Overcoming barriers to recruitment and retention of African–American women with SLE in behavioural interventions: lessons learnt from the WELL study by S Sam Lim, Gaobin Bao, Cristina Drenkard, Kirk Easley, Charmayne Dunlop-Thomas, Teresa Brady

“…The CDSMP is a 6-week, group-based programme led by peers to enhance self-management skills in people with chronic conditions. …”
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Harnessing new mHealth technologies to Strengthen the Management of Multidrug-Resistant Tuberculosis in Vietnam (V-SMART trial): a protocol for a randomised controlled trial by Ben J Marais, Joel Negin, James Johnston, Virginia Wiseman, Greg J Fox, Thu Anh Nguyen, Binh Hoa Nguyen, Viet Nhung Nguyen, Justin Beardsley, Guy Barrington Marks, Kavindhran Velen, Tho Dang, Hoang Anh Nguyen, Dinh Hoa Vu, Thu Thuong Do, Cuong Pham Duc, Huu Lan Nguyen, Huu Thuong Pham, Warwick Britton

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EXamining the feasibility of exerCisE to manage symptoms of Lupus (EXCEL): a protocol for a randomised controlled pilot study by John Reynolds, Katie Hesketh, Matthew Cocks, Megan Quickfall, Alex J Wadley, Scott Green, Jet Veldhuijzen Van Zanten

“…EXCEL will examine the feasibility of conducting a large-scale randomised controlled trial comparing the effects of a remotely monitored, home-based, exercise programme with standard of care for individuals with SLE.Methods and analysis 30 females with SLE will be recruited, and those randomised into Exercise (SLE-Ex) will codesign a progressive training plan with support from the research team. …”
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NeoTRACK trial: Neoadjuvant TiRagolumab, Atezolizumab and Chemotherapy – dissection of IO- efficacy in NSCLC by longitudinal tracKing – protocol of a non-randomised, open-label, si... by Albrecht Stenzinger, Farastuk Bozorgmehr, Michael Thomas, Hauke Winter, Michael Allgäeuer, Alexander Schramm, Servet Bolukbas, Marietta Kirchner, Martin Schuler, Petros Christopoulos, Marc Schneider, Romina M Roesch, Johannes Schnorbach, Laura V Klotz, Raffaella Griffo, Marcel Wiesweg, Fabian Doerr, Balazs Hegedüs, Jelena Cvetkovic, Martin E Eichhorn, Florian Eichhorn

“…The concept of treatment personalisation based on postoperative pCR is of great clinical interest.Ethics and dissemination The trial obtained ethical and regulatory approval in Germany through the Clinical Trials Information System (CTIS, ID: 2022-501322-38-00) and the Paul Ehrlich Institute (PEI, competent authority for approval of clinical trials using medicinal products for human use in Germany, process number: PB00148) on 30 March 2023. A data safety and monitoring board will meet regularly to review ongoing treatment in terms of safety.Study results will be published in peer-reviewed journals, presented at conferences and in the public registry of CTIS, following trial completion.Trial registration number NCT05825625.…”
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Hybrid closed-loop systems for managing blood glucose levels in type 1 diabetes: a systematic review and economic modelling by Asra Asgharzadeh, Mubarak Patel, Martin Connock, Sara Damery, Iman Ghosh, Mary Jordan, Karoline Freeman, Anna Brown, Rachel Court, Sharin Baldwin, Fatai Ogunlayi, Chris Stinton, Ewen Cummins, Lena Al-Khudairy

“…The system includes a combination of real-time continuous glucose monitoring from a continuous glucose monitoring device and a control algorithm to direct insulin delivery through an insulin pump. …”
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Telemedicine-supported hospital-at-home for acutely admitted patients at Nordsjaellands Hospital, Denmark: a study protocol for a randomised controlled trial by Maria Normand Larsen, Tatjana Sandreva Dreisig, Maja Kjaer Rasmussen, Maria Lund Christensen, Daniel Bjerregaard, Charlotte Demuth von Sydow, Thyge Lynghøj Nielsen, Thea Kølsen Fischer

“…To address these challenges, a hospital-at-home (HaH) programme offers an alternative to conventional in-hospital admission. …”
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Evaluation of Artesunate-mefloquine as a Novel Alternative Treatment for Schistosomiasis in African Children (SchistoSAM): protocol of a proof-of-concept, open-label, two-arm, indi... by Emmanuel Bottieau, Achilleas Tsoumanis, Yven Van Herrewege, Diana Arango, Christophe Burm, Badara Cisse, Souleymane Mboup, Clémentine Roucher, Isabel Brosius, Moustapha Mbow, Babacar Thiendella Faye, Annelies De Hondt, Bart Smekens, Linda Paredis, Idzi Potters, Katja Polman

“…The exclusive use of praziquantel (PZQ) in mass drug administration programmes may result in the emergence of drug resistance. …”
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Protocol for an observational study to identify potential predictors of an acute exacerbation in patients with chronic obstructive pulmonary disease (the PACE Study) by Klaus Kenn, Paul W Jones, Carmen Schade-Brittinger, Rainer Gloeckl, Daniela Leitl, Tessa Schneeberger, Inga Jarosch, Wolfgang Hitzl, Peter Alter, Bernd Sczepanski, Sandra Winterkamp, Martina Boensch, Chrysanthi Skevaki, Olaf Holz, Claus F Vogelmeier, Andreas R Koczulla

“…The results will be presented in conferences and published in a peer-reviewed journal.Trial registration number NCT04140097.…”
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A process evaluation of the walking in ScHools (WISH) study using the RE-AIM framework by Angela Carlin, Leanne C. Doherty, S. Maria O’Kane, Russell Jago, Ian M. Lahart, Gary McDermott, Maria Faulkner, Alison M. Gallagher, Marie H. Murphy

“…Schools are important settings for physical activity interventions. The WISH Study was a peer-led, school-based walking intervention that aimed to increase physical activity levels of adolescent girls. …”
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Efficacy of sensorimotor training combined with core strength training for low back pain in adult idiopathic scoliosis: a study protocol for a randomized controlled trial by Tongtong Zhang, Xin Li, Xuan Zhou, Nan Chen, Qing Du, Hong Yu, Xiaoqing Zhu, Qimeng Fan, Juping Liang, Zhengquan Chen, Xiangyue Zhou

“…Sessions will be conducted in the hospital, and no home programme will be provided. Adherence and attendance will be monitored and recorded. …”
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Quasiexperimental intervention study protocol to optimise the use of new antibiotics in Spain: the NEW_SAFE project by Jesús Rodríguez-Baño, Zaira R Palacios-Baena, Clara M Rosso-Fernández, Pilar Retamar, Lucia Valiente de Santis, Natalia Maldonado, Irene Borreguero, Carmen Herrero-Rodríguez, Salvador López-Cárdenas, Franciso J Martínez-Marcos, Andrés Martín-Aspas, Patricia Jiménez-Aguilar, Juan J Castón, Guillermo Ojeda-Burgos, M Pilar Aznarte-Padial, Julia Praena-Segovia, Juan E Corzo-Delgado, M Ángeles Esteban-Moreno

“…Their use should be supervised and monitored as part of an antimicrobial stewardship programme (ASP). …”
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Key factors for effective implementation of healthcare workers support interventions after patient safety incidents in health organisations: a scoping review by Helena Donato, José Joaquín Mira, Irene Carrillo, Paulo Sousa, Sofia Guerra-Paiva, Maria João Lobão, Diogo Godinho Simões, Joana Fernandes

“…Regular communication among the implementation team, allocation of protected time, funding and continuous monitoring are useful elements to the sustainability of the programmes.Conclusion HCWs’ well-being depends on an adequate implementation of a complex group of interrelated factors to support them after PSIs.…”
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Interventions for physician prescribers of opioids for chronic non-cancer pain: protocol for an overview of systematic reviews by Brett D Thombs, Sonia Johnson, Kristian B Filion, Andrew Taylor, Jonathan Kimmelman, Erica Wennberg, Genevieve Gore, Irina Kudrina, Mark J Eisenberg, Sarah B Windle, Elena Paraskevopoulos, Marc O Martel

“…Systematic reviews have evaluated effects of specific interventions (eg, prescriber education, prescription drug monitoring programmes) on patient and population health outcomes and prescriber behaviour. …”
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Protocol for a phase IV double-blind randomised controlled trial to investigate the effect of the 13-valent pneumococcal conjugate vaccine and the 23-valent pneumococcal polysaccha... by Tao Chen, Duolao Wang, Konstantinos Liatsikos, Stephen B Gordon, Hassan Burhan, Ben Morton, Tinashe K Nyazika, Bradford D Gessner, Helen Hill, Andrea Collins, Josh Hamilton, Kelly Davies, Fred Fyles, Phoebe Hazenberg, Elizabeth Begier, Angela Hyder-Wright, Sherin Pojar, Christopher Myerscough, Jesus Reine, Ryan E Robinson, Britta Urban, Elena Mitsi, Carla Solorzano, Angela Quinn, Kaijie Pan, Annaliesa S Anderson, Christian Theilacker, Daniela M Ferreira, Kelly Convey, James Court, Madlen Farrar, Lisa Hitchins, Ashleigh Howard, Lauren Kerruish, Samuel Latham, Annabel Murphy, Elissavet Nikolaou, Angelina Peterson

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Protocol of the TransformUs Secondary schools program: a type II hybrid implementation-effectiveness trial to increase adolescents’ physical activity and reduce sedentary time in s... by Harriet Koorts, Anna Timperio, Jo Salmon, David Revalds Lubans, Gavin Abbott, Nicola D Ridgers, Natalie Lander, Ana María Contardo Ayala, Emiliano Mazzoli

“…TransformUs, an effective and cost-effective whole-of-school programme for promoting primary school children’s physical activity and reducing sedentary behaviour, has been adapted for secondary schools (TransformUs Secondary). …”
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Developing a Quality Improvement Framework to Enhance the Health System User Experience for Individuals Living With Type 1 Diabetes: The Reshape T1D Study by Jamie Boisvenue, Youssef A. Elezzabi, Kim Young, Kathleen Gibson, Heather Hinz, Reid McClure, Robyn Homulos, Jude Spiers, Peter Senior, Roseanne Yeung

“…Diabetes online communities provide an adjunct to clinical care through peer support. Cost and access to the latest technology are ongoing barriers for many participants, especially concerning publicly funded programmes that use advanced insulin pump therapy, continuous glucose monitoring, and automated insulin delivery systems. …”
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Unlocking the transformative potential of data science in improving maternal, newborn and child health in Africa: a scoping review protocol by Eric Ohuma, Agbessi Amouzou, Abiy Seifu Estifanos, Phillip Wanduru, Samson Yohannes Amare, Joseph Akuze, Bancy Ngatia, Grieven P Otieno, Rornald M Kananura, Kirakoya-Samadoulougou Fati

“…They will also propose next steps for integrating data science in MNCH programmes in Africa. The implications of our findings will be examined in relation to possible methods for enhancing data science in MNCH, such as community and clinical settings, monitoring and evaluation. …”
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Brazilian network of COVID-19 during pregnancy (REBRACO: a multicentre study protocol) by Elias F Melo Júnior, Renato T Souza, José Guilherme Cecatti, Renato Passini Jr, Jussara Mayrink, Maria Laura Costa, Debora F Leite, Janete Vettorazzi, Ricardo P Tedesco, Fernanda G Surita, Rodolfo C Pacagnella, Carla B Andreucci, Marcos Nakamura-Pereira, Marcos Augusto Bastos Dias, Luis Bahamondes, Maria J Miele, Karayna G Fernandes, Silvana F Bento, Carolina C Ribeiro-do-Valle, Adriana G Luz, Giuliane J Lajos, Silvia B Mazon, Guilherme M Nobrega, Thayna B Griggio, Charles M'poca Charles, Sergio Martins-Costa, Frederico JA Peret, Francisco E Feitosa, Rosiane Mattar, Evelyn Traina, Edson V Cunha Filho, Samira M Haddad, José Paulo Guida, Mario D Correa Junior, Leandro G Oliveira, Carlos AS Menezes, Marília GQ Luz, Sherly Metelus, Lester Castro, Stephanie Pabon, Rachel Soeiro, Amanda D Silva, Paulo S R Junior, Thais G Sardinha, Rodolfo R Japenga, Erica R F Urquiza, Maíra R Machado, Marcela Maria Simões, Larissa M Solda, Sue Yazaki-Sun, Priscilla Mota, Arimaza C Soares, Ellen Machado, Anne Bergmann, Gustavo Raupp dos Santos, Patrícia B Peres, Cristiane L Arbeli, Rafael M Quevedo, Carolina F Yamashita, Julia D Corradin, Isabella Bergamini, José Geraldo L Ramos, Maria Lúcia R Oppermann, Laisa S Quadro, Lina Marins, Érika V Paniz, Thaís Vicentini Xavier, Bruna E Parreira, Aline Tosetto, Sabrina Savazoni, Aline C Costa, Marina HL Almeida, Bruna FV Moura, Lidiane R França, Hanna Vieira, Rafael B Aquino, Isabella Monteiro, Bruna O Guerra, Gabriela Gorga, Daisy Pinheiro, Denise Cordeiro, Priscila L Miná, Carol Dornellas, Kevin FA Oliveira, Caio Leal, Rayra Amana, Cristiane O Santos, Marina M dos Santos, Carlos Neto, Thiago Gomes, Isabela R Pereira, Clélia Andrade Salustrino, Valéria B Pontes, Roberto Allen da Silva Franco, João Paolo Bilibio, Gislânia PF Brito, Hana Paula C Pinto, Danielle Leal de Oliveira, Andrezza A Guerra, Andrea O Moura, Natasha Pantoja, Fernanda David, Alina Silva, Juliana Vasconcellos Freitas-Jesus, Angela M Bacha, Anderson Borovac-Pinheiro, Belmiro G Pereira, Eliana M Amaral, Elton Carlos Ferreira, Helaine MBPM Milanez, Jamil P S Caldas, Luiz F Baccaro, Marcelo L Nomura, Patrícia M Rehder, Renata Z Simone, Cristiano Torrezan, Jose L P Modena, Magnun N Nunes dos Santos, Sergio T M Marba, Tabata Z Dias, Mariana EV

“…Findings will be disseminated through peer-reviewed journals and scientific conferences.…”
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Evaluating the population impact of hepatitis C direct acting antiviral treatment as prevention for people who inject drugs (EPIToPe) – a natural experiment (protocol) by Jeremy Horwood, Andrew Radley, John F Dillon, Peter Vickerman, Rory N Gunson, Mary Ramsay, Chris Metcalfe, William Hollingworth, Hannah Fraser, Helen Harris, Ellen Heinsbroek, Lawrie Elliott, Paul Flowers, Sema Mandal, Matthew Hickman, David Goldberg, Natasha Martin, Emma Hamilton, Daniela De Angelis, Graham Foster, Peter Donnan, Ann Eriksen, Samreen Ijaz, David Liddell, Lewis J Z Beer, Kate Drysdale, Rachel Glass, Lesley Graham, Ross Harris, Vivian Hope, Sarah Karen Inglis, Hamish Innes, Athene Lane, Jade Meadows, Andrew McAuley, Stephanie Migchelsen, Alex Murray, Gareth Myring, Norah E Palmateer, Anne Presanis, Pantelis Samartsidis, Ruth Simmons, Katy Sinka, Gabriele Vojt, Zoe Ward, David Whiteley, Alan Yeung, Sharon J Hutchinson

“…The primary outcome – chronic HCV prevalence in PWID – is measured using information from the Needle Exchange Surveillance Initiative survey in Scotland and the Unlinked Anonymous Monitoring Programme in England, conducted at least four times before and three times during and after the intervention. …”
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Exploring voluntary sector specialist services for victim-survivors of sexual violence in England: the PROSPER co-production study by Caroline Bradbury-Jones, Sarah Damery, Kirsten Fruin, Clare Gunby, Jenny Harlock, Lucy Hebberts, Louise Isham, Anne-Marie Jones, Fay Maxted, Amelia Mighty, Priti Parmar, Laura Patterson, Jason Schaub, Fee Scott, Harriet Smailes, Debs Smith, Julie Taylor

“…Explore the usefulness of different approaches to service delivery (including peer support and delivery by volunteers) and different therapy models. …”
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