Colorectal cancer mutational profiles correlate with defined microbial communities in the tumor microenvironment. by Michael B Burns, Emmanuel Montassier, Juan Abrahante, Sambhawa Priya, David E Niccum, Alexander Khoruts, Timothy K Starr, Dan Knights, Ran Blekhman

“…However, we do not know whether, in addition to baseline host genetics, somatic mutational profiles in CRC tumors interact with the surrounding tumor microbiome, and if so, whether these changes can be used to understand microbe-host interactions with potential functional biological relevance. Here, we characterized the association between CRC microbial communities and tumor mutations using microbiome profiling and whole-exome sequencing in 44 pairs of tumors and matched normal tissues. …”
Get full text

A Fusion Strategy for High-Accuracy Multilayer Soil Moisture Downscaling and Mapping by Xu Zhang, Xin Liu, Xiang Zhang, Aminjon Gulakhmadov, Jiefeng Wu, Xihui Gu, Won-Ho Nam, Panda Rabindra Kumar, Veber Afonso Figueiredo Costa, Mahlatse Kganyago, Berhanu Keno Terfa, Wenying Du, Chao Wang, Peng Wang, Jing Yuan, Nengcheng Chen

“…Soil moisture (SM) is a critical factor influencing plant growth, agricultural yield, ecosystem functions, and water resource management. Existing SM products, such as SMAP, ERA5, and ESA-CCI, provide daily SM data. …”
Get full text

Energy saving in rail transport by Jan Antoš

“…Based on several partial results, emergent computing tool is functional and sufficiently accurate. The simulation program is supposed to be experimentally verified after its finishing. …”
Get full text

On multipoint Ward identities for superconformal line defects by Gabriel Bliard

“…The constraints on multipoint correlators match the known superconformal Ward identities in the case of 4-point functions. …”
Get full text

Polishing inner wall of crossed deep micropores using magnetic microabrasive jet technology by Zezhi WANG, Jie WANG, Xiaogang MA, Fan LI, Xinya FAN, Yan CHEN

“…Due to the ability of the magnetic abrasive micro-jet to achieve focused fixed-point machining, it has significant processing advantages in cross deep micro-hole finishing and deburring. …”
Get full text

Pramipexole in addition to mood stabilisers for treatment-resistant bipolar depression: the PAX-BD randomised double-blind placebo-controlled trial by Hamish McAllister-Williams, Nicola Goudie, Lumbini Azim, Victoria Bartle, Michael Berger, Chrissie Butcher, Thomas Chadwick, Emily Clare, Paul Courtney, Lyndsey Dixon, Nichola Duffelen, Tony Fouweather, William Gann, John Geddes, Sumeet Gupta, Beth Hall, Timea Helter, Paul Hindmarch, Eva-Maria Holstein, Ward Lawrence, Phil Mawson, Iain McKinnon, Adam Milne, Aisling Molloy, Abigail Moore, Richard Morriss, Anisha Nakulan, Judit Simon, Daniel Smith, Bryony Stokes-Crossley, Paul Stokes, Andrew Swain, Zoë Walmsley, Christopher Weetman, Allan H Young, Stuart Watson

“…Secondary: evaluate the impact of pramipexole on mood and anxiety, psychosocial function, cost-effectiveness, and safety and tolerability over 48 weeks. …”
Get full text

Incorporating a dynamic extraocular muscle simulation model into the undergraduate ophthalmic curriculum by Erqian Wang, Qianyi Yu, Haiyan Xu, Shuang Geng, Enhua Shao, Zhikun Yang, Meifen Zhang, Hui Li

“…All students were given 5-point quizzes on the anatomical and functional basics of extraocular muscles before the lecture(Q1), after the lecture(Q2), and after simulator practice/video-review(Q3). …”
Get full text

Evaluation of the Wind-Resistant Performance of Long-Span Cable-Stayed Bridge Using the Monitoring Correlation between the Static Cross Wind and Its Displacement Response by Gaoxin Wang, Youliang Ding, Dongming Feng, Jihong Ye

“…Third, considering that the traditional function cannot match the monitoring correlation very well, some new fitting functions are thoroughly studied to determine the best function for fitting the monitoring correlation. …”
Get full text

Single, double, and triple-hit strategies to establish a long-term premature rabbit model of bronchopulmonary dysplasia by Chiara Catozzi, Francesca Stretti, Enrica Scalera, Matteo Storti, Angelo Modena, Giorgio Aquila, Gino Villetti, Erica Ferrini, Andrea Grandi, Franco Fabio Stellari, Francesca Ravanetti, Luisa Ragionieri, Roberta Ciccimarra, Matteo Zoboli, Christina Brandenberger, Henri Schulte, Xabier Murgia, Maurizio Civelli, Francesca Ricci

“…Preterm birth at the saccular phase itself, even in the absence of other postnatal BPD hits, was associated with lung function deficits, delayed lung development, and cardiovascular abnormalities compared with age-matched term rabbit pups. …”
Get full text

Le « Plan de Rome » de Paul Bigot à l’Université de Caen et son double virtuel : de l’objet patrimonial à l’outil scientifique by Sophie Madeleine, Philippe Fleury

“…In reconstituting the past, scholars are able to test their assumptions from the architectural and topographic viewpoints and test machine functionality. The visitor to the virtual site is able to wander through a full-scale city and enter most of its large public monuments and a few residences The work preliminary to the reconstruction itself involves the analysis of ancient source materials, which is currently being performed by the project team’s members who have recourse to outside experts for help with specific points. …”
Get full text

Thymic characteristics in patients with autoimmune diseases: a multicentre radiological observational studyResearch in context by Haoxiao Chang, Junqiang Yan, Anxin Wang, Ningning Wang, Peng Liu, Yemin Shi, Xin Zhao, Jinqiao Zhu, Yuan Cai, Xue Xia, Yunyi Hao, Shiyi Yin, Jing Wang, Xinli Wang, Lina Sun, Jia Ma, Xiaoyu Huang, Haonan Guan, De-Cai Tian, Kaibin Shi, Ganqin Du, Wenhao Huang, Guoyan Qi, Hao Li, Yongjun Wang, Fu-Dong Shi, Zhang Zhang, Wei-Na Jin

Get full text

Anisotropic flexible stress sensors based on Loofah/CN/MWCNTs by 刘璐, 贾晓丽, 黄书童, 张景龙, 李守宝, 柯燎亮

“…Flexible stress sensors are key components for realizing intelligent perception of robots and autonomous human-machine interaction. In view of the urgent need for high-performance flexible stress sensors with high sensitivity, wide range, and short response time in the field of human-machine interaction, a flexible stress sensor with conductive anisotropy is proposed, which is made of natural porous loofah as the matrix material and carbon nanoparticles/multi-walled carbon nanotubes (CN/MWCNTs) multidimensional composite materials as conductive coatings. …”
Get full text

hu.MAP 2.0: integration of over 15,000 proteomic experiments builds a global compendium of human multiprotein assemblies by Kevin Drew, John B Wallingford, Edward M Marcotte

“…Abstract A general principle of biology is the self‐assembly of proteins into functional complexes. Characterizing their composition is, therefore, required for our understanding of cellular functions. …”
Get full text

Single‐cell RNA‐sequencing and spatial transcriptomic analysis reveal a distinct population of APOE− cells yielding pathological lymph node metastasis in papillary thyroid cancer... by Guohui Xiao, Rongli Xie, Jianhua Gu, Yishu Huang, Min Ding, Dongjie Shen, Jiqi Yan, Jianming Yuan, Qiong Yang, Wen He, Siyu Xiao, Haizhen Chen, Dan Xu, Jian Wu, Jian Fei

“…Methods Thyroid cancer tissue samples were obtained for single‐cell RNA‐sequencing and spatial transcriptomics, aiming to intratumoral and antimetastatic heterogeneity of advanced PTC. The functions of APOE in PTC cell proliferation and invasion were confirmed through in vivo and in vitro assays. …”
Get full text

Properties of the frustrated spin 1/2 kagome material Cu_{3}(HOTP)_{2} by F. L. Pratt, D. López-Alcalá, V. Garcia-Lopez, M. Clemente-León, J. J. Baldoví, E. Coronado

“…The intralayer J value obtained from calculations using density functional theory is shown to match with the experimental value for reasonable values of the Hubbard U parameter. …”
Get full text

A Single Mechanism Can Account for Human Perception of Depth in Mixed Correlation Random Dot Stereograms. by Sid Henriksen, Bruce G Cumming, Jenny C A Read

“…In order to extract retinal disparity from a visual scene, the brain must match corresponding points in the left and right retinae. …”
Get full text

Penerapan Metode Prototyping Pada Aplikasi Sentra Pelayanan Kepolisian Terpadu Berbasis Web by Mardhiah Fadhli, Annisa Marion

“…The result of the user acceptance test (UAT) from the implementation of the program is that 100% functionality in the application is acceptable …”
Get full text

Enzymes from Fishery and Aquaculture Waste: Research Trends in the Era of Artificial Intelligence and Circular Bio-Economy by Zied Khiari

“…The application of emerging technologies (i.e., artificial intelligence and machine learning) in microbial enzyme production is also presented.…”
Get full text

Towards a Sustainable Disruptive Growth Model: Integrating Foresight, Wild Cards and Weak Signals Analysis by Rafael Popper, Yuli Villarroel, Raimund Popper

“… This paper introduces epistemological and methodological innovations for analyzing non-linear dynamics in sustainability systems, such as deforestation tipping points, exponential renewable adoption, and protests driving global reform. …”
Get full text

Fitness & Sports Medicine by Koehler K

“…Athletes and particularly endurance athletes, such as rowers, expend considerably more energy than their sedentary counterparts, which increases their risk of failing to match these elevated requirements through their diet. …”
Get full text