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  1. 501

    Extracellular Vesicle-Integrated Biomaterials in Bone Tissue Engineering Applications: Current Progress and Future Perspectives by Huang Y, Xie H

    Published 2025-06-01
    “…Yan Huang,1 Hui Xie2 1Department of Rehabilitation Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000 People’s Republic of China; 2Department of Geriatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000 People’s Republic of ChinaCorrespondence: Hui Xie, Email xiehuijessice@163.comAbstract: With an aging population and increased life expectancy, the clinical burden of bone-related disorders, especially large bone defects, continues to grow, underscoring the urgent need for effective regenerative strategies. Effective bone regeneration is essential not only for restoring skeletal structure and function but also for improving patients’ quality of life and reducing the socioeconomic burden associated with prolonged recovery or surgical failure. …”
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  2. 502

    Perinatal interventions to prevent Adverse Childhood Experiences (ACEs): A scoping review. by Jane Kinsey, Jaime La Charite, Shirley Russ, Adam Schickedanz

    Published 2024-01-01
    “…Interventions with the strongest evidence based on study quality and reported outcomes were co-parenting programs designed to improve the quality and function of the co-parenting relationship, home visiting interventions, and integrative health interventions incorporating baby massage and/or yoga. …”
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  3. 503

    Identification of long InDels through whole genome resequencing to fine map qIF05-1 for seed isoflavone content in soybean (Glycine max L. Merr.) by Jia Jia, Huan Wang, Ximeng Yang, Bo Chen, Ruqian Wei, Qibin Ma, Yanbo Cheng, Hai Nian

    Published 2025-01-01
    “…A total of 10,002 long InDels (15.85% of total) were located in genic regions, including 1,139 large-effect long InDels which resulted in truncated or elongated protein sequences. …”
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  4. 504

    Digital augmentation of aftercare for patients with anorexia nervosa: the TRIANGLE RCT and economic evaluation by Janet Treasure, Katie Rowlands, Valentina Cardi, Suman Ambwani, David McDaid, Jodie Lord, Danielle Clark Bryan, Pamela Macdonald, Eva Bonin, Ulrike Schmidt, Jon Arcelus, Amy Harrison, Sabine Landau

    Published 2025-07-01
    “…Fathers in the spotlight: parental burden and the effectiveness of a parental skills training for anorexia nervosa in mother–father dyads. …”
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  5. 505

    Adipocyte/Tumor cell crosstalk via IGF-1/TXNIP axis promotes malignancy and endocrine resistance in breast cancer by Amanda Caruso, Felice Maria Accattatis, Cinzia Giordano, Luca Gelsomino, Piercarlo Del Console, Maria Francesca Fiorita, Balazs Gyorffy, Laura Bianchi, Alfonso Carleo, Rossana De Salvo, Bruno M Simões, Robert B Clarke, Lorenzo Memeo, Cristina Colarossi, Eleonora Aiello, Francesco Conforti, Suzanne A W Fuqua, Matilde Todaro, Giorgio Stassi, Catia Morelli, Diego Sisci, Daniela Bonofiglio, Stefania Catalano, Sebastiano Andò, Ines Barone

    Published 2025-06-01
    “…Results In a model of co-culture, we demonstrated that conditioned media (CM) released by 3T3-L1A adipocytes reduced the sensitivity of parental MCF-7 BC cells to the inhibitory effects of Tamoxifen (Tam) on growth, motility and invasion and significantly increased the proliferative, motile and invasive phenotype of Tam-resistant (TR) BC cells. …”
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  6. 506
  7. 507

    The Assistant Еducator – a Valuable Resource in the Care, Education and Socialization of Kindergarten Children by Aksenia Tileva

    Published 2022-09-01
    “…Effective use of such resource would help to increase the quality of the educational process.…”
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  8. 508

    Fuzzy Guiding of Roulette Selection in Evolutionary Algorithms by Krzysztof Pytel

    Published 2025-02-01
    “…The algorithm can be an effective tool in solving a wide range of optimization problems, for example, optimization of computer network infrastructure.…”
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  9. 509

    Development of Speech Therapy Application for Children with Stuttering (STACS) by Janith Raj Jayaraju, Amudhu Sankar

    Published 2025-09-01
    “…Regarding the app's functionality, nearly 77% of parents found it highly satisfying. …”
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  10. 510

    Constructing 1 + 1 > 2 Photosensitizers Based on NIR Cyanine–Iridium(III) Complexes for Enhanced Photodynamic Cancer Therapy by Ziwei Wang, Weijin Wang, Qi Wu, Dongxia Zhu

    Published 2025-06-01
    “…It is demonstrated that <b>CHO−Ir−Cy</b> successfully maintains the NIR absorption and emission originated from cyanine units and high <sup>1</sup>O<sub>2</sub> generation efficiency from the iridium complex part, which gives full play to their respective advantages while compensating for shortcomings. Density functional theory (DFT) calculations reveal that <b>CHO−Ir−Cy</b> exhibits a stronger spin–orbit coupling constant (ξ (S1, T1) = 9.176 cm<sup>−1</sup>) and a reduced energy gap (ΔE = −1.97 eV) between triplet excited states (T<sub>1</sub>) and first singlet excited states (S<sub>1</sub>) compared to parent Ir−Cy or Cy alone, directly correlating with its enhanced <sup>1</sup>O<sub>2</sub> production. …”
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  11. 511

    Softening of dd excitation in the resonant inelastic x-ray scattering spectra as a signature of Hund's coupling in nickelates by Umesh Kumar, Corey Melnick, Gabriel Kotliar

    Published 2025-03-01
    “…We investigate the effects of Hund's coupling on the resonant x-ray absorption spectra of the recently discovered family of layered nickelate superconductors. …”
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  12. 512

    Adaptive component crossover for differential evolution in solving single-objective optimization problems by Sopov Anton, Sopov Evgenii

    Published 2025-01-01
    “…With the increase of the complexity of engineering problems, evolutionary algorithms became an effective approach to black-box optimization problems. …”
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  13. 513

    Landscape and variation of novel retroduplications in 26 human populations. by Yan Zhang, Shantao Li, Alexej Abyzov, Mark B Gerstein

    Published 2017-06-01
    “…Based solely on retroduplication variation, we built phylogenetic trees of human populations; these represent superpopulation structure well and indicate that variable retroduplications are effective population markers. We further identified 43 retroduplication parent genes differentiating superpopulations. …”
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  14. 514

    Oversharing Behavior in Gen Z on Social Media by Edy Susilo Muhammad, Prayudi Prayudi, Yanu Florestiyanto Mangaras

    Published 2025-01-01
    “…Future research should examine the long-term effects of oversharing on Generation Z and explore effective interventions to enhance digital resilience.…”
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  15. 515

    Improving Genetic Algorithm with Fine-Tuned Crossover and Scaled Architecture by Ajay Shrestha, Ausif Mahmood

    Published 2016-01-01
    “…It differentiates itself by inheriting entirely from the female, while the rest of the DNA is inherited equally from both parents. This unique characteristic of mtDNA can be an effective mechanism to identify members with similar genes and restrict crossover between them. …”
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  16. 516

    Educating Student Teachers to Become High Quality Professionals – A Finnish Case by Hannele Niemi

    Published 2011-03-01
    “…Finnish pre-service teacher education seems to function very well and to be effective in providing the skills teachers need to work as independent professionals. …”
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  17. 517

    STAT2/SLC27A3/PINK1-Mediated Mitophagy Remodeling Lipid Metabolism Contributes to Pazopanib Resistance in Clear Cell Renal Cell Carcinoma by Dingheng Lu, Yuxiao Li, Xinyang Niu, Jiazhu Sun, Weitao Zhan, Yuchen Shi, Kai Yu, Suyuelin Huang, Xiaoyan Liu, Liping Xie, Xueyou Ma, Ben Liu

    Published 2024-01-01
    “…The differential expression of SLC27A3 and its effect on drug resistance of ccRCC tumor were detected in vitro and in vivo. …”
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  18. 518
  19. 519

    Chatbot Informasi Penerimaan Mahasiswa Baru Menggunakan Metode FastText dan LSTM by Fahmi Yusron Fiddin, Agus Komarudin, Melina Melina

    Published 2024-02-01
    “…The results of this study are expected to be an effective and consistent solution for providing information about PMB to prospective students and parents/guardians of prospective students at FSI. …”
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  20. 520

    Educating Student Teachers to Become High Quality Professionals – A Finnish Case by Hannele Niemi

    Published 2018-01-01
    “…Finnish pre-service teacher education seems to function very well and to be effective in providing the skills teachers need to work as independent professionals. …”
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    Article