RNA sequencing reveals dynamic expression of genes related to innate immune responses in canine small intestinal epithelial cells induced by Echinococcus granulosus protoscoleces by Zhengrong Wang, Zhengrong Wang, Na Pu, Na Pu, Na Pu, Wenqing Zhao, Wenqing Zhao, Wenqing Zhao, Xuke Chen, Xuke Chen, Xuke Chen, Yanyan Zhang, Yanyan Zhang, Yan Sun, Yan Sun, Xinwen Bo, Xinwen Bo, Xinwen Bo

“…This included six samples stimulated with PSCs for 12 h (PSC1_12h–PSC3_12h) and 24 h (PSC1_24h–PSC3_24h) and six corresponding control samples (PBS1_12h–PBS3_12h and PBS1_24h–PBS3_24h). …”
Get full text

549 Mental health care for patients with potential decision-making capacity compromise: Challenging Ontario’s mental healthcare legislation by Leslie Shai, Gilbert Sharpe, Edyta Marcon

“…We must also avoid patients having a subjective experience of coercion and must protect their human rights and dignity. Methods/Study Population: Ontario’s legislation governing mental health care will be explored: the Ontario Mental Health, Healthcare Consent, and Substitute Decisions Acts. …”
Get full text

Nano-Boosted Oils: A New Frontline Against Biofilm Resistance by A. Romero-Montero, I. Nuñez-Tapia, L. J. Melgoza-Ramírez, C. Piña-Barba, D. Giraldo-Gomez, G. Leyva-Gómez, M. L. Del Prado-Audelo

“…This has encouraged the scientific community to explore new perspectives of control. Polymeric nanotechnology and the use of natural compounds have been emerging as promising tools for treating antimicrobial resistance and preventing biofilms because the nanosize permits the disruption of biofilms, reducing the dose and decreasing the biomolecules’ limitations such as high volatility and low solubility, enhancing their antimicrobial properties. …”
Get full text

Head rotation and the perception of eyelid height and contour by Daniel B Rootman, Elana Meer, Nicholas J Jackson, Stefania B Diniz, John M Nesemann

“…However, it is not yet clear how this perception sensitivity impacts eyelid symmetry. This study investigates surgeons’ and laypeople’s accuracy and efficiency in perceiving eyelid asymmetry from different spatial perspectives.Methods A prospective psychometric experiment was conducted where oculoplastic surgeons were recruited from the American Society of Ophthalmic Plastic and Reconstructive Surgery and the Brazilian Oculoplastic Surgery Society, and control participants were recruited via crowdsourcing (Amazon’s Mechanical Turk). …”
Get full text

Practice and discussion on maintenance of seawater pump at LNG terminal by Zhengyin WANG, Hongqiang LIU, Junxiao WANG

“…These components are discussed from the perspectives of main purposes, basic procedures, and operational techniques for overhaul and maintenance. …”
Get full text

Healthcare professionals’ views about delivering a rehabilitation programme for individuals living with Atrial Fibrillation: a cross – sectional survey by Munyra Alhotye, Rachael Evans, Andre Ng, Sally J. Singh

“…The existing approach to managing AF predominantly revolves around medication and medical procedures, and no prescription of tailored rehabilitation program (RP) is currently offered for this population. Aims This study aims to gauge the perspectives of healthcare professionals regarding the implementation of a personalised RP for individuals living with AF and to identify the barriers hindering the referral process. …”
Get full text

Dual-Station Integration Design of Shanghai Suburban Railway Demonstration Zone Line and Shanghai Metro Line 17 Xicen Station under Yangtze River Delta Integration Demand by FANG Yingli, ZHANG Yuan, LI Qin, XU Yue, ZHANG Bin, WANG Jinkun

“…And by conducting demonstrations from three perspectives of architecture, structural design, and interior design, the design response strategies to several major and difficult issues are analyzed. …”
Get full text

Occurrence of antibiotics and antibiotic resistance genes at various stages of different aquaculture modes surrounding Tai Lake, China by Congcong Wu, Congcong Wu, Haitao Ye, Mingzhu Xu, Xuan Zhao, Xuejie Zhao, Lina Li, Mingzhi Li, Yanfei Wei, Yuru Li, Baolan Hu, Baolan Hu

Get full text

Probiotics in piglet: from gut health to pathogen defense mechanisms by Zipeng Jiang, Zipeng Jiang, Mingzhi Yang, Weifa Su, Liang Mei, Yuqi Li, Yuguang Guo, Yangyuan Li, Weifan Liang, Bo Yang, Zhiyi Huang, Yizhen Wang

Get full text

ScnR1-Mediated Competitive DNA Binding and Feedback Inhibition Regulate Guvermectin Biosynthesis in <i>Streptomyces caniferus</i> by Haoran Shi, Jiabin Wang, Xuedong Zhang, Na Zhou, Xiangjing Wang, Wensheng Xiang, Shanshan Li, Yanyan Zhang

“…These findings reveal a multi-layered regulatory mechanism wherein LacI-family TRs fine-tune guvermectin biosynthesis through competitive DNA binding and reciprocal feedback control. This study offers new perspectives on the hierarchical control of secondary metabolism in <i>Streptomyces</i> and provides valuable theoretical guidance for the engineering of strains with enhanced natural product production.…”
Get full text

Comprehensive response assessment of water use efficiency to climate change in ecologically fragile karst areas by Baiyu Lu, Hang Yao, Linsen Zhu, Zhili Chen

Get full text

Spectral Fingerprinting of Tencha Processing: Optimising the Detection of Total Free Amino Acid Content in Processing Lines by Hyperspectral Analysis by Qinghai He, Yihang Guo, Xiaoli Li, Yong He, Zhi Lin, Hui Zeng

“…This study employs VNIR-HSI combined with machine learning algorithms to develop a model for visualizing the total free amino acid content in Tencha samples that have undergone different processing steps on the production line. …”
Get full text

Research progress on shale gas productivity evaluation: concepts, methods and future directions by ZHU Suyang, PENG Zhen, DI Yunting, PENG Xiaolong, LIU Dongchen, GUAN Wenjie

“…Early and late production stages exhibit distinct controlling factors, leading to differentiated perspectives across the various evaluation methods. …”
Get full text

Host protein PRPS2 interact with the non-structural protein p17 of Avian Reovirus and promote viral replication by Hu Xiaomiao, Zhao Ruihong, Li Wei, Pan Xiaocheng, Dai Yin, Wu Huimin, Wu Yantao, Zhang Chengcheng

Get full text

A Distributed Detection Method for Quality-related Faults in Complex Non-stationary Industrial Processes by Jie DONG, Daye LI, Yanmei WEI, Kaixiang PENG, Hui YANG

“…The detection performance is evaluated from the perspectives of fault detection rate (FDR) and false alarm rate (FAR). …”
Get full text

Play, Playfulness, and Self-Efficacy: Parental Experiences with Children on the Autism Spectrum by Rosa Román-Oyola, Verónica Figueroa-Feliciano, Yoliannie Torres-Martínez, Jorge Torres-Vélez, Keyshla Encarnación-Pizarro, Samariz Fragoso-Pagán, Luis Torres-Colón

“…The purpose of this phenomenological study was to explore the perspectives of parents with children on the autism spectrum regarding play experiences and self-efficacy during play encounters. …”
Get full text

Insights into the Regulatory Roles of miRNAs in the Salivary Glands of the Soft Ticks <i>Ornithodoros moubata</i> and <i>Ornithodoros erraticus</i> by Ana Laura Cano-Argüelles, Ricardo Pérez-Sánchez, Cristian Gallardo-Escárate, Rocío Vizcaíno-Marín, María González-Sánchez, Ana Oleaga

“…These findings highlight the functional relevance of salivary miRNAs in tick physiology and host interaction, offering new perspectives for the development of innovative tick control strategies.…”
Get full text

Development and Perfection of Marine-Based Insecticide Biofilm for Pea Seed Protection: Experimental and Computational Approaches by Fatouma Mohamed Abdoul-Latif, My Ismail El Mhamdi, Ayoub Ainane, Ali Merito Ali, Khadija Oumaskour, Sanaa Cherroud, Stefano Cacciatore, Tarik Ainane

“…This mechanism highlights the targeting of the olfactory complex as a potential strategy to control insect pests. This research contributes to the understanding of the role of marine-based biofilms for seed protection and opens perspectives for the development of ecological solutions against insect pests, particularly in the field of sustainable agriculture.…”
Get full text

Exploring the heterogeneity of osteosarcoma cell characteristics and metabolic states and their association with clinical prognosis by Sen Qin, YaoFeng Hu, RuCui Deng, Zhe Wang

“…Despite progress in comprehensive treatment approaches, the five-year survival rate remains largely unchanged, highlighting the need to clarify its underlying mechanisms and discover new therapeutic targets.MethodsThis study utilized RNA sequencing data from multiple public databases, encompassing osteosarcoma samples and healthy controls, along with single-cell RNA sequencing data. …”
Get full text

The organizational dimension in rare and complex diseases care management: an application of RarERN Path© methodology in ataxias, dystonia and phenylketonuria by Sara Cannizzo, Vinciane Quoidbach, Leopoldo Trieste, Monika Benson, Antonio Federico, Alessandro Filla, Bernadette Sheehan Gilroy, Paola Giunti, Holm Graeßner, Julie Greenfield, Tobias Hagedorn, Alvaro Hermida, Barry Hunt, Anita MacDonald, Francesca Morgante, Wolfgang Oertel, Gregory Pastores, Martje G. Pauly, Carola Reinhard, Maja Relja, Eileen Treacy, Francjan Van Spronsen, Julie Vallortigara, Giuseppe Turchetti

Get full text