Design and conduct of a full diet-controlled, parallel, 2-week residential trial for diabetes prevention without weight loss in Asian Chinese and European Caucasian adults with pre... by Ivana R. Sequeira-Bisson, Ivana R. Sequeira-Bisson, Ivana R. Sequeira-Bisson, Karl Fraser, Karl Fraser, Kok Hong Leiu, Kok Hong Leiu, Jack Penhaligan, Jack Penhaligan, Aidan Joblin-Mills, Aidan Joblin-Mills, Lindsay D. Plank, Rinki Murphy, Rinki Murphy, Rinki Murphy, Rinki Murphy, Michael W. Taylor, Michael W. Taylor, Michael W. Taylor, Olivier Gasser, Olivier Gasser, Denise M. Conroy, Denise M. Conroy, Yannan Jiang, Louise W. W. Lu, Louise W. W. Lu, Sally D. Poppitt, Sally D. Poppitt, Sally D. Poppitt, Sally D. Poppitt, Jennifer L. Miles-Chan, Jennifer L. Miles-Chan, Jennifer L. Miles-Chan

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Effects of opioid-free anesthesia combined with iliofascial nerve block on perioperative neurocognitive deficits in elderly patients undergoing hip fracture surgery: study protocol... by Tong Zhi, Shirong Wei, Jiao Kuang, Sitong Zhou, Danhong Yu, Tesheng Gao, Long Lei, Chengfei Xu, Liang Cheng, Qinghe Zhou, Ming Yao, Huadong Ni

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Single-blinded, randomised, parallel-group, controlled trial comparing the efficacy and cost-effectiveness of therapist- and self-guided internet-delivered behavioural activation v... by Matteo Bottai, David Mataix-Cols, Eva Serlachius, Fabian Lenhard, Sarah Vigerland, Johan Åhlén, Rebecca Andersson

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eHealth versus face-to-face support for remission of type 2 diabetes by calorie restriction (eHealth DIabetes remission Trial): study protocol for a non-inferiority parallel group... by Lars Lindholm, Per Liv, Julia Otten, Anna Winkvist, Andreas Stomby, Youssef Chninou, Anna Tellström, Claudia Schien

“…Our second hypothesis is that eHealth support will be more cost-effective than face-to-face support.Methods and analysis The eHealth DIabetes remission Trial is a multicentre, two-arm, non-inferiority, open-label, randomised controlled parallel group trial with blinded endpoint assessment conducted at two centres in Sweden. …”
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Rationale and design of a randomised, double-blind, placebo-controlled, parallel-group, investigator-initiated phase 2a study to investigate the efficacy and safety of elobixibat i... by Atsushi Nakajima, Takeharu Yamanaka, Koji Yamamoto, Yasushi Honda, Kento Imajo, Masato Yoneda, Yuji Ogawa, Takaomi Kessoku, Takashi Kobayashi, Anna Ozaki, Satoru Saito, Michihiro Iwaki, Yusuke Saigusa, Haruki Usuda, Koichiro Wada

“…The results of this study will be submitted for publication in international peer-reviewed journals and the key findings will be presented at international scientific conferences.Trial registration number NCT04235205…”
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Study protocol for the COMET study: a cluster-randomised, prospective, parallel-group, superiority trial to compare the effectiveness of a collaborative and stepped care model vers... by Hans-Helmut König, Olaf von dem Knesebeck, Karl Wegscheider, Martin Härter, Jörg Dirmaier, Bernd Löwe, Bernd Schulte, Daniela Heddaeus, Christian Brettschneider, Anne Daubmann, Thomas Grochtdreis, Kerstin Maehder, Sarah Porzelt, Moritz Rosenkranz, Ingo Schäfer, Martin Scherer, Angelika Weigel, Silke Werner, Thomas Zimmermann

“…Within the superordinate research project Hamburg Network for Health Services Research, the results will be communicated to relevant stakeholders in mental healthcare.Trial registration number NCT03226743.…”
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Airborne laser scanning data quality enhancement via rigorous calibration and comprehensive strip adjustment techniques by Qingeng Jin, Qingwu Hu, Xuzhe Duan, Pengcheng Zhao, Zijie Li, Jiayuan Li, Qingzhou Mao

“…Besides, notable advantages in efficiency and convenience are achieved with paralleling strategy and automated workflow. In summary, our contributions include accuracy improvement, the facilitation of user convenience through an automated workflow, while ensuring processing efficiency via a paralleling strategy. …”
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Mamba-Based VoxelMorph Framework for Cardiovascular Disease Imaging and Risk Assessment by Muhammad Kashif Jabbar, Huang Jianjun, Ayesha Jabbar, Zaka Ur Rehman

“…This study proposes the Mamba-Optimized VoxelMorph framework, which leverages GPU-based parallelization and memory optimization to address these challenges. …”
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Effects of the different intensities of task-oriented training on the upper extremity motor function and self-care ability of stroke survivors: study protocol for a multiarm parall... by Kai Zhang, Chunxiang Li, Shengfeng Liu, Xuecha Li, Mengsi Peng

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The impact of blood flow restriction training combined with low-load resistance training on the risk of falls in patients with knee osteoarthritis in China: a single-centre, two-ar... by Yuping Zhang, Xiaoting Chen, Qiuxiang Lin, DeBiao Yu, Tianxiang Lu, Jiawei Qin, Fuchun Wu

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Cost-effectiveness of C-reactive protein point of care testing for safely reducing antibiotic consumption for acute exacerbations of chronic obstructive pulmonary disease as part o... by David Gillespie, Kerenza Hood, Deborah Fitzsimmons, Bernadette Sewell, Nick Francis, Christopher C Butler, Patrick White, Shaun Harris, Janine Bates, Mohammed Fasihul Alam

“…There is a 73% probability of CRP-POCT being cost-effective at WTP ≤£20 000 per QALY gained.Conclusion CRP-POCT is a cost-effective intervention for safely reducing antibiotic consumption in patients with AECOPD.Trial registration number ISRCTN24346473…”
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Effect of remimazolam tosilate for injection (HR7056) versus sevoflurane on the incidence of postoperative delirium in older patients undergoing total hip arthroplasty: study proto... by Lin-yu Wang, Meng-qing Zhang, Rui Sun, Liang Li, Dong-liang Li

“…Methods and analysis This is a two-arm, parallel, prospective, multicenter, randomized controlled trial. …”
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Investigating the effect of verapamil on preservation of beta-cell function in adults with newly diagnosed type 1 diabetes mellitus (Ver-A-T1D): protocol for a randomised, double-b... by Piotr Jaroslaw Chmura, Thomas Danne, Colin Dayan, Thomas R Pieber, Chantal Mathieu, Rachel Stenson, Julie Wych, Martina Brunner, Adrian Paul Mander

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Comparison of ultrasound-guided anterior quadratus lumborum block at the lateral supra-arcuate ligament with posterior quadratus lumborum block for perioperative analgesia in lapar... by Yun Wang, Rong Shi, Xiao Huang, Yinan Yang, Yuan Sun, Danxu Ma, Anshi Wu

“…The trial results will be published in peer-reviewed journals and at conferences.Trial registration number ChiCTR2000035354.…”
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Protocol for a single-centre, parallel-group, randomised, controlled, superiority trial on the effects of time-restricted eating on body weight, behaviour and metabolism in individ... by Marit E Jørgensen, Graham Finlayson, Dorte Vistisen, Jonas S Quist, Marie M Jensen, Kim K B Clemmensen, Hanne Pedersen, Natasja Bjerre, Joachim Størling, Martin B Blond, Nicolai J Wewer Albrechtsen, Jens J Holst, Signe S Torekov, Satchidananda Panda, Christina Brock, Kristine Færch

“…Results from the study will address whether TRE is effective and feasible in improving health outcomes in individuals at risk of lifestyle-related diseases and can potentially inform the design of feasible health recommendations.Trial registration number NCT03854656.…”
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Active Touch Sensing for Robust Hole Detection in Assembly Tasks by Bojan Nemec, Mihael Simonič, Aleš Ude

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Effects of almond consumption compared with the consumption of traditional isocaloric cereal/pulse-based snacks on glycaemic control and gut health in adults with pre-diabetes in r... by N Sreekumaran Nair, Vaidya Ruchi, Chaudhury Nayanjeet, Pramila Kalra, Bellur Prabhakar

“…Results from this trial will be disseminated through publication in peer-reviewed journals and scientific gatherings.Trial registration number Clinical Trial Registry of India (CTRI/2023/03/050421).…”
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Wise or wide (WoW) study protocol: a national, multicentre, prospective, randomised and controlled, parallel group, non-inferiority study to compare single-staged versus two-staged... by Roger Olofsson Bagge, Ebba Wennberg, Magdalena Claeson, Sam Polesie, John Paoli

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Efficacy, safety and cost-effectiveness of methotrexate, adalimumab or their combination in non-infectious non-anterior uveitis: a protocol for a multicentre, randomised, parallel... by José Antonio Pinto, Alex Fonollosa, Ester Carreño, Maria Isabel Rodriguez, David Diaz-Valle, Diana Peiteado, Luis Rodriguez-Rodriguez, Miguel Cordero-Coma, Marta Tejera Santana, Lidia Cocho, Ana Belen Rivas, Amanda Lopez-Picado, Valentina Calamia, Felix M Francisco Hernandez, Angel Garcia-Aparicio, Javier Garcia-Gonzalez, Jose Juan Mondejar, Leticia Lojo-Oliveira, Llucí Martínez-Costa, Santiago Munoz, Beatriz Rodriguez-Lozano, Esperanza Pato, Elena Molina, Luis Alberto Tebar, Mara Albert Fort, Mayte Ariño Gutierrez, Pedro Arriola Villalobos, Joseba Artaraz Beobide, Antonio Atanes Sandoval, Jose Manuel Sanchez, Francisco Blázquez, Pablo Borges Deniz, Lara Borrego Sanz, Gabriela Bustamante Sanchez-Arnedo, Bruno Casco Silva, Ricardo Cuiña Sardiña, Almudena De Pablo Cabrera, Maria Del Mar Esteban Ortega, Patricia Fernandez Puente, Dalifer Dayanira Nuñez, Javier Garcia Bella, Sara Garcia Carazo, Luis Garcia Onrubia, Jose Maria Morales, Jose Antonio Fernandez, Vanesa Hernandez Hernandez, Inés Hernanz Rodriguez, Jose Maria Cantalapiedra, Ventura Hidalgo Barrero, Maria De Jovani Casano, Sara López Sierra, Virginia Lozano Lopez, Alfredo Madrid Garcia, Rosalia Mendez Fernandez, Pilar Nozal Aranda, Eugenio Perez Blazquez, Chamaida Plasencia Rodriguez, Sheila Recuero Diaz, Ignacio Robles Barrena, Esther Rodriguez Almaraz, Fayna Maria Gonzalez, Guadalupe Rodriguez Martinez, Fredeswinda Isabel Bueno, Ioana Ruiz Arruza, Beatriz Sanchez Marugan, Olga Sanchez Pernaute, Armelle Schlinker Giraud, Alvaro Seijas Lopez, Patricia Simon Alonso, Elia Valls Pascual

“…The promoter will be the only access to the participant-level data, although it can be shared within the legal situation.Trial registration number 2020-000130-18; NCT04798755.…”
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Effects of basic carbohydrate counting versus standard outpatient nutritional education (The BCC Study): study protocol for a randomised, parallel open-label, intervention study fo... by Bettina Ewers, Tina Vilsbøll, Jens Meldgaard Bruun

“…Study findings will be disseminated widely through peer-reviewed publications and conference presentations.Trial registration number NCT03623139.…”
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