Unveiling functionality and conducting two-sample mendelian randomization on WGCNA-identified oxidative stress-related hub genes in metabolic dysfunction-associated fatty liver dis... by Qian Zhu, Jiaqi Liu, Wuxuan Mei, Changchun Zeng

“…These findings offer innovative perspectives on the applications of OS-associated genes in individuals afflicted with MAFLD.…”
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Perceptions of Teacher-trainees Towards using YouTube Videos to improve Conceptual Understanding of the Reactivity of Alkali Metals in Natural Sciences at a Rural University in Sou... by Vuyokazi Momoti

“…The focus of the research was to understand the perspectives of teacher candidates regarding the significance of YouTube in enhancing their understanding of laboratory safety and alkali metal reactivity. …”
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Development of a framework on the incorporation of real-world evidence (RWE) into cancer drug funding decisions in Canada: the Canadian Real-world Evidence for Value of Cancer Drug... by Stuart Peacock, Avram Denburg, Petros Pechlivanoglou, Wanrudee Isaranuwatchai, Claire de Oliveira, Yvonne Bombard, Scott Gavura, Jeffrey Hoch, Rebecca E Mercer, Wei Fang Dai, Jaclyn Beca, Mina Tadrous, Carole Chambers, Maureen Trudeau, Craig C Earle, Kelvin Kar-Wing Chan, Winson Y Cheung, Pam Takhar, William K Evans, Caroline Muñoz, Erica Craig, Marc Geirnaert, Tarry Ahuja, Riaz Alvi

“…First, an environmental scan and qualitative study were conducted to understand the current state and key stakeholder perspectives on RWE. Next, five formal working groups (WGs) were established consisting of stakeholders with cancer drug funding expertise including clinicians, patients, methodologists, payers, regulatory decision-makers and data analysts. …”
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Patient-centered outcomes on preparing for and undergoing gender-affirming phalloplasty: a qualitative, descriptive study by Daphna Harel, Asa Radix, Rachel Bluebond-Langner, Tenny R Zhang, Carolyn A Berry, Nnenaya Mmonu, Elijah Castle, Lee Zhao, Clarissa Ospina-Norvell, Mark Fendrick

“…Objective Despite increasing incidence of genital gender-affirming surgery (GGAS), there is no systematic method of evaluating patient perspectives. The objective of this study is to elucidate transgender and non-binary patient perspectives on gender-affirming phalloplasty/metoidioplasty via structured focus groups and determine convergent themes as the first step towards the development of a GGAS patient-reported outcome measure.Design We conducted a systematic qualitative study using a thematic content analysis of four focus groups from April 2021 to April 2022 comprising 8 patients undergoing phalloplasty/metoidioplasty and 10 patients post-phalloplasty/metoidioplasty. …”
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3DSHAPE-AR: PROFIL PENALARAN SPASIAL MATEMATIS MAHASISWA DI POLITEKNIK MELALUI PEMBELAJARAN GEOMETRI BERBASIS AUGMENTED REALITY [3DSHAPE-AR: PROFILE OF STUDENTS' MATHEMATICAL SPATI... by Indah Riezky Pratiwi, Riki Afriansyah, Shidiq Andriyanto, Agnes Erianti, Rima Julianti

“…From the analysis stage, it was concluded that the use of the 3DShape-AR application in geometry learning was able to provide changes in the quality of students' mental rotation, spatial orientation and spatial visualization components. These three components are components that describe the quality of a person's mathematical reasoning skills. …”
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A Bi-Level Capacity Optimization Method for Hybrid Energy Storage Systems Combining the IBWO and MVMD Algorithms by Qiaoqiao Xing, Shidong Li, Da Qiu, Yang Long, Qinyi Liao, Xiangjin Yin, Yunxiang Li, Kai Qian

“…With the swift evolution of renewable energy technologies, the design and optimization of microgrids have emerged as vital components for fostering energy transition and promoting sustainable development. …”
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Aging towards walkable futures: insights from a multidisciplinary workshop held in Barcelona, Spain by Enric Vall-Garcia, Laura Delgado-Ortiz, Lisa Alcock, Laura Coll-Planas, José Augusto García-Navarro, Susanne Iwarsson, Josep Maria Jansà, Carl-Philipp Jansen, Sarah Koch, Simon Schwartz, Merja Rantakokko, Adelaida Sarukhan, Willeke van Staalduinen, Lynn Rochester, Judith Garcia-Aymerich

“…Participants discussed the meaning of walking from different perspectives and its change with age and in the presence of diverse mobility-impairing conditions; the emotional and social components of walking; and the role of the environment in walking. …”
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Carbon Emission Accounting Methods for Key Electric Equipment and Materials in Power Transmission and Transformation Projects by Keyun LI, Ning ZHANG, Le ZHAO, Cheng ZHAO, Jiayu LI, Cheng TANG

“…The research results show that wires, tower materials and transformers are the main components of the total carbon emissions, thus it is essential to focus on carbon emissions of the equipment, and promote the research on carbon reduction in electrical equipment and materials.…”
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Avalanche Multiplication in Two-Dimensional Layered Materials: Principles and Applications by Zhangxinyu Zhou, Mengyang Kang, Yueyue Fang, Piotr Martyniuk, Hailu Wang

“…Furthermore, we highlight representative applications of avalanche devices in logic circuits, optoelectronic components, and neuromorphic computing systems. By synthesizing the principles and applications of the avalanche multiplication effect, this review aims to offer insightful perspectives on future research directions for 2D material-based avalanche devices.…”
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Play, Playfulness, and Self-Efficacy: Parental Experiences with Children on the Autism Spectrum by Rosa Román-Oyola, Verónica Figueroa-Feliciano, Yoliannie Torres-Martínez, Jorge Torres-Vélez, Keyshla Encarnación-Pizarro, Samariz Fragoso-Pagán, Luis Torres-Colón

“…Parental narratives denoted playful experiences reflecting components of Skard and Bundy’s model of playfulness. …”
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Micro-costing analysis from Italian Guidelines for the management of sporadic primary hyperparathyroidism by Ilaria Valentini, Michele Basile, Fabio Vescini, Giorgio Borretta, Iacopo Chiodini, Marco Boniardi, Marina Carotti, Elena Castellano, Cristiana Cipriani, Cristina Eller-Vainicher, Sandro Giannini, Maurizio Iacobone, Antonio Stefano Salcuni, Federica Saponaro, Stefano Spiezia, Annibale Versari, Guido Zavatta, Zuzana Mitrova, Rosella Saulle, Alexia Giovanazzi, Roberto Novizio, Agostino Paoletta, Enrico Papini, Agnese Persichetti, Irene Samperi, Alessandro Scoppola, Pietro Giorgio Calò, Filomena Cetani, Luisella Cianferotti, Sabrina Corbetta, Maria Luisa De Rimini, Alberto Falchetti, Stefano Laureti, Bruno Madeo, Claudio Marcocci, Sandro Mazzaferro, Vittorio Miele, Salvatore Minisola, Andrea Palermo, Jessica Pepe, Alfredo Scillitani, Franco Grimaldi, Renato Cozzi, Roberto Attanasio

“…This study evaluates the economic impact of different PHPT treatment approaches from both the Italian National Health Service and societal perspectives. Methods: A micro-costing approach was used to estimate the costs of surgical and non-surgical treatments. …”
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Improvement of the Anticancer Efficacy of PD‐1/PD‐L1 Blockade: Advances in Molecular Mechanisms and Therapeutic Strategies by Peng Gao, Xiao Li, Zhenyu Duan, Yang Wang, Yinggang Li, Jing Wang, Kui Luo, Jie Chen

“…This article provides a comprehensive overview of PD‐1/PD‐L1 blockade resistance mechanisms from both primary and acquired resistance perspectives, including tumor intrinsic factors, immune microenvironment components, and systemic factors. …”
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A consortium of Hordeum vulgare and gut microbiota against non-alcoholic fatty liver disease via data-driven analysis by Su-Been Lee, Haripriya Gupta, Byeong-Hyun Min, Raja Ganesan, Satya Priya Sharma, Sung-Min Won, Jin-Ju Jeong, Min-Gi Cha, Goo-Hyun Kwon, Min-Kyo Jeong, Ji-Ye Hyun, Jung-A Eom, Hee-Jin Park, Sang-Jun Yoon, Sang Youn Lee, Mi-Ran Choi, Dong Joon Kim, Ki-Kwang Oh, Ki-Tae Suk

“…Holistically, we scrutinized GBSTM to identify key components (GM, signalling pathways, targets, and metabolites) associated with the Apelin signalling pathway. …”
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Epigenetic regulation of histone modifications in glioblastoma: recent advances and therapeutic insights by Li Zhang, Yang Yang, Yanchu Li, Chenyu Wang, Chenbin Bian, Hongbin Wang, Feng Wang

“…Additionally, the review discusses current clinical trials targeting histone modifications in GBM, highlighting successes, limitations, and future perspectives.…”
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Inflammatory Mechanisms Underlying Metabolic Syndrome-associated Osteoarthritis and Potential Treatments by Shiqian Huang, Jiawei Chen, Hao Zhang, Wenjing Wu, Song Xue, Zhaohua Zhu, Changhai Ding

“…Currently, the understanding of MOA remains limited, with a prevailing consensus attributing its etiology to the core components of metabolic syndrome: obesity, hyperglycemia, dyslipidemia, and hypertension. …”
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Transforming biomass into engineered biochar materials for high-performance supercapacitors: Recent advances, challenges, and prospects by Ruibo FAN, Liang CHEN, Beichen XUE, Ao WANG, Yinhai SU, Huiyan ZHANG, Xiangzhou YUAN

“…Finally, detailed assessments from perspectives of environmental benefits and economic feasibilities are proposed as science-based guidelines for industries and policymakers. …”
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An Intelligent Agent-Based Resilient Framework for Marine Vessel Mission Adaptations by Nikos Kougiatsos, Evelien L. Scheffers, Marcel C. van Benten, Dingena L. Schott, Peter de Vos, Rudy R. Negenborn, Vasso Reppa

“…The connection between the system architecture and control design perspectives is enabled using a semantics-based technique. …”
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Resilience-by-Design in 6G Networks: Literature Review and Novel Enabling Concepts by Ladan Khaloopour, Yanpeng Su, Florian Raskob, Tobias Meuser, Roland Bless, Leon Janzen, Kamyar Abedi, Marko Andjelkovic, Hekma Chaari, Pousali Chakraborty, Michael Kreutzer, Matthias Hollick, Thorsten Strufe, Norman Franchi, Vahid Jamali

“…Next, adopting an interdisciplinary approach, we propose to embed these principles across all 6G layers/perspectives including electronics, physical channel, network components and functions, networks, services, and cross-layer and cross-infrastructure considerations and discuss their challenges. …”
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Development and Perfection of Marine-Based Insecticide Biofilm for Pea Seed Protection: Experimental and Computational Approaches by Fatouma Mohamed Abdoul-Latif, My Ismail El Mhamdi, Ayoub Ainane, Ali Merito Ali, Khadija Oumaskour, Sanaa Cherroud, Stefano Cacciatore, Tarik Ainane

“…Eight biofilm formulations were prepared with different concentrations of the components and tested on <i>Sitona lineatus</i> and <i>Bruchus pisorum</i>. …”
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Optimization of a company’s capital structure based on the criterion of minimizing the level of financial risk by Hanna Filatova, Viktoriya Kulyk, Olena Kravchenko

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