Perceptions and acceptability of co-administered albendazole, ivermectin and azithromycin mass drug administration, among the health workforce and recipient communities in Ethiopia... by Scott McPherson, Dereje Geleta, Getinet Tafese, Temesgen Tafese, Sinkinesh Behaksira, Hiwot Solomon, Birhanu Oljira, Hirpa Miecha, Lalisa Gemechu, Kaleab Debebe, Biruck Kebede, Teshome Gebre, Fikreab Kebede, Fikre Seife, Fentahun Tadesse, Belete Mammo, Abraham Aseffa, Anthony W Solomon, David C W Mabey, Michael Marks, Endalamaw Gadisa

“…The house-to-house distribution method, adopted as a COVID-19 prevention strategy, was by far preferred by all beneficiaries over central-point MDA, and may have led to greater acceptability of co-administration. …”
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Flanking monomer repeats define lower context complexity of sites containing single nucleotide polymorphisms in the human genome by N. S. Safronova, M. P. Ponomarenko, I. I. Abnizova, G. V. Orlova, I. V. Chadaeva, Y. L. Orlov

“…The changes in point mutation frequency were shown previously for microsatellite containing sequences. …”
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Novel FRMD6::PTH chimera in tumorous bone lesion carrying a t(4;11;14;12)(q35;p15;q22;q13) by Ioannis Panagopoulos, Ioannis Panagopoulos, Kristin Andersen, Isabel Lloret, Ludmila Gorunova, Ingvild Lobmaier

“…In this chimera the expression of the entire coding region of PTH is regulated by the ubiquitously expressed FRMD6 gene promoter. …”
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EVALUATION OF MITOCHONDRIAL DNA MUTATIONS IN SIX FAMILIES BY RESEQUENCING ARRAY by Guyem Kolbaşı Demircioğlu, Sezen Güntekin Ergün, Kıvılcım Gücüyener, Ferda Emriye Perçin, Mehmet Ali Ergün

“…Objective: Human mitochondrial DNA is a circular, double stranded molecule which is inherited through maternal lineage. Point mutations in tRNA, rRNA or protein coding genes and structural rearrangements such as partial deletions or duplications can cause mitochondrial disorders. …”
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Limb-Girdle Muscular Dystrophies (LGMD): Clinical features, diagnosis and genetic variability through next generation sequencing by Priyanshu Mathur, Ashmeet Kaur, Urvashi Vijay, Ashok Gupta, Kamlesh Agarwal, Lokesh Agrawal

“…The types of mutations were mostly point mutations (34 % of missense mutations and 66 % of nonsense mutations). …”
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Digital Technology Use among Preschool Children in Ondo State: Types and Extent by Cynthia Onuegbu, Ezeda P. Kalu, Esther Olayinka Akibu, Ujunwa Evelyn, Oluchi Seraphine

“…However, lower agreement was observed regarding the use of language learning apps, coding apps, math apps, and interactive whiteboards. …”
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Research on data management technology of shearer based on protocol matching and data compression by Zhongbin WANG, Dong WEI, Lei SI, Chaoquan LIANG, Chao TAN, Yihui ZHAO

“…Then the matching algorithm of shearer communication protocol is designed, and the adaptive matching and parsing of communication protocol point table of different types of shearer is realized. …”
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Multiplex PCR and Next Generation Sequencing for the Non-Invasive Detection of Bladder Cancer. by Douglas G Ward, Laura Baxter, Naheema S Gordon, Sascha Ott, Richard S Savage, Andrew D Beggs, Jonathan D James, Jennifer Lickiss, Shaun Green, Yvonne Wallis, Wenbin Wei, Nicholas D James, Maurice P Zeegers, K K Cheng, Glenn M Mathews, Prashant Patel, Michael Griffiths, Richard T Bryan

“…<h4>Methods</h4>DNA was extracted from urine cell pellets and PCR used to amplify the regions of the TERT promoter and coding regions of FGFR3, PIK3CA, TP53, HRAS, KDM6A and RXRA which are frequently mutated in bladder cancer. …”
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Contested narratives: a qualitative analysis of abortion testimonies in Louisiana legislature by Martha Silva, Jeni Stolow, Micki Burdick, Amy Mercieca

“…Religious rhetoric permeates testimony both in support and in opposition to abortion exceptions, making a “pro-life” stance the starting point for debate. Lastly, we find evidence of dehumanization of survivors' and others' experience.ConclusionsThe testimonies around HB346 expose deeply polarized discourse that reflects moral, religious, and ethical conflicts, as well as mismatched conversations that are unlikely to persuade opposing sides. …”
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Deregulation mechanisms and therapeutic opportunities of p53-responsive microRNAs in diffuse large B-cell lymphoma by Elena N. Voropaeva, Yuriy L. Orlov, Anastasia B. Loginova, Olga B. Seregina, Vladimir N. Maksimov, Tatiana I. Pospelova

“…MicroRNAs are the small non-coding RNAs, which regulate genes expression at post-transcriptional level. …”
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Vaccine hesitancy among physicians: a qualitative study with general practitioners and paediatricians in Austria and Germany by Ruth Kutalek, Elena Jirovsky-Platter, Silvia Wojczewski, Katja M Leitner, Kathryn Hoffmann

“…Most of the interview partners do not consider themselves antivaccination, but are sceptical towards vaccines and especially point out the side effects. Most do not vaccinate in their practices and some do only occasionally. …”
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Wellness in the invisible workforce: a pilot well-being study in black, indigenous, and people of color (BIPOC) women faculty in the pharmacy and pharmaceutical sciences by Suzanne C. Harris, Matthew Shane Loop, Kaniz Afroz Tanni, Klarissa D. Jackson, Carla Y. White

“…Post-intervention median WBI decreased, and burnout and well-being risk declined (MBI: 24% and 28% point decrease at risk for burnout, WBI: median score 4 to 3 with 20% decreased risk for poor well-being, and median score 3 to 0.5 with a 61% point decrease at risk for poor well-being, for Cohorts 1 and 2, respectively). …”
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Design and Rationale of the Phase 2 Baricitinib Study in Apolipoprotein L1–Mediated Kidney Disease (JUSTICE) by Opeyemi A. Olabisi, Nadine J. Barrett, Anika Lucas, Maurice Smith, Kenisha Bethea, Karen Soldano, Stephanie Croall, Azita Sadeghpour, Hrishikesh Chakraborty, Myles Wolf

“…The primary safety end point will be incidence of clinically significant decreases in hemoglobin of ≥ 1g/dl. …”
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Integrated transcriptomic and regulatory RNA profiling reflects complex pathophysiology and uncovers a conserved gene signature in end stage heart failure by Amit Anand, Julius Punnen, U.M. Nagamalesh, Sabariya Selvam, Madhusudhan Bysani, Ramya Venkatesh, Kriti Nawin, Shilpa Garg, Bagirath Raghuraman, Varun Shetty, Senthil Kumaran, Manoj Dokania, Pradeep Narayan, Ankita Udwadia, Kushan Gunawardhana, David Gordon, Manjunath Ramarao, Lei Zhao, Jyoti Gulia

“…Conclusions: This study reveals molecular changes underlying the pathophysiology as reflected by coding and regulatory non-coding components of transcriptome from South Asian patients and uncovers a conserved gene signature for HF.…”
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Optimized strategy for real-time qPCR detection of Onchocerca volvulus DNA in pooled Simulium sp. blackfly vectors. by Mary Doherty, Jessica R Grant, Nils Pilotte, Sasisekhar Bennuru, Kerstin Fischer, Peter U Fischer, Sara Lustigman, Thomas B Nutman, Kenneth Pfarr, Achim Hoerauf, Thomas R Unnasch, Hassan K Hassan, Samuel Wanji, Patrick J Lammie, Eric Ottesen, Charles Mackenzie, Steven A Williams

“…The qPCR protocol we propose is also simpler, faster, and more cost-effective than the current end-point molecular assays.…”
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Perceptions of family physicians in Istanbul about e-cigarettes as smoking cessation aids: a qualitative study by Melis Selamoglu, Ayse Emel Onal, Bircan Erbas, Selma Karabey, Meryem Merve Oren, Mahmut Talha Ucar, Chris Barton

“…Abstract Background Family physicians (FPs) are the first point of contact for people who smoke who are seeking to quit smoking in Türkiye. …”
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Circ-PRMT5 promotes gastric cancer progression by sponging miR-145 and miR-1304 to upregulate MYC by Wenbo Du, Ding Li, Xiaomin Guo, Ping Li, Xin Li, Shuping Tong, Junhui Tong, Lihua Kuang, Daoming Liang

“…Circular RNAs (circRNAs) are a new type of non-coding RNA and promising biomarkers for diagnosis of multiple diseases such as cancer.Methods Circ-PRMT5 expression was validated in 90 GC patient tissues and 6 different GC cells by qRT-PCR. …”
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Future-proofing quality education using integrated assessment systems by Lucy Tambudzai Chamba, Namatirai Chikusvura

“…Interviews were held up to saturation point with 60 teachers and students purposively selected from schools in ten provinces across the country. …”
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WEGAN: a web-based community ecology platform by Gina P. Sykes, Gina P. Sykes, Louisa Normington, Jenna Poelzer, Shiyang Zhao, Dana Allen, Samuel Stuart, Eponine Oler, Komal Jot, Vasuk Gautam, Xin Zhao, Jianguo Xia, Glen C. Jickling, David S. Wishart, David S. Wishart, David S. Wishart, David S. Wishart

“…WEGAN offers intuitive workflows and generates detailed tables, publication quality figures and a complete (reproducible) R coding history of all inputs, operations and outputs for every user session, together with comprehensive tutorials. …”
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Rate and risk factors for inpatient falls following single-level posterior lumbar fusion: A national registry study by Michael J. Gouzoulis, BS, Sahir S. Jabbouri, MD, Anthony E. Seddio, BS, Jay Moran, MD, Wesley Day, BS, Philip P. Ratnasamy, BS, Jonathan N. Grauer, MD

“…Patients who had an IPF were determined based on administrative coding. Various patient variables were extracted and variables independently associated with IPFs were assessed with multivariate logistic regression. …”
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