Altered Density of Resting-State Long- and Short-Range Functional Connectivity in Patients with Moderate-to-Severe Obstructive Sleep Apnea by Liu Y, Xin H, Shu Y, Li L, Long T, Zeng L, Huang L, Liu X, Deng Y, Zhu Y, Li H, Peng D

“…Yumeng Liu,1 Huizhen Xin,1 Yongqiang Shu,1,2 Lifeng Li,1 Ting Long,1 Li Zeng,1 Ling Huang,1 Xiang Liu,1 Yingke Deng,1 Yu Zhu,1 Haijun Li,1,2 Dechang Peng1,2 1Department of Radiology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province, People’s Republic of China; 2PET Center, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province, People’s Republic of ChinaCorrespondence: Dechang Peng; Haijun Li, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, No. 17, Yongwai Zheng Street, Donghu District, Nanchang, Jiangxi Province, 330006, People’s Republic of China, Tel +86 79186427565, Email pengdcdoctor@163.com; haijunli1990@163.comPurpose: This study is to evaluate the altered number of functional connection (s) in patients with obstructive sleep apnea (OSA) by functional connectivity density (FCD), to investigate its relationship with cognitive function, and to explore whether these features could be used to distinguish OSA from healthy controls (HCs).Methods: Seventy-six OSA patients and 72 HCs were included in the analysis. …”
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Ferroptosis-related hub genes and immune cell dynamics as diagnostic biomarkers in age-related macular degeneration by Jinquan Chen, Zhao Long, Dandan Shi, Qian Zhang, H. Peng

“…Therefore, it is imperative that we approach the progress of AMD from novel perspectives in order to explore new therapeutic strategies. …”
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The neglected PCK1/glucagon (inter)action in nutrient homeostasis beyond gluconeogenesis: Disease pathogenesis and treatment by Romina Bertinat, Todd Holyoak, Rodrigo Gatica, Nery Jara, Iván González-Chavarría, Francisco Westermeier

“…Given the shift in glucagon research from receptor inhibition to activation, we propose that a similar paradigm shift is needed in the study of hepatic PCK1. Understanding PCK1 expression and activity in the glucagon-dependent hepatic adaptation to fasting might provide new perspectives and therapeutic opportunities for metabolic diseases.…”
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Facilitators and challenges in collaboration between public health units and faith-based organizations to promote COVID-19 vaccine confidence in Ontario by Kadidiatou Kadio, Denessia Blake-Hepburn, Melodie Yunju Song, Anna Karbasi, Elizabeth Estey Noad, Samiya Abdi, Nazia Peer, Shaza A. Fadel, Sara Allin, Anushka Ataullahjan, Erica Di Ruggiero

“…Braun and Clarke’s “experiential” approach was used to explore the realities of PHUs’ contextual experiences and perspectives. Results The results showed that receptivity and openness of PHUs to learn from FBOs, previous experience working with religious communities and FBOs, ongoing relations based on respect of different beliefs and opinions on the vaccines, leveraging the support of trusted faith leaders among communities and communications strategy adapted and sensitive to the needs of the community was facilitators to community involvement in the prevention and control of COVID-19. …”
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Supply chain management and optimization in transportation logistics by Saoussen Krichen

“…These two classes can scan all problem sizes while generating optima and near optimal solution. As potential perspectives, we can study the importance of implementing a decision support system for a right management of transportation logistics within the supply cha…”
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Integrative analysis of signaling and metabolic pathways, immune infiltration patterns, and machine learning-based diagnostic model construction in major depressive disorder by Lei Tang, Liling Wu, Mengqin Dai, Nian Liu, Lu liu

“…Abstract Major depressive disorder (MDD) is a multifactorial disorder involving genetic and environmental factors, with unclear pathogenesis. This study aims to explore the pathogenic pathway of MDD and its relationship with immune responses and to discover its potential targets by bioinformatics methods. …”
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Honey-fried licorice decoction ameliorates atrial fibrillation susceptibility by inhibiting the NOX2–ROS–TGF-β1 pathway by Yu Qin, Yu Qin, Jingyan Wang, Rong Chen, Zhiling Tang, Hao Zhi, Xiang Wu, Xiaodong Chen, Jialei Fu, Xueting Cai, Jianping Shen, Peng Cao, Peng Cao, Qian Zhou, Qian Zhou

“…However, the specific cardioprotective mechanisms of HFLD in treating AF remain unclear. This study aimed to determine the efficacy of HFLD and validate the efficacy and mechanisms of action of HFLD in reducing AF susceptibility.MethodsSerum oxidative stress biomarker levels of healthy controls and patients with paroxysmal AF were detected using enzyme-linked immunosorbent assay kits. …”
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Improving health-promoting workplaces through interdisciplinary approaches. The example of WISEWORK-C, a cluster of five work and health projects within Horizon-Europe by Deborah De Moortel, Michelle C Turner, Ella Arensman, Alex Binh Vinh Duc Nguyen, Víctor Gonzalez

“…Researching compassionate communities from an interdisciplinary perspective: The case of the compassionate communities center of expertise. …”
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HyperCell: A Bio-inspired Design Framework for Real-time Interactive Architectures by Jia-Rey Chang

“…This involves a detailed study/critique of organic architecture, generating organic shapes, performance optimization based digital fabrication techniques and kinetic systems. …”
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Trust in Artificial Intelligence–Based Clinical Decision Support Systems Among Health Care Workers: Systematic Review by Hein Minn Tun, Hanif Abdul Rahman, Lin Naing, Owais Ahmed Malik

“…Studies in non–English languages and those unrelated to health care settings were excluded. …”
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GIS-Based Remote Sensing Image Information Analysis of the South Atlantic Ecological Environment and Diversity of Deep-Sea Microorganism with Antifungal Effects by Jingjing Xu, Peisheng Yan

“…This paper analyses and studies the quality control mechanism of marine environment monitoring data, the construction of marine environment evaluation model, and the automation of evaluation and early warning response based on the application of GIS, with the support of marine environment evaluation and early warning business, to enhance the availability and integrity of marine environment monitoring data, improve the execution efficiency of marine environment evaluation business and early warning response, reduce the risk of marine environment emergencies, and realize the integration and intelligence of marine environment evaluation and early warning, to improve the level of Informa ionization and management of marine environment evaluation business in marine management departments. …”
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Row configuration affects plant growth and grain yield of drip-irrigated maize-soybean strip intercropping system by regulating photosynthetic capacity and grain filling process by Hongtai Kou, Zhenqi Liao, Yiyao Liu, Zhenlin Lai, Zhijun Li, Junliang Fan

“…In conclusion, the M2S4 maize-soybean strip intercropping system can maximize resources utilization and obtain the maximum benefit of maize under film-mulched drip fertigation in the Hexi Region of China. This study deepens our understanding of how row configuration affect crop yields from physiological perspectives, and provides new ideas and methods for optimizing row configuration to increase population yield of drip-irrigated maize-soybean strip intercropping systems.…”
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Molybdenum Can Regulate the Expression of Molybdase Genes, Affect Molybdase Activity and Metabolites, and Promote the Cell Wall Bio-Synthesis of Tobacco Leaves by Yuan Zhao, Yu Zhang, Kai Zhang, Jiashu Tian, Huanyu Teng, Zicheng Xu, Jiayang Xu, Huifang Shao, Wei Jia

“…These results offer important perspectives for further investigations into the role of trace elements.…”
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Self-monitoring blood pressure in pregnancy: evaluation of women’s experiences of the BUMP trials by Alison Chisholm, Katherine L Tucker, Carole Crawford, Marcus Green, Sheila Greenfield, James Hodgkinson, Layla Lavallee, Paul Leeson, Lucy Mackillop, Christine McCourt, Jane Sandall, Hannah Wilson, Lucy C Chappell, Richard J McManus, Lisa Hinton

“…The findings from this study help us understand the role that self-monitoring of blood pressure can play in maternity care pathways. …”
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TRIM21 promotes type I interferon by inhibiting the autophagic degradation of STING via p62/SQSTM1 ubiquitination in systemic lupus erythematosus by Li Chen, Ma Ang, Bai Yu, Liu Zitao, Tian Linghan, Wang Ziyuan, Ma Huaishun, Chen Zhengpu, Gao Zhengheng, Feng Shijie, Fu Ping

“…Maintaining immune homeostasis requires precise regulation of STING activity to prevent hyperactivation. Our study identifies TRIM21 as a novel positive regulator of cGAS-STING signaling in SLE pathogenesis. …”
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Development of a baculovirus-derived chimeric virus-like particles against QX-type avian infectious bronchitis and H9N2 avian influenza by Bingchen Qiao, Qi Meng, Ni Zhao, Zihe Gao, Yusen Tian, Xifeng Hu, Chenfeng Jiang, Xiaofei Song, Jihui Ping

“…Collectively, these results suggest that the VLPs vaccine developed in this study is a promising vaccine candidate for the avian influenza and infectious bronchitis control, and highlight the potential of VLP-based vaccines as a viable alternative to traditional egg-dependent vaccines in the prevention of poultry diseases.…”
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DNMBP-AS1/hsa-miR-30a-5p/PGC1α axis suppresses tumor progression of colorectal cancer by inhibiting PKM2-mediated Warburg effect and enhance anti-PD-1 therapy efficacy by Tianxiao Wang, Wenxin Zhang, Jiafeng Liu, Xiang Mao, Xinhai Wang, Jiyifan Li, Yuxin Huang, Zimei Wu, Haifei Chen, Huanying Shi, Huijie Qi, Lu Chen, Qunyi Li

“…Our results offer novel perspectives on the role of DNMBP-AS1/hsa-miR-30a-5p/PGC1α network in controlling CRC proliferation, metabolism and immune responses. …”
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Plasma club cell secretory protein reflects early lung injury: comprehensive epidemiological evidence by Jiajun Wei, Jinyu Wu, Hongyue Kong, Liuquan Jiang, Yong Wang, Ying Guo, Quan Feng, Jisheng Nie, Yiwei Shi, Xinri Zhang, Xiaomei Kong, Xiao Yu, Gaisheng Liu, Fan Yang, Jun Dong, Jin Yang

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Discriminating Seagrasses from Green Macroalgae in European Intertidal Areas Using High-Resolution Multispectral Drone Imagery by Simon Oiry, Bede Ffinian Rowe Davies, Ana I. Sousa, Philippe Rosa, Maria Laura Zoffoli, Guillaume Brunier, Pierre Gernez, Laurent Barillé

“…Coastal areas support seagrass meadows, which offer crucial ecosystem services, including erosion control and carbon sequestration. However, these areas are increasingly impacted by human activities, leading to habitat fragmentation and seagrass decline. …”
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The multi-sectorial emergency response to a cholera outbreak in Internally Displaced Persons camps in Borno State, Nigeria, 2017 by Chikwe Ihekweazu, Moise Chi Ngwa, Alemu Wondimagegnehu, Ifeanyi Okudo, Collins Owili, Uzoma Ugochukwu, Peter Clement, Isabelle Devaux, Lorenzo Pezzoli, Mohammed Abba Jimme, Peter Winch, David A Sack

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