ABCB1 confers resistance to carboplatin by accumulating stem-like cells in the G2/M phase of the cell cycle in p53null ovarian cancer by Danbi Lee, Hyun-Seok Jeong, Sun-Young Hwang, Yu-Gyeong Lee, Youn-Jung Kang

“…Notably, combinatorial treatment of carboplatin with the p53 reactivator, APR-246, proved effective in overcoming chemoresistance in OVCAR3 with the p53R248Q. …”
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FACTORS OF CARIES DEVELOPMENT AND WAYS TO REDUCE THEI IMPACT IN SCHOOL CHILDREN by L.F. Kaskova, T.B. Mandzyuk

“…Dental diseases in children, particularly dental caries, are still requiring approaches and methods of their effective prevention and treatment. Analysis of caries rates in 7 – 9 year children has revealed a probable increase in the prevalence and intensity of caries in permanent teeth over the past 20 years. …”
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Pilot Study of a Web-Delivered Multicomponent Intervention for Rural Teens with Poorly Controlled Type 1 Diabetes by Amy Hughes Lansing, Catherine Stanger, Alan Budney, Ann S. Christiano, Samuel J. Casella

“…SMBG was increased significantly at end of active and maintenance treatment, and HbA1c was decreased at end of active treatment (p’s ≤ 0.05). Executive functioning improved at end of maintenance treatment: performance on working memory and inhibitory control tasks significantly improved (p’s ≤ 0.02) and parents reported fewer problems with executive functioning (p=0.05). …”
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Serotonergic contribution to boys' behavioral regulation. by Amélie Nantel-Vivier, Robert O Pihl, Simon N Young, Sophie Parent, Stacey Ageranioti Bélanger, Rachel Sutton, Marie-Eve Dubois, Richard E Tremblay, Jean R Séguin

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Emotion dysregulation in adolescents is normalized by ADHD pharmacological treatment by Krisztina Kondi, Mária Takács, Evelyn Kovács-Posta, Claudia Szajli, Tünde Sebők-Welker, János M. Réthelyi, Nóra Bunford

“…First- and second-line ADHD pharmacotherapy is effective at ameliorating core symptoms and improving cognitive functioning and accumulating evidence indicates primairly in children and adults, active ADHD pharmacotherapy has beneficial effects on emotional symptoms. …”
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THEORETICAL ISSUES OF FORMATION OF MORAL VALUES OF STUDENT YOUTH IN THE REALITIES OF TODAY by Stanislav V. Sapozhnykov, Dovev Mark

“…The article identifies the following main theoretical problems of formation of moral values of student youth: the problem of coordination of teachers and parents educational influences on student youth in the process of their socialization and individualization; filling the methods of formation of educational activities with appropriate moral content; functioning of interrelation and mutual influence of personal qualities of student’s youth which are in a stage of their formation; creation of an effective model of formation of moral values of student youth which will consider the sequence of development of various qualities of a person. …”
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Prevention of school bullying as a factor in the safety of the educational environment by O.B. Krushelnitskaya, T.Y. Marinova, V.A. Orlov, V.B. Slastina

“…</strong> Prevention of bullying as a factor in the safety of the educational environment is implemented within the framework of programs for the development of communicative competence and emotional self-regulation of students, improvement of the psychological climate and organizational conditions of school functioning. Comprehensive programs covering all participants in the school educational process are most effective. …”
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Associations of prenatal glyphosate exposure with child neurodevelopment in a Canadian pregnancy cohort study by Meaghan Hall, Jillian Ashley-Martin, Christine Till, Janice Hu, Bruce Lanphear, Cynthia Curl, Tye E. Arbuckle, Michel Boivin, Linda Booij, Gina Muckle, Mandy Fisher, Elizabeth Asztalos, Maryse F. Bouchard, Amanda J. MacFarlane, Carly Hyland

“…Social (n = 566) and behavioural (n = 840) functioning were assessed using parent-report versions of the Social Responsiveness Scale-2 and Behavioral Assessment System for Children-2. …”
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Sustained and specific multiplexed immune checkpoint modulation in CAR T cells induced by targeted epigenome editing by Maria Silvia Roman Azcona, Gianni Monaco, Melissa Whitehead, Masako Monika Kaufmann, Jamal Alzubi, Toni Cathomen, Claudio Mussolino

“…Epigenetically modified CAR T cells are indistinguishable from parental cells across a range of functional assays. …”
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Hunger crisis and malnutrition in Pakistan: A word of caution by Umaira Mohamed Imthiyas, Abdul Raheem Rizvie, Muhammed Ifham Mohamed Imtiyas

“…Another contributor, as observed by a study, concluded that one out of every ten children were unvaccinated due to maternal negligence to the purpose of vaccines or fear of the side effects that could present. This, coupled with poor food intake, can render immune-compromised children increasingly susceptible to pneumonia, diarrhoea and other ailments.5 As a significant portion of the problems stem from an absence in understanding, it is highly encouraged that parents obtain comprehensive guidance on the various facets of infant nutrition. …”
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Representation of a Scientific Supervisor in Internet-Memes by N. V. Stepanova, M. S. Sigaeva

“…The study showed that multimodal metaphor is an integral part of modern  Internet communication and is an effective way of influencing the addressee. Internet  memes representing the image of a scientific supervisor were analyzed and systematized;  4 metaphorical mappings (“Scientific supervisor is a loving/caring parent”, “Scientific  supervisor is a Jedi”, “Scientific supervisor is a monster/maniac”, “Scientific supervisor is a  bad boss”) are highlighted and described. …”
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Acute Toxicity of Dinotefuran to <i>Picromerus lewisi</i> Scott (Hemiptera: Pentatomidae) and Its Impact on Offspring Growth and Predation Ability in Integrated Pest Management by Yutong Ji, Mengqing Wang, Chuanzhen Xue, Jianjun Mao, Yuyan Li, Lisheng Zhang

“…The most pronounced effects were observed when both female and male adults were exposed. …”
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Chronic Gestational Inflammation: Transfer of Maternal Adaptation over Two Generations of Progeny by R. C. M. Adams, C. Smith

“…Current data illustrates that parental chronic inflammation may mediate the inflammatory profile in offspring, potentially propagating a maladapted proinflammatory phenotype in subsequent generations.…”
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Evaluating the influence of phosphorus supply on photosynthetic and agronomic performance of two breeding lines of common bean grown under acidic soil and high temperature stress. by Juan Carlos Suárez, José Alexander Anzola, José Ivan Vanegas, Amara Tatiana Contreras, Idupulapati M Rao

“…Increased P supply increased leaf P concentration and alleviated the effects of high temperature on the functioning of the photosynthetic apparatus in both common bean lines (BFS 10 and SEF 10); and accumulation of sugars in pods and seeds facilitated improved seed yield. …”
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Identification and characterization of Sr59-mediated stem rust resistance in a novel wheat-rye translocation T2BL·2BS-2RL by Mahboobeh Yazdani, Matthew N. Rouse, Prabin Bajgain, Tatiana V. Danilova, Ivan Motsnyi, Brian J. Steffenson, Mehran Patpour, Mahbubjon Rahmatov

“…Host resistance is the most effective and environmentally friendly method of controlling stem rust. …”
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Biopsychosocial risk factors for pain in early phases of pediatric cancer treatment by Kimberly L. Klages, Ryan N. James, Zeev N. Kain, Zeev N. Kain, Zeev N. Kain, Sean Phipps, Nicole M. Alberts, Michelle A. Fortier, Michelle A. Fortier

“…Additionally, lower annual income, decreased physical functioning, and greater fatigue, child pain catastrophizing, and parent stress were significantly associated with increased pain interference.DiscussionFindings underscore the importance of utilizing a comprehensive biopsychosocial approach to pain assessment and management in pediatric oncology. …”
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EXPERIENCE IN SOCIAL PARTNERSHIP IN THE SPHERE OF NON-FORMAL ADDITIONAL ART EDUCATION OF CHILDREN by N. Tereshchenko, M. Soldatova, V. Shapovalov

“…The article describes the features and effects of interaction between commercial and non-commercial organizations using two legal models of their functioning, marketing activities, forms offinancial support. …”
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Web-based early intervention for children with motor difficulties aged 3–8 years old using multimodal rehabilitation (WECARE): protocol of a patient-centred pragmatic randomised tr... by Thomas G Poder, Desiree B Maltais, Tibor Schuster, Marie-Claude Battista, Michelle Phoenix, Jean-Patrice Baillargeon, Chantal Camden, Jill G Zwicker, Melanie Morin, Melanie Couture, Mathieu Goyette, Gabrielle Pratte, Karen Hurtubise, Tram Nguyen, Jade Berbari, Michel Tousignant

“…Secondary outcomes include measures of the child’s functional ability, parental knowledge and skills and health-related quality of life, as well as qualitative outcomes pertaining to parental satisfaction and service delivery trajectories. …”
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Innate Immunity Stimulation during the COVID-19 Pandemic: Challenge by Parvulan by Beniamino Palmieri, Antonio Manenti, Francesca Galotti, Maria Vadalà

“…Our results confirm that C. parvum is quite safe and effective in supporting immune-compromised patients when epidemic or pandemic events increase the life risk and any kind of infection and complication rate. …”
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Longitudinal influences of adverse childhood experience patterns on mental health among older Chinese people by Yue Zeng, Renhui Lyu

“…ACE patterns were associated with the trajectory of cognitive function but not depression, and the effects were particularly evident in the Polyvictimization class. …”
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