Efficacy of sensorimotor training combined with core strength training for low back pain in adult idiopathic scoliosis: a study protocol for a randomized controlled trial by Tongtong Zhang, Xin Li, Xuan Zhou, Nan Chen, Qing Du, Hong Yu, Xiaoqing Zhu, Qimeng Fan, Juping Liang, Zhengquan Chen, Xiangyue Zhou

“…Sessions will be conducted in the hospital, and no home programme will be provided. Adherence and attendance will be monitored and recorded. …”
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Using the Community Perception Tracker (CPT) to inform COVID-19 response in Lebanon and Zimbabwe: a qualitative methods evaluation by Fiona Majorin, Anika Jain, Christine Haddad, Eddington Zinyandu, Ghassan Gharzeddine, Mutsawashe Chitando, Aline Maalouf, Ntandoyenkosi Sithole, Rita Doumit, Raissa Azzalini, Thomas Heath, Janet Seeley, Sian White

“…Most population members also felt the COVID-19 programmes were relevant to their needs and said that non-government organisations were a trusted source of information. …”
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CRISPR‐Based Environmental Biosurveillance Assisted via Artificial Intelligence Design of Guide‐RNAs by Benjamín Durán‐Vinet, Jo‐Ann L. Stanton, Gert‐Jan Jeunen, Ulla vonAmmon, Jackson Treece, Xavier Pochon, Anastasija Zaiko, Neil J. Gemmell

“…SENTINEL presented a robust, streamlined method incorporating the trained neural network, achieving a sensitivity down to 10 attomolar using recombinant DNA and down to ~0.34 copies/μL for eDNA samples with 1 h, costing 3.5 USD per sample. There was a 100% agreement between SENTINEL results and qPCR‐based analysis of the eDNA samples. …”
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Cessation of smoking in people attending UK emergency departments: the COSTED RCT with economic and process evaluation by Ian Pope, Lucy V Clark, Allan Clark, Emma Ward, Pippa Belderson, Susan Stirling, Steve Parrott, Jinshuo Li, Timothy Coats, Linda Bauld, Richard Holland, Sarah Gentry, Sanjay Agrawal, Benjamin M Bloom, Adrian Boyle, Alasdair Gray, M Geraint Morris, Caitlin Notley

“…Secondary outcomes were: self-reported 7-day smoking abstinence, number of quit attempts, number of cigarettes per day, nicotine dependence and incidence of self-reported dry cough or mouth or throat irritation. …”
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Benefits of aldosterone receptor antagonism in chronic kidney disease: the BARACK-D RCT by F D Richard Hobbs, Richard McManus, Clare Taylor, Nicholas Jones, Joy Rahman, Jane Wolstenholme, Louise Jones, Jennifer Hirst, Sam Mort, Ly-Mee Yu

“…The addition of low-dose spironolactone was estimated to have a cost per quality-adjusted life-year gained value above the National Institute for Health and Care Excellence’s threshold of £30,000. …”
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Direct oral penicillin challenge in secondary care with low-risk patients: the SPACE mixed-methods study with cost-effectiveness analysis by Mamidipudi Thirumala Krishna, Yogini H Jani, Iestyn Williams, Ruben Mujica-Mota, Rebecca Bestwick, Michele Siciliano, Robert Michael West, Rashmeet Bhogal, Bee Yean Ng, Kornelija Kildonaviciute, Rachel Pollard, Nicola Jones, Louise Dunsmure, Mairead McErlean, Neil Powell, Chidanand C Hullur, Ariyur Balaji, Jonathan Sandoe, Amena Warner, Ron Daniels, Caroline Thomas, Siraj A Misbah, Louise Savic

“…The EVPI was highest in Oxford, where the value of further research per de-labelled patient varied in the range of £20–25 across clinical settings, whereas in Leeds it varied between £100 per de-labelled patient in haematology-oncology, £6 in the presurgical group and £0 in AMU/IDU while in Birmingham it was £0 in all three patient groups. …”
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Cervical ripening at home or in hospital during induction of labour: the CHOICE prospective cohort study, process evaluation and economic analysis by Mairead Black, Cassandra Yuill, Mairi Harkness, Sayem Ahmed, Linda Williams, Kathleen A Boyd, Maggie Reid, Amar Bhide, Neelam Heera, Jane Huddleston, Neena Modi, John Norrie, Dharmintra Pasupathy, Julia Sanders, Gordon C S Smith, Rosemary Townsend, Helen Cheyne, Christine McCourt, Sarah Stock

“…Economic analysis Incremental cost per neonatal unit admission within 48 hours of birth avoided. …”
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Evaluating the population impact of hepatitis C direct acting antiviral treatment as prevention for people who inject drugs (EPIToPe) – a natural experiment (protocol) by Jeremy Horwood, Andrew Radley, John F Dillon, Peter Vickerman, Rory N Gunson, Mary Ramsay, Chris Metcalfe, William Hollingworth, Hannah Fraser, Helen Harris, Ellen Heinsbroek, Lawrie Elliott, Paul Flowers, Sema Mandal, Matthew Hickman, David Goldberg, Natasha Martin, Emma Hamilton, Daniela De Angelis, Graham Foster, Peter Donnan, Ann Eriksen, Samreen Ijaz, David Liddell, Lewis J Z Beer, Kate Drysdale, Rachel Glass, Lesley Graham, Ross Harris, Vivian Hope, Sarah Karen Inglis, Hamish Innes, Athene Lane, Jade Meadows, Andrew McAuley, Stephanie Migchelsen, Alex Murray, Gareth Myring, Norah E Palmateer, Anne Presanis, Pantelis Samartsidis, Ruth Simmons, Katy Sinka, Gabriele Vojt, Zoe Ward, David Whiteley, Alan Yeung, Sharon J Hutchinson

“…Over 2 years from 2017/2018, at least 500 PWID will be treated in Tayside, which simulation studies project will reduce chronic HCV prevalence among PWID by 62% (from 26% to 10%) and HCV incidence will fall by approximately 2/3 (from 4.2 per 100 person-years (p100py) to 1.4 p100py). Treatment response and re-infection rates will be monitored. …”
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Collagenase injection versus limited fasciectomy surgery to treat Dupuytren’s contracture in adult patients in the UK: DISC, a non-inferiority RCT and economic evaluation by Joseph Dias, Puvan Tharmanathan, Catherine Arundel, Charlie Welch, Qi Wu, Paul Leighton, Maria Armaou, Belen Corbacho, Nick Johnson, Sophie James, John Cooke, Christopher Bainbridge, Michael Craigen, David Warwick, Samantha Brady, Lydia Flett, Judy Jones, Catherine Knowlson, Michelle Watson, Ada Keding, Catherine Hewitt, David Torgerson

“…The collagenase group had more complications (n = 267, 0.82 per participant) than the limited fasciectomy group (n = 177, 0.60 per participant), but limited fasciectomy participants had a greater proportion of ‘moderate’/‘severe’ complications (5% vs. 2%). …”
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A randomised trial to compare the safety, tolerability and efficacy of three drug combinations for intermittent preventive treatment in children. by Kalifa Bojang, Francis Akor, Ousman Bittaye, David Conway, Christian Bottomley, Paul Milligan, Brian Greenwood

“…Sulfadoxine-pyrimethamine (SP) given alone or in combination with other drugs has been used for most IPT programmes. However, SP resistance is increasing in many parts of Africa. …”
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Unravelling climate misinformation: fact-checking of climate disinformation in spanish-speaking podcasts by Mercè Cisneros, Jon X Olano Pozo, Anna Boqué-Ciurana, Caterina Cimolai, Daniel Dermit, Andrea Arnal, Marc Masip, Javier Sigro, Enric Aguilar

“…During COP27, the daily rate of climate mis- and disinformation claims (7.5 per day) was significantly higher than during the regular period (2.9 per day). …”
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Pramipexole in addition to mood stabilisers for treatment-resistant bipolar depression: the PAX-BD randomised double-blind placebo-controlled trial by Hamish McAllister-Williams, Nicola Goudie, Lumbini Azim, Victoria Bartle, Michael Berger, Chrissie Butcher, Thomas Chadwick, Emily Clare, Paul Courtney, Lyndsey Dixon, Nichola Duffelen, Tony Fouweather, William Gann, John Geddes, Sumeet Gupta, Beth Hall, Timea Helter, Paul Hindmarch, Eva-Maria Holstein, Ward Lawrence, Phil Mawson, Iain McKinnon, Adam Milne, Aisling Molloy, Abigail Moore, Richard Morriss, Anisha Nakulan, Judit Simon, Daniel Smith, Bryony Stokes-Crossley, Paul Stokes, Andrew Swain, Zoë Walmsley, Christopher Weetman, Allan H Young, Stuart Watson

“…Exclusion criteria: randomisation stage As per pre-randomisation stage including. Psychotic symptoms over the preceding 4 weeks. …”
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Interpersonal counselling for adolescent depression delivered by youth mental health workers without core professional training: the ICALM feasibility RCT by Jon Wilson, Viktoria Cestaro, Eirini Charami-Roupa, Timothy Clarke, Aoife Dunne, Brioney Gee, Sharon Jarrett, Thando Katangwe-Chigamba, Andrew Laphan, Susie McIvor, Richard Meiser-Stedman, Jamie Murdoch, Thomas Rhodes, Carys Seeley, Lee Shepstone, David Turner, Paul Wilkinson

“…For those who were recruited after suspension (n = 14), the overall rate of recruitment was slower than anticipated: on average, 1.7 per month (18 months) versus a target recruitment rate of five participants per month (12 months). …”
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Universal or Specific? A Modeling-Based Comparison of Broad-Spectrum Influenza Vaccines against Conventional, Strain-Matched Vaccines. by Rahul Subramanian, Andrea L Graham, Bryan T Grenfell, Nimalan Arinaminpathy

“…Influenza vaccination programmes around the world are steadily increasing in their population coverage. …”
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Evaluation of prognostic models to improve prediction of metastasis in patients following potentially curative treatment for primary colorectal cancer: the PROSPECT trial by Vicky Goh, Susan Mallett, Manuel Rodriguez-Justo, Victor Boulter, Rob Glynne-Jones, Saif Khan, Sarah Lessels, Dominic Patel, Davide Prezzi, Stuart Taylor, Steve Halligan

“…Funding This award was funded by the National Institute for Health and Care Research (NIHR) Health Technology Assessment programme (NIHR award ref: 09/22/49) and is published in full in Health Technology Assessment; Vol. 29, No. 8. …”
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Asian Rhino Specialist Group report
/ Rapport du Groupe de Spécialistes du Rhinocéros d'Asie by Bibhab Kumar Talukdar

“… Currently the critically endangered Javan Rhino is only found in Ujung Kulon National Park (NP) in Banten province of west Java, Indonesia. As per annual camera trapping surveys being carried out by the Ujung Kulon NP authorities the current Javan rhino population is estimated to be 72 of which 38 are male and 33 are female. …”
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Improving health outcomes by strengthening public sector capacity in social and behaviour change programming in Nigeria: a qualitative study by Pooja Sripad, Augustine Ankomah, Amanda Kalamar, Adetayo Adetunji, Bright Addo, Dele Abegunde, Nrupa Jani Tulsiani, Foyeke Oyedokun-Adegbabo

“…Nine study participants were engaged per state, bringing the total number of participants to 45. …”
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p53 and TIGAR promote redox control to protect against metabolic dysfunction-associated steatohepatitis by Celine I. Wittke, Eric C. Cheung, Dimitris Athineos, Nicola Clements, Liam Butler, Mark Hughes, Vivienne Morrison, Dale M. Watt, Karen Blyth, Karen H. Vousden, Timothy J. Humpton

“…Background & Aims: TP53 is a potent tumour suppressor that coordinates diverse stress response programmes, ranging from pro-survival activities to cell death. p53 is also engaged during tissue damage and repair, including within the liver. …”
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Better public housing management in Ghana by Samson Aziabah

“…It also builds on knowledge of lesson drawing and the transferability of programmes (see Rose, 2001) from one context to another. …”
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