Cutting the Difficult Papilla: Ancillary Techniques in the Performance of Endoscopic Sphincterotomy by Claude Liguory, Jean Francois Lefebvre, Didier Bonnel, Gary C Vitale

“…There were five deaths (mortality rate 0.5%) and laparotomy was required in six patients (0.6%). Conditions contributing to complications included an intradiverticular papilla and precutting. …”
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Synthetic Peptides as Potential Antigens for Cutaneous Leishmaniosis Diagnosis by Juliana Seger Link, Silvana Maria Alban, Carlos Ricardo Soccol, Gilberto Vinicius Melo Pereira, Vanete Thomaz Soccol

“…In order to reach the goal, we used random peptide phage display libraries screened using antibodies from Leishmania braziliensis patients. After selection, three peptides (P1, P2, and P3) were synthesized using Fmoc chemistry. …”
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Intravitreal Clindamycin and Dexamethasone Combined with Systemic Oral Antitoxoplasma Therapy versus Intravitreal Therapy Alone in the Management of Toxoplasma Retinochoroiditis: A... by Ashraf Bor’i, Ashraf Mahrous, Mahmoud A. Al-Aswad, Haitham Y. Al-Nashar, Waled M. Nada, Mostafa Wagih, Ahmed M. B. Awad, Wael M. El-Haig

“…To compare clinical outcome of IVCD combined with oral therapy with IVCD alone in patients with toxoplasmic retinochoroiditis. Patients and Methods. …”
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Acute Portal Vein Thrombosis Treated with Recombinant Human Soluble Thrombomodulin Combined with Antithrombin III by Satoshi Nakayama, Naoya Murashima

“…Portal vein thrombosis is a major complication associated with liver cirrhosis. In cirrhotic patients, a decrease in procoagulant and anticoagulant factors and an unstable balance between them is observed, and a relative decrease in the activation of anticoagulant drivers is one of the main causes of portal vein thrombosis (PVT). …”
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Azithromycin in the Management of Upper Respiratory Tract Infections (URTIs): Indian Real-Life Experience by Dominic M, Srivastava R, Shah K, Naik SM, Rout K, Ray B, Patil D, Rana D, Swami OC

“…Proportion of patients reporting sore throat was reduced from 95.8% to 10.4%; work absenteeism dropped from 47.9% to 1%; and fever subsided in 97.4% of patients. …”
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Cell-Based Therapy for Cerebral Palsy: A Puzzle in Progress by Masoumeh Nouri, Morteza Zarrabi, Safdar Masoumi, Elaheh Khodadoust, Anahita Majmae, Man Amanat, Mahmoud Reza Ashrafi, Massoud Vosough

“…However, there is noconsensus on a standard therapeutic protocol regarding the source of cells, optimal cell dose, timing and frequencyof cell injections, route of administration, or the use of combination therapy. …”
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Effectiveness of Antiviral Treatment with Intravenous Peramivir and Oral Oseltamivir for Seasonal Influenza in Children by Young-hoon Byun, Ji-Eun Kim, So-Hyun Paek, Min-Jung Kim, Soo Hyun Park, Ho-Young Song, Jaehyun Kwon

“…Results: A total of 1327 pediatric patients were included, with 1243 receiving oseltamivir and 84 receiving peramivir. …”
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Fecal Microbiota Transplantation as Therapy for Treatment of Active Ulcerative Colitis: A Systematic Review and Meta-Analysis by Xiaolei Liu, Yan Li, Kaichun Wu, Yongquan Shi, Min Chen

“…FMT delivered via lower gastrointestinal route was superior to upper gastrointestinal route with regard to combined clinical remission with endoscopic remission/response (RR=0.79, 95% CI 0.70-0.89). …”
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Survey of Traveler’s Diarrhea: Epidemiology and Testing Reveal the Source by Zhenguo Gao, Muti Mahe, Shabiremu Tuohetamu, Fang Li, Jian Zhang, Yidan Xia, Xiaona Sun, Abuzhalihan Naerkezi, Ruifang Huang, Hongbin Liu, Daxin Ni, Rong Zhang

“…To understand the causes and transmission routes of, as well as risk factors, for a Salmonella outbreak in a tour group. …”
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Abuse potential of fentanyl and fentanyl analogues by Anusha Thumma, Kwadwo Mfoafo, Niloofar Babanejad, Alborz Omidian, Yadollah Omidi, Hamid Omidian

“…Introduction: In this perspective review, we evaluated the clinical management of fatal fentanyl overdose in several routes of administration, concentrating on both legally prescribed and illegally produced formulations. …”
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Assessment of Hand-Washing Knowledge and Practice among Nursing Undergraduates in Saudi Arabia by Wajid Syed, Mahmood Basil A. Al-Rawi

“…The present results could support students and health care professionals in improving their hygienic practice, which may help to provide the optimum therapeutic benefits to patients.…”
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Occult Perforation of the Esophagus during Removal of an Enteral Feeding Tube: A Case Report and Literature Review by Mohammad Alabdallat, Gustav Strandvik, Ibrahim Afifi, Ruben Peralta, Ashok Parchani, Ayman El-Menyar, Sandro Rizoli, Hassan Al-Thani

“…The use of oral or nasal route for enteral feeding is a standard practice in intensive care patients with a safe profile in general. …”
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Characterization of acute intoxications in Sancti Spíritus pediatric age, 2014-2018 by Yarelyn Prieto Amude, Karen Remedios Rodríguez, Yanicel Sorí León, Yaumara María León Águila, Raylen Escobar Román

“…The information was obtained through the review of all the medical records of the admitted patients. The variables age, sex, type of circumstantial poisoning, whether intentional or not, place of occurrence; routes of exposure, hospital stay and responsible agent were analyzed. …”
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Inhaled Drug Delivery: A Practical Guide to Prescribing Inhaler Devices by Pierre Ernst

“…Asthma education will be needed to instruct patients on the effective use of the numerous inhalation devices available.…”
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Intravenous versus subcutaneous tocilizumab in Takayasu arteritis: multicentre retrospective study by Patrice Cacoub, Arsène Mekinian, David Saadoun, Pavel I Novikov, Savino Sciascia, Corrado Campochiaro, Olivier Fain, Ilya Smitienko, Nicolas Schleinitz, Patrick Jégo, Francesco Muratore, Carlo Salvarani, Elena Galli, Sabine Berthier, Marc Lambert, François Maurier, Isabelle Kone-Paut, Sergey Moiseev, Masataka Kuwana, Alexandre Belot, Martin Michaud, Francis Gaches, Achille Aouba, Xavier Puechal, Karim Sacre, Tiphaine Goulenok, Alessandro Tomelleri, Thomas Sené, Elena Marina Baldissera, Luigi Boiardi, Abid Awisat, Ygal Benhamou, Vahan Mukuchyan, Mathieu Vautier, Azeddine Dellal, Lucie Biard, Julie Seguier, José Hernández-Rodríguez, Olivier Espitia, Sebastien Humbert, Guillaume Denis, Nolan Hassold, Dagna Lorenzo, Helene Munoz Pons, Jean Baptiste Gaultier, Le Mouel Edwige, Antoinette Perlat, Bertrand Lioger, Jonathan Broner, Virginie Dufrost, Faten Frikha, Alexandra Audemard-Verger, Pascal Woaye-Hune, Pierre Zeminsky, Moya Alvarado, Matheus Vieira, Alberto Lo Gullo

“…Adverse events occurred in 14 (15%) patients on intravenous route and in 2 (11%) on SC tocilizumab.Conclusion In this study, we confirm that tocilizumab is effective in TAK, with complete remission being achieving by 70% of disease-modifying antirheumatic drugs-refractory TAK patients at 6 months.…”
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Two Atypical Cases of Hantavirus Infections from Sri Lanka by N. D. B. Ehelepola, B. M. L. S. Basnayake, S. M. B. Y. Sathkumara, K. L. R. Kaluphana

“…Having arrived at the correct diagnosis late/retrospectively, both these patients recovered notwithstanding being seriously ill, indicating adequate supportive therapy can save lives in such cases. …”
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The role of dendritic cells in tertiary lymphoid structures: implications in cancer and autoimmune diseases by Mariana Reste, Kristi Ajazi, Ayca Sayi-Yazgan, Ayca Sayi-Yazgan, Radmila Jankovic, Biljana Bufan, Sven Brandau, Espen S. Bækkevold, Florent Petitprez, Malin Lindstedt, Gosse J. Adema, Catarina R. Almeida

“…Therefore, it is important to analyze the complex functions of DCs within TLS in order to enhance our fundamental understanding of immune regulation but also as a possible route to create innovative clinical interventions designed for the specific needs of patients with diverse pathological diseases.…”
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MOLECULAR CHARACTERIZATION OF CARBAPENEM RESISTANT KLEBSIELLA PNEUMONIAE AT A TERTIARY CARE LABORATORY IN KERALA, INDIA by Swapna C. Senan, Jithu Paul Jacob, Ramani Bhai

“…Background: Isolates of Klebsiella pneumoniae resistant to Carbapenem appears to be most commonly transmitted by hospitalized patients. This may cause infections which lead to mortality. …”
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Recombinant production platform for Group A Streptococcus glycoconjugate vaccines by Sowmya Ajay Castro, Ian J. Passmore, Didier Ndeh, Helen Alexandra Shaw, Alessandro Ruda, Keira Burns, Sarah Thomson, Rupa Nagar, Kathirvel Alagesan, Mark Reglinski, Kieron Lucas, Sherif Abouelhadid, Ulrich Schwarz-Linek, Fatme Mawas, Göran Widmalm, Brendan W. Wren, Helge C. Dorfmueller

“…Abstract Group A Streptococcus (Strep A) is a human-exclusive bacterial pathogen killing annually more than 500,000 patients, and no current licensed vaccine exists. Strep A bacteria are highly diverse, but all produce an essential, abundant, and conserved surface carbohydrate, the Group A Carbohydrate, which contains a rhamnose polysaccharide (RhaPS) backbone. …”
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COVID-19: Gastrointestinal Manifestations and Complications by Angel Yun-Kuan Thye, Priyia Pusparajah, Loh Teng-Hern Tan, Jodi Woan-Fei Law, Vengadesh Letchumanan, Learn-Han Lee

“…However, mounting evidence demonstrates detection of SARS-CoV-2 RNA in stool samples of COVID-19 patients. It has also been demonstrated that the host receptor angiotensin-converting-enzyme-2 (ACE-2) is highly expressed not just in respiratory cells but also in gastrointestinal sites involving the glandular cells of gastric, duodenal, and rectal epithelium. …”
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