Cost-utility analysis of empagliflozin compared with dapagliflozin in patients with type 2 diabetes in China by Huiyuan Zhang, Jiaojiao Chen, Quan Zhao, Bei Zhang

“…The objective of this study is to evaluate the long-term cost-utility of the addition of empagliflozin (10 mg or 25 mg) versus dapagliflozin (10 mg) in T2DM patients with insufficient control by metformin monotherapy from the perspective of Chinese health care payers.MethodsThe IQVIA CORE diabetes model was used for cost-utility analysis to compare the long-term economics of empagliflozin (10 or 25 mg) versus dapagliflozin (10 mg) respectively. …”
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Interplay between alcohol, smoking and HLA genes in RA aetiology by Anna Karin Hedström, Lars Klareskog, Lars Alfredsson, Ola Hössjer

“…We aimed to determine the influence of alcohol on anticitrullinated protein antibody (ACPA) positive and ACPA-negative RA and investigate potential interactions between alcohol consumption, smoking and the presence of human leucocyte antigen (HLA)-DRB1-shared epitope (SE).Methods A Swedish population-based case–control study with incident cases of RA was used (3353 cases, 2836 matched controls). …”
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The Impact of HbA1C on Postoperative Complications Following Orthopaedic Surgeries to the Foot and Ankle: A Systematic Review by Jacek Parylo MB ChB, BSc (hons), Erika Pond, Paula McQuail MB BCh, BAO, MCh, FRCSI, Basil Budair MBBS, MSc, FRCS (Tr & Orth)

“…Focussed attention should be given to T2DM from a foot and ankle perspective to determine the threshold for safer surgery. …”
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Research Progress and Prospects on Risk Assessment and Early Warning for Embankment Safety in Estuarine and Coastal Areas by ZHU Yong-hui, LI Meng-yu, LUAN Hua-long, QU Geng, YUAN Yuan, WU Wei-wei, GE Jian-zhong, GUO Jun

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Global surge: exploring cryptocurrency adoption with evidence from spatial models by Ivan Sergio, Jan Wedemeier

“…Despite challenges, cryptocurrencies such as Bitcoin are gaining widespread acceptance, particularly in countries with unbanked populations, the lack of bank controls, and inflation. This study investigates the global patterns of cryptocurrency adoption using Generalized Linear Models and Spatial Autoregressive Models. …”
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On the Dynamics and Stability of the Crime and Punishment Game by María J. Quinteros, Marcelo J. Villena

“…We study the dynamics and stability of the economics of crime and punishment game from an evolutionary perspective. …”
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Decoding Pro-Environmental Behaviors in China Through Values and the Theory of Planned Behavior by Lijun Luo, Wonkyung Kim

“…In light of fostering pro-environmental behaviors among the public, this study explores factors driving pro-environmental behaviors. …”
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Application of Concentration-Area fractal modeling and artificial neural network to identify Cu, Zn±Pb geochemical anomalies in Hashtjin area, NW of Iran by Ali Imamalipour, Hamed Ebrahimi, Amir reza Abdollahpur

“…The results obtained from applying the fractal method to the output of the deep autoencoder method indicated a potentially favorable area for the mineralization with approximately 9,047,500 m² In the predictive map obtained in the northeast of the studied area, an area with high mineralization potential is introduced, which is geologically represented by the Upper Jurassic (Lar Formation) and Cretaceous formation controlled by, fault boundaries and in the northeastern part of the Hashtjin. …”
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“It’s Up to Me Whether I Do—Or Don’t—Watch Deepfakes”: Deepfakes and Behavioral Intention by Wanqi Li, Huiying Zhao

“…The rapid spread of disinformation and misinformation created by deepfake poses threats and challenges to society. Most studies have analyzed deepfakes in terms of computer science, but there is now a pressing need to study them from the perspective of social science. …”
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Commentary on “Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open label non-randomized clinical trial” by Gautret et al by Mondher Toumi, Samuel Aballea

“…The study has a number of limitations, including small sample size, lack of comparability between patients in active treatment and control arms, lack of blinding, use of interim analyses without controlling for the risk of type 1 error, use of analysis in the per-protocol population instead of the intention-to-treat population, and inconsistencies between the study protocol and article. …”
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Evidence for the use of a nonsteroidal mineralocorticoid receptor antagonist for the treatment of chronic kidney disease by Mariana Morais David Pliças, Bernardo Marques da Silva, Edgar Avito Fernandes de Almeida

“…Apararenone is being investigated for diabetic kidney disease, with results from a phase two study, limited for only including Japanese patients. …”
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The association between the MIND diet and cognitive health in middle-aged and older adults: A systematic review by Jenny Hiu Wai Tse, Queenie Pui Sze Law, Jenny Tsun Yee Tsang, Lorna Kwai Ping Suen, Stefanos Tyrovolas, Rick Yiu Cho Kwan

“…Secondary analyses of population studies and randomized controlled trials (RCTs) show mixed results on the MIND diet's effectiveness in improving cognitive health. …”
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Seminal plasma metabolomics approach for the diagnosis of unexplained male infertility. by Shanlei Qiao, Wei Wu, Minjian Chen, Qiuqin Tang, Yankai Xia, Wei Jia, Xinru Wang

“…We used a gas chromatography-mass spectrometry (GC-MS) based metabolomics approach to obtain the metabolic profiling of unexplained male infertility (UMI), and identified seminal plasma biomarkers associated with UMI by a two-stage population study. A robust OPLS-DA model based on these identified metabolites was able to distinguish 82% of the UMI patients from health controls with a specificity of 92%. …”
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Canine Distemper Virus in Mexico: A Risk Factor for Wildlife by Juan Macías-González, Rebeca Granado-Gil, Lizbeth Mendoza-González, Cesar Pedroza-Roldán, Rogelio Alonso-Morales, Mauricio Realpe-Quintero

“…Mexico is home to at least two wildlife species that have been reported as carriers of the CDV infection in studies in the USA. Raccoons and Coyotes are distributed in several Mexican states and could play the same reservoir role as for the US. …”
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Measuring community resilience of flash floods using a multilevel interpretive structure model: Quantification and time-varying responses by Ming Zhong, Feng Ling, Weichen Zhong, Qian Zhang

“…Flood-prone communities are characterized by geographical dispersion and confinement. This study carries out a research on disaster resilience and time-varying effects from the perspective of flash flood, and proposes a multidisciplinary integrated approach: (1) A multilevel interpretive structure model of the influencing factors of community resilience based on coupling decision mathematical model was constructed to analyze the differential influencing factors of community resilience; (2) The information diffusion method was used to quantitatively analyze and rank the community resilience of flash flood disasters; (3) Rand Index was used to quantitatively estimate the magnitude of community resilience and analyze the characteristics of its time-varying effect curve. …”
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What were the spatial-temporal distributions of agricultural water resource efficiency in China? by Jianfang Wang, Hongxia Sheng, Hongxia Sheng, Guangming Yang, Guangming Yang, Darong Li, Darong Li, Yizhi Qin, Yizhi Qin, Changchun Zhou, Lijuan Zou

“…Improving the utilization efficiency of agricultural water resources constitutes one of the effective approaches to addressing the current issue of water resource scarcity. This study, from the perspective of water resource pollution severity, integrates the DPSIRM model with the Slacks-Based Measure (SBM) method, thereby constructing a novel DPSIRM-SBM model to measure and analyze the agricultural water resource utilization efficiency across 31 provinces in China. …”
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Influence of Different Water Vapor Sources on the Precipitation Processes on the Qinghai-Xizang （Tibet） Plateau in Summer by Changrui ZHU, Minhong SONG, Shaobo ZHANG, Longtengfei MA

“…Based on the knowledge that the main sources of summer water vapor on the Qinghai-Xizang （Tibet） Plateau are the Arabian Sea， the Bay of Bengal， and the South China Sea， a simulation study of the effects of different water vapor sources on the eastern-type and western-type precipitation on the Qinghai-Xizang （Tibet） Plateau in summer was carried out.Numerical simulations of water vapor content reduction at different water vapor source locations were conducted using conventional observations， NCEP/NCAR global reanalysis data， and the mesoscale numerical model WRF for two intense precipitation processes on the Qinghai-Xizang （Tibet） Plateau from June 28 to July 2， 2016 （eastern type） and from July 19 to 23， 2018 （western type）， by separately integrating the Arabian Sea， Bay of Bengal， and South China Sea By comparing three sets of sensitivity experiment and control experiment， the relative humidity at the Arabian Sea， the Bay of Bengal and the South China Sea was reduced by 70%， 60%， 50%， 40% and 30% from the ground to 100hPa respectively， and the effects of the reduction of water vapor content at different water vapor sources on summer precipitation on the plateau were explored in depth from the perspectives of circulation field， water vapor transport and precipitation changes， and the following main conclusions were obtained： （1） The reduction of water vapor content at three water vapor sources has an effect on The reduction of water vapor over the Bay of Bengal significantly reduced the summer precipitation of the Qinghai-Xizang （Tibet） Plateau by about 10% in 2016 （eastern type） and 2018 （western type） compared with the controlled experiment， while the reduction of water vapor over the South China Sea had minimal effects on the two summer precipitation processes of the Qinghai-Xizang （Tibet） Plateau.Reducing the water vapor over the Arabian Sea plays a catalytic role in the precipitation of the western type of the plateau， increasing the precipitation by about 10% relative to the controlled test； and inhibiting the precipitation of the eastern type of the plateau， making the precipitation decrease by about 5% relative to the controlled test.（2） Changing the water vapor conditions over the Bay of Bengal source has the most obvious effect on the precipitation on the Qinghai-Xizang （Tibet） Plateau.The possible reason is that reducing the water vapor conditions over the Bay of Bengal makes the low value system on the southern side of the plateau weaken， and the southerly wind on the plateau weakens， resulting in weaker water vapor transport， resulting in less precipitation on the plateau.（3） The difference of water vapor revenue and expenditure in the plateau region was not obvious in the control experiment and three sensitivity experiment at the beginning of the simulation， but with the increase of simulation time （after about 48 h）， there were obvious differences in water vapor revenue and expenditure in the Qinghai-Xizang （Tibet） Plateau， and there was an obvious correlation between water vapor revenue and expenditure and daily precipitation.…”
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Well-Being in Psoriasis: Weighting its Components Using Best-worst Scaling Methodology by Esteban Daudén, Isabel Belinchón, Elena Colominas-González, Pablo Coto, Pablo de la Cueva, Fernando Gallardo, Jose Luis Poveda, Esther Ramírez, Sandra Ros, Ricardo Ruíz-Villaverde, Isabel Cabezas, Luis Lizán

“…Abstract Introduction The Inpsight Project, established in 2021, aimed to define the concept of well-being in patients with psoriasis from a holistic perspective. Well-being was defined as a multi-dimensional concept that includes achieving emotional balance, having adequate overall health and control of the disease, enjoying positive social relationships, and being satisfied with disease care. …”
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The long noncoding RNA APR attenuates PPRV infection-induced accumulation of intracellular iron to inhibit membrane lipid peroxidation and viral replication by Bo Wen, Wenchi Chang, Lulu Yang, Daiyue Lv, Lizhen Wang, Lei Wang, Yanzhao Xu, Jianhe Hu, Ke Ding, Qinghong Xue, Xuefeng Qi, Bo Yang, Jingyu Wang

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Masyarakat Madani dan Relevansinya Dengan Pendidikan Islam (Telaah Filosofis) by Hambali Alman Nasution, Trisandi Trisandi

“… This study aims to analyze the concept of civil society and its relevance to Islamic education from a philosophical perspective. …”
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