.MethodsBased on preliminary data demonstrating stabilization in iWAT histology, expression levels of key thermogenic proteins, and the bulk transcriptome, we selected the two-week time point after the return to thermoneutrality for detailed analysis. …”
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Minilaparoscopic Versus Conventional Laparoscopic Hysterectomy: Insights from a Single-Center Retrospective Cohort Study with Legal Considerations by Valentina Billone, Giuseppe Gullo, Eleonora Conti, Silvia Ganduscio, Sofia Burgio, Giovanni Baglio, Gaspare Cucinella, Lina De Paola, Susanna Marinelli

“…The intraoperative blood loss averaged 195.1 mL in LH and 100.3 mL in MLH (<i>p</i> < 0.001). …”
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Profiling of innate and adaptive immune cells during influenza virus infection reveals sex bias in invariant natural killer T (iNKT) cells by Piotr Humeniuk, Aidan Barrett, Hannes Axelsson, Carmen Corciulo, Christina Drevinge, Alicia Del Carpio Pons, Davide Angeletti, Julia M. Scheffler, Ulrika Islander

“…Methods Female and male mice were infected with mouse‐adapted IAV and monitored for weight loss and survival. Immune cell populations and cytokine expression in bronchoalveolar lavage fluid, lung, and mediastinal lymph node were determined at three time points after infection using flow cytometry and ELISA. …”
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Gender difference in cross-sectional area and fat infiltration of thigh muscles in the elderly population on MRI: an AI-based analysis by Sara Bizzozero, Tito Bassani, Luca Maria Sconfienza, Carmelo Messina, Matteo Bonato, Cecilia Inzaghi, Federica Marmondi, Paola Cinque, Giuseppe Banfi, Stefano Borghi

“…Abstract Background Aging alters musculoskeletal structure and function, affecting muscle mass, composition, and strength, increasing the risk of falls and loss of independence in older adults. …”
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