-
501
Extracellular Vesicle-Integrated Biomaterials in Bone Tissue Engineering Applications: Current Progress and Future Perspectives
Published 2025-06-01“…Yan Huang,1 Hui Xie2 1Department of Rehabilitation Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000 People’s Republic of China; 2Department of Geriatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000 People’s Republic of ChinaCorrespondence: Hui Xie, Email xiehuijessice@163.comAbstract: With an aging population and increased life expectancy, the clinical burden of bone-related disorders, especially large bone defects, continues to grow, underscoring the urgent need for effective regenerative strategies. Effective bone regeneration is essential not only for restoring skeletal structure and function but also for improving patients’ quality of life and reducing the socioeconomic burden associated with prolonged recovery or surgical failure. …”
Get full text
Article -
502
Perinatal interventions to prevent Adverse Childhood Experiences (ACEs): A scoping review.
Published 2024-01-01“…Interventions with the strongest evidence based on study quality and reported outcomes were co-parenting programs designed to improve the quality and function of the co-parenting relationship, home visiting interventions, and integrative health interventions incorporating baby massage and/or yoga. …”
Get full text
Article -
503
Identification of long InDels through whole genome resequencing to fine map qIF05-1 for seed isoflavone content in soybean (Glycine max L. Merr.)
Published 2025-01-01“…A total of 10,002 long InDels (15.85% of total) were located in genic regions, including 1,139 large-effect long InDels which resulted in truncated or elongated protein sequences. …”
Get full text
Article -
504
Digital augmentation of aftercare for patients with anorexia nervosa: the TRIANGLE RCT and economic evaluation
Published 2025-07-01“…Fathers in the spotlight: parental burden and the effectiveness of a parental skills training for anorexia nervosa in mother–father dyads. …”
Get full text
Article -
505
Adipocyte/Tumor cell crosstalk via IGF-1/TXNIP axis promotes malignancy and endocrine resistance in breast cancer
Published 2025-06-01“…Results In a model of co-culture, we demonstrated that conditioned media (CM) released by 3T3-L1A adipocytes reduced the sensitivity of parental MCF-7 BC cells to the inhibitory effects of Tamoxifen (Tam) on growth, motility and invasion and significantly increased the proliferative, motile and invasive phenotype of Tam-resistant (TR) BC cells. …”
Get full text
Article -
506
Whole-Body Biodistribution, Dosimetry, and Metabolite Correction of [C]Palmitate: A PET Tracer for Imaging of Fatty Acid Metabolism
Published 2017-10-01“…Results: In humans, mean effective dose was 3.23 (0.02) µSv/MBq, with the liver and myocardium receiving the highest absorbed doses. …”
Get full text
Article -
507
The Assistant Еducator – a Valuable Resource in the Care, Education and Socialization of Kindergarten Children
Published 2022-09-01“…Effective use of such resource would help to increase the quality of the educational process.…”
Get full text
Article -
508
Fuzzy Guiding of Roulette Selection in Evolutionary Algorithms
Published 2025-02-01“…The algorithm can be an effective tool in solving a wide range of optimization problems, for example, optimization of computer network infrastructure.…”
Get full text
Article -
509
Development of Speech Therapy Application for Children with Stuttering (STACS)
Published 2025-09-01“…Regarding the app's functionality, nearly 77% of parents found it highly satisfying. …”
Get full text
Article -
510
Constructing 1 + 1 > 2 Photosensitizers Based on NIR Cyanine–Iridium(III) Complexes for Enhanced Photodynamic Cancer Therapy
Published 2025-06-01“…It is demonstrated that <b>CHO−Ir−Cy</b> successfully maintains the NIR absorption and emission originated from cyanine units and high <sup>1</sup>O<sub>2</sub> generation efficiency from the iridium complex part, which gives full play to their respective advantages while compensating for shortcomings. Density functional theory (DFT) calculations reveal that <b>CHO−Ir−Cy</b> exhibits a stronger spin–orbit coupling constant (ξ (S1, T1) = 9.176 cm<sup>−1</sup>) and a reduced energy gap (ΔE = −1.97 eV) between triplet excited states (T<sub>1</sub>) and first singlet excited states (S<sub>1</sub>) compared to parent Ir−Cy or Cy alone, directly correlating with its enhanced <sup>1</sup>O<sub>2</sub> production. …”
Get full text
Article -
511
Softening of dd excitation in the resonant inelastic x-ray scattering spectra as a signature of Hund's coupling in nickelates
Published 2025-03-01“…We investigate the effects of Hund's coupling on the resonant x-ray absorption spectra of the recently discovered family of layered nickelate superconductors. …”
Get full text
Article -
512
Adaptive component crossover for differential evolution in solving single-objective optimization problems
Published 2025-01-01“…With the increase of the complexity of engineering problems, evolutionary algorithms became an effective approach to black-box optimization problems. …”
Get full text
Article -
513
Landscape and variation of novel retroduplications in 26 human populations.
Published 2017-06-01“…Based solely on retroduplication variation, we built phylogenetic trees of human populations; these represent superpopulation structure well and indicate that variable retroduplications are effective population markers. We further identified 43 retroduplication parent genes differentiating superpopulations. …”
Get full text
Article -
514
Oversharing Behavior in Gen Z on Social Media
Published 2025-01-01“…Future research should examine the long-term effects of oversharing on Generation Z and explore effective interventions to enhance digital resilience.…”
Get full text
Article -
515
Improving Genetic Algorithm with Fine-Tuned Crossover and Scaled Architecture
Published 2016-01-01“…It differentiates itself by inheriting entirely from the female, while the rest of the DNA is inherited equally from both parents. This unique characteristic of mtDNA can be an effective mechanism to identify members with similar genes and restrict crossover between them. …”
Get full text
Article -
516
Educating Student Teachers to Become High Quality Professionals – A Finnish Case
Published 2011-03-01“…Finnish pre-service teacher education seems to function very well and to be effective in providing the skills teachers need to work as independent professionals. …”
Get full text
Article -
517
STAT2/SLC27A3/PINK1-Mediated Mitophagy Remodeling Lipid Metabolism Contributes to Pazopanib Resistance in Clear Cell Renal Cell Carcinoma
Published 2024-01-01“…The differential expression of SLC27A3 and its effect on drug resistance of ccRCC tumor were detected in vitro and in vivo. …”
Get full text
Article -
518
Evaluation of the diet of a selected group of children with coeliac disease
Published 2024-12-01Get full text
Article -
519
Chatbot Informasi Penerimaan Mahasiswa Baru Menggunakan Metode FastText dan LSTM
Published 2024-02-01“…The results of this study are expected to be an effective and consistent solution for providing information about PMB to prospective students and parents/guardians of prospective students at FSI. …”
Get full text
Article -
520
Educating Student Teachers to Become High Quality Professionals – A Finnish Case
Published 2018-01-01“…Finnish pre-service teacher education seems to function very well and to be effective in providing the skills teachers need to work as independent professionals. …”
Get full text
Article