Microhabitat accessibility determines peptide substrate degradation by soil microbial community by Carlos Arellano-Caicedo, Pelle Ohlsson, Saleh Moradi, Edith C. Hammer

“…We found that in both cases, channels and mazes, decreasing accessibility produced a higher peptide substrate degradation. When we analyzed the degradation within the structures, we found that most of the activity is concentrated in the regions of intermediate accessibility. …”
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KRSA: An R package and R Shiny web application for an end-to-end upstream kinase analysis of kinome array data. by Erica A K DePasquale, Khaled Alganem, Eduard Bentea, Nawshaba Nawreen, Jennifer L McGuire, Tushar Tomar, Faris Naji, Riet Hilhorst, Jaroslaw Meller, Robert E McCullumsmith

“…Peptide array technologies like the PamStation12 from PamGene allow for generating high-throughput, multi-dimensional, and complex functional proteomics data. …”
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Investigating the Antimicrobial Activity of Anuran Toxins by Manuela B. Pucca, Anne Grace A. C. Marques, Ana Flávia M. Pereira, Guilherme Melo-dos-Santos, Felipe A. Cerni, Beatriz C. S. Jacob, Isabela G. Ferreira, Rafael L. Piccolo, Marco A. Sartim, Wuelton M. Monteiro, Isadora S. Oliveira

“…These glands secrete a diverse array of bioactive compounds, including peptides, alkaloids, and other secondary metabolites, shaped by evolutionary pressures. …”
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Development of Antisense Tools to Study Bodo saltans and Its Intracellular Symbiont by Mastaneh Ahrar, Lorna Glenn, Marie Held, Andrew Jackson, Krzysztof Kus, Gregory D. D. Hurst, Ewa Chrostek

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THE INFLUENCE OF Bacillus subtilis PROTEINS DegU, SinR AND SinIR ON BACITRACIN BIOSYNTHESIS IN Bacillus licheniformis by A. GASPARIČ, Tina DULAR, Alenka GROŠEL, G. SLADIČ, I. RADEŽ, Ines MANDIČ MULEC

“…A vast array of natural peptides diverse in their structure that are produced by microorganisms living in different aquatic and terrestrial environments are not gene encoded but are synthetized nonribosomally on peptide synthetases. …”
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The MASP family of Trypanosoma cruzi: changes in gene expression and antigenic profile during the acute phase of experimental infection. by Sara Lopes dos Santos, Leandro Martins Freitas, Francisco Pereira Lobo, Gabriela Flávia Rodrigues-Luiz, Tiago Antônio de Oliveira Mendes, Anny Carolline Silva Oliveira, Luciana Oliveira Andrade, Egler Chiari, Ricardo Tostes Gazzinelli, Santuza Maria Ribeiro Teixeira, Ricardo Toshio Fujiwara, Daniella Castanheira Bartholomeu

“…Additionally, to investigate the MASP antigenic profile, we performed B-cell epitope prediction on MASP proteins and designed a MASP-specific peptide array with 110 putative epitopes, which was screened with sera from acutely infected mice.…”
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Positive charges promote the recognition of proteins by the chaperone SlyD from Escherichia coli. by Daniel Lindemeier, Wenke Graubner, Denise Mehner-Breitfeld, Miroslav Malešević, Thomas Brüser

“…Using peptide arrays to analyze these signal peptide interactions, we found that SlyD interacted only with positively charged peptides, with a preference for arginines over lysines, and large hydrophobic residues enhanced binding. …”
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An integrated approach to the characterization of immune repertoires using AIMS: An Automated Immune Molecule Separator. by Christopher T Boughter, Martin Meier-Schellersheim

“…The adaptive immune system employs an array of receptors designed to respond with high specificity to pathogens or molecular aberrations faced by the host organism. …”
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Pharmacokinomic Profiling Using Patient-Derived Cell Lines Predicts Sensitivity to Imatinib in Dermatofibrosarcoma Protuberans by Rei Noguchi, Takuya Ono, Kazuki Sasaki, Mari Masuda, Akira Kawai, Yuki Yoshimatsu, Tadashi Kondo

“…Four DFSP cell lines that we established were analyzed for tyrosine kinase activities on PamChip, a three-dimensional peptide array, in the presence and absence of imatinib, along with an imatinib-sensitive cell line, GIST-T1, as a positive control. …”
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Conserved LIR-specific interaction of Sigma-1 receptor and GABARAP by Marius Wilhelm Baeken, Maximilian Christ, Daniel Schmitt, Wencke Trein, Heike Nagel, Albrecht Martin Clement, Hagen Körschgen, Christian Behl

“…Biochemically, we uncovered a GABARAP-σ1R interaction depending on this motif via peptide array analysis and confirmed this via immunoprecipitation, co-localization, and proximity ligation assays. …”
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Relationship of cytokine level dynamics with longterm results of early rheumatoid arthritis therapy by V. V. Rybakova, A. S. Avdeeva, D. A. Dibrov, Е. L. Nasonov

“…The majority of patients were women (n=77), middle-aged (58 [49; 66] years), with an early stage of the disease (the duration of the disease is 7 [4–11.5] months), seropositive according to IgM rheumatoid factor and cyclic citrullinated peptide antibodies, who had high (59.7%) or moderate (38.8%) disease activity.The concentration of 27 cytokines in the blood serum was determined with the help of multiplex xMAP technology on the Bio-Plex array system analyzer (BIORAD, USA). …”
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Bioactive Terpenes from Marine Sponges and Their Associated Organisms by Yuan Yuan, Yu Lei, Muwu Xu, Bingxin Zhao, Shihai Xu

“…Marine sponges are prolific producers of a vast array of bioactive compounds, including terpenes, alkaloids, peptides, and numerous secondary metabolites. …”
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Trichosanthes dioica Roxb.: A vegetable with diverse pharmacological properties by Mahia Khandaker, Saleha Akter, Mohammad Zafar Imam

“…In this review, we critically analyzed and presented the scientific studies on T. dioica available in three electronic databases viz. …”
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Unraveling the Toxicity of a Non-Microcystin-Producing Strain (CCIBt3106) of <i>Microcystis aeruginosa</i>: Ecotoxicological Effects on Aquatic Invertebrates by Éryka Costa Almeida, Fernanda Rios Jacinavicius, Rhuana Valdetário Médice, Rafaella Bizo Menezes, Larissa Souza Passos, Dominique Anderson, Jaewon Yoon, Elaine Dias Faria, Camila Manoel Crnkovic, Ana Lúcia Fonseca, Theodore Henry, Ernani Pinto

“…Cyanobacterial blooms are becoming increasingly frequent and intense worldwide, often dominated by <i>Microcystis aeruginosa</i>, a species capable of producing a wide array of bioactive metabolites beyond microcystins. …”
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A customizable multiplex protein microarray for antibody testing and its application for tick-borne and other infectious diseases by Hari Krishnan Krishnamurthy, Vasanth Jayaraman, Karthik Krishna, Tianhao Wang, Kang Bei, Chithra Changalath, Shiny Matilda, Alex J. Rai, Renata Welc-Falęciak, Agnieszka Pawełczyk, Lucas S. Blanton, Aleš Chrdle, Andrea Fořtová, Daniel Růžek, Gheyath K. Nasrallah, Laith J. Abu-Raddadi, Duaa W. Al-Sadeq, Marah Abed Alhakim Abdallah, Daniele Lilleri, Chiara Fornara, Piera D’Angelo, Milena Furione, Maria Söderlund-Venermo, Klaus Hedman, Dimosthenis Chochlakis, Eirini Makridaki, Artemis Ntoula, Anna Psaroulaki, Angélica Escárcega-Ávila, John J. Rajasekaran

“…Our microarray in its present form can accommodate 400 antigens (molecules that can bind to specific antibodies) and can multiplex across antigen types, whole cell lysates, recombinant proteins, and peptides. A designed array containing multiple antigens of several microbes including Borrelia burgdorferi, the Lyme disease spirochete, was manufactured and evaluated. …”
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Identification of Loci under Selection by Combining Different Methods in Thoroughbred and Turkmen Horses by Milad Hosseini, Hossein Moradi-shahrbabak

“…Genotyping of the samples was done using 60 K arrays from Illumina company at the University of Kentucky. …”
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